Fine Tuning the Inhibition Profile of Cyclosporine A by Derivatization of the MeBmt Residue

ChemBioChem

Volumn 14, Issue 1, 2013, Pages 63-65

  Prell, Erik ^a   Kahlert, Viktoria ^a   Rücknagel, Karl Peter ^a   Malešević, Miroslav ^a   Fischer, Gunter ^a  

^a MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

Author keywords

Calcineurin; Cyclophilin; Cyclosporine A; Extracellular localization; Immunology; Inhibitors

Indexed keywords

3 HYDROXY 4 METHYL 2 METHYLAMINO 6 OCTENOIC ACID; CALCINEURIN; CALCINEURIN INHIBITOR; CYCLOPHILIN; CYCLOSPORIN A; PHOSPHATASE; THREONINE;

ALLERGIC ASTHMA; ARTICLE; CONFOCAL LASER MICROSCOPY; CONFORMATION; CRYSTAL STRUCTURE; DERIVATIZATION; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVITY; FUNGUS; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATORY DISEASE; ISOMERIZATION; PRIORITY JOURNAL; TOLYPOCLADIUM INFLATUM;

BIOLOGICAL TRANSPORT; CALCINEURIN; CYCLOPHILINS; CYCLOSPORINE; DRUG DESIGN; ENZYME INHIBITORS; EXTRACELLULAR SPACE; HUMANS; INTRACELLULAR SPACE; JURKAT CELLS; STRUCTURE-ACTIVITY RELATIONSHIP; THREONINE;

EID: 84871498469     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201200621     Document Type: Article

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