Adolescent amphetamine exposure elicits dose-specific effects on monoaminergic neurotransmission and behaviour in adulthood

International Journal of Neuropsychopharmacology

Volumn 15, Issue 9, 2012, Pages 1319-1330

  Labonte, Benoit ^a   McLaughlin, Ryan J ^a,b   Dominguez Lopez, Sergio ^a   Bambico, Francis Rodriguez ^a   Lucchino, Ilaria ^a,c   Ochoa Sanchez, Rafael ^a   Leyton, Marco ^a   Gobbi, Gabriella ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

adolescence; Amphetamine; drug abuse; in vivo electrophysiology; monoamine

Indexed keywords

AMPHETAMINE; DOPAMINE; NORADRENALIN; SEROTONIN;

ADULTHOOD; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; DRUG EXPOSURE; FEMALE; HIGH RISK BEHAVIOR; IN VIVO STUDY; LOCOMOTION; LOCUS CERULEUS; MAZE TEST; MONOAMINE NERVE CELL; MONOAMINERGIC SYSTEM; NEUROTRANSMISSION; NONHUMAN; OPEN FIELD TEST; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; VENTRAL TEGMENTUM;

AMPHETAMINE; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; BIOGENIC MONOAMINES; CENTRAL NERVOUS SYSTEM STIMULANTS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGICAL PHENOMENA; FEMALE; LOCUS COERULEUS; MOTOR ACTIVITY; NEURONS; NOREPINEPHRINE; PREGNANCY; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RISK-TAKING; SEROTONIN; SYNAPTIC TRANSMISSION; VENTRAL TEGMENTAL AREA;

EID: 84871488945     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145711001544     Document Type: Article

References (56)

