-
2
-
-
0027292723
-
Screening for lung cancer. The Mayo Lung Project revisited
-
Flehinger BJ, Kimmel M, Polyak T and Melamed MR: Screening for lung cancer. The Mayo Lung Project revisited. Cancer 72: 1573-1580, 1993.
-
(1993)
Cancer
, vol.72
, pp. 1573-1580
-
-
Flehinger, B.J.1
Kimmel, M.2
Polyak, T.3
Melamed, M.R.4
-
3
-
-
0030870266
-
Measuring effectiveness of lung cancer screening: From concensus to controversy and back
-
Strauss GM: Measuring effectiveness of lung cancer screening: from concensus to controversy and back. Chest 112 (Suppl 4): 216S-228S, 1997.
-
(1997)
Chest
, vol.112
, Issue.SUPPL. 4
-
-
Strauss, G.M.1
-
4
-
-
0032602576
-
Is there a genetic basis for lung cancer susceptibility
-
Amos CI, Xu W and Spitz MR: Is there a genetic basis for lung cancer susceptibility? Recent Results Cancer Res 151: 3-12, 1999.
-
(1999)
Recent Results Cancer Res
, vol.151
, pp. 3-12
-
-
Amos, C.I.1
Xu, W.2
Spitz, M.R.3
-
6
-
-
0034616665
-
Somatic mutation screening: Identification of individuals harboring K-Ras mutations with the use of plasma DNA
-
Kopreski MS, Benko FA, Borys DJ, Khan A, McGarrity TJ and Gocke CD: Somatic mutation screening: identification of individuals harboring K-Ras mutations with the use of plasma DNA. J Natl Cancer Inst 92: 918-923, 2000.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 918-923
-
-
Kopreski, M.S.1
Benko, F.A.2
Borys, D.J.3
Khan, A.4
McGarrity, T.J.5
Gocke, C.D.6
-
8
-
-
10844231985
-
Mutations of the Epidermal Growth Factor Receptor gene in lung cancer: Biological and clinical implications
-
Kosaka T, Yatabe Y, Endoh H, Kuwano H, Takahashi T and Mitsudomi T: Mutations of the Epidermal Growth Factor Receptor gene in lung cancer: Biological and clinical implications. Cancer Res 64: 8919-8923, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 8919-8923
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
Kuwano, H.4
Takahashi, T.5
Mitsudomi, T.6
-
9
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
Shigematsu H, Lin L, Takahashi T, Nomura M, Suzuki M, Wistuba II, Fong KM, et al: Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 97: 339-346, 2005.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
Nomura, M.4
Suzuki, M.5
Wistuba, I.I.6
Fong, K.M.7
-
10
-
-
50849094202
-
Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: A chromogenic in situ hybridization study of 182 patients
-
Chang JW, Liu HP, Hsieh MH, Fang YF, Hsieh MS, Hsieh JJ, Chiu YT, et al: Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: a chromogenic in situ hybridization study of 182 patients. Lung Cancer 61: 328-339, 2008.
-
(2008)
Lung Cancer
, vol.61
, pp. 328-339
-
-
Chang, J.W.1
Liu, H.P.2
Hsieh, M.H.3
Fang, Y.F.4
Hsieh, M.S.5
Hsieh, J.J.6
Chiu, Y.T.7
-
11
-
-
41049086345
-
Epidermal growth factor gene amplification and gefitinib sensitivity in patients with recurrent lung cancer
-
Sasaki H, Endo K, Okuda K, Kawano O, Kitahara N, Tanaka H, Matsumura A, et al: Epidermal growth factor gene amplification and gefitinib sensitivity in patients with recurrent lung cancer. JCancer Res Clin Oncol 134: 569-577, 2008.
