A short-term in vivo experimental model for fuchs endothelial corneal dystrophy

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 10, 2012, Pages 6343-6354

  Nour Haydari, M ^a,b   Perron, Marie Claude ^a   Laprise, Simon ^c   Roy, Olivier ^c   Douglas Cameron, J ^d,e   Proulx, Stéphanie ^c   Brunette, Isabelle ^a,b  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c LAVAL UNIVERSITY   (Canada)

^d UNIVERSITÉ LAVAL   (Canada)

^e UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETAMETHASONE; CEFAZOLIN; DEXAMETHASONE; TOBRAMYCIN;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAT; CELL COUNT; CELL DENSITY; CLINICAL ARTICLE; CONGENITAL CORNEA DYSTROPHY; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CORNEA OPACITY; CORNEA TRANSPLANTATION; CORNEAL PACHYMETRY; EPITHELIZATION; EYE INFLAMMATION; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; INTRAOCULAR PRESSURE; MALE; MORPHOMETRICS; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; TISSUE ENGINEERING; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; DISEASE MODEL; ENDOTHELIUM CELL; EYEBANK; METHODOLOGY; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; POSTOPERATIVE COMPLICATION; PRIMARY CELL CULTURE; ULTRASTRUCTURE; XENOGRAFT;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CATS; CELL COUNT; CORNEAL PACHYMETRY; CORNEAL TRANSPLANTATION; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; ENDOTHELIUM, CORNEAL; EYE BANKS; FEMALE; FUCHS' ENDOTHELIAL DYSTROPHY; HUMANS; INTRAOCULAR PRESSURE; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PRIMARY CELL CULTURE; TISSUE ENGINEERING; TRANSPLANTATION, HETEROLOGOUS;

EID: 84871688815     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-9708     Document Type: Article

References (54)