1. Acevedo SF, Raber J (2011). Histamine-dependent behavioral response to methamphetamine in 12-month-old male mice. Brain Research 1393, 23-30.
2. Aghajanian GK, Vandermaelen CP (1982). Intracellular identification of central noradrenergic and serotonergic neurons by a new double labeling procedure. Journal of Neuroscience 2, 1786-1792.
3. Allers KA, Sharp T (2003). Neurochemical and anatomical identification of fast-and slow-firing neurones in the rat dorsal raphe nucleus using juxtacellular labelling methods in vivo. Neuroscience 122, 193-204.
4. Bambico FR, Nguyen NT, Katz N, Gobbi G (2010). Chronic exposure to cannabinoids during adolescence but not during adulthood impairs emotional behaviour and monoaminergic neurotransmission. Neurobiology of Disease 37, 641-655.
5. Baraban JM, Aghajanian GK (1980). Suppression of serotonergic neuronal firing by alpha-adrenoceptor antagonists : evidence against GABA mediation. European Journal of Pharmacology 66, 287-294.
6. Biała G, Kruk M (2007). Amphetamine-induced anxiety-related behavior in animal models. Pharmacological Reports 59, 636-644.
7. Blier P, de Montigny C (1994). Current advances and trends in the treatment of depression. Trends in Pharmacological Sciences 15, 220-226.
8. Bortolozzi A, Artigas F (2003). Control of 5-hydroxytryptamine release in the dorsal raphe nucleus by the noradrenergic system in rat brain. Role of alpha-adrenoceptors. Neuropsychopharmacology 28, 421-434.
9. Burton CL, Nobrega JN, Fletcher PJ (2010). The effects of adolescent methylphenidate self-administration on responding for a conditioned reward, amphetamine-induced locomotor activity, and neuronal activation. Psychopharmacology (Berlin) 208, 455-468.
10. Cancela LM, Basso AM, Martijena ID, Capriles NR, et al. (2001). A dopaminergic mechanism is involved in the 'anxiogenic-like' response induced by chronic amphetamine treatment: a behavioral and neurochemical study. Brain Research 909, 179-186.
11. Carlezon Jr. WA, Mague SD, Andersen SL (2003). Enduring behavioral effects of early exposure to methylphenidate in rats. Biological Psychiatry 54, 1330-1337.
12. Caster JM, Walker QD, Kuhn CM (2005). Enhanced behavioral response to repeated-dose cocaine in adolescent rats. Psychopharmacology (Berlin) 183, 218-225.
13. Chambers RA, Taylor JR, Potenza MN (2003). Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. American Journal of Psychiatry 160, 1041-1052.
14. Chen CY, Storr CL, Anthony JC (2009). Early-onset drug use and risk for drug dependence problems. Addictive Behaviors 34, 319-322.
15. Cortese BM, Mitchell TR, Galloway MP, Prevost KE, et al. (2010). Region-specific alteration in brain glutamate: possible relationship to risk-taking behavior. Physiology and Behavior 99, 445-450.
16. Creese I, Iversen SD (1974). The role of forebrain dopamine systems in amphetamine induced stereotyped behavior in the rat. Psychopharmacologia 39, 345-357.
17. Estelles J, Lluch J, Rodriguez-Arias M, Aguilar MA, et al. (2007). Cocaine exposure during adolescence affects anxiety in adult mice. Brain Research Bulletin 71, 393-403.
18. Fletcher PJ, Tampakeras M, Sinyard J, Higgins GA (2007). Opposing effects of 5-HT(2A) and 5-HT(2C) receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test. Psychopharmacology (Berlin) 195, 223-234.
19. Gervais J, Rouillard C (2000). Dorsal raphe stimulation differentially modulates dopaminergic neurons in the ventral tegmental area and substantia nigra. Synapse 35, 281-291.
20. Gobbi G, Bambico FR, Mangieri R, Bortolato M, et al. (2005). Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proceedings of the National Academy of Sciences USA 102, 18620-18625.
21. Grace AA, Bunney BS (1983). Intracellular and extracellular electrophysiology of nigral dopaminergic neurons-1. Identification and characterization. Neuroscience 10, 301-315.
22. Guiard BP, El Mansari M, Blier P (2008a). Cross-talk between dopaminergic and noradrenergic systems in the rat ventral tegmental area, locus ceruleus, and dorsal hippocampus. Molecular Pharmacology 74, 1463-1475.
23. Guiard BP, El Mansari M, Merali Z, Blier P (2008b). Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions. International Journal of Neuropsychopharmacology 11, 625-639.
24. Haddjeri N, Blier P, de Montigny C (1997). Effects of long-term treatment with the alpha 2-adrenoceptor antagonist mirtazapine on 5-HT neurotransmission. Naunyn Schmiedebergs Archives of Pharmacology 355, 20-29.
25. Kalivas PW, Stewart J (1991). Dopamine transmission in the initiation and expression of drug-and stress-induced sensitization of motor activity. Brain Research. Brain Research Reviews 16, 223-244.
26. Kuczenski R, Segal D (1989). Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis. Journal of Neuroscience 9, 2051-2065.
27. Kuczenski R, Segal DS (1997). Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine. Journal of Neurochemistry 68, 2032-2037.
28. Kuczenski R, Segal DS, Cho AK, Melega W (1995). Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine. Journal of Neuroscience 15, 1308-1317.
29. Laviola G, Adriani W, Terranova ML, Gerra G (1999). Psychobiological risk factors for vulnerability to psychostimulants in human adolescents and animal models. Neuroscience and Biobehavioral Reviews 23, 993-1010.
