A nanomaterial-based breath test for short-term follow-up after lung tumor resection

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 9, Issue 1, 2013, Pages 15-21

  Broza, Yoav Y ^a   Kremer, Ran ^b   Tisch, Ulrike ^a   Gevorkyan, Arsen ^a   Shiban, Ala ^a   Best, Lael Anson ^b   Haick, Hossam ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b Rambam Health Care Campus   (Israel)

Author keywords

Follow up; Lung cancer; Post surgery; Sensor; Volatile organic compound

Indexed keywords

BREATH TESTS; CLINICAL STUDY; FOLLOW-UP; LUNG CANCER; LUNG TUMOR; POST-SURGERY; PROOF OF CONCEPT; TARGET ORGANS;

BIOLOGICAL ORGANS; DISEASES; GAS CHROMATOGRAPHY; NANOSTRUCTURED MATERIALS; RADIOLOGY; SENSORS; TUMORS; VOLATILE ORGANIC COMPOUNDS;

SURGERY;

GOLD NANOPARTICLE; PLATINUM NANOPARTICLE;

AGED; ARTICLE; BREATH ANALYSIS; CANCER RADIOTHERAPY; CANCER SURGERY; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; FALSE POSITIVE RESULT; FEMALE; FOLLOW UP; HUMAN; LUNG CANCER; MALE; MASS FRAGMENTOGRAPHY; NANOTECHNOLOGY; SENSITIVITY AND SPECIFICITY; SENSOR;

BREATH TESTS; COHORT STUDIES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; LUNG NEOPLASMS; NANOTECHNOLOGY; VOLATILE ORGANIC COMPOUNDS;

EID: 84871408509     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2012.07.009     Document Type: Article

References (18)

1. Jemal A., Bray F., Center M.M., Ferlay J., Ward E., Forman D. Global cancer statistics. CA Cancer J Clin 2011, 61:69-90.
2. Szulejko J.E., McCulloch M., Jackson J., McKee D., Walker J., Solouki T. Evidence for cancer biomarkers in exhaled breath - a review. IEEE Sensors J 2010, 10:185-210.
3. Phillips M., Altorki N., Austin J.H.M., Cameron R.B., Cataneo R.N., Kloss R., et al. Detection of lung cancer using weighted digital analysis of breath biomarkers. Clin Chim Acta 2008, 393:76-84.
4. Peng G., Tisch U., Adams O., Hakim M., Shehada N., Broza Y.Y., et al. Diagnosing lung cancer in exhaled breath using gold nanoparticles. Nature Nanotechnol 2009, 4:669-673.
5. Peled N., Hakim M., Tisch U., Bunn P.A., Miller Y.E., Kennedy T.C., et al. Non-invasive breath analysis of pulmonary nodules. J Thorac Oncol 2012, 7:1528-1533.
6. Hakim M., Billan S., Tisch U., Peng G., Dvrokind I., Marom O., et al. Diagnosis of head-and-neck cancer from exhaled breath. Br J Cancer 2011, 104:1649-1655.
7. Barash O., Peled N., Hirsch F.R., Haick H. Sniffing the unique "odor print" of non-small-cell lung cancer with gold nanoparticles. Small 2009, 5:2618-2624.
8. Bajtarevic A., Ager C., Pienz M., Klieber M., Schwarz K., Ligor M., et al. Noninvasive detection of lung cancer by analysis of exhaled breath. BMC Cancer 2009, 9:348.
9. Poli D., Goldoni M., Caglieri A., Ceresa G., Acampa O., Carbognani P., et al. Breath analysis in non small cell lung cancer patients after surgical tumour resection. Acta Biomed 2008, 79:64-72.
10. Poli D., Carbognani P., Corradi M., Goldoni M., Acampa O., Balbi B., et al. Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study. Respir Res 2005, 6:71.
11. Peng G., Hakim M., Broza Y.Y., Billan S., Abdah-Bortnyak R., Kuten A., et al. Detection of lung, breast, colorectal, and prostate cancers from exhaled breath using a single array of nanosensors. Br J Cancer 2010, 103:542-551.
12. Tisch U., Billan S., Ilouze M., Phillips M., Peled N., Haick H. Volatile organic compounds in the exhaled breath as biomarkers for the early detection and screening of lung cancer. CML - Lung Cancer 2012, 5:107-117.
13. Broza YY, Gevorkyan A, Kremer R, Abdah-Bortnyak R, Haick H. Monitoring cancer treatment via exhaled breath. Presented at: Exhaled Breath Analysis: From Sensors to Devices and Applications Barga, Italy, October 24-29, 2010.
14. Dovgolevsky E., Konvalina G., Tisch U., Haick H. Monolayer-capped cubic platinum nanoparticles for sensing nonpolar analytes in highly humid atmospheres. J Phys Chem C 2010, 114:14042-14049.
15. Konvalina G., Haick H. Effect of humidity on nanoparticle-based chemiresistors: a comparison between synthetic and real-world samples. ACS Appl Mater Interfaces 2011, 4:317-325.
16. Darwiche K., Baumbach oI, Sommerwerck U., Teschler H., Freitag L. Bronchoscopically obtained volatile biomarkers in lung cancer. Lung 2011, 189:445-452.
17. Murray R, Granner D, Mayes P, Rodwell V. Harper's Illustrated Biochemistry, 27/e: McGraw Hill; 2006.
18. Halliwel B. Free radicals, antioxidants, and human disease: where are we now?. J Lab Clin Med 1992, 119:598-620.