Efficacy of Virtual Reality Exposure Therapy in the Treatment of PTSD: A Systematic Review

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Gonçalves, Raquel ^a   Pedrozo, Ana Lúcia ^a   Coutinho, Evandro Silva Freire ^b   Figueira, Ivan ^a   Ventura, Paula ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BECK DEPRESSION INVENTORY; BRAIN REGION; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; CLINICAL GLOBAL IMPRESSION SCALE; CLINICIAN ADMINISTERED PTSD SCALE; COGNITIVE THERAPY; DAVIDSON TRAUMA SCALE; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE SEVERITY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; IMPACT OF EVENTS SCALE; IMPACT OF EVENTS SCALE REVISED; MALE; POSTTRAUMATIC COGNITION INVENTORY; POSTTRAUMATIC STRESS DISORDER; PSYCHOEDUCATION; PSYCHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC); RELAXATION TRAINING; REVIEW; SCORING SYSTEM; SUBJECTIVE UNIT OF DISCOMFORT SCALE; SYMPTOM CHECKLIST 90; SYSTEMATIC REVIEW; THERAPY EFFECT; TREATMENT DURATION; VIRTUAL REALITY EXPOSURE THERAPY;

HUMANS; STRESS DISORDERS, POST-TRAUMATIC; TREATMENT OUTCOME; VIRTUAL REALITY EXPOSURE THERAPY;

EID: 84871645856     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048469     Document Type: Review

References (32)

1. Brewin CR, Dalgleish T, Joseph S, (1996) A dual representation theory of post traumatic stress disorder. Psychological Review 103: 670-686.
2. Foa E, Kozac M, (1986) Emotional processing: exposure to corrective information. Psychological Bulletin 99: 20-35.
3. Foa E, Hembree E, Rothbaum B (2007) Prolonged Exposure Therapy for PTSD: Emotional Processing of Traumatic Experiences Therapist Guide. New York: Oxford University Press.
4. Schottenbauer MA, Glass DB, Arnkoff DB, Tendick AV, Gray SH, (2008) Nonresponse and Dropout Rates in Outcome Studies on PTSD: Review and Methodological Considerations. Psychiatry 71(2): 134-168.
5. Meyerbröker K, Emmelkamp PM, (2010) Virtual reality exposure therapy in anxiety disorders: A systematic review of process-and-outcomes studies. Depress Anxiety 27(10): 933-944.
6. Difede J, Hoffman H, Jaysinghe N, (2002) Innovative Use of Virtual Reality Technology in the Treatment of PTSD in the Aftermath of September 11. Psychiat Serv 53(9): 1083-1085.
7. Ready DJ, Pollack S, Rothbaum BO, Alarcon RD, (2006) Virtual reality exposure for veterans with posttraumatic stress disorder. J Aggression, Maltreatment, & Trauma 12: 199-220.
8. Rothbaum BO, Hodges L, Ready D, Graap K, Alarcon R, (2001) Virtual reality exposure therapy for Vietnam veterans with posttraumatic stress disorder. J Clin Psychiatr 62: 617-622.
9. Wald J, (2004) Efficacy of virtual reality exposure therapy for driving phobia: a multiple baseline across-subjects design. Behav Ther 35: 621-635.
10. Rothbaum BO, (2009) Using virtual reality to help our patients in the real world. Depress anxiety 26: 209-211.
11. Higgins J, Green S (2011) The Cochrane Collaboration's tool for assessing risk of bias in randomized trials. Version 5.1.0. Chapter 8: Assessing risk of bias in included studies. Available: http//www.cochrane-handbook.org. Accessed 2011 Sep 10.
12. Kocsis JH, Gerberb AJ, Milroda B, Roose SP, Barber J, et al. (2009) A new scale for assessing the quality of randomized clinical trials of psychotherapy. Comprehensive Psychiatry 51(3): 319-24.
13. Difede J, Cukor J, Jayasinghe N, Patt I, Jedel S, et al. (2007) Virtual reality exposure therapy for the treatment of posttraumatic stress disorder following September 11, 2001. J Clin Psychiatry 68(11): 1639-1647.
14. Wood D, Murphy J, McLay R, Koffman R, Spira J, et al. (2009) Cost effectiveness of virtual reality graded exposure therapy with physiological monitoring for the treatment of combat related posttraumatic stress disorder. Studies in Health Technology & Informatics 144(7): 223-229.
15. Ready DJ, Gerardi RJ, Backscheider AG, Mascaro N, Rothbaum BO, (2010) Comparing virtual reality exposure therapy to present-centered therapy with 11 U.S. Vietnam veterans with PTSD. Cyberpsychology, Behavior, and Social Network 13(1): 49-54.
16. Roy MJ, Francis J, Friedlander J, Banks-Williams L, Lande RG, et al. (2010) Improvement in cerebral function with treatment of posttraumatic stress disorder. Ann NY Acad Sci 1208: 142-149.
17. McLay RN, McBrian C, Wiederhold MD, Wiederhold BK, (2010) Exposure Therapy with and without Virtual Reality to Treat PTSD while in the Combat Theater: A Parallel Case Series. Cyberpsychology, Behavior, and Social Network 13(1): 37-42.
18. Rizzo AS, Difede J, Rothbaum BO, Reger G, Spitalnick J, et al. (2010) Development and early evaluation of the Virtual Iraq/Afghanistan exposure therapy system for combat related PTSD. Ann N Y Acad Sci 1208: 114-125.
19. Botella C, García-Palacios A, Guillen V, Baños RM, Quero S, et al. (2010) An Adaptive Display for the Treatment of Diverse Trauma PTSD Victims. Cyberpsychology, Behavior, and Social Networking 13(1): 67-71.
20. Gamito P, Oliveira J, Rosa P, Morais D, Duarte N, et al. (2010) PTSD Elderly War Veterans: A Clinical Controlled Pilot Study. Cyberpsychology, Behavior, and Social Networking 13(1): 43-48.
21. McLay RN, Wood DP, Webb-Murphy JA, Spira JL, Wiederhold MD, et al. (2011) A Randomized, Controlled Trial of Virtual Reality-Graded Exposure Therapy for Post- Traumatic Stress Disorder in Active Duty Service Members with Combat-Related Post- Traumatic Stress Disorder. Cyberpsychology, Behavior, and Social Network 14(4): 223-229.
22. Parsons T, Rizzo A, (2008) Affective outcomes of virtual reality exposure therapy for anxiety: A meta-analysis. J Behav Ther Exp Psychiatry 39: 250-261.
23. Powers M, Emmelkamp P, (2008) Virtual reality exposure therapy for anxiety disorders: a meta-analysis. Journal of Anxiety Disorders 22: 561-569.
24. Opris D, Pintea S, García-Palacios A, Botella C, Szamosközi S, et al. (2012) Virtual reality exposure therapy in anxiety disorders: a quantitative meta-analysis. Depression and Anxiety 29(2): 85-93.
25. Boutron I, Moher D, Douglas G, Schulz KF, Ravaud P, (2008) Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: Explanation and elaboration. Annals of Internal Medicine 148: 295-310.
26. Conner BT, (2010) When is the difference significant? Estimates of meaningfulnes in clinical research. Clin Psychol - Sci Pr 17(1): 52-57.
27. Shearer-Underhill C, Marker C, (2010) The use of the number needed to treat (NNT) in randomized clinical trials in psychological treatment. Clinical Psychology: Science and Practice 17: 41-47.
28. Seal KH, Maguem S, Cohen B, Gima KS, Metzler TJ, et al. (2010) VA Mental Health Services Utilization in Iraq and Afghanistan Veterans in the First Year of Receiving New Mental Health Diagnoses. Journal of Traumatic Stress 23(1): 5-16.
29. Erbes CR, Curry KT, Leskela J, (2009) Treatment Presentation and Adherence of Iraq/Afghanistan EraVeterans in Outpatient Care for Posttraumatic Stress Disorder. Psychological Services 6(3): 175-183.
30. Hoge CW, Castro CA, Messer SC, McGurk D, Cotting DI, et al. (2004) Combat Duty in Iraq and Afghanistan, Mental Health Problems, and Barriers to Care. The New England Journal of Medicine 351(1): 13-22.
31. Baños RM, Guillen V, Quero S, García-Palacios A, Alcaniz M, et al. (2011) A virtual reality system for the treatment of stress related disorders: A preliminary analysis of efficacy compared to a standard cognitive behavioral program. Int. J. Human-Computer Studies 69(9): 602-613.
32. Hembree E, Foa E, Dorfan N, Street G, Kowalski J, et al. (2003) Do patients drop out prematurely from exposure therapy for PTSD? J Trauma Stress 16(3): 555-562.