Differential regulation of fibrinogen γ chain splice isoforms by interleukin-6

Thrombosis Research

Volumn 131, Issue 1, 2013, Pages 89-93

  Rein Smith, Chantelle M ^a,c   Anderson, Nathan W ^b   Farrell, David H ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokines; Expression; Fibrinogen; Inflammation; Liver

Indexed keywords

FIBRINOGEN; FIBRINOGEN GAMMA CHAIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; FIBRINOGEN SYNTHESIS; HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRINOGENS, ABNORMAL; HEP G2 CELLS; HEPATOCYTES; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MAP KINASE KINASE KINASES; PHOSPHORYLATION; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84871663311     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2012.09.017     Document Type: Article

References (34)

1. R.S. Lovely, L.A. Falls, H.A. Al-Mondhiry, C.E. Chambers, G.J. Sexton, and H. Ni Association of γA/γ' fibrinogen levels and coronary artery disease Thromb Haemost 88 2002 26 31 (Pubitemid 34752262)
2. L. Drouet, F. Paolucci, N. Pasqualini, M. Laprade, L. Ripoll, and E. Mazoyer Plasma γ'/γ fibrinogen ratio, a marker of arterial thrombotic activity: A new potential cardiovascular risk factor? Blood Coagul Fibrinolysis 10 S1 1999 128
3. M.N. Mannila, R.S. Lovely, S.C. Kazmierczak, P. Eriksson, A. Samnegård, and D.H. Farrell Elevated plasma fibrinogen γ' concentration is associated with myocardial infarction: Effects of variation in fibrinogen genes and environmental factors J Thromb Haemost 5 2007 766 773 (Pubitemid 46563576)
4. E.Y. Cheung, H.L. Vos, M.J. Kruip, H.M. den Hertog, J.W. Jukema, and M.P. de Maat Elevated fibrinogen γ' ratio is associated with cardiovascular diseases and acute phase reaction but not with clinical outcome Blood 114 2009 4603 4604
5. E.Y. Cheung, S.U. de Willige, H.L. Vos, F.W. Leebeek, D.W. Dippel, and R.M. Bertina Fibrinogen γ' in ischemic stroke: A case-control study Stroke 39 2008 1033 1035 (Pubitemid 351619556)
6. K.S. Alexander, T.E. Madden, and D.H. Farrell Association between γ' fibrinogen levels and inflammation Thromb Haemost 105 2011 605 609
7. P. Libby, P.M. Ridker, and G.K. Hansson Leducq Transatlantic Network on Atherothrombosis. Inflammation in atherosclerosis: from pathophysiology to practice J Am Coll Cardiol 54 2009 2129 2138
8. R.S. Lovely, S.C. Kazmierczak, J.M. Massaro, R.B. D'Agostino Sr., C.J. O'Donnell, and D.H. Farrell γ' fibrinogen: evaluation of a new assay for study of associations with cardiovascular disease Clin Chem 56 2010 781 788
9. D.W. Chung, and E.W. Davie γ and γ' chains of human fibrinogen are produced by alternative mRNA processing Biochemistry 23 1984 4232 4236 (Pubitemid 14042050)
10. A.J. Fornace, D.E. Cummings, C.M. Comeau, J.A. Kant, and G.R. Crabtree Structure of the human γ-fibrinogen gene. alternate mRNA splicing near the 3' end of the gene produces γA and γB forms of γ-fibrinogen J Biol Chem 259 1984 12826 12830 (Pubitemid 15211186)
11. J.P. Collet, C. Nagaswami, D.H. Farrell, G. Montalescot, and J.W. Weisel Influence of γ' fibrinogen splice variant on fibrin physical properties and fibrinolysis rate Arterioscler Thromb Vasc Biol 24 2004 382 386 (Pubitemid 38197594)
12. B.B. Knowles, C.C. Howe, and D.P. Aden Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen Science 209 1980 497 499
13. D.H. Farrell, E.R. Mulvihill, S. Huang, D.W. Chung, and E.W. Davie Recombinant human fibrinogen and sulfation of the γ' chain Biochemistry 30 1991 9414 9420