-
(2008)
JCancer Res Clin Oncol
, vol.134
, pp. 569-577
-
-
Sasaki, H.1
Endo, K.2
Okuda, K.3
Kawano, O.4
Kitahara, N.5
Tanaka, H.6
Matsumura, A.7
-
12
-
-
33750700477
-
Erlotinib for frontline treatment of advanced non-small cell lung cancer: A phase II study
-
Giaccone G, Gallegos Ruiz M, Le Chevalier T, Thatcher N, SmitE, Rodriguez JA, Janne P, et al: Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study. Clin Cancer Res 12: 6049-6055, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6049-6055
-
-
Giaccone, G.1
Gallegos Ruiz, M.2
Le Chevalier, T.3
Thatcher, N.4
Smit, E.5
Rodriguez, J.A.6
Janne, P.7
-
13
-
-
0024376173
-
ras oncogenes in human cancer: A review
-
Bos JL: ras oncogenes in human cancer: a review. Cancer Res. 49: 4682-4689, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
14
-
-
34047248571
-
Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
-
Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, Zanon C, Moroni M, Veronese S, Siena S and Bardelli A: Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res 67: 2643-2648, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 2643-2648
-
-
Benvenuti, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
Zanon, C.4
Moroni, M.5
Veronese, S.6
Siena, S.7
Bardelli, A.8
-
16
-
-
52749099497
-
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
Linardou H, Dahabreh IJ, Kanaloupiti D, Siannis F, BafaloukosD, Kosmidis P, Papadimitriou CA and Murray S: Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol 9: 962-972, 2008.
-
(2008)
Lancet Oncol
, vol.9
, pp. 962-972
-
-
Linardou, H.1
Dahabreh, I.J.2
Kanaloupiti, D.3
Siannis, F.4
Bafaloukos, D.5
Kosmidis, P.6
Papadimitriou, C.A.7
Murray, S.8
-
17
-
-
67349280633
-
Epidermal growth factor receptor gene amplification in surgical resected Japanese lung cancer
-
Sasaki H, Shimizu S, Okuda K, Kawano O, Yukiue H, Yano M and Fujii Y: Epidermal growth factor receptor gene amplification in surgical resected Japanese lung cancer. Lung Cancer 64: 295-300, 2009.
-
(2009)
Lung Cancer
, vol.64
, pp. 295-300
-
-
Sasaki, H.1
Shimizu, S.2
Okuda, K.3
Kawano, O.4
Yukiue, H.5
Yano, M.6
Fujii, Y.7
-
18
-
-
15744372810
-
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
-
Pao W, Wang TY, Riely GJ, Miller VA, Pan Q, Ladanyi M, Zakowski MF, et al: KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2: e17, 2005.
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Wang, T.Y.2
Riely, G.J.3
Miller, V.A.4
Pan, Q.5
Ladanyi, M.6
Zakowski, M.F.7
-
19
-
-
0026471016
-
Prognostic markers of colorectal cancer: An evaluation of DNA content, epidermal growth factor receptor, and Ki-67
-
Hemming AW, Davis NL, Kluftinger A, Robinson B, QuenvilleNF, Liseman B and LeRiche J: Prognostic markers of colorectal cancer: an evaluation of DNA content, epidermal growth factor receptor, and Ki-67. J Surg Oncol 51: 147-152, 1992.
-
(1992)
J Surg Oncol
, vol.51
, pp. 147-152
-
-
Hemming, A.W.1
Davis, N.L.2
Kluftinger, A.3
Robinson, B.4
Quenville, N.F.5
Liseman, B.6
LeRiche, J.7
-
20
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, Doherty J, Politi K, Sarkaria I, Singh B, et al: EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 101: 13306-13311, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
Sarkaria, I.6
Singh, B.7
-
21
-
-
0027159063
-
Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
-
Rusch V, Baselga J, Cordon-Cardo C, Orazem J, Zaman M, HodaS, McIntosh J, et al: Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 53 (Suppl 10): 2379-2385, 1993.
-
(1993)
Cancer Res
, vol.53
, Issue.SUPPL. 10
, pp. 2379-2385
-
-
Rusch, V.1
Baselga, J.2
Cordon-Cardo, C.3
Orazem, J.4
Zaman, M.5
Hoda, S.6
McIntosh, J.7
-
22
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello F and Tortora G: EGFR antagonists in cancer treatment. N Engl J Med 358: 1160-1174, 2008.
