Association between γ'fibrinogen levels and inflammation

Thrombosis and Haemostasis

Volumn 105, Issue 4, 2011, Pages 605-609

  Alexander, Kristine S ^a   Madden, Theresa E ^b   Farrell, David H ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b PLLC   (United States)

Author keywords

Cardiovascular disease 'fibrinogen; Inflammation; Periodontitis; Risk factor

Indexed keywords

AUTACOID; BIOLOGICAL MARKER; C REACTIVE PROTEIN; FIBRINOGEN; GAMMA FIBRINOGEN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; CARDIOVASCULAR DISEASE; CAUCASIAN; CIGARETTE SMOKING; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEMOGRAPHY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ETHNIC DIFFERENCE; FEMALE; HEALTH STATUS; HISPANIC; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; NEGRO; PERIODONTITIS; PRIORITY JOURNAL; RACE DIFFERENCE; RISK ASSESSMENT; RISK FACTOR;

AGED; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; CROSS-SECTIONAL STUDIES; FEMALE; FIBRINOGEN; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; PERIODONTITIS; RISK;

EID: 79955389453     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-09-0626     Document Type: Article

References (27)

1. Chung DW, Davie EW. γ and γ' chains of human fibrinogen are produced by alternative mRNA processing. Biochemistry 1984; 23: 4232-4236.
2. Fornace AJ Jr, Cummings DE, Comeau CM, et al. Structure of the human γ-fibrinogen gene. Alternate mRNA splicing near the 3' end of the gene produces γA and γB forms of γ-fibrinogen. J Biol Chem 1984; 259: 12826-12830.
3. Lovely RS, Falls LA, Al-Mondhiry HA, et al. Association of γA/γ' fibrinogen levels and coronary artery disease. Thromb Haemost 2002; 88: 26-31.
4. Mannila MN, Lovely RS, Kazmierczak SC, et al. Elevated plasma fibrinogen γ' concentration is associated with myocardial infarction: effects of variation in fibrinogen genes and environmental factors. J Thromb Haemost 2007; 5: 766-773.
5. Lovely RS, Kazmierczak SC, Massaro JM, et al. γ' fibrinogen: evaluation of a new assay for study of associations with cardiovascular disease. Clin Chem 2010; 56: 781-788.
6. Meh DA, Siebenlist KR, Mosesson MW. Identification and characterization of the thrombin binding sites on fibrin. J Biol Chem 1996; 271: 23121-5.
7. Lovely RS, Moaddel M, Farrell DH. Fibrinogen γ' chain binds thrombin exosite II. J Thromb Haemost 2003; 1: 124-131.
8. Pospisil CH, Stafford AR, Fredenburgh JC, et al. Evidence that both exosites on thrombin participate in its high affinity interaction with fibrin. J Biol Chem 2003; 278: 21584-21591.
9. Sabo TM, Farrell DH, Maurer MC. Conformational analysis of γ' peptide (410-427) interactions with thrombin anion binding exosite II. Biochemistry 2006; 45: 7434-7445.
10. Pineda AO, Chen ZW, Marino F, et al. Crystal structure of thrombin in complex with fibrinogen γ' peptide. Biophysical Chem 2007; 125: 556-559.
11. Falls LA, Farrell DH. Resistance of γA/γ' fibrin clots to fibrinolysis. J Biol Chem 1997; 272: 14251-14256.
12. Collet JP, Nagaswami C, Farrell DH, et al. Influence of γ' fibrinogen splice variant on fibrin physical properties and fibrinolysis rate. Arterioscler Thromb Vasc Biol 2004; 24: 382-386.
13. Cooper AV, Standeven KF, Ariëns RA. Fibrinogen γ-chain splice variant γ' alters fibrin formation and structure. Blood 2003; 102: 535-540.
14. Gersh KC, Nagaswami C, Weisel JW, et al. The presence of γ' chain impairs fibrin polymerization. Thromb Res 2009; 124: 356-363.
15. de Willige SU, Standeven KF, Philippou H, et al. The pleiotropic role of the fibrinogen γ' chain in hemostasis. Blood 2009; 114: 3994-4001.
16. Drouet L, Paolucci F, Pasqualini N, et al. Plasma γA/γ' fibrinogen ratio, a marker of arterial thrombotic activity: a new potential cardiovascular risk factor? Blood Coagul Fibrinolysis 1999; 10: S35-39.
17. Cheung EY, Uitte de Willige S, Vos HL, et al. Fibrinogen γ' in ischemic stroke: a case-control study. Stroke 2008; 39: 1033-1035.
18. Cheung EY, Vos HL, Kruip MJ, et al. Elevated fibrinogen γ' ratio is associated with cardiovascular diseases and acute phase reaction but not with clinical outcome. Blood 2009; 114: 4603-4604; author reply 4604-4605.
19. Beck JD, Couper DJ, Falkner KL, et al. The Periodontitis and Vascular Events (PAVE) pilot study: adverse events. J Periodontol 2008; 79: 90-96.
20. Couper DJ, Beck JD, Falkner KL, et al. The Periodontitis and Vascular Events (PAVE) pilot study: recruitment, retention, and community care controls. J Periodontol 2008; 79: 80-89.
21. Offenbacher S, Beck JD, Moss K, et al. Results from the Periodontitis and Vascular Events (PAVE) Study: a pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a secondary prevention model of cardiovascular disease. J Periodontol 2009; 80: 190-201.
22. Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003; 107: 363-369.
23. Beck JD, Offenbacher S. Relationships among clinical measures of periodontal disease and their associations with systemic markers. Ann Periodontol 2002; 7: 79-89.
24. Mosesson MW, Hernandez I, Raife TJ, et al. Plasma fibrinogen γ' chain content in the thrombotic microangiopathy syndrome. J Thromb Haemost 2007; 5: 62-69.
25. Uitte de Willige S, de Visser MC, Houwing-Duistermaat JJ, et al. Genetic variation in the fibrinogen γ gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen γ' levels. Blood 2005; 106: 4176-4183.
26. Uitte de Willige S, Rietveld IM, De Visser MC, et al. Polymorphism 10034C>T is located in a region regulating polyadenylation of FGG transcripts and influences the fibrinogen γ'/γA mRNA ratio. J Thromb Haemost 2007; 5: 1243-9.
27. de Willige SU, Pyle ME, Vos HL, et al. Fibrinogen γ gene 3'-end polymorphisms and risk of venous thromboembolism in the African-American and Caucasian population. Thromb Haemost 2009; 101: 1078-1084.