14. A. Mackiewicz, T. Speroff, M. Ganapathi, and I. Kushner Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines J Immunol 146 1991 3032 3037
15. A.E. Schorer, C.F. Moldow, and M.E. Rick Interleukin 1 or endotoxin increases the release of von Willebrand factor from human endothelial cells Br J Haematol 67 1987 193 197 (Pubitemid 18029653)
16. R. Nachman, K. Hajjar, R. Silverstein, and C.A. Dinarello Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor J Exp Med 163 1986 1595 1600 (Pubitemid 16043476)
17. P.P. Nawroth, D.A. Handley, C.T. Esmon, and D.M. Stern Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity Proc Natl Acad Sci U S A 83 1986 3460 3464 (Pubitemid 16051992)
18. A. Sahni, M. Guo, S.K. Sahni, and C.W. Francis Interleukin-1β but not interleukin-1α binds to fibrinogen and fibrin and has enhanced activity in the bound form Blood 104 2004 409 414 (Pubitemid 38900022)
19. D.J. Grainger TGF-β and atherosclerosis in man Cardiovasc Res 74 2007 213 222
20. J.H. Hassan, C. Chelucci, C. Peschle, and V. Sorrentino Transforming growth factor β (TGF-β) inhibits expression of fibrinogen and factor VII in a hepatoma cell line Thromb Haemost 67 1992 478 483
21. A. Mackiewicz, M.K. Ganapathi, D. Schultz, A. Brabenec, J. Weinstein, and M.F. Kelley Transforming growth factor β1 regulates production of acute-phase proteins Proc Natl Acad Sci U S A 87 1990 1491 1495
22. L. Riipi, and E. Carlson Tumor necrosis factor (TNF) is induced in mice by Candida albicans: Role of TNF in fibrinogen increase Infect Immun 58 1990 2750 2754 (Pubitemid 20267656)
23. H.O. Duan, and P.J. Simpson-Haidaris Functional analysis of interleukin 6 response elements (IL-6REs) on the human γ-fibrinogen promoter J Biol Chem 278 2003 41270 41281
24. Z. Zhang, N.L. Fuentes, and G.M. Fuller Characterization of the IL-6 responsive elements in the γ fibrinogen gene promoter J Biol Chem 270 1995 24287 24291
25. S. Uitte de Willige, K.F. Standeven, H. Philippou, and R.A. Ariëns The pleiotropic role of the fibrinogen γ' chain in hemostasis Blood 114 2009 3994 4001
26. Farrell DH. γ' fibrinogen as a novel marker of thrombotic disease. Clin Chem Lab Med in press.
27. Z. Zhang, and G.M. Fuller Interleukin 1β inhibits interleukin 6-mediated rat γ fibrinogen gene expression Blood 96 2000 3466 3472
28. J. Mizuguchi, C.H. Hu, Z. Cao, K.R. Loeb, D.W. Chung, and E.W. Davie Characterization of the 5'-flanking region of the gene for the γ chain of human fibrinogen J Biol Chem 270 1995 28350 28356
29. N. Matter, P. Herrlich, and H. Konig Signal-dependent regulation of splicing via phosphorylation of Sam68 Nature 420 2002 691 695 (Pubitemid 36764503)
30. C.Y. Li, J.Y. Chu, J.K. Yu, X.Q. Huang, X.J. Liu, and L. Shi Regulation of alternative splicing of Bcl-x by IL-6, GM-CSF and TPA Cell Res 14 2004 473 479 (Pubitemid 43231792)
31. S. Weg-Remers, H. Ponta, P. Herrlich, and H. König Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway EMBO J 20 2001 4194 4203 (Pubitemid 32751835)
32. H. Kim, and H. Baumann Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells Mol Cell Biol 19 1999 5326 5338 (Pubitemid 29339892)
33. S.V. Kalivendi, D. Yedlapudl, C.J. Hillard, and B. Kalyanaraman Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's Disease Free Radic Biol Med 48 2010 377 383
34. E.W. Robbins, E.A. Travanty, K. Yang, and K.A. Iczkowski MAP kinase pathways and calcitonin influence CD44 alternate isoform expression in prostate cancer cells BMC Cancer 8 2008 260