Elevated intracellular levels of iron in host cells promotes Burkholderia pseudomallei infection

Asian Biomedicine

Volumn 6, Issue 3, 2012, Pages 465-471

  Amornrit, Warisa ^a   Muangsombut, Veerachat ^a   Wangteeraprasert, Tanapol ^a   Korbsrisate, Sunee ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Burkholderia pseudomallei; Intracellular survival; Invasion; Iron elevation; Virulence

Indexed keywords

ASCORBIC ACID; FERROUS SULFATE; IRON;

ARTICLE; BACTERIAL VIRULENCE; BURKHOLDERIA PSEUDOMALLEI; CELL INVASION; CELL SURVIVAL; CONTROLLED STUDY; GIANT CELL; HELA CELL; HOST CELL; MELIOIDOSIS; MONOLAYER CULTURE; NONHUMAN; PHENOTYPE; PLAQUE FORMING CELL;

EID: 84871576439     PISSN: 19057415     EISSN: 1875855X     Source Type: Journal    
DOI: 10.5372/1905-7415.0603.078     Document Type: Article

References (24)

1. Weiss G. Iron and immunity: A double-edged sword. Eur J Clin Invest. 2002; 32 (Suppl 1):70-8. (Pubitemid 41704991)
2. Puntarulo S. Iron, oxidative stress and human health. Mol Aspects Med. 2005; 26:299-312. (Pubitemid 41225354)
3. Lawrence TH, Biggers CJ, Simonton PR. Bacteriostatic inhibition of Klebsiella pneumoniae by three human transferrins. Ann Hum Biol. 1977; 4:281-4. (Pubitemid 8145225)
4. Reiter B, Brock JH, Steel ED. Inhibition of Escherichia coli by bovine colostrum and post-colostral milk. II. The bacteriostatic effect of lactoferrin on a serum susceptible and serum resistant strain of E. coli. Immunology. 1975; 28: 83-95.
5. Ganz T. Hepcidin-a peptide hormone at the interface of innate immunity and iron metabolism. Curr Top Microbiol Immunol. 2006; 306:183-98. (Pubitemid 47400322)
6. Khan FA, Fisher MA, Khakoo RA. Association of hemochromatosis with infectious diseases: Expanding spectrum. Int J Infect Dis. 2007; 11:482-7. (Pubitemid 47626050)
7. Foster SL, Richardson SH, Failla ML. Elevated iron status increases bacterial invasion and survival and alters cytokine/chemokine mRNA expression in Caco-2 human intestinal cells. J Nutr. 2001; 131:1452-8. (Pubitemid 32422966)
8. Bullen JJ, Ward CG, Wallis SN. Virulence and the role of iron in Pseudomonas aeruginosa infection. Infect Immun. 1974; 10:443-50.
9. Wuthiekanun V, Smith MD, Dance DA, White NJ. Isolation of Pseudomonas pseudomallei from soil in north-eastern Thailand. Trans R Soc Trop Med Hyg. 1995; 89:41-3.
10. Schaible UE, Kaufmann SH. Iron and microbial infection. Nat Rev Microbiol. 2004; 2:946-53. (Pubitemid 39562533)
11. Loprasert S, Sallabhan R, Whangsuk W, Mongkolsuk S. Characterization and mutagenesis of fur gene from Burkholderia pseudomallei. Gene. 2000; 254:129-37.
12. Tuanyok A, Kim HS, Nierman WC, Yu Y, Dunbar J, Moore RA, et al. Genome-wide expression analysis of iron regulation in Burkholderia pseudomallei and Burkholderia mallei using DNA microarrays. FEMS Microbiol Lett. 2005; 252:327-35. (Pubitemid 41531660)
13. Wanachiwanawin W. Infections in E-beta thalassemia. J Pediatr Hematol Oncol. 2000; 22:581-7.
14. Pierre JL, Fontecave M. Iron and activated oxygen species in biology: The basic chemistry. Biometals. 1999; 12:195-9. (Pubitemid 29481363)
15. Muangsombut V, Suparak S, Pumirat P, Damnin S, Vattanaviboon P, Thongboonkerd V, et al. Inactivation of Burkholderia pseudomallei bsaQ results in decreased invasion efficiency and delayed escape of bacteria from endocytic vesicles. Arch Microbiol. 2008; 190:623-31.
16. Suparak S, Kespichayawattana W, Haque A, Easton A, Damnin S, Lertmemongkolchai G, et al. Multinucleated giant cell formation and apoptosis in infected host cells is mediated by Burkholderia pseudomallei type III secretion protein BipB. J Bacteriol. 2005; 187:6556-60. (Pubitemid 41318415)
17. Draper AD, Mayo M, Harrington G, Karp D, Yinfoo D, Ward L, et al. Association of the melioidosis agent Burkholderia pseudomallei with water parameters in rural water supplies in northern Australia. Appl Environ Microbiol. 2010; 76:5305-7.
18. Wong KT, Puthucheary SD, Vadivelu J. The histopathology of human melioidosis. Histopathology. 1995; 26:51-5.
19. Moalem S, Weinberg ED, Percy ME. Hemochromatosis and the enigma of misplaced iron: Implications for infectious disease and survival. Biometals. 2004; 17:135-9. (Pubitemid 38406386)
20. Rawat R, Humphrey J, Ntozini R, Mutasa K, Iliff P, Stoltzfus R. Elevated iron stores are associated with HIV disease severity and mortality among postpartum women in Zimbabwe. Public Health Nutr. 2009; 12:1321-9.
21. Ozment CP, Turi JL. Iron overload following red blood cell transfusion and its impact on disease severity. Biochim Biophys Acta. 2009; 1790:694-701
22. Pieracci FM, Barie PS. Iron and the risk of infection. Surg Infect (Larchmt). 2005; 6 Suppl 1:S41-46.
23. Suputtamongkol Y, Chaowagul W, Chetchotisakd P, Lertpatanasuwun N, Intaranongpai S, Ruchutrakool T, et al. Risk factors for melioidosis and bacteremic melioidosis. Clin Infect Dis. 1999; 29:408-13. (Pubitemid 29380208)
24. Banin E, Lozinski A, Brady KM, Berenshtein E, Butterfield PW, Moshe M, et al. The potential of desferrioxamine-gallium as an anti-pseudomonas therapeutic agent. Proc Natl Acad Sci USA. 2008; 105:16761-6.