1. 2010 Eye Banking Statistical Report. Washington, DC: Eye Bank Association of America; 2011:18.
2. Rosenblum P, Stark WJ, Maumenee IH, Hirst LW, Maumenee AE. Hereditary Fuchs' dystrophy. Am J Ophthalmol. 1980;90:455-462.
3. Afshari NA, Li YJ, Pericak-Vance MA, Gregory S, Klintworth GK. Genome-wide linkage scan in Fuchs endothelial corneal dystrophy. Invest Ophthalmol Vis Sci. 2009;50:1093-1097.
4. Louttit MD, Kopplin LJ, Igo RP Jr, et al. A multicenter study to map genes for Fuchs endothelial corneal dystrophy: baseline characteristics and heritability. Cornea. 2012;31:26-35.
5. Burns RR, Bourne WM, Brubaker RF. Endothelial function in patients with cornea guttata. Invest Ophthalmol Vis Sci. 1981; 20:77-85.
6. Geroski DH, Matsuda M, Yee RW, Edelhauser HF. Pump function of the human corneal endothelium. Effects of age and cornea guttata. Ophthalmology. 1985;92:759-763.
7. Wilson SE, Bourne WM, O'Brien PC, Brubaker RF. Endothelial function and aqueous humor flow rate in patients with Fuchs' dystrophy. Am J Ophthalmol. 1988;106:270-278.
8. McCartney MD, Robertson DP, Wood TO, McLaughlin BJ. ATPase pump site density in human dysfunctional corneal endothelium. Invest Ophthalmol Vis Sci. 1987;28:1955-1962.
9. McCartney MD, Wood TO, McLaughlin BJ. Immunohistochemical localization of ATPase in human dysfunctional corneal endothelium. Curr Eye Res. 1987;6:1479-1486.
10. McCartney MD, Wood TO, McLaughlin BJ. Moderate Fuchs' endothelial dystrophy ATPase pump site density. Invest Ophthalmol Vis Sci. 1989;30:1560-1564.
11. Borderie VM, Baudrimont M, Vallee A, Ereau TL, Gray F, Laroche L. Corneal endothelial cell apoptosis in patients with Fuchs' dystrophy. Invest Ophthalmol Vis Sci. 2000;41:2501-2505.
12. Jurkunas UV, Bitar MS, Funaki T, Azizi B. Evidence of oxidative stress in the pathogenesis of Fuchs endothelial corneal dystrophy. Am J Pathol. 2010;177:2278-2289.
13. Jurkunas UV, Bitar MS, Rawe I, Harris DL, Colby K, Joyce NC. Increased clusterin expression in Fuchs' endothelial dystrophy. Invest Ophthalmol Vis Sci. 2008;49:2946-2955.
14. Jurkunas UV, Rawe I, Bitar MS, et al. Decreased expression of peroxiredoxins in Fuchs' endothelial dystrophy. Invest Ophthalmol Vis Sci. 2008;49:2956-2963.
15. Azizi B, Ziaei A, Fuchsluger T, Schmedt T, Chen Y, Jurkunas UV. p53-regulated increase in oxidative-stress-induced apoptosis in Fuchs endothelial corneal dystrophy: a native tissue model. Invest Ophthalmol Vis Sci. 2011;52:9291-9297.
16. Engler C, Kelliher C, Spitze AR, Speck CL, Eberhart CG, Jun AS. Unfolded protein response in fuchs endothelial corneal dystrophy: a unifying pathogenic pathway? Am J Ophthalmol. 2010;149:194-202.
17. Jun AS, Meng H, Ramanan N, et al. An alpha 2 collagen VIII transgenic knock-in mouse model of Fuchs endothelial corneal dystrophy shows early endothelial cell unfolded protein response and apoptosis. Hum Mol Genet. 2011;21:384-393.
18. He Y, Weng J, Li Q, Knauf HP, Wilson SE. Fuchs' corneal endothelial cells transduced with the human papilloma virus E6/E7 oncogenes. Exp Eye Res. 1997;65:135-142.
19. Joyce NC, Meklir B, Joyce SJ, Zieske JD. Cell cycle protein expression and proliferative status in human corneal cells. Invest Ophthalmol Vis Sci. 1996;37:645-655.
20. Joyce NC. Proliferative capacity of the corneal endothelium. Prog Retin Eye Res. 2003;22:359-389.
21. Joyce NC, Zhu CC. Human corneal endothelial cell proliferation: potential for use in regenerative medicine. Cornea. 2004; 23:S8-S19.
22. Zhu C, Joyce NC. Proliferative response of corneal endothelial cells from young and older donors. Invest Ophthalmol Vis Sci. 2004;45:1743-1751.
23. Proulx S, Audet C, Uwamaliya J, et al. Tissue engineering of feline corneal endothelium using a devitalized human cornea as carrier. Tissue Eng Part A. 2009;15:1709-1718.
24. Proulx S, d'Arc Uwamaliya J, Carrier P, et al. Reconstruction of a human cornea by the self-assembly approach of tissue engineering using the three native cell types. Mol Vis. 2010; 16:2192-2201.
25. Proulx S, Bensaoula T, Nada O, et al. Transplantation of a tissueengineered corneal endothelium reconstructed on a devitalized carrier in the feline model. Invest Ophthalmol Vis Sci. 2009;50: 2686-2694.
26. Zaniolo K, Bostan C, Rochette Drouin O, et al. Culture of human corneal endothelial cells isolated from corneas with Fuchs endothelial corneal dystrophy. Exp Eye Res. 2012;94:22-31.