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
23
-
-
20444480258
-
TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: Distinct patterns in never, former, and current smokers
-
Le Calvez F, Mukeria A, Hunt JD, Kelm O, Hung RJ, TanièreP, Brennan P, Boffetta P, et al: TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers. Cancer Res 65: 5076-5083, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 5076-5083
-
-
Le Calvez, F.1
Mukeria, A.2
Hunt, J.D.3
Kelm, O.4
Hung, R.J.5
Tanière, P.6
Brennan, P.7
Boffetta, P.8
-
24
-
-
33645052711
-
Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features
-
Tam IY, Chung LP, Suen WS, Wang E, Wong MC, Ho KK, LamWK, et al: Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features. Clin Cancer Res 12: 1647-1653, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1647-1653
-
-
Tam, I.Y.1
Chung, L.P.2
Suen, W.S.3
Wang, E.4
Wong, M.C.5
Ho, K.K.6
Lam, W.K.7
-
25
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, et al: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350: 2129-2139, 2004.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
-
26
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, Gabriel S, Herman P, et al: EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304: 1497-1500, 2004.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
-
27
-
-
33645290760
-
Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking
-
Sugio K, Uramoto H, Ono K, Oyama T, Hanagiri T, Sugaya M, Ichiki M, et al: Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking. Br J Cancer 94: 896-903, 2006.
-
(2006)
Br J Cancer
, vol.94
, pp. 896-903
-
-
Sugio, K.1
Uramoto, H.2
Ono, K.3
Oyama, T.4
Hanagiri, T.5
Sugaya, M.6
Ichiki, M.7
-
28
-
-
19944433797
-
The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers
-
Tokumo M, Toyooka S, Kiura K, Shigematsu H, Tomii K, AoeM, Ichimura K, et al: The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers. Clin Cancer Res 11: 1167-1173, 2005.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1167-1173
-
-
Tokumo, M.1
Toyooka, S.2
Kiura, K.3
Shigematsu, H.4
Tomii, K.5
Aoe, M.6
Ichimura, K.7
-
29
-
-
33645805630
-
Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas
-
Pham D, Kris MG, Riely GJ, Sarkaria IS, McDonough T, ChuaiS, Venkatraman ES, et al: Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas. J Clin Oncol 24: 1700-1704, 2006.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1700-1704
-
-
Pham, D.1
Kris, M.G.2
Riely, G.J.3
Sarkaria, I.S.4
McDonough, T.5
Chuai, S.6
Venkatraman, E.S.7
-
30
-
-
78649316766
-
Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer
-
Lee YJ, Shim HS, Kang YA, Hong SJ, Kim HK, Kim H, Kim SK, et al: Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer. J Cancer Res Clin Oncol 136: 1937-1944, 2010.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 1937-1944
-
-
Lee, Y.J.1
Shim, H.S.2
Kang, Y.A.3
Hong, S.J.4
Kim, H.K.5
Kim, H.6
Kim, S.K.7
-
31
-
-
20244388126
-
Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence
-
Mitsudomi T, Kosaka T, Endoh H, Horio Y, Hida T, Mori S, et al: Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol 23: 2513-2520, 2005.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2513-2520
-
-
Mitsudomi, T.1
Kosaka, T.2
Endoh, H.3
Horio, Y.4
Hida, T.5
Mori, S.6
-
32
-
-
0033739215
-
Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: A population-based study
-
Samowitz WS, Curtin K, Schaffer D, Robertson M, Leppert M and Slattery ML: Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study. Cancer Epidemiol Biomarkers Prev 9: 1193-1197, 2000.
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 1193-1197
-
-
Samowitz, W.S.1
Curtin, K.2
Schaffer, D.3
Robertson, M.4
Leppert, M.5
Slattery, M.L.6
-
33
-
-
33846640734
-
Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium
-
Keller JW, Franklin JL, Graves-Deal R, Friedman DB, WhitwellCW and Coffey RJ: Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium. J Cell Physiol210: 740-749, 2007.
