Activation of phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling and the consequent induction of transformation by overexpressed 14-3-3γ protein require specific amino acids within 14-3-3γN-terminal variable region II

Journal of Biological Chemistry

Volumn 287, Issue 52, 2012, Pages 43300-43311

  Radhakrishnan, Vijayababu M ^a   Putnam, Charles W ^a   Martinez, Jesse D ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

14-3-3 PROTEINS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELLULAR FUNCTION; CHIMERIC PROTEINS; HUMAN ISOFORMS; ISOFORMS; MAPK SIGNALING; MITOGEN ACTIVATED PROTEIN KINASE; N-TERMINALS; ONCOGENESIS; PHOSPHATIDYLINOSITOL 3-KINASE; SECONDARY STRUCTURES; SOFT AGAR; TUMOR SUPPRESSORS;

BIOINFORMATICS; PLANTS (BOTANY); PROTEINS; TUMORS;

AMINO ACIDS;

14 3 3 GAMMA PROTEIN; AMINO ACID; CHIMERIC PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN 14 3 3; STRATIFIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; BIOINFORMATICS; BIOLOGICAL ACTIVITY; CELL LYSATE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

14-3-3 PROTEINS; AMINO ACID SUBSTITUTION; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; MUTATION, MISSENSE; NIH 3T3 CELLS; ONCOGENE PROTEINS; PEPTIDE MAPPING; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS;

EUKARYOTA;

EID: 84871576784     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.397877     Document Type: Article

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