It does not look odd to me: Perceptual impairments and eye movements in amnesic patients with medial temporal lobe damage

Neuropsychologia

Volumn 51, Issue 1, 2013, Pages 168-180

  Erez, Jonathan ^a   Lee, Andy C H ^a,b,c   Barense, Morgan D ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b ROTMAN RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Amnesia; Eye movements; Medial temporal lobe; Memory; Perception; Perirhinal cortex

Indexed keywords

ACCURACY; ADULT; AGED; AMNESIA; ARTICLE; BEHAVIOR CHANGE; BRAIN DAMAGE; CASE REPORT; CONTROLLED STUDY; EVOKED VISUAL RESPONSE; EXECUTIVE FUNCTION; EYE FIXATION; EYE TRACKING; FEMALE; HIPPOCAMPUS; HUMAN; LONG TERM MEMORY; MALE; NEUROPSYCHOLOGICAL TEST; PATIENT MONITORING; PERCEPTION DISORDER; PERIRHINAL CORTEX; RECALL; RESPONSE TIME; SEMANTICS; TASK PERFORMANCE; TEMPORAL LOBE; VISUAL DISCRIMINATION; VISUAL MEMORY; VISUAL STIMULATION; WORKING MEMORY;

AGED; AMNESIA; BRAIN INJURIES; FACE; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; OCULAR MOTILITY DISORDERS; PATTERN RECOGNITION, VISUAL; PERCEPTUAL DISORDERS; PHOTIC STIMULATION; REACTION TIME; RECOGNITION (PSYCHOLOGY); TEMPORAL LOBE; TIME FACTORS;

EID: 84871382033     PISSN: 00283932     EISSN: 18733514     Source Type: Journal    
DOI: 10.1016/j.neuropsychologia.2012.11.003     Document Type: Article

References (80)

