Polyneuropathy induced by HIV disease and antiretroviral therapy

Clinical Neurophysiology

Volumn 124, Issue 1, 2013, Pages 176-182

  Kokotis, Panagiotis ^a   Schmelz, Martin ^b   Papadimas, Georgios K ^a   Skopelitis, Elias E ^c   Aroni, Kyriaki ^c   Kordossis, Theodore ^c   Karandreas, Nikolaos ^a  

^a NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c LAIKO GENERAL HOSPITAL   (Greece)

Author keywords

HAART; HIV disease; Polyneuropathy

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; AGED; ANKLE; ARTICLE; BASEMENT MEMBRANE; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; DENSITY; DISEASE SEVERITY; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; INTRAEPIDERMAL NERVE FIBER DENSITY; MAJOR CLINICAL STUDY; MALE; MEDIAN NERVE; NERVE CONDUCTION; NERVE FIBER; NEUROTOXICITY; POLYNEUROPATHY; PRIORITY JOURNAL; SKIN BIOPSY; THIGH; TREATMENT RESPONSE; VELOCITY;

ADULT; AGED; AIDS-ASSOCIATED NEPHROPATHY; ANKLE; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BIOPSY; FEMALE; HIV INFECTIONS; HIV SEROPOSITIVITY; HUMANS; MALE; MIDDLE AGED; NERVE FIBERS; NERVE FIBERS, UNMYELINATED; NEURAL CONDUCTION; POLYNEUROPATHIES; SKIN; SYMPATHETIC NERVOUS SYSTEM; THIGH; YOUNG ADULT;

EID: 84871422320     PISSN: 13882457     EISSN: 18728952     Source Type: Journal    
DOI: 10.1016/j.clinph.2012.05.022     Document Type: Article

References (38)