27. Goyer B, Haydari MN, Drouin OR, et al. Tissue engineering of a corneal endothelium using cells from patients with Fuchs endothelial corneal dystrophy. Tissue Eng. In press.
28. Brunette I, Rosolen SG, Carrier M, et al. Comparison of the pig and feline models for full thickness corneal transplantation. Vet Ophthalmol. 2011;14:365-377.
29. Schlaegel TJ. Essentials of Uveitis. Boston: Little, Brown & Co; 1969.
30. Bahn CF, MacCallum DK, Lillie JH, Meyer RF, Martonyi CL. Complications associated with bovine corneal endothelial celllined homografts in the cat. Invest Ophthalmol Vis Sci. 1982; 22:73-90.
31. Taylor MJ, Hunt CJ. Dual staining of corneal endothelium with trypan blue and alizarin red S: importance of pH for the dye-lake reaction. Br J Ophthalmol. 1981;65:815-819.
32. Matsuda M, Bourne WM. Long-term morphologic changes in the endothelium of transplanted corneas. Arch Ophthalmol. 1985; 103:1343-1346.
33. McCarey BE, Edelhauser HF, Lynn MJ. Review of corneal endothelial specular microscopy for FDA clinical trials of refractive procedures, surgical devices, and new intraocular drugs and solutions. Cornea. 2008;27:1-16.
34. Short BG. Safety evaluation of ocular drug delivery formulations: techniques and practical considerations. Toxicol Pathol. 2008; 36:49-62.
35. Yuen HK, Rassier CE, Jardeleza MS, et al. A morphologic study of Fuchs dystrophy and bullous keratopathy. Cornea. 2005;24: 319-327.
36. Iwamoto T, DeVoe AG. Electron microscopic studies on Fuchs' combined dystrophy. I. Posterior portion of the cornea. Invest Ophthalmol. 1971;10:9-28.
37. Bourne WM, Johnson DH, Campbell RJ. The ultrastructure of Descemet's membrane. III. Fuchs' dystrophy. Arch Ophthalmol. 1982;100:1952-1955.
38. Waring GO 3rd. Posterior collagenous layer of the cornea. Ultrastructural classification of abnormal collagenous tissue posterior to Descemet's membrane in 30 cases. Arch Ophthalmol. 1982;100:122-134.
39. Iwamoto T, Smelser GK. Electron microscopy of the human corneal endothelium with reference to transport mechanisms. Invest Ophthalmol. 1965;4:270-284.
40. Bergmanson JP, Sheldon TM, Goosey JD. Fuchs' endothelial dystrophy: a fresh look at an aging disease. Ophthalmic Physiol Opt. 1999;19:210-222.
41. Bloomfield SE, Jakobiec FA, Iwamoto T, Harrison WG. Retrocorneal pigmentation secondary to iris stromal melanocytic proliferation. Ophthalmology. 1981;88:1274-1280.
42. Gottsch JD, Zhang C, Sundin OH, Bell WR, Stark WJ, Green WR. Fuchs corneal dystrophy: aberrant collagen distribution in an L450W mutant of the COL8A2 gene. Invest Ophthalmol Vis Sci. 2005;46:4504-4511.
43. Kayes J, Holmberg A. The fine structure of the cornea in Fuchs' endothelial dystrophy. Invest Ophthalmol. 1964;3:47-67.
44. Van Horn DL, Sendele DD, Seideman S, Buco PJ. Regenerative capacity of the corneal endothelium in rabbit and cat. Invest Ophthalmol Vis Sci. 1977;16:597-613.
45. Tuft SJ, Williams KA, Coster DJ. Endothelial repair in the rat cornea. Invest Ophthalmol Vis Sci. 1986;27:1199-1204.
46. Nakahori Y, Katakami C, Yamamoto M. Corneal endothelial cell proliferation and migration after penetrating keratoplasty in rabbits. Jpn J Ophthalmol. 1996;40:271-278.
47. Joyce NC, Meklir B, Neufeld AH. In vitro pharmacologic separation of corneal endothelial migration and spreading responses. Invest Ophthalmol Vis Sci. 1990;31:1816-1826.
48. Bahn CF, Glassman RM, MacCallum DK, et al. Postnatal development of corneal endothelium. Invest Ophthalmol Vis Sci. 1986;27:44-51.
49. Giasson CJ, Gosselin L, Masella A, Forcier P. Does endothelial cell density correlate with corneal diameter in a group of young adults? Cornea. 2008;27:640-643.
50. Gonzalez-Perez J, Gonzalez-Meijome JM, Rodriguez Ares MT, Parafita MA. Central corneal thickness measured with three optical devices and ultrasound pachometry. Eye Contact Lens. 2011;37:66-70.
51. Bourne WM, Nelson LR, Buller CR, Huang PT, Geroski DH, Edelhauser HF. Long-term observation of morphologic and functional features of cat corneal endothelium after wounding. Invest Ophthalmol Vis Sci. 1994;35:891-899.
52. Carrington SD, Woodward EG. Corneal thickness and diameter in the domestic cat. Ophthalmic Physiol Opt. 1986;6:385-389.
53. Ohno K, Nelson LR, Mitooka K, Bourne WM. Transplantation of cryopreserved human corneas in a xenograft model. Cryobiology. 2002;44:142-149.
54. Bahn CF, Meyer RF, MacCallum DK, et al. Penetrating keratoplasty in the cat. A clinically applicable model. Ophthalmology. 1982;89:687-699.