The role of tau protein in alzheimers disease: An update

Chinese Pharmacological Bulletin

Volumn 20, Issue 10, 2004, Pages 1088-1089

  Zhou, Ning ^a   Du, Guan Hua ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Alzheimers disease; Microtubule; Neurofibrillary tangles; Tau

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN; TAU PROTEIN;

ALZHEIMER DISEASE; IN VITRO STUDY; MICROTUBULE; NEUROFIBRILLARY TANGLE; PAIRED HELICAL FILAMENT; POLYMERIZATION;

EID: 84871484393     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Cleveland DW, Hwo SY, Kirschner MW. Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly[J]. J Mol Bio, 1977, 116(2): 227-47.
2. Arrasate M, Perez M, Avila J. Tau dephosphorylation at tau-1 site correlates with It's association to cell membrane [J]. Neurochem, Res, 2000, 25(1):43-50.
3. Arrasate M, Perez M, Valpuesta JM et al. Role of glycosaminoglycans In determining the helicity of paired helical filaments [J]. Am J Pathol, 1997, 151 (4): 1115-22.
4. Goode BL, Denis PE, Panda D et al. Functional Interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly[J]. Mol Biol Cell, 1997, 8(2): 353-65.
5. Gorath M, Stahnke T, Mronga T et al. Developmental changes of tau protein and mRNA in cultured rat brain oligodendrocytes[J]. Glia, 2001, 36: 89-101.
6. Klein CE, Kramer M, Cardine AM et al. Process outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tau[J]. J Neurosci, 2002, 22; 698-707.
7. Tzivion G, Shen YH, Zhu J et al. 14-3-3 proteins: bringing new definitions to scaffolding[J]. Oncogene, 2001, 21:6331-8.
8. Liu CW, Lee G, Jay DG et al. Tau is required for neurite outgrowth and growth cone motility of chick sensory neurons[J]. Cell Motil Cytoskeleton, 1999, 43: 232-42.
9. Dawson HN, Ferreira A, Eyster MV et al. Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice[J]. J Cell Sci, 2001, 114: 1179-87.
10. Harada A, Oguchi K, Okabe S et al. Altered microtubule organization in small-calibre axons of mice lacking tau protein [J]. Natwe, 1994, 369: 488-91.
11. Takei Y, Teng J, Harada A et al. Defects in axonal elongation and neuronal migration in mice with disrupted tau and maplb gene [J]. J Cell Biol, 2000, 150: 989-1000.
12. Harada A, Oguchi K, Okabe S et al. Altered microtubule organization in small-calibre axons of mice lacking tau protein[J]. Nature, 1994, 369: 488-91.
13. Thomas F, Jochen E, Roland B. Tau-mediated cytotoxicity in a pseudohyper-phosphorylation model of Alzheimer's disease[J]. J Neuroscience, 2002, 22(22): 9733-41.
14. Mosrsch R, Simon W, Coleman PD. Neurons may live for decades with neurofibrillary tangles [J]. Neuropathol and Exp Neurol, 1999, 58:188-97.
15. Goedert M, Hasegawa M, Jakes R et al. Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases [J].FEBS Lett, 1997, 409:57-62.
16. Drewes G, Ebneth A, Preuss U et al. MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption [J]. Cell, 1997, 89: 297-308.
17. Sadot E, Gurwitz D, Barg J et al. Activation of ml muscarinic acetylcholine receptor regulates tau phosphorylation in transfected PC12 cell[J]. J Neurochem, 1996, 66: 877-880.
18. Islam K, Levy E. Carboxyl-terminal fragments of beta-amyloid precursor protein bind to microtubules and the associated protein tau[J]. Am J Pathol, 1997, 151: 265-71.
19. Schmidt ML, DiDario AG, Lee VM, Trojanowski JQ. An extensive network of PHF tau-rich dystrophic neurites permeates neocortex and nearly all neuritic and diffuse amyloid plaques in Alzheimer disease[J]. FEBS Lett, 1994, 344; 69-73.
20. Busciglio J, Lorenzo A, Yeh J et al. β-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding [J]. Neuron, 1995, 14(4): 879.
21. Alvarez A, Tore R, Caceres A et al. Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death[J]. FEBS Leu, 1999, 459(3): 421-6.
22. Khatoon S, Grundke-Iqbal I, Iqbal K. Brain levels of microtu-bule- associated protein tau are elevated in Alzheimer's disease; a radioimmuno-slot-blot assay for nanograms of the protein [J]. J Neurochem, 1992, 59(2): 750-3.
23. Stamer K, Vogel R, Thies E et al. Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress[J]. J Cell Biol, 2002, 156(6): 1051-63.
24. Xu H, Sweeney D, Wang R et al. Generation of Alzheimer Beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation[J]. Proc Natl Acad Sci USA, 1997, 94: 3748-52.
25. Rapoport M, Dawson HN, Binder LI et al. Tau is essential to beta-amyloid-induced neurotoxicity [J]. Proc Natl Acad Sci USA, 2002, 99(9): 6364-9.
26. Shoji M, Matsubara E, Murakami T. et al. Cerebrospinal fluid tau in dementia disorders: a large scale multicenter study by a Japanese study group [J]. Neurobiol Aging, 2002, 23(3); 363-70.
27. Hu YY, He SS, Wang X et al. Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients: an ultrasensitive bienzyme-substrate-recycte enzymelinked immunosorbent assay [J]. Am J Pathol, 2002, 160(4); 1269-78.
28. Hattori H, Matsumoto M, Iwai K et al. The tau protein of oral epithelium increases in Alzheimer's disease[J]. J Gerontol A Biol Sci Med Sci, 2002, 57(1). 64-70.
29. Perez M, Hernandez F, Gomez Ramos A et al. Formation of aberrant phosphotau fibrillar polymers In neural cultured cells [J]. Eur J Biechem, 2002, 269: 1484-9.
30. Sayre LM, Zelasko DA, harris PL et al. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are Increased In Alzheimer's disease[J]. J Neruochem, 1997, 68; 2092-7.
31. Pratieo D, Uryu K, Leight S et al. Increased lipid peroxidation precedes amyloid plaque formation In an animal model of Alzheimer amyloidosis[J].J Neruosci, 2001, 21: 4183-7.
32. Liwen Ko, Michael Deture, Naruhiko Sahara et al. Cellular Models for Tau Filament Assembly [J]. Journal of Molecular Neuroscience, 2002, 19: 311-5.
33. Hall GF, Lee S, Yao J. Neurofibrillary degeneration can be arrested In an In vivo cellular model of human tauopathy by application of a compound which Inhibits tau filament formation In vitro [J]. Journal of Molecular Neuroscience, 2002, 19; 253-60.