-
(2007)
J Cell Physiol
, vol.210
, pp. 740-749
-
-
Keller, J.W.1
Franklin, J.L.2
Graves-Deal, R.3
Friedman, D.B.4
Whitwell, C.W.5
Coffey, R.J.6
-
34
-
-
38349029100
-
Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: Correlation to activated K-Ras oncogene
-
Wang JY, Wang YH, Jao SW, Lu CY, Kuo CH, Hu HM, HsiehJS, et al: Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: correlation to activated K-Ras oncogene. Oncol Rep 16: 1245-1252, 2006.
-
(2006)
Oncol Rep
, vol.16
, pp. 1245-1252
-
-
Wang, J.Y.1
Wang, Y.H.2
Jao, S.W.3
Lu, C.Y.4
Kuo, C.H.5
Hu, H.M.6
Hsieh, J.S.7
-
35
-
-
0037152628
-
Tobacco smoke carcinogenesis, DNA damage and p53 mutations in smoking-associated cancers
-
Pfeifer GP, Denissenko MF, Olivier M, Tretyakova N, Hecht SS and Hainaut P: Tobacco smoke carcinogenesis, DNA damage and p53 mutations in smoking-associated cancers. Oncogene 21: 7435-7451, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 7435-7451
-
-
Pfeifer, G.P.1
Denissenko, M.F.2
Olivier, M.3
Tretyakova, N.4
Hecht, S.S.5
Hainaut, P.6
-
36
-
-
77953133384
-
Oncogenic mutant forms of EGFR: Lessons in signal transduction and targets for cancer therapy
-
Pines G, Köstler WJ and Yarden Y: Oncogenic mutant forms of EGFR: lessons in signal transduction and targets for cancer therapy. FEBS Lett 584: 2699-2706, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 2699-2706
-
-
Pines, G.1
Köstler, W.J.2
Yarden, Y.3
-
37
-
-
68049088934
-
EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases
-
Schmid K, Oehl N, Wrba F, Pirker R, Pirker C and Filipits M: EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases. Clin Cancer Res 15: 4554-4560, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4554-4560
-
-
Schmid, K.1
Oehl, N.2
Wrba, F.3
Pirker, R.4
Pirker, C.5
Filipits, M.6
-
38
-
-
33646418681
-
Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-Ras mutation, and Akt phosphorylation
-
Han SW, Kim TY, Jeon YK, Hwang PG, Im SA, Lee KH, KimJH, et al: Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-Ras mutation, and Akt phosphorylation. Clin Cancer Res 12: 2538-2544, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2538-2544
-
-
Han, S.W.1
Kim, T.Y.2
Jeon, Y.K.3
Hwang, P.G.4
Im, S.A.5
Lee, K.H.6
Kim, J.H.7
-
39
-
-
33846483745
-
EGFR and KRAS mutations as criteria for treatment with tyrosine kinase inhibitors: Retro-and prospective observations in non-small-cell lung cancer
-
van Zandwijk N, Mathy A, Boerrigter L, Ruijter H, TielenI, deJong D, Baas P, et al: EGFR and KRAS mutations as criteria for treatment with tyrosine kinase inhibitors: retro-and prospective observations in non-small-cell lung cancer. Ann Oncol 18: 99-103, 2007.
-
(2007)
Ann Oncol
, vol.18
, pp. 99-103
-
-
van Zandwijk, N.1
Mathy, A.2
Boerrigter, L.3
Ruijter, H.4
Tielen, I.5
deJong, D.6
Baas, P.7
-
40
-
-
34249810645
-
KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Massarelli E, Varella-Garcia M, Tang X, Xavier AC, OzburnNC, Liu DD, Bekele BN, et al: KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin Cancer Res 13: 2890-2896, 2007.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2890-2896
-
-
Massarelli, E.1
Varella-Garcia, M.2
Tang, X.3
Xavier, A.C.4
Ozburn, N.C.5
Liu, D.D.6
Bekele, B.N.7
-
