Mapping QTL for growth and muscling traits in three connected porcine F2 crosses

Archiv fur Tierzucht

Volumn 55, Issue 6, 2012, Pages 577-589

  Rückert, Christine ^a   Stratz, Patrick ^a   Preuss, Siegfried ^a   Bennewitz, Jörn ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Growth and muscling traits; Joint analysis; QTL

Indexed keywords

ANIMALIA; SUIDAE; SUS; SUS SCROFA;

EID: 84871564420     PISSN: 00039438     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Andersson L, Haley CS, Ellegren H, Knott SA, Johansson M, Andersson K, Andersson-Eklund L, Edfors-Lilja I, Fredholm M, Hansson I, Håkansson J, Lundström K (1994) Genetic mapping of quantitative trait loci for growth and fatness in pigs. Science 263, 1771-1774
2. Bang ML, Mudry RE, McElhinny AS, Trombitás K, Geach AJ, Yamasaki R, Sorimachi H, Granzier H, Gregorio CC, Labeit S (2001) Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies. J Cell Biol 153, 413-428
3. Bennewitz J, Reinsch N, Grohs C, Levéziel H, Malafosse A, Thomsen H, Xu N, Looft C, Kühn C, Brockmann GA, Schwerin M, Weimann C, Hiendleder S, Erhardt G, Medjugorac I, Russ I, Förster M, Brenig B, Reinhardt F, Reents R, Averdunk G, Blümel J, Boichard D, Kalm E (2003) Combined analysis of data from two granddaughter designs: A simple strategy for QTL confirmation and increasing experimental power in dairy cattle. Genet Sel Evol 35, 319-338
4. Bennewitz J, Meuwissen THE (2010) The distribution of QTL additive and dominance effects in porcine F2 crosses. J Anim Breed Genet 127, 171-179
5. Bidanel JP, Milan D, Iannuccelli N, Amigues Y, Boscher MY, Bourgeois F, Caritez JC, Gruand J, Le Roy P, Lagant H, Quintanilla R, Renard C, Gellin J, Ollivier L, Chevalet C (2001) Detection of quantitative trait loci for growth and fatness in pigs. Genet Sel Evol 33, 289-309
6. Davoli R, Braglia S, Lama B, Fontanesi L, Buttazzoni L, Baiocco C, Russo V (2003) Mapping, identification of polymorphisms and analysis of allele frequencies in the porcine skeletal muscle myopalladin and titin genes. Cytogenet Genome Res 102, 152-156
7. Del Sal G, Collavin L, Ruaro ME, Edomi P, Saccone S, Valle GD, Schneider C (1994) Structure, function, and chromosome mapping of the growth-suppressing human homologue of the murine gas1 gene. Proc Natl Acad Sci 91, 1848-1852
8. Demars J, Riquet J, Sanchez MP, Billon Y, Hocquette JF, Lebret B, Iannuccelli N, Bidanel JP, Milan D, Gondret F (2007) Metabolic and histochemical characteristics of fat and muscle tissues in homozygous or heterozygous pigs for the body composition QTL located an chromosome 7. Physiol Genomics 30, 232-241
9. Fan B, Du ZQ, Rothschild MF (2009) The fat mass and obesity-associated (FTO) gene is associated with intramuscular fat content and growth rate in the pig. Anim Biotechnol 20, 58-70
10. Fan B, Onteru SK, Du ZQ, Garrick DJ, Stalder KJ, Rothschild MF (2011) Genome-wide association study identifies loci for body composition and structural soundness traits in pigs. PLoS ONE 6, e14726. doi:10.1371/journal. pone.0014726
11. Geldermann H, Müller E, Moser G, Reiner G, Bartenschlager H, Cepica S, Stratil A, Kuryl J, Moran C, Davoli R, Brunsch C (2003) Genome-wide linkage and QTL mapping in porcine F2 families generated from Pietrain, Meishan and Wild Boar crosses. J Anim Breed Genet 120, 363-393
12. Hu ZL, Dracheva S, Jang W, Maglott D, Bastiaansen J, Rothschild MF, Reecy JM (2005) A QTL resource and comparison tool for pigs: PigQTLDB. Mammalian Genome 16, 792-800
13. Jeon JT, Carlborg Ö, Törnsten A, Giuffra E, Amarger V, Chardon P, Andersson-Eklund L, Andersson K, Hansson I, Lundström K, Andersson L (1999) A paternally expressed QTL affecting skeletal and cardiac muscle mass in pigs maps to the IGF2 locus. Nat Genet 21, 157-158
