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Volumn 13, Issue 1, 2013, Pages 5-7

Assessment of regulatory T-cell function in forthcoming clinical trials of cell therapy

Author keywords

CD154; CD69; CFSE; FOXP3 protein; human; regulatory T cells

Indexed keywords

CYTOKINE;

EID: 84871586465     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/erm.12.133     Document Type: Review
Times cited : (4)

References (20)
  • 2
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • Bennett CL, Christie J, Ramsdell F et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27(1), 20-21 (2001).
    • (2001) Nat. Genet , vol.27 , Issue.1 , pp. 20-21
    • Bennett, C.L.1    Christie, J.2    Ramsdell, F.3
  • 4
    • 79956258982 scopus 로고    scopus 로고
    • Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity
    • Hippen KL, Merkel SC, Schirm DK et al. Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity. Sci. Transl. Med. 3(83), 83ra41 (2011).
    • (2011) Sci. Transl. Med , vol.3 , Issue.83
    • Hippen, K.L.1    Merkel, S.C.2    Schirm, D.K.3
  • 5
    • 79251589897 scopus 로고    scopus 로고
    • Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells
    • Golovina TN, Mikheeva T, Brusko TM, Blazar BR, Bluestone JA, Riley JL. Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells. PLoS ONE 6(1), e15868 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.1
    • Golovina, T.N.1    Mikheeva, T.2    Brusko, T.M.3    Blazar, B.R.4    Bluestone, J.A.5    Riley, J.L.6
  • 6
    • 78650835204 scopus 로고    scopus 로고
    • Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model
    • Issa F, Hester J, Goto R, Nadig SN, Goodacre TE, Wood K. Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized mouse model. Transplantation 90(12), 1321-1327 (2010).
    • (2010) Transplantation , vol.90 , Issue.12 , pp. 1321-1327
    • Issa, F.1    Hester, J.2    Goto, R.3    Nadig, S.N.4    Goodacre, T.E.5    Wood, K.6
  • 7
    • 79956288367 scopus 로고    scopus 로고
    • Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells
    • Sagoo P, Ali N, Garg G, Nestle FO, Lechler RI, Lombardi G. Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells. Sci. Transl. Med. 3(83), 83ra42 (2011).
    • (2011) Sci. Transl. Med , vol.3 , Issue.83
    • Sagoo, P.1    Ali, N.2    Garg, G.3    Nestle, F.O.4    Lechler, R.I.5    Lombardi, G.6
  • 8
    • 77954539326 scopus 로고    scopus 로고
    • In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells
    • Nadig SN, Wieckiewicz J, Wu DC et al. In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells. Nat. Med. 16(7), 809-813 (2010).
    • (2010) Nat. Med , vol.16 , Issue.7 , pp. 809-813
    • Nadig, S.N.1    Wieckiewicz, J.2    Wu, D.C.3
  • 9
    • 70249122695 scopus 로고    scopus 로고
    • First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127? T regulatory cells
    • Trzonkowski P, Bieniaszewska M, Juscinska J et al. First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127? T regulatory cells. Clin. Immunol. 133(1), 22-26 (2009).
    • (2009) Clin. Immunol , vol.133 , Issue.1 , pp. 22-26
    • Trzonkowski, P.1    Bieniaszewska, M.2    Juscinska, J.3
  • 10
    • 78751696183 scopus 로고    scopus 로고
    • Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics
    • Brunstein CG, Miller JS, Cao Q et al. Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics. Blood 117(3), 1061-1070 (2011).
    • (2011) Blood , vol.117 , Issue.3 , pp. 1061-1070
    • Brunstein, C.G.1    Miller, J.S.2    Cao, Q.3
  • 11
    • 79953809817 scopus 로고    scopus 로고
    • Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
    • Di Ianni M, Falzetti F, Carotti A et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood 117(14), 3921-3928 (2011).
    • (2011) Blood , vol.117 , Issue.14 , pp. 3921-3928
    • Di Ianni, M.1    Falzetti, F.2    Carotti, A.3
  • 12
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi T, Kuniyasu Y, Toda M et al. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10(12), 1969-1980 (1998).
    • (1998) Int. Immunol , vol.10 , Issue.12 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3
  • 13
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T-cell activation in vitro by inhibiting interleukin 2 production
    • Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T-cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188(2), 287-296 (1998).
    • (1998) J. Exp. Med , vol.188 , Issue.2 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 14
    • 0032739331 scopus 로고    scopus 로고
    • Quantitative analysis of lymphocyte differentiation and proliferation in vitro using carboxyfluorescein diacetate succinimidyl ester
    • Hasbold J, Gett AV, Rush JS et al. Quantitative analysis of lymphocyte differentiation and proliferation in vitro using carboxyfluorescein diacetate succinimidyl ester. Immunol. Cell Biol. 77(6), 516-522 (1999).
    • (1999) Immunol. Cell Biol , vol.77 , Issue.6 , pp. 516-522
    • Hasbold, J.1    Gett, A.V.2    Rush, J.S.3
  • 15
    • 66949171924 scopus 로고    scopus 로고
    • Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor
    • Miyara M, Yoshioka Y, Kitoh A et al. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity 30(6), 899-911 (2009).
    • (2009) Immunity , vol.30 , Issue.6 , pp. 899-911
    • Miyara, M.1    Yoshioka, Y.2    Kitoh, A.3
  • 16
    • 84857565392 scopus 로고    scopus 로고
    • A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy
    • Canavan JB, Afzali B, Scott?C et al. A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy. Blood 119(8), e57-e66 (2012).
    • (2012) Blood , vol.119 , Issue.8
    • Canavan, J.B.1    Afzali, B.2    Scott, C.3
  • 18
    • 27144557584 scopus 로고    scopus 로고
    • A live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profiles
    • Chattopadhyay PK, Yu J, Roederer M. A live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profiles. Nat. Med. 11(10), 1113-1117 (2005).
    • (2005) Nat. Med , vol.11 , Issue.10 , pp. 1113-1117
    • Chattopadhyay, P.K.1    Yu, J.2    Roederer, M.3
  • 19
    • 81155151462 scopus 로고    scopus 로고
    • Isolation strategies of regulatory T cells for clinical trials: Phenotype, function, stability, and expansion capacity
    • Ukena SN, H?ting M, Velaga S et al. Isolation strategies of regulatory T cells for clinical trials: phenotype, function, stability, and expansion capacity. Exp. Hematol. 39(12), 1152-1160 (2011).
    • (2011) Exp. Hematol , vol.39 , Issue.12 , pp. 1152-1160
    • Ukena, S.N.1    Hting, M.2    Velaga, S.3
  • 20
    • 72949119542 scopus 로고    scopus 로고
    • Translational mini-review series on Th17 cells: Induction of interleukin-17 production by regulatory T cells
    • Afzali B, Mitchell P, Lechler RI, John S, Lombardi G. Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells. Clin. Exp. Immunol. 159(2), 120-130 (2010).
    • (2010) Clin. Exp. Immunol , vol.159 , Issue.2 , pp. 120-130
    • Afzali, B.1    Mitchell, P.2    Lechler, R.I.3    John, S.4    Lombardi, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.