1. Adlam A.L.R., Patterson K., Bozeat S., Hodges J.R. The Cambridge Semantic Memory Test Battery: Detection of semantic deficits in semantic dementia and Alzheimer's disease. Neurocase 2010, 16(3):193-207.
2. Althoff R.R., Cohen N.J. Eye-movement-based memory effect: A reprocessing effect in face perception. Journal of Experimental Psychology: Learning Memory and Cognition 1999, 25(4):997-1010.
3. Barense M.D., Bussey T.J., Lee A.C.H., Rogers T.T., Davies R.R., Saksida L.M., et al. Functional specialization in the human medial temporal lobe. The Journal of Neuroscience 2005, 25(44):10239-10246.
4. Barense M.D., Gaffan, Graham K.S. The human medial temporal lobe processes online representations of complex objects. Neuropsychologia 2007, 45(13):2963-2974.
5. Barense M.D., Henson R.N.a, Lee A.C.H., Graham K.S. Medial temporal lobe activity during complex discrimination of faces, objects, and scenes: Effects of viewpoint. Hippocampus 2010, 20(3):389-401.
6. Barense M.D., Rogers T.T., Bussey T.J., Saksida L.M., Graham K.S. Influence of conceptual knowledge on visual object discrimination: Semantic dementia and MTL amnesia. Cerebral Cortex 2010, 20(11):2568-2582.
7. Barense M.D., Henson R.N.A., Graham K.S. Perception and conception: Temporal lobe activity during complex discriminations of familiar and novel faces and objects. Journal of Cognitive Neuroscience 2011, 23(10):3052-3067.
8. Barense M.D., Ngo J.K.W., Hung L.H.T., Peterson M.A. Interactions of memory and perception in amnesia: The figure-ground perspective. Cerebral Cortex 2012, 22(11):2680-2691.
9. Barense M., Groen I., Lee A., Yeung L., Brady S., Gregori M., et al. Intact memory for irrelevant information impairs perception in amnesia. Neuron 2012, 75:157-167.
10. Bartko S.J., Winters B.D., Cowell R.A., Saksida L.M., Bussey T.J. Perirhinal cortex resolves feature ambiguity in configural object recognition and perceptual oddity tasks. Learning and Memory 2007, 14(12):821-832.
11. Benton A.L., Sivan A.B., Hamsher K.d.S, Varney N.R., Spreen O. Facial recognition stimulus and multiple choice pictures 1994, Oxford University Press, New York.
12. Bird C.M., Chan D., Hartley T., Pijnenburg Y.a, Rossor M.N., Burgess N. Topographical short-term memory differentiates Alzheimer's disease from frontotemporal lobar degeneration. Hippocampus 2010, 20(10):1154-1169.
13. Buckley M.J., Booth M.C., Rolls E.T., Gaffan D. Selective perceptual impairments after perirhinal cortex ablation. The Journal of Neuroscience 2001, 21(24):9824-9836.
14. Bussey T.J., Saksida L.M. Memory, perception, and the ventral visual-perirhinal-hippocampal stream: Thinking outside of the boxes. Hippocampus 2007, 908:898-908.
15. Bussey T.J., Saksida L.M., Murray Perirhinal cortex resolves feature ambiguity in complex visual discriminations. The European Journal of Neuroscience 2002, 15(2):365-374.
16. Bussey T.J., Saksida L.M., Murray E.A. Impairments in visual discrimination after perirhinal cortex lesions: Testing "declarative" vs. "perceptual-mnemonic" views of perirhinal cortex function. European Journal of Neuroscience 2003, 17:649-660.
17. Cashdollar N., Malecki U., Rugg-Gunn F.J., Duncan J.S., Lavie N., Duzel E. Hippocampus-dependent and -independent theta-networks of active maintenance. Proceedings of the National Academy of Sciences 2009, 106(48):20493-20498.
18. Clark R.E., Reinagel P., Broadbent N.J., Flister E.D., Squire L.R. Intact performance on feature-ambiguous discriminations in rats with lesions of the perirhinal cortex. Neuron 2011, 70(1):132-140.
19. Cohen N.J., Eichenbaum H. Memory, amnesia, and the hippocampal system 1993, MIT, Cambridge, MA.
20. Cowell R.A., Bussey T.J., Saksida L.M. Why does brain damage impair memory? A connectionist model of object recognition memory in perirhinal cortex. The Journal of Neuroscience 2006, 26(47):12186-12197.
21. Cowell R.A., Bussey T.J., Saksida L.M. Functional dissociations within the ventral object processing pathway: Cognitive modules or a hierarchical continuum?. The Journal of Cognitive Neuroscience 2010, 22(11):2460-2479.
22. Crawford J.R., Howell D.C. Comparing an individual's test score against norms derived from small samples. The Clinical Neuropsychologist (Neuropsychology, Development and Cognition: Section D) 1998, 12(4):482-486.
23. Devlin J.T., Price C.J. Perirhinal contributions to human visual perception. Current Biology 2007, 17(17):1484-1488.
24. Diana R.a, Yonelinas A.P., Ranganath C. Imaging recollection and familiarity in the medial temporal lobe: A three-component model. Trends in Cognitive Sciences 2007, 11(9):379-386.
25. Eichenbaum H., Cohen N.J. From conditioning to conscious recollection: Memory systems of the brain 2001, Oxford University Press, New York.
26. Gajewski D.A., Henderson J.M. Minimal use of working memory in a scene comparison task. Visual Cognition 2005, 12(6):979-1002.
