Glucose-Induced Down Regulation of Thiamine Transporters in the Kidney Proximal Tubular Epithelium Produces Thiamine Insufficiency in Diabetes

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Larkin, James R ^a   Zhang, Fang ^a   Godfrey, Lisa ^a   Molostvov, Guerman ^a   Zehnder, Daniel ^a   Rabbani, Naila ^a   Thornalley, Paul J ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; MESSENGER RNA; THIAMINE; THIAMINE DERIVATIVE; THIAMINE PYROPHOSPHATASE; THIAMINE TRANSPORTER PROTEIN; THIAMINE TRANSPORTER PROTEIN 1; THIAMINE TRANSPORTER PROTEIN 2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DOWN REGULATION; ENZYME PHOSPHORYLATION; FOOD INTAKE; GLYCEMIC CONTROL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KIDNEY CLEARANCE; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY PROXIMAL TUBULE; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; STREPTOZOCIN DIABETES; THIAMINE DEFICIENCY;

ANIMALS; CELLS, CULTURED; DIABETES MELLITUS; DIABETIC NEPHROPATHIES; DOWN-REGULATION; EPITHELIUM; GLUCOSE; HUMANS; KIDNEY TUBULES, PROXIMAL; MALE; MEMBRANE TRANSPORT PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; THIAMINE; THIAMINE DEFICIENCY;

EID: 84871677878     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053175     Document Type: Article

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