IL-1β, IL-6, IL-8, IL-10, IFN-γ, TNF-α and its relationship with lipid parameters in patients with major depression

Metabolic Brain Disease

Volumn 27, Issue 4, 2012, Pages 425-430

  Hocaoglu, Cicek ^a   Kural, Birgul ^b   Aliyazıcıoglu, Rezzan ^b   Deger, Orhan ^b   Cengiz, Sevil ^b  

^a RECEP TAYYIP ERDOGAN UNIVERSITY   (Turkey)

^b KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Cytokines; Immunoglobulins; Lipids; Major depressive disorders

Indexed keywords

CHOLESTEROL; CYTOKINE; GAMMA INTERFERON; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HUMAN; LIPID BLOOD LEVEL; MAJOR DEPRESSION; MALE; PROTEIN BLOOD LEVEL;

EID: 84871413580     PISSN: 08857490     EISSN: 15737365     Source Type: Journal    
DOI: 10.1007/s11011-012-9323-9     Document Type: Article

References (58)

1. Almeida-Montes LG, Valles-Sanchez V, Moreno-Aguilar J et al (2000) Relation-of serum cholesterol, lipid, serotonin and tryptophan levels to severity of depression and to suicide attempts. J Psychiatry Neurosci 25:371-377
2. Angele MK, Faist E (2002) Clinical review: immunodepression in the surgical patient and increased susceptibility to infection. Crit Care 6:298-305
3. Bao AM, Meynen G, Swaab DF (2008) The stress system in depression and neurodegeneration: focus on the human hypothalamus. Brain Res Rev 57:2531-2553
4. Barragan-Rodríguez L, Rodríguez-Morán M, Guerrero-Romero F (2007) Depressive symptoms and hypomagnesemia in older diabetic subjects. Arch Med Res 38:752-756
5. Bousquet C, Zatelli CM, Melmed S (2000) Direct regulation of pituitary proopiomelanocortin by STAT3 provides a novel mechanism for immuno- neuroendocrine interfacing. J Clin Invest 106:1417-1425
6. Brambilla F, Monteleone P (2004) Interleukin-1beta and tumor necrosis factor-Alpha in children with major depressive disorder or dysthymia. J Affect Disord 78(3):273-277
7. Choi SH, Suh KY (1998) Interleukin-1 beta, -2, -6 production, serum concentration and hypothalamic-pituitary-Adrenal axis in patients with major depression. J Korean Neuropsychiatr Assoc 37 (3):537-547
8. Colin A, Reggers J, Castronovo V (2003) Lipids, depression and suicide. Encephale 29:49-58
9. Connor TJ, Leonard EB (1998) Depressin, stress and immunological activation: the role of cytokines in depressive disorders. Life Sci 62(7):583-606
10. Das PP, Malhotra S, Chakrabarti S (2010) Elevated total cholesterol in severely depressed patients: role in cardiovascular risk. World J Biol Psychiatry 11(2):321-328
11. Ebesunun MO, Eruvulobi HU, Olagunju T (2012) Elevated plasma homocysteine in association with decreased vitamin B(12), folate, serotonin, lipids and lipoproteins in depressed patients. Afr J Psychiatry 15:25-29
12. Eby GA, Eby KL (2010) Magnesium for treatment-resistant depression: a review and hypothesis. Med Hypotheses 74:649-660
13. Farooqui AA (2009) Lipid mediators in the neural cell nucleus: their metabolism, signaling, and association with neurological disorders. Neuroscientist 15:392-407
14. Feingold KR, Hardardóttir I, Grunfeld C (1998) Beneficial effects of cytokine induced hyperlipidemia. Z Ernährungswiss 1:66-74
15. Glaser R, Kiecolt-Glaser KJ (2005) Stress-induced immune dysfunction: implications for health. Nat Rev Immunol 5(3):243-251
16. Grippo AJ, Johnson AK (2002) Biological mechanisms in the relationship between depression and heart disease. Neurosci Biobehav Rev 26(8):941-962
17. Himmerich H, Fulda S, Linseisen J et al (2008) Depression, comorbidities and the TNF-Alpha system. Eur Psychiatry 23(6):421-429
18. Huang TL, Lee CT (2007) T-helper 1/T-helper 2 cytokine imbalance and clinical phenotypes of acute-phase major depression. Psychiatry Clin Neurosci 61:415-420
19. Joynt KE, Whellan DJ, O'Connor CM (2003) Depression and cardiovascular disease: mechanisms of interaction. Biol Psychiatry 54:248-261
20. Katayama I, Bae SJ, Hamasaki Y et al (2001) Stress response, tachykinin, and cutaneous inflammation. J Investigative Dermatology Symposium Proceedings 6:81-86
21. Katon WJ, Rutter C, Simon G et al (2005) The association of comorbid depression with mortality in patients with type 2 diabetes. Diabetes Care 28:2668-2672
22. Khalid A, Lal N, Trivedi JK et al (1998) Serum lipids: new biological markers in depression ? Indian J Psychiatry 40:217-223
23. Kirpinar I, Caykoylu A, Coskun I et al (1998) Depresyonda plazma kolesterol ve trigliserid düzeyleri. Türk Psikiyatri Dergisi 9:23-27 (Turkish)
24. Kyrou I, Chrousos GP, Tsigos C (2006) Stress, visceral obesity, and metabolic complications. Ann N Y Acad Sci 1083:77-110
25. Lehto SM, Ruusunen A, Niskanen L, Tolmunen T et al (2010a) Elevated depressive symptoms and compositional changes in LDL particles in middle-Aged men. Eur J Epidemiol 25:403-409
26. Lehto SM, Niskanen L, Herzig KH et al (2010b) Serum chemokine levels in major depressive disorder. Psychoneuroendocrinology 35(2):226-232
27. Lima L, Pousada J, Barbosa C (2005) Magnesium deficiency and insulin resistance in patients with type 2 diabetes mellitus. Arq Bras Endocrinol Metabol 49:959-963
