Heat stabilization of blood spot samples for determination of metabolically unstable drug compounds

Bioanalysis

Volumn 5, Issue 1, 2013, Pages 31-39

  Blessborn, Daniel ^a,b   Sköld, Karl ^c   Zeeberg, David ^c   Kaewkhao, Karnrawee ^a   Sköld, Olof ^c   Ahnoff, Martin ^c,d,e  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Denator AB   (Sweden)

^d ASTRAZENECA R AND D   (Sweden)

^e UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; ARTEMETHER; CEFOTAXIME; DIHYDROARTEMISININ; OSELTAMIVIR; RIBAVIRIN;

ANALYTIC METHOD; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRIED BLOOD SPOT TESTING; DRUG DEGRADATION; DRUG DETERMINATION; DRUG STABILITY; DRUG STRUCTURE; HEAT STABILIZATION; HEAT TREATMENT; HIGH TEMPERATURE PROCEDURES; TEMPERATURE SENSITIVITY;

AMODIAQUINE; ANALYTIC SAMPLE PREPARATION METHODS; ARTEMISININS; BUTYRYLCHOLINESTERASE; CEFOTAXIME; DRIED BLOOD SPOT TESTING; DRUG STABILITY; HOT TEMPERATURE; HUMANS; OSELTAMIVIR; PHARMACEUTICAL PREPARATIONS;

EID: 84871586789     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.294     Document Type: Article

References (22)

1. Michopoulos F, Theodoridis G, Smith CJ, Wilson ID. Metabolite profiles from dried blood spots for metabonomic studies using UPLC combined with orthogonal acceleration ToFYMS: Effects of different papers and sample storage stability. Bioanalysis 3(24), 2757-2767 (2011).
2. Dell D. Labile metabolites. Chromatographia 59(0), S139-S148 (2004).
3. Cossum PA. Role of the red blood cell in drug metabolism. Biopharm. Drug Dispos. 9(4), 321-336 (1988).
4. Chen J, Hsieh Y. Stabilizing drug molecules in biological samples. Ther. Drug Monit. 27(5), 617-624 (2005).
5. Holm G, Kylberg-Hanssen K, Svensson L. Use of dodecyl sulfate as an esterase inhibitor before gas-chromatographic determination of labile beta-adrenoceptor blocking drugs. Clin. Chem. 31(6), 868-870 (1985).
6. Fakt C, Stenhoff H. Determination of an ultrashort-acting antihypertensive dihydropyridine, clevidipine, in blood using capillary gas chromatographyYmass spectrometry and of the primary metabolite using liquid chromatography and fluorescence detection. J. Chromatogr. B Biomed. Sci. Appl. 723(1-2), 211-219 (1999).
7. Zheng N, Fung EN, Buzescu A, Arnold ME, Zeng J. Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: Potential contributors to the matrix effects on bioanalysis by liquid chromatography/ tandem mass spectrometry. Rapid Commun. Mass Spectrom. 26(11), 1291-1304 (2012).
8. Lindegardh N, Davies GR, Hien TT et al. Importance of collection tube during clinical studies of oseltamivir. Antimicrob. Agents Chemother. 51(5), 1835-1836 (2007).
9. Lindegardh N, Davies GR, Tran TH et al. Rapid degradation of oseltamivir phosphate in clinical samples by plasma esterases. Antimicrob. Agents Chemother. 50(9), 3197-3199 (2006).
10. Smejkal GB, Rivas-Morello C, Chang JH et al. Thermal stabilization of tissues and the preservation of protein phosphorylation states for two-dimensional gel electrophoresis. Electrophoresis 32(16), 2206-2215 (2011).
11. Strnadova KA, Holub M, Muhl A et al. Long-term stability of amino acids and acylcarnitines in dried blood spots. Clin. Chem. 53(4), 717-722 (2007).
12. Liu G, Ji QC, Jemal M, Tymiak AA, Arnold ME. Approach to evaluating dried blood spot sample stability during drying process and discovery of a treated card to maintain analyte stability by rapid on-card pH modification. Anal. Chem. 83(23), 9033-9038 (2011).
13. Svensson M, Boren M, Skold K et al. Heat stabilization of the tissue proteome: A new technology for improved proteomics. J. Proteome Res. 8(2), 974-981 (2009).
14. Kultima K, Skold K, Boren M. Biomarkers of disease and post-mortem changes Y heat stabilization, a necessary tool for measurement of protein regulation. J. Proteomics 75(1), 145-159 (2011).
15. Hooff GP, Meesters RJ, Van Kampen JJ et al. Dried blood spot UHPLCYMS/MS analysis of oseltamivir and oseltamivircarboxylate Y a validated assay for the clinic. Anal. Bioanal. Chem. 400(10), 3473-3479 (2011).
16. Lindegardh N, Hanpithakpong W, Kamanikom B et al. Quantification of dihydroartemisinin, artesunate and artemisinin in human blood: Overcoming the technical challenge of protecting the peroxide bridge. Bioanalysis 3(14), 1613-1624 (2011).
17. Gitau EN, Muchohi SN, Ogutu BR, Githiga IM, Kokwaro GO. Selective and sensitive liquid chromatographic assay of amodiaquine and desethylamodiaquine in whole blood spotted on filter paper. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 799(1), 173-177 (2004).
18. Welch WD, Bawdon RE. Cefotaxime metabolism by hemolyzed blood: Quantitation and inhibition of the deacetylation reaction. Diagn. Microbiol. Infect. Dis. 4(2), 119-124 (1986).
19. Minzi OM, Rais M, Svensson JO, Gustafsson LL, Ericsson O. High-performance liquid chromatographic method for determination of amodiaquine, chloroquine and their monodesethyl metabolites in biological samples. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 783(2), 473-480 (2003).
20. White S, Calver BL, Newsway V et al. Enzymes of drug metabolism during delirium. Age Ageing 34(6), 603-608 (2005).
21. Lindegardh N, Hanpithakpong W, Wattanagoon Y, Singhasivanon P, White NJ, Day NP. Development and validation of a liquid chromatographicYtandem mass spectrometric method for determination of oseltamivir and its metabolite oseltamivir carboxylate in plasma, saliva and urine. J. Chromatogr. 859(1), 74-83 (2007).
22. Lindegardh N, Forslund M, Green MD, Kaneko A, Bergqvist Y. Automated solid-phase extraction for determination of amodiaquine, chloroquine and metabolites in capillary blood on sampling paper by liquid chromatography. Chromatographia 55(1), 5-12 (2002).