Impairment of brain redox homeostasis caused by the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome in vivo

Metabolic Brain Disease

Volumn 27, Issue 4, 2012, Pages 521-530

  Viegas, Carolina Maso ^a   Tonin, Anelise Miotti ^a   Zanatta, Ǎngela ^a   Seminotti, Bianca ^a   Busanello, Estela Natacha Brandt ^a   Fernandes, Carolina Gonçalves ^a   Moura, Alana Pimentel ^a   Leipnitz, Guilhian ^a   Wajner, Moacir ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Ammonia; Cerebral cortex; Homocitrulline; Hyperornithinemia hyperammonemia homocitrullinuria syndrome; Ornithine; Oxidative stress

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HOMOCITRULLINE; ORNITHINE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; ENZYME ACTIVITY; HOMEOSTASIS; HYPERORNITHINEMIA HYPERAMMONEMIA HOMOCITRULLINURIA SYNDROME; IN VIVO STUDY; LIPID PEROXIDATION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; RAT;

AMINO ACID METABOLISM, INBORN ERRORS; AMMONIA; ANIMALS; ANTIOXIDANTS; BRAIN; CATALASE; CITRULLINE; GLUTATHIONE PEROXIDASE; HOMEOSTASIS; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENTRICULAR; MALE; NITRIC OXIDE; ORNITHINE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; SULFHYDRYL COMPOUNDS; THIOBARBITURIC ACID REACTIVE SUBSTANCES; UREASE;

RATTUS;

EID: 84871436504     PISSN: 08857490     EISSN: 15737365     Source Type: Journal    
DOI: 10.1007/s11011-012-9327-5     Document Type: Article

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