30. Legault M, Wise RA (2001). Novelty-evoked elevations of nucleus accumbens dopamine : dependence on impulse flow from the ventral subiculum and glutamatergic neurotransmission in the ventral tegmental area. European Journal of Neuroscience 13, 819-828.
31. Mague SD, Andersen SL, Carlezon Jr. WA (2005). Early developmental exposure to methylphenidate reduces cocaine-induced potentiation of brain stimulation reward in rats. Biological Psychiatry 57, 120-125.
32. McPherson CS, Lawrence AJ (2006). Exposure to amphetamine in rats during periadolescence establishes behavioural and extrastriatal neural sensitization in adulthood. International Journal of Neuropsychopharmacology 9, 377-392.
33. Muller CP, Carey RJ, Huston JP, De Souza Silva MA (2007). Serotonin and psychostimulant addiction: focus on 5-HT1A-receptors. Progress in Neurobiology 81, 133-178.
34. Pattij T, Vanderschuren LJ (2008). The neuropharmacology of impulsive behaviour. Trends in Pharmacological Sciences 29, 192-199.
35. Paxinos G, Watson C (1986). The Rat Brain in Stereotaxic Coordinates, 2nd edn. San Diego, CA, USA: Academic Press Inc.
36. Pudovkina OL, Cremers TI, Westerink BH (2003). Regulation of the release of serotonin in the dorsal raphe nucleus by alpha1 and alpha2 adrenoceptors. Synapse 50, 77-82.
37. Robinson TE, Kolb B (2004). Structural plasticity associated with exposure to drugs of abuse. Neuropharmacology 47 (Suppl. 1), 33-46.
38. Rothman RB, Baumann MH (2006). Balance between dopamine and serotonin release modulates behavioral effects of amphetamine-type drugs. Annals of the New York Academy of Sciences 1074, 245-260.
39. Rothman RB, Baumann MH, Dersch CM, Romero DV, et al. (2001). Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse 39, 32-41.
40. Roybal K, Theobold D, Graham A, DiNieri JA, et al. (2007). Mania-like behavior induced by disruption of CLOCK. Proceedings of the National Academy of Sciences USA 104, 6406-6411.
41. Salomon L, Lanteri C, Glowinski J, Tassin JP (2006). Behavioral sensitization to amphetamine results from an uncoupling between noradrenergic and serotonergic neurons. Proceedings of the National Academy of Sciences USA 103, 7476-7481.
42. Santucci AC, Rosario A (2010). Anxiety-like responses in adolescent rats following a 10-11-day withdrawal period from repeated cocaine administration. Brain Research Bulletin 81, 441-444.
43. Seager MA, Huff KD, Barth VN, Phebus LA, et al. (2004). Fluoxetine administration potentiates the effect of olanzapine on locus coeruleus neuronal activity. Biological Psychiatry 55, 1103-1109.
44. Sessions GR, Meyerhoff JL, Kant GJ, Koob GF (1980). Effects of lesions of the ventral medial tegmentum on locomotor activity, biogenic amines and responses to amphetamine in rats. Pharmacology, Biochemistry and Behavior 12, 603-608.
45. Sills TL, Greenshaw AJ, Baker GB, Fletcher PJ (1999). Acute fluoxetine treatment potentiates amphetamine hyperactivity and amphetamine-induced nucleus accumbens dopamine release : possible pharmacokinetic interaction. Psychopharmacology (Berlin) 141, 421-427.
46. Spear LP (2000). The adolescent brain and age-related behavioral manifestations. Neuroscience and Biobehavioral Reviews 24, 417-463.
47. Spear LP, File SE (1996). Methodological considerations in neurobehavioral teratology. Pharmacology, Biochemistry and Behavior, 55, 455-457.
48. SAaMHSAOoA (2009). The NSDUH Report: Nonmedical use of Adderall1 among full-time college students. Substance Abuse and Mental Health Services Administration, Office of Applied Studies, Rockville, MD.
49. Szabo ST, Blier P (2002). Effects of serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibition plus 5-HT(2A) receptor antagonism on the firing activity of norepinephrine neurons. Journal of Pharmacology and Experimental Therapeutics 302, 983-991.
50. Tassin JP (2008). Uncoupling between noradrenergic and serotonergic neurons as a molecular basis of stable changes in behavior induced by repeated drugs of abuse. Biochemical Pharmacology 75, 85-97.
51. Toledo-Rodriguez M, Sandi C (2011). Stress during adolescence increases novelty seeking and risk-taking behavior in male and female rats. Frontiers in Behavioral Neuroscience 5, 1-10.
52. UNODC (2010). World drug report (http://www.unodc.org/documents/data-and- analysis/WDR2010/Youth-school-amphetamines.pdf). United Nations Office on Drugs and Crime. Accessed 19 May 2011.
53. Weiss SM, Wadsworth G, Fletcher A, Dourish CT (1998). Utility of ethological analysis to overcome locomotor confounds in elevated maze models of anxiety. Neuroscience and Biobehavioral Reviews 23, 265-271.
54. van Heerden JH, Russell V, Korff A, Stein DJ, et al. (2010). Evaluating the behavioural consequences of early maternal separation in adult C57BL/6 mice; the importance of time. Behavioral Brain Research 207, 332-342.
55. Vanderschuren LJ, Kalivas PW (2000). Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization : a critical review of preclinical studies. Psychopharmacology (Berlin) 151, 99-120.
56. Vuong SM, Oliver HA, Scholl JL, Oliver KM, et al. (2010). Increased anxiety-like behavior of rats during amphetamine withdrawal is reversed by CRF2 receptor antagonism. Behavioral Brain Research 208, 278-281.