ROCK1 inhibition promotes the self-renewal of a novel mouse mammary cancer stem cell

Stem Cells

Volumn 31, Issue 1, 2013, Pages 12-22

  Castro, David J ^a   Maurer, Jochen ^a   Hebbard, Lionel ^b   Oshima, Robert G ^a  

^a BURNHAM INSTITUTE   (United States)

^b WESTMEAD HOSPITAL   (Australia)

Author keywords

Breast cancer; Cancer stem cell; Epithelial mesenchymal transition; Keratin; ROCK1

Indexed keywords

CYTOKERATIN 14; CYTOKERATIN 8; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; GLYCOGEN SYNTHASE KINASE 3BETA INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE INHIBITOR; RHO ASSOCIATED COILED COIL CONTAINING PROTEIN KINASE 1; RHO ASSOCIATED COILED COIL CONTAINING PROTEIN KINASE 1 INHIBITOR; RHO KINASE; UNCLASSIFIED DRUG; WNT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST CANCER; CANCER STEM CELL; CARCINOGENICITY; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL LINEAGE; CELL RENEWAL; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; FEMALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION PROFILING; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, ANIMAL; MAMMARY TUMOR VIRUS, MOUSE; MICE; MICE, TRANSGENIC; NEOPLASTIC STEM CELLS; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED; WNT1 PROTEIN;

EID: 84871548137     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1224     Document Type: Article

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