Electrical stimulation enhances neurogenin2 expression through β-catenin signaling pathway of mouse bone marrow stromal cells and intensifies the effect of cell transplantation on brain injury

Neuroscience Letters

Volumn 533, Issue 1, 2013, Pages 71-76

  Matsumoto, Masaya ^a   Imura, Takeshi ^a   Fukazawa, Takahiro ^a   Sun, Yanan ^a   Takeda, Masaaki ^a   Kajiume, Teruyuki ^a   Kawahara, Yumi ^b   Yuge, Louis ^a,b  

^a HIROSHIMA UNIVERSITY   (Japan)

^b Cell Therapy Venture Company   (Japan)

Author keywords

catenin; Bone marrow stromal cells; Electrical stimulation; Neural differentiation; Neurogenin2

Indexed keywords

BETA CATENIN; NEUROGENIN 2;

ANIMAL CELL; ARTICLE; ASTROCYTE; BONE MARROW; BRAIN INJURY; CELL GROWTH; CELL TRANSPLANTATION; CONTROLLED STUDY; ELECTROSTIMULATION; MALE; MOUSE; NERVE CELL; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STROMA CELL; TRAUMATIC BRAIN INJURY;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA CATENIN; BIOLOGICAL MARKERS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; BRAIN INJURIES; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; ELECTRIC STIMULATION; MALE; MICE; MICE, INBRED C57BL; MOVEMENT; NERVE TISSUE PROTEINS; NEURONS; SIGNAL TRANSDUCTION; STROMAL CELLS;

EID: 84871680752     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.10.023     Document Type: Article

References (14)

1. Chen J., Li Y., Chopp M. Intracerebral transplantation of bone marrow with BDNF after MCAO in rat. Neuropharmacology 2000, 39:711-716.
2. Chen J., Li Y., Katakowski M., Chen X., Wang L., Lu D., Gautam M.S.C., Chopp M. Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat. Journal of Neuroscience Research 2003, 73:778-786.
3. Hofstetter C.P., Holmstrom N.A., Lilja J.A., Schweinhardt P., Hao J., Spenger C., Wiesenfeld-Hallin Z., Kurpad S.N., Frisen J., Olson L. Allodynia limits the usefulness of intraspinal neural stem cell grafts; directed differentiation improves outcome. Nature Neuroscience 2005, 8:346-353.
4. Hong G.M., Bain L.J. Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the B-catenin signaling pathway. Toxicological Sciences 2012, 129:146-156.
5. Jiang Y., Jahagirdar B.N., Reinhardt R.I., Schwartz R.E., Keene C.D., Ortiz-Gonzalez X.R., Reyes M., Lenvik T., Lund T., Blackstad M., Du J., Aldrich S., Lisberg A., Low W.C., Largaespada D.A., Verfaillie C.M. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002, 418:41-49.
6. Kimura K., Yanagida Y., Haruyama T., Kobatake E., Aizawa M. Gene expression in the electrically stimulated differentiation of PC12 cells. Journal of Biotechnology 1998, 63:55-65.
7. Kondo T., Matsuoka A.J., Shimomura A., Koehler K.R., Chan R.J., Miller J.M., Srour E.F., Hashino E. Wnt signaling promotes neuronal differentiation from mesenchymal stem cells through activation of Tlx3. Stem Cells 2011, 29:836-846.
8. Lei Z., Yongda L., Jun M., Yingyu S., Shaoju Z., Xinwen Z., Mingxue Z. Culture and neural differentiation of rat bone marrow mesenchymal stem cells in vitro. Cell Biology International 2007, 31:916-923.
9. Lu D., Mahmood A., Wang L., Li Y., Lu M., Chopp M. Adult bone marrow stromal cells administered intravenously to rats after traumatic brain injury migrate into brain and improve neurological outcome. Neuroreport 2001, 12:559-563.
10. Nomura T., Honmou O., Harada K., Houkin K., Hamada H., Kocsis J.D. I.V. infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Neuroscience 2005, 136:161-169.
11. Qu R., Li Y., Gao Q., Shen L., Zhang J., Liu Z., Chen X., Chopp M. Neurotrophic and growth factor gene expression profiling of mouse bone marrow stromal cells induced by ischemic brain extracts. Neuropathology 2007, 27:355-363.
12. Reya T., Clevers H. Wnt signaling in stem cells and cancer. Nature 2005, 14:843-850.
13. Yamada M., Tanemura K., Okada S., Iwanami A., Nakamura M., Mizuno H., Ozawa M., Ohymama-Goto R., Kitamura N., Kawano M., Tan-Takeuchi K., Ohtsuka C., Miyawaki A., Takashima A., Ogawa M., Toyama Y., Okano H., Kondo T. Electrical stimulation modulates fate determination of differentiating embryonic stem cells. Stem Cells 2007, 25:562-570.
14. Yi S.H., Jo A.Y., Park C.H., Koh H.C., Park R.H., Suh-Kim H., Shin I., Lee Y.S., Kim J., Lee S.H. Mash 1 and neurogenin 2 enhance survival and differentiation of neural precursor cells after transplantation to rat brains via distinct modes of action. Molecular Therapy 2008, 16:1873-1882.