27. Gauthier I., Tarr M.J. Becoming a "Greeble" expert: Exploring mechanisms for face recognition. Vision Research 1997, 37(12):1673-1682.
28. Graham N.L., Emery T., Hodges J.R. Distinctive cognitive profiles in Alzheimer's disease and subcortical vascular dementia. Journal of Neurology Neurosurgery & Psychiatry 2004, 75(1):61-71.
29. Graham K.S., Barense M.D., Lee A.C.H. Going beyond LTM in the MTL: A synthesis of neuropsychological and neuroimaging findings on the role of the medial temporal lobe in memory and perception. Neuropsychologia 2010, 48(4):831-853.
30. Graham K.S., Scahill V.L., Hornberger M., Barense M.D., Lee A.C.H., Bussey T.J., et al. Abnormal categorization and perceptual learning in patients with hippocampal damage. The Journal of Neuroscience 2006, 26(29):7547-7554.
31. Haaland K.Y., Price L., Larue A. What does the WMS-III tell us about memory changes with normal aging?. Journal of the International Neuropsychological Society 2003, 9(1):89-96.
32. Hannula D.E., Tranel D., Cohen N.J. The long and the short of it: Relational memory impairments in amnesia, even at short lags. The Journal of Neuroscience 2006, 26(32):8352-8359.
33. Hannula D.E., Ryan J.D., Tranel D., Cohen N.J. Rapid onset relational memory effects are evident in eye movement behavior, but not in hippocampal amnesia. Journal of Cognitive Neuroscience 2007, 19:1690-1705.
34. Hannula D.E., Ranganath C. Medial temporal lobe activity predicts successful relational memory binding. The Journal of Neuroscience 2008, 28(1):116-124.
35. Hannula D.E., Ranganath C. The eyes have it: Hippocampal activity predicts expression of memory in eye movements. Neuron 2009, 63(5):592-599.
36. Hannula D.E., Althoff R.R., Warren D.E., Riggs L., Cohen N.J., Ryan J.D. Worth a glance: Using eye movements to investigate the cognitive neuroscience of memory. Frontiers in Human Neuroscience 2010, 4(166):1-17.
37. Henderson J.M., Anes M.D. Roles of object-file review and type priming in visual identification within and across eye fixations. Journal of Experimental Psychology: Human Perception and Performance 1994, 20(4):826-839.
38. Hodges J.R., Patterson K. Is semantic memory consistently impaired early in the course of Alzheimer's disease? Neuroanatomical and diagnostic implications. Neuropsychologia 1995, 33(4):441-459.
39. Hollingworth A., Richard A.M., Luck S.J. Understanding the function of visual short-term memory: Transsaccadic memory, object correspondence, and gaze correction. Journal of Experimental Psychology: General 2008, 137(1):163-181.
40. Howard D., Patterson K. Pyramids and palm trees: A test of semantic access from pictures and words 1992, Bury St. Edmunds, England: Thames Valley Test.
41. Insausti R., Juottonen K., Soininen H., Insausti A.M., Partanen K., Vainio P., et al. MR volumetric analysis of the human entorhinal, perirhinal, and temporopolar cortices. AJNR American Journal of Neuroradiology 1998, 19:659-671.
42. Irwin D.E. Memory for position and identity across eye movements. Journal of Experimental Psychology: Learning, Memory, and Cognition 1992, 18(2):307-317.
43. Kim S., Jeneson A., van der Horst A.S., Frascino J.C., Hopkins R.O., Squire L.R. Memory, visual discrimination performance, and the human hippocampus. The Journal of Neuroscience 2011, 31(7):2624-2629.
44. Kowler E. Eye movements: The past 25years. Vision Research 2011, 51(13):1457-1483.
45. Lee A.C.H., Rudebeck S.R. Human medial temporal lobe damage can disrupt the perception of single objects. The Journal of Neuroscience 2010, 30(19):6588-6594.
46. Lee A.C.H., Rudebeck S.R. Investigating the interaction between spatial perception and working memory in the human medial temporal lobe. Journal of Cognitive Neuroscience 2010, 22(12):2823-2835.
47. Lee A.C.H., Buckley Mark J., Pegman S.J., Spiers H., Scahill V.L., Gaffan, et al. Specialization in the medial temporal lobe for processing of objects and scenes. Hippocampus 2005, 15(6):782-797.
48. Lee A.C.H., Bussey T.J., Murray E.a, Saksida L.M., Epstein R.a, Kapur N., et al. Perceptual deficits in amnesia: Challenging the medial temporal lobe "mnemonic" view. Neuropsychologia 2005, 43(1):1-11.
49. Lee A.C.H., Buckley Mark J., Gaffan, David Emery, T., Hodges J.R., Graham K.S. Differentiating the roles of the hippocampus and perirhinal cortex in processes beyond long-term declarative memory: A double dissociation in dementia. The Journal of Neuroscience 2006, 26(19):5198-5203.
50. Lee A.C.H., Scahill V.L., Graham K.S. Activating the medial temporal lobe during oddity judgment for faces and scenes. Cerebral Cortex 2008, 18(3):683-696.
51. Nelson H.E. A modified card sorting test sensitive to frontal lobe defects. Cortex 1976, 12(4):313-324.
