Approach to evaluating dried blood spot sample stability during drying process and discovery of a treated card to maintain analyte stability by rapid on-card pH modification

Analytical Chemistry

Volumn 83, Issue 23, 2011, Pages 9033-9038

  Liu, Guowen ^a   Ji, Qin C ^a   Jemal, Mohammed ^a   Tymiak, Adrienne A ^a   Arnold, Mark E ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTES; BIOANALYSIS; BIOANALYTICAL METHODS; BLOOD SAMPLES; DRIED BLOOD SPOTS; DRUG CANDIDATES; DRYING PROCESS; GENERIC APPROACH; HUMAN BLOODS; PH MODIFICATION; ROOM TEMPERATURE; SAMPLE COLLECTION; SAMPLE PROCESSING; STABILITY EVALUATION; STORAGE STABILITY; VIABLE SOLUTIONS;

BLOOD; DEGRADATION; RATING; STABILITY;

DRYING;

CITRIC ACID; DELCASERTIB; PEPTIDE;

ARTICLE; BLOOD; CHEMISTRY; DRIED BLOOD SPOT TESTING; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PH; TANDEM MASS SPECTROMETRY; TEMPERATURE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CITRIC ACID; DRIED BLOOD SPOT TESTING; DRUG STABILITY; HUMANS; HYDROGEN-ION CONCENTRATION; PEPTIDES; TANDEM MASS SPECTROMETRY; TEMPERATURE;

EID: 82555168071     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac2023876     Document Type: Article

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