1. Brinley F.J., Pardo C.A., Verma A. Human immunodeficiency virus and the peripheral nervous system workshop. Arch Neurol 2001, 58:1561-1566.
2. Cherry C.L., McArthur J.C., Hoy J.F., Wesselingh S.L. Nucleoside analogues and neuropathy in the era of HAART. J Clin Virol 2003, 26:195-207.
3. Currier J.S., Havlir D.V. Complications of HIV disease and antiretroviral therapy. Top HIV Med 2009, 17:57-67.
4. Dalakas M.C. Peripheral neuropathy and antiretroviral drugs. J Peripher Nerv Syst 2001, 6:14-20.
5. Devigili G., Tugnoli V., Penza P., Camozzi F., Lombardi R., Melli G., et al. The diagnostic criteria for small fiber neuropathy: from symptoms to neuropathology. Brain 2008, 131:1912-1925.
6. Ferrari S., Vento S., Monaco S., Cavallaro T., Cainelli F., Rizzuto N., et al. Human immunodeficiency virus - associated peripheral neuropathies. Mayo Clin Proc 2006, 81:213-219.
7. Hahn K., Robinson B., Anderson C., Li W., Pardo C.A., Morgello S., Simpson D., et al. Differential effects of HIV infected macrophages on dorsal root ganglia neurons and axons. Exp Neurol 2008, 210:30-40.
8. Herrmann D.N., Griffin J.W., Hauer P., Cornblath D.R., McArthur J.C. Epidermal nerve fiber density and sural nerve morphometry in peripheral neuropathies. Neurology 1999, 53:1634-1640.
9. Herrmann D.N., McDermott M.P., Henderson D., Chen L., Akowuah K., Schifitto G. North East AIDS Dementia (NEAD) Consortium. Epidermal nerve fiber density, axonal swellings and QST as predictors of HIV distal sensory neuropathy. Muscle Nerve 2004, 29:420-427.
10. Hoeldtke R., Davis K., Hshieh P., Gaspar S., Dworkin G. Autonomic surface potential analysis: assessment of reproducibility and sensibility. Muscle Nerve 1992, 15:926-931.
11. Holland N.R., Stocks A., Hauer P., Cornblath D.R., Griffin J.W., McArthur J.C. Intraepidermal nerve fiber density in patients with painful sensory neuropathy. Neurology 1997, 48:708-711.
12. Hsieh S.T., Chiang H.Y., Lin W.M. Pathology of nerve terminal degeneration in the skin. J Neuropathol Exp Neurol 2000, 59:297-307.
13. Kalliomaki M., Kieseritzky J.V., Schmidt R., Hagglof B., Karlsten R., Sjogren N., et al. Structural and functional differences between neuropathy with and without pain?. Exp Neurol 2011, 231:199-206.
14. Kennedy W.R., Wendelschafer-Crabb G., Johnson T. Quantitation of epidermal nerves in diabetic neuropathy. Neurology 1996, 47:1042-1048.
15. Keswani S.C., Jack C., Zhou C., Höke A. Establishment of a rodent model of HIV-associated sensory neuropathy. J Neurosci 2006, 26:10299-10304.
16. Kokotis P., Schmelz M., Skopelitis E.E., Kordossis T., Karandreas N. Differential sensitivity of thick and thin fibers to HIV and therapy-induced neuropathy. Auton Neurosci 2007, 136:90-95.
17. Lauria G., Bakkers M., Schmitz C., Lombardi R., Penza P., Devigili G., et al. Intraepidermal nerve fiber density at the distal leg: a worldwide normative reference study. J Peripher Nerv Syst 2010, 15:202-207.
18. Lauria G., Cornblath D.R., Johansson O., McArthur J.C., Mellgren S.I., Nolano M., et al. European Federation of Neurological Societies. EFNS guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy. Eur J Neurol 2005, 12:747-758.
19. Lauria G., Devigili G. Skin biopsy as a diagnostic tool in peripheral neuropathy. Nat Clin Pract Neurol 2007, 3:546-557.
20. Lauria G., Holland N., Hauer P., Cornblath D.R., Griffin J.W. McArthur JC Epidermal innervation: changes with aging, topographic location, and in sensory neuropathy. J Neurol Sci 1999, 164:172-178.
21. Lauria G., Hsieh S.T., Johansson O., Kennedy W.R., Leger J.M., Mellgren S.I., et al. European Federation of Neurological Societies/Peripheral Nerve Society Guideline on the use of skin biopsy in the diagnosis of small fiber neuropathy. Report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society. Eur J Neurol 2010, 17:903-909.
22. Letendre S., Ellis R.J. Neurologic complications of HIV disease and their treatments. Top HIV Med 2006, 14:21-26.
23. Madduri S., Papaloïzos M., Gander B. Synergistic effect of GDNF and NGF on axonal branching and elongation in vitro. Neurosci Res 2009, 65:88-97.
24. McArthur J.C., Stocks E.A., Hauer P., Cornblath D.R., Griffin J.W. Epidermal nerve fiber density: normative reference range and diagnostic efficiency. Arch Neurol 1998, 55:1513-1520.
25. McCarthy B.G., Hsieh S.T., Stocks A., Hauer P., Macko C., Cornblath D.R., et al. Cutaneous innervation in sensory neuropathies: evaluation by skin biopsy. Neurology 1995, 45:1848-1855.
26. Melli G., Keswani S.C., Fischer A., Chen W., Höke A. Spatially distinct and functionally independent mechanisms of axonal degeneration in a model of HIV-associated sensory neuropathy. Brain 2006, 129:1330-1338.
27. Pardo C.A., McArthur J.C., Griffin J.W. HIV neuropathy: insights in the pathology of HIV peripheral nerve disease. J Peripher Nerv Syst 2001, 6:21-27.
28. Parisi L., Rossi P., Valente G., Fattapposta F., Mellina V., Martini A., et al. Estimation of the conduction velocity of sympathetic sudomotor C fibres in healthy subjects: study of sympathetic skin reflex. Funct Neurol 2001, 16:231-237.
29. Rajan B., Polydefkis M., Hauer P., Griffin J.W., McArthur J.C. Epidermal reinnervation after intracutaneous axotomy in man. J Comp Neurol 2003, 457:24-36.
30. Robinson-Papp J., Simpson D.M. Neuromuscular diseases associated with HIV-1 infection. Muscle Nerve 2009, 40:1043-1053.
31. Simpson D.M., Kitch D., Evans S.R., McArthur J.C., Asmuth D.M., Cohen D., et al. ACTG A5117 Study Group. Neurology 2006, 66:1679-1687.
32. Skopelitis E., Kokotis P., Kontos A.N., Panayiotakoloulos G.D., Konstantinou K., Kordossis T., et al. Distal sensory polyneuropathy in HIV positive patients in the HAART era: an entity underestimated by clinical examination. Int J STD AIDS 2006, 17:467-472.
33. Skopelitis E., Aroni K., Kontos A.N., Konstantinou K., Kokotis P., Karandreas N., et al. Early detection of subclinical HIV sensory polyneuropathy using intraepidermal nerve fiber density quantification: association with HIV stage and surrogate markers. Int J STD AIDS 2007, 18:856-860.
34. Sommer C., Lauria G. Skin biopsy in the management of peripheral neuropathy. Lancet Neurol 2007, 6:632-642.
35. Toyokura M., Murakami K. Reproducibility of sympathetic skin response. Muscle Nerve 1996, 19:1481-1483.
36. Wallace V.C., Blackbeard J., Segerdahl A.R., Hasnie F., Pheby T., McMahon S.B., et al. Characterization of rodent models of HIV-gp120 and anti-retroviral-associated neuropathic pain. Brain 2007, 130:2688-2702.
37. Wendelschafer-Crabb G., Kennedy W.R., Walk D. Morphological features of nerves in skin biopsies. J Neurol Sci 2006, 242:15-21.
38. Zhou L., Kitch D.W., Evans S.R., Hauer P., Raman S., Ebenezer G.J., et al. NARC and ACTG A5117 Study Group. Neurology 2007, 68:2113-2119.