28. Loftis JM, Huckans M, Morasco BJ (2010) Neuroimmune mechanisms of cytokine-induced depression: current theories and novel treatment strategies. Neurobiol Dis 37:519-533
29. Ludewig B, Freigang S, Jäggi M et al (2000) Linking immunemediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model. Proc Natl Acad Sci 97:12752-12757
30. Lyness JM, Moynihan JA, Williford DJ et al (2001) Depression, medical illness, and interleukin-1beta in older cardiac patients. Int J Psychiatry Med 31(3):305-310
31. Maes M (1999) Major depression and activation of the inflammatory response system. In: Dantzer R (ed) Cytokines, stress and depression. Plenum, New York, pp 25-46
32. Maes M (2008) The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression. Neuro Endocrinol Lett 29:287-291
33. Maes M, Bosmans E, Meltzer HY (1993) Interleukin-1s: a putative mediator of HPA axis hyperactivity in majör depression? Am J Psychiatry 150:1189-1193
34. Maes M, Smith R, Christophe A (1997) Lower serum high-density lipoprotein cholesterol in major depression and in depressed men with serious suicidal attempts: relationship with immuneinflammatory markers. Acta Psychiatr Scand 95:212-221
35. Maier SF, Watkins LR (1998) Cytokines for psychologists: Implications of bidirectional immune-To-brain communication for understanding behavior, mood, and cognition. Psychol Rev 105(1):83-107
36. McLaren JE, Ramji DP (2009) Interferon gamma: a master regulator of atherosclerosis. Cytokine Growth Factor Rev 20:125-135
37. Michalec L, Choudhury BK, Postlethwait E (2002) CCL7 and CXCL10 orchestrate oxidative stress-induced neutrophilic lung inflammation. J Immunol 168:846-852
38. Mullington JM, Hinze-Selch D, Pollmavher T (2001) Mediators of inflammation. Ann N Y Acad Sci 933:201-210
39. Musselman DL, Betan E, Larsen H (2003) Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment. Biol Psychiatry 54(3):317-329
40. Nadler JL, Malayan S, Luong H (1992) Intracellular free magnesium deficiency plays a key role in increased platelet reactivity in type II diabetes mellitus. Diabetes Care 15:835-841
41. Olusi SO, Fido AA (1996) Serum lipid concentrations in patients with major depressive disorder. Biol Psychiatry 40:1128-1131
42. Oxenkrug GF, Branconnier RJ, Harto-Truax N et al (1983) Is serum cholesterol a biological marker for major depressive disorder? Am J Psychiatry 140:920-921
43. Partonen T, Haukka J, Virtamo J et al (1999) Association of low serum total cholesterol with major depression and suicide. Br J Psychiatry 175:259-262
44. Phillips LJ, McGorry PD, Garner B et al (2006) Stress, the hippocampus and the hypothalamic-pituitary-Adrenal axis: implications for the development of psychotic disorders. Aust N Z J Psychiatry 40 (9):725-741
45. Podlipný J, Hess Z, Vrzalová J et al (2010) Lower serum levels of interleukin-6 in a population sample with symptoms of depression than in a population sample without symptoms of depression. Physiol Res 59(1):121-126
46. Rafter D (2001) Biochemical markers of anxiety and depression. Psychiatry Res 103:93-96
47. Ruljancic N, Mihanovic M, Cepelak I (2011) Thrombocyte serotonin and serum cholesterol concentration in suicidal and non-suicidal depressed patients. Prog Neuropsychopharmacol Biol Psychiatry 3(5):1261-1267
48. Schiffer RB (1990) Depressive syndromes associated with diseases of the central nervous system. Semin Neurol 10:239-246
49. Schweiger U, Greggersen W, Rudolf S et al (2008) Disturbed glucose disposal in patients with major depression; application of the glucose clamp technique. Psychosom Med 70(2):170-176
50. Stokes KY, Gurwara S, Granger DN (2007) T-cell derived interferongamma contributes to arteriolar dysfunction during acute hypercholesterolemia. Arterioscler Thromb Vasc Biol 27:1998-2004
51. Tuglu C, Kara S (2003) Depression, cytokines and immune system. Bull Clin Psychopharmacol 13:142-150
52. Turnbull AV, Rivier CL (1999) Regulation of the hypothalamicpituitary- Adrenal axis by cytokines: actions and mechanisms of action. Physiol Rev 79(1):34-38
53. van Steenbergen-Weijenburg KM, van Puffelen AL et al (2011) More co-morbid depression in patients with Type 2 diabetes with multiple complications. An observational study at a specialized outpatient clinic. Diabet Med 28:86-89
54. Vila-del Sol V, Punzón C, Fresno M (2008) IFN-gamma-induced TNFalpha expression is regulated by interferon regulatory factors 1 and 8 in mouse macrophages. J Immunol 181:4461-4470
55. Weizman R, Laor N, Podliszewski E (1994) Cytokine production in major depressed patients before and after clomipramine treatment. Biol Psychiatry 35:42-47
56. Winokur A, Maislin G, Phillips JL (1988) Insulin resistance after oral glucose tolerance testing in patients with major depression. Am J Psychiatry 145:325-330
57. Winters TM, Hendrix AN, Zidron A (2005) Blood glucose correlations with depression, body habitus and caregiving status in the elderly Kenyan Luo grandparents. J Am Osteopath Assoc 105(1):2-28
58. Yary T, Soleimannejad K, Abd Rahim F (2010) Contribution of diet and major depression to incidence of acute myocardial infarction (AMI). Lipids Health Dis 18:9-13