14. Jiang AA, Li MZ, Zhang K, Gu YR, Li XW (2011) Expression changes of PPARGC1A during the development of Lean and Obese pigs. J Anim Vet Adv 10, 597-600
15. Kaur P, Reis MD, Couchman GR, Forjuoh SN, Greene JF, Asea A (2010) SERPINE1 links obesity and diabetes: a pilot study. J Proteomics Bioinform 3, 191-199
16. Kingsley DM, Bland AE, Grubber JM, Marker PC, Russell LB, Copeland NG, Jenkins NA (1992) The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF β superfamily. Cell 71, 399-410
17. Lynch M, Walsh B (1998) Genetics and Analysis of Quantitative Traits. Sunderland, Mass., USA
18. Milan D, Bidanel JP, Iannuccelli N, Riquet J, Amigues Y, Gruand J, Le Roy P, Renard C, Chevalet C (2002) Detection of quantitative trait loci for carcass composition traits in pigs. Genet Sel Evol 34, 705-728
19. Nezer C, Moreau L, Brouwers B, Coppieters W, Detilleux J, Hanset R, Karim L, Kvasz A, Leroy P and Georges M (1999) An imprinted QTL with major effect on muscle mass and fat deposition maps to the IGF2 locus in pigs. Nat Genet 21, 155-156
20. Piepho HP (2001) A quick method for computing approximate thresholds for quantitative trait loci detection. Genetics 157, 425-432
21. Reinsch N (1999) A multiple-species, multiple-project database for genotypes at codominant loci. J Anim Breed Genet 116, 425-435
22. Ren J, Duan Y, Qiao R, Yao F, Zhang Z, Yang B, Guo Y, Xiao S, Wei R, Ouyang Z, Ding N., Ai H, Huang L (2011) A Missense mutation in PPARD causes a major QTL effect on ear size in pigs. PLoS Genet 7, e1002043. doi:10.1371/journal.pgen.1002043
23. Rothschild MF, Hu ZL, Jiang Z (2007) Advances in QTL mapping in pigs. Int J Biol Sci 3, 192-197
24. Roehe R, Plastow GS, Knap PW (2003) Quantitative and molecular genetic determination of protein and fat deposition. Homo 54, 119-131
25. Rückert C, Bennewitz J (2010) Joint QTL analysis of three connected F2-crosses on pigs. Genet Sel Evol 42, 40
26. Rückert C, Stratz P, Preuss S, Bennewitz J (2012) Mapping quantitative trait loci for metabolic and cytological fatness traits of connected F2 crosses in pigs. J Anim Sci 90, 399-409
27. Sanchez MP, Riquet J, Iannuccelli N, Gogué J, Billon Y, Demeure O, Caritez JC, Burgaud G, Fève K, Bonnet M, Péry C, Lagant H, Le Roy P, Bidanel JP, Milan D (2006) Effects of quantitative trait loci on chromosomes 1, 2, 4, and 7 on growth, carcass, and meat quality traits in backcross Meishan × Large White pigs. J Anim Sci 84, 526-537
28. Stratz P, Baes C, Rückert C, Preuss S, Bennewitz J. (2012) A two-step approach to map quantitative trait loci for meat quality in connected porcine F2 crosses considering main and epistatic effects. Anim Genet (accepted)
29. Varona L, Ovilo C, Clop A, Noguera JL, Pérez-Enciso M, Coll A, Folch JM, Barragán C, Toro MA, Babot D, Sánchez A (2002) QTL mapping for growth and carcass traits in an Iberian by Landrace pig intercross: additive, dominant and epistatic effects. Genet Res 80, 145-154
30. Walling GA, Visscher PM, Andersson L, Rothschild MF, Wang L, Moser G, Groenen MAM, Bidanel JP, Cepica S, Archibald AL, Geldermann H, de Koning DJ, Milan D, Haley CS (2000) Combined analyses of data from quantitative trait loci mapping studies: Chromosome 4 effects on porcine growth and fatness. Genetics 155, 1369-1378
31. Wimmers K, Murani E, Te Pas MFW, Chang KC, Davoli R, Merks JWM, Henne H, Muraniova M, Da Costa N, Harlizius B, Schellander K, Böll I, Braglia S, De Wit AAC, Cagnazzo M, Fontanesi L, Prins D, Ponsuksili S (2007) Associations of functional candidate genes derived from gene-expression profiles of prenatal porcine muscle tissue with meat quality and muscle deposition. Anim Genet 38, 474-484