Increased brain uptake of docetaxel and ketoconazole loaded folate-grafted solid lipid nanoparticles

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 9, Issue 1, 2013, Pages 111-121

  Venishetty, Vinay Kumar ^a,b   Komuravelli, Rojarani ^c   Kuncha, Madhusudana ^b   Sistla, Ramakrishna ^b   Diwan, Prakash V ^b,d  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^c KAKATIYA UNIVERSITY   (India)

^d Lalitha College of Pharmacy   (India)

Author keywords

Brain permeation coefficient; Docetaxel; Folic acid; Ketoconazole; Pharmacokinetics; Solid lipid nanoparticles

Indexed keywords

DOCETAXEL; FOLIC ACIDS; KETOCONAZOLE; PERMEATION COEFFICIENTS; SOLID LIPID NANOPARTICLE (SLN);

CELL CULTURE; DRUG INTERACTIONS; ENDOTHELIAL CELLS; GRAFTING (CHEMICAL); NANOPARTICLES; ORGANIC ACIDS; PHARMACOKINETICS; ZETA POTENTIAL;

DRUG PRODUCTS;

DOCETAXEL; FOLIC ACID; KETOCONAZOLE; SOLID LIPID NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BRAIN; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG STABILITY; DRUG UPTAKE; ENDOTHELIUM CELL; IC 50; IN VITRO STUDY; LIPOPHILICITY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PHARMACOKINETICS; RAT; ZETA POTENTIAL;

ANIMALS; BRAIN; CELL LINE; FOLIC ACID; KETOCONAZOLE; LIPIDS; NANOPARTICLES; PARTICLE SIZE; RATS; RATS, WISTAR; TAXOIDS;

EID: 84871463694     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2012.03.003     Document Type: Article

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