52. Newsome R.N., Duarte A., Barense M.D. Reducing perceptual interference improves visual discrimination in mild cognitive impairment: Implications for a model of perirhinal cortex function. Hippocampus 2012, 22:1990-1999.
53. Nichols E.A., Kao Y-ching, Verfaellie M., Gabrieli J.D.E. Working memory and long-term memory for faces: Evidence from fMRI and global amnesia for involvement of the medial temporal lobes. Hippocampus 2006, 616:604-616.
54. Olson I.R., Page K., Moore K.S., Chatterjee A., Verfaellie M. Working memory for conjunctions relies on the medial temporal lobe. The Journal of Neuroscience 2006, 26(17):4596-4601.
55. Olson I.R., Moore K.S., Stark M., Chatterjee A. Visual working memory is impaired when the medial temporal lobe is damaged. Journal of Cognitive Neuroscience 2006, 18(7):1087-1097.
56. O'Neil E.B., Cate A.D., Köhler S. Perirhinal cortex contributes to accuracy in recognition memory and perceptual discriminations. The Journal of Neuroscience 2009, 29(26):8329-8334.
57. Osterrieth P.A. Le test de copie d'une figure complexe. Archives de Psychologie 1944, 30:205-220.
58. Peterson M.A., Cacciamani L., Barense M.D., Scalf P.E. The perirhinal cortex modulates V2 activity in response to agreement between part familiarity and configuration familiarity. Hippocampus 2012, 22:1965-1977.
59. Ranganath C., D'Esposito M. Medial temporal lobe activity associated with active maintenance of novel information. Neuron 2001, 31:865-873.
60. Ranganath C., Blumenfeld R.S. Doubts about double dissociations between short- and long-term memory. Trends in Cognitive Sciences 2005, 9:374-380.
61. Raven J.C. Coloured progressive matrices sets A, AB, B 1962, H.K. Lewis, London.
62. Rorden C., Brett M. Stereotaxic display of brain lesions. Behavioural Neurology 2000, 12(4):191-200.
63. Rudebeck S.R., Filippini N., Lee A.C.H. Can complex visual discrimination deficits in amnesia be attributed to the medial temporal lobe? An investigation into the effects of medial temporal lobe damage on brain connectivity. Hippocampus 2012, 10.1002/hipo.22056.
64. Ryan J.D., Althoff R.R., Whitlow S., Cohen N.J. Amnesia is a deficit in relational memory. Psychological Science 2000, 11(6):454-461.
65. Ryan L., Cox C., Hayes S.M., Nadel L. Hippocampal activation during episodic and semantic memory retrieval: Comparing category production and category cued recall. Neuropsychologia 2008, 46(8):2109-2121.
66. Ryan L., Lin C.-Y., Ketcham K., Nadel L. The role of medial temporal lobe in retrieving spatial and nonspatial relations from episodic and semantic memory. Hippocampus 2010, 20(1):11-18.
67. Saksida L.M., Bussey T.J. The representational-hierarchical view of amnesia: Translation from animal to human. Neuropsychologia 2010, 48(8):2370-2384.
68. Schon K., Quiroz Y.T., Hasselmo M.E., Stern C.E. Greater working memory load results in greater medial temporal activity at retrieval. Cerebral Cortex (New York, N.Y.: 1991) 2009, 19(11):2561-2571.
69. Squire L.R., Wixted J.T. The cognitive neuroscience of human memory since H.M. Annual Review of Neuroscience 2011, 259-290.
70. Stern C.E., Sherman S.J., Kirchhoff B.A., Hasselmo M.E. Medial temporal and prefrontal contributions to working memory tasks with novel and familiar stimuli. Hippocampus 2001, 11:337-346.
71. Taylor K.J., Henson R.N.A., Graham K.S. Recognition memory for faces and scenes in amnesia: Dissociable roles of medial temporal lobe structures. Neuropsychologia 2007, 45(11):2428-2438.
72. Toepper M., Markowitsch H.J., Gebhardt H., Beblo T., Thomas C., Gallhofer B., et al. Hippocampal involvement in working memory encoding of changing locations: An fMRI study. Brain Research 2010, 1354:91-99.
73. Van der Stigchel S., Meeter M., Theeuwes J. Eye movement trajectories and what they tell us. Neuroscience and Biobehavioral Reviews 2006, 30(5):666-679.
74. Warren D.E., Duff M.C., Tranel D., Cohen N.J. Medial temporal lobe damage impairs representation of simple stimuli. Frontiers in Human Neuroscience 2010, 4(May):35.
75. Warren D.E., Duff M.C., Tranel D., Cohen N.J. Observing degradation of visual representations over short intervals when medial temporal lobe is damaged. Journal of Cognitive Neuroscience 2011, 23(12):3862-3873.
76. Warren D.E., Duff M.C., Jensen U., Tranel D., Cohen N.J. Hiding in plain view: Lesions of the medial temporal lobe impair online representation. Hippocampus 2011, 10.1002/hipo.21000.
77. Warrington E.K. The recognition memory test 1984, Windsor: NFER-Nelson.
78. Warrington E.K., James M. Visual object and space perception battery (VOSP) 1991, Harcourt Assessment, Oxford.
79. Watson C., Jack C.R., Cendes F. Volumetric magnetic resonance imaging. Clinical applications and contributions to the understanding of temporal lobe epilepsy. Archives of Neurology 1997, 54:1521-1531.
80. Wechsler D. Wechsler memory scale 1997, (3rd ed.). San Antonio, TX: Psychological Corp.