Neuroprotective effect of Erigeron Breviscapus (vant) Hand-mazz extract on retinal ganglion cells in rabbits with chronic elevated intraocular pressure

Asian Biomedicine

Volumn 5, Issue 2, 2011, Pages 195-203

  Zhong, Yi Sheng ^a   Xiang, Min Hong ^a   Ye, Wen ^b   Huang, Ping ^a   Cheng, Yu ^a   Jiang, You Qin ^c  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Chronic elevated IOP; Erigeron Breviscapus (Vant.) Hand Mazz extract; Neuroprotective effect; Rabbit; Retinal ganglion cells

Indexed keywords

ERIGERON BREVISCAPUS EXTRACT; METHYLCELLULOSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR EYE CHAMBER; ARTICLE; CELL DENSITY; CELL ORGANELLE; CELL STRUCTURE; CONTROLLED STUDY; DRUG EFFECT; ERIGERON; EXPERIMENTAL RABBIT; HISTOLOGY; INTRAOCULAR PRESSURE; MALE; MICROFILAMENT; MICROTUBULE; MITOCHONDRION; MYELIN SHEATH; NERVE FIBER DEGENERATION; NEUROPROTECTION; NONHUMAN; OPTIC DISK; OPTIC NERVE FIBER; RETINA GANGLION CELL; RETINA NERVE CELL; RIBOSOME; ROUGH ENDOPLASMIC RETICULUM; SMOOTH ENDOPLASMIC RETICULUM;

EID: 84871603368     PISSN: 19057415     EISSN: 1875855X     Source Type: Journal    
DOI: 10.5372/1905-7415.0502.025     Document Type: Article

References (33)

