Combination of real-time polymerase chain reaction assay and serum galactomannan in the diagnosis of invasive aspergillosis in patients with hematological malignancies and recipients of hematopoietic stem cell transplantation

National Medical Journal of China

Volumn 90, Issue 6, 2010, Pages 375-378

  Sun, Yu Qian ^a   Ji, Yu ^a   Xu, Lan Ping ^a   Liu, Dai Hong ^a   Liu, Kai Yan ^a   Huang, Xiao Jun ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

Aspergillosis; Hematologic neoplasms; Hematopoietic stem cell transplantation; Mannans; Polymerase chain reaction

Indexed keywords

GALACTOMANNAN; MANNAN;

ARTICLE; DIAGNOSTIC VALUE; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN TISSUE; INVASIVE ASPERGILLOSIS; MAJOR CLINICAL STUDY; PREDICTIVE VALUE; REAL TIME POLYMERASE CHAIN REACTION; ADOLESCENT; ADULT; AGED; ASPERGILLOSIS; BLOOD; BLOOD DISEASE; CHEMISTRY; CHILD; EVALUATION; FEMALE; MALE; METHODOLOGY; MIDDLE AGED; POLYMERASE CHAIN REACTION; SERUM;

ADOLESCENT; ADULT; AGED; ASPERGILLOSIS; CHILD; FEMALE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; MANNANS; MIDDLE AGED; POLYMERASE CHAIN REACTION; SERUM; YOUNG ADULT;

EID: 84871449990     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0376-2491.2010.06.005     Document Type: Article

References (12)

1. Pferffer C D, Fine J P, Safdar N. Diagnosis of invasive aspergillosis using a galactomannan assay: a meta-analysis. Clin Infect Dis, 2006, 42: 1417-1427.
2. 2009, 19: 145-148.
3. Mennink-Kersten M A, Donnelly J P, Verweij P E. Detection fo circulating galactomannan for the diagnosis and management of invasive aspergillosis. Lancet Infect Dis, 2004, 4: 349-357.
4. Mengoli C, Cruciani M, Barnes R A, et al. Use of PCR for diagnosis of invasive aspergillosis: systematic review and metaanalysis. Lancet Infect Dis, 2009, 9: 89-96.
5. Huang X J, Liu D H, Liu K Y, et al. Haploidentical hematopoietic stem cell transplantation without in vitro T-cell depletion for the treatment of hematological malignancies. Bone Marrow Transplant, 2006, 38: 291-297.
6. 2007, 28: 83-86.
7. 2007, 46: 607-611.
8. White P L, Linton C J, Perry M D, et al. The evolution and evaluation of a whole blood polymerase chain reaction assay for the detection of invasive aspergillosis in hematology patients in a routine clinical setting. Clin Infect Dis, 2006, 42: 479-486.
9. Costa C, Costa J M, Desterke C, et al. Real-time PCR coupled with automated DNA extraction and detection of galactomannan antigen in serum by enzyme-linked immunosorbent assay for diagnosis of invasive aspergillosis. J Clin Microbiol, 2002, 40: 2224-2227.
10. Millon L, Piarroux R., Deconinck E, et al. Use of real-time PCR to process the first galactomannan positive serum sample in diagnosing invasive aspergillosis. J Clin Microbiol, 2005, 43: 5097-5101.
11. Florent M, Katsahian S, Vekhoff A, et al. Prospective evaluation of a polymerase chain reaction-ELISA targeted to Aspergillus fumigatus and Aspergillus flavus for the early diagnosis of invasive aspergillosis in patients with hematological malignancies. J Infect Dis, 2006, 193: 741-747.
12. Cuenca-Estrella M, Meije Y, Diaz-Pedroche C, et al. Value of serial quantification of fungal DNA by a real-time PCR-based technique for early diagnosis of invasive aspergillosis in patients with febrile neutropenia. J Clin Microbiol, 2009, 47: 379-384.