Functional assessment of four types of disintegrants and their effect on the spironolactone release properties

AAPS PharmSciTech

Volumn 13, Issue 4, 2012, Pages 1054-1062

  Rojas, John ^a   Guisao, Santiago ^a   Ruge, Vanesa ^a  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

Author keywords

disintegrant; dissolution studies; factorial experimental design; spironolactone

Indexed keywords

CROSCARMELLOSE SODIUM; CROSPOVIDONE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; SPIRONOLACTONE; STARCH GLYCOLATE SODIUM;

ARTICLE; DRUG EFFECT; DRUG FORMULATION; DRUG MECHANISM; DRUG RELEASE; DRUG SOLUBILITY; FACTORIAL DESIGN; PH; PRIORITY JOURNAL; TENSILE STRENGTH; WATER ABSORPTION; WATER TRANSPORT;

ABSORPTION; CARBOXYMETHYLCELLULOSE SODIUM; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; EXCIPIENTS; POVIDONE; SOLUBILITY; SPIRONOLACTONE; STARCH; TENSILE STRENGTH; WATER;

EID: 84871642493     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-012-9835-y     Document Type: Article

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