1. Anderson DR. Glaucoma: the damage caused by pressure. XLVI Edward Jackson memorial lecture. Am J Ophthalmol. 1989; 108:485-95. (Pubitemid 19280555)
2. Bathija R, Gupta N, Zangwill L, Weinreb RN. Changing definition of glaucoma. J Glaucoma. 1998; 7:165-9. (Pubitemid 28301624)
3. Foster PJ, Buhrmann R, Quigley HA, Johnson GJ. The definition and classification of glaucoma in prevalence surveys. Br J Ophthalmol. 2002; 86:238-42. (Pubitemid 34127552)
4. Palmberg P. Risk factors for glaucoma progression: Where does intraocular pressure fit in? Arch Ophthalmol. 2001; 119: 897-8. (Pubitemid 32530320)
5. Leske MC, Heijl A, Hussein M, Bengtsson B, Hyman L, Komaroff E. Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trail. Arch Ophthalmol. 2003; 121:48-56. (Pubitemid 36401765)
6. Collaborative Normal-Tension Glaucoma Study Group. The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. Am J Ophthalmol. 1998; 126:498-505.
7. The AIGS investigators. Advanced glaucoma intervention study: 7. the relationship between control of intraocular pressure and visual field deterioration. Am J Ophthalmol. 2000; 130:429-40.
8. Gao M, Gu M, Liu CZ. Two-step purification of scutellarin from Erigeron breviscapus (vant.) Hand. Mazz. by high-speed counter-current chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2006; n838:139-43. (Pubitemid 43946745)
9. Zhou QS, Zhao YM, Bai X, Li PX, Ruan CG. Effect of new-breviscapine on fibrinolysis and anticoagulation of human vascular endothelial cells (in Chinese). Zhongguo Yao Li Xue Bao. 1992; 13:239-242.
10. Wang ZY, Chen DC, He Y, Ruan CG, Zhang RW. Differential effects of new breviscapine on arachidonic acid metabolisms in blood cells and endothelial cells (in Chinese). Zhongguo Yao Li Xue Bao. 1993; 14:148-151. (Pubitemid 23113974)
11. Wang NL, Sun XH, Li JZ, Wang JH, Chen XM, Lin D, et al. Neuroprotective effects of erigeron breviscapus (vant) hand-mazz on glaucoma- A multi-center clinical trail. Int J Ophthalmol. 2004;4:587-92.
12. Jiang YQ, Wu ZZ, Mo XJ, Chen XM, Jiang YL. An approach treat the late stage glaucoma with intraocular pressure controlled after trebecuculectomy. Chin Ophthalmic Res. 1991; 9:229-32.
13. Jia L, Liu Z, Luo X, Jiang Y, Wu Z, Liu D. The effect of Qing Guang Kang on the metabolism of retinal ganglion cells of rats after artificial acute high intraocular pressure (in Chinese). Zhonghua Yan Ke Za Zhi. 1995; 31:129-31.
14. Zhu Y, Jiang Y, Liu Z, Luo X, Wu Z. The affect of Erigeron Breviscapus (Vant.) Hand-Mazz on axoplasmic transport of optic nerve in rats with experimentally elevated intraocular pressure (in Chinese). Zhonghua Yan Ke Za Zhi. 2000; 36:289-91.
15. Manni G, Lambiase A, Centofanti M, Mattei E, De Gregorio A, Aloe L, et al. Histopathological evaluation of retinal damage during intraocular hypertension in rabbit: involvement of ganglion cells and nerve fiber layer. Graefes Arch Clin Exp Ophthalmol. 1996; 234 (Suppl 1):S209-13.
16. Zhu MD, Cai FY. Development of experimental chronic intraocular hypertension in the rabbit. Aust N Z Ophthalmol. 1992; 20:225-34. (Pubitemid 23197650)
17. Heijl A, Leske MC, Bengtsson B, Hyman L, Bengtsson B, Hussein M, et al. Reduction of intraocular pressure and glaucoma progression: results from the early manifest glaucoma trial. Arch Ophthalmol. 2002; 120:1268-79. (Pubitemid 36105431)
18. Collaborative Normal-Tension Glaucoma Study Group. The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma: Collaborative Normal-Tension Glaucoma Study Group. Am J Ophthalmol. 1998; 126:498-505.
19. Collaborative Normal-Tension Glaucoma Study Group. Comparison of glaucomatous progression between untreated patients with normal tension glaucoma and patients with therapeutically reduced intraocular pressure: Collaborative Normal-Tension Glaucoma Study Group. Am J Ophthalmol. 1998; 126:487-97.
20. Quigley HA, McKinnon SJ, Zack DJ, et al. Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Invest Ophthamol Vis Sci 2000; 41:3460-3466.
21. Pease ME, McKinnon SJ, Quigley HA, Kerrigan- Baumrind LA, Zack DJ. Obstructed axonal transport of BDNF and its receptor TRKB in experimental glaucoma. Invest Ophthamol Vis Sci. 2000; 41:764-74. (Pubitemid 30158887)
22. Vorwerk CK, Gorla MS, Dreyer EB. An experimental basis for implicating excitotoxicity in glaucomatous optic neuropathy. Surv Ophthalmol 1999; 43(Suppl 1):S142-50. (Pubitemid 29328589)
23. Dreyer EB, Zurakowski D, Schumer RA, Podos SM, Lipton SA. Elevated glutamate levels in the vitrous body of humans and monkeys with glaucoma. Arch Ophthalmol. 1996; 114:299-305. (Pubitemid 26086736)
24. Vorwerk CK, Lipton SA, Zurakowski D, Hyman BT, Sabel BA, Dreyer EB. Chronic low-dose glutamate is toxic to retinal ganglion cells: toxicity blocked by memantine. Invest Ophthamol Vis Sci. 1996; 37:1618-24. (Pubitemid 26271413)
25. Flammer J, Orgul S, Costa VP, Orzalesi N, Krieglstein GK, Serra LM, et al. The impact of ocular blood flow in glaucoma. Prog Retin Eye Res. 2002; 21:359-93. (Pubitemid 34879080)
26. Hayreh SS. The blood supply of the optic nerve head and the evaluation of it-myth and reality. Prog Retin Eye Res. 2001; 20:563-93. (Pubitemid 32695342)
27. Tielsch JM, Katz J, Sommer A, Quigley HA, Javitt JC. Hypertension, perfusion pressure, and primary openangle glaucoma: a population-based assessment. Arch Ophthalmol. 1995; 113:216-21.
28. Zhang RW, Yang SY, Lin YY. Studies on chemical constituents of dengzhanhua (Erigeron breviscapus (Vant.) Hand-Mazz). I. The isolation and identification of pyromeconic acid and a new glucoside (in Chinese). Yao Xue Xue Bao. 1981; 16:68-9.
29. Zhang WD, Chen WS, Wang YH, Liu WY, Kong DY, Li HT. Studies on flavone constituents of Erigeron breviscapus (Vant.) Hand.-Mazz (in Chinese). Zhongguo Zhong Yao Za Zhi. 2000; 25:536-8.
30. Zhang WD, Ha TB, Chen WS, Kong DY, Li HT, Wang YH, et al. Study on the structure and activity of new phenolic acid compounds from Erigeron breviscapus (in Chinese). Yao Xue Xue Bao. 2001; 36:360-3.
31. Zhang WD, Chen WS, Wang YH, Liu WY, Kong DY, Li HT. Two new glycosides from Erigeron breviscapus (Vant.) Hand.-Mazz. Zhongguo (in Chinese). Zhong Yao Za Zhi 2001; 26:689-90.
32. Chu Q, Wu T, Fu L, Ye J. Simultaneous determination of active ingredients in Erigeron breviscapus (Vant.) Hand-Mazz. By capillary electrophoresis with electrochemical detection. J Pharm Biomed Anal. 2005; 37: 535-41. (Pubitemid 40312299)
33. Bastianetto S, Zheng WH, Quirion R. The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase C. J Neurochem. 2000; 74:2268-77. (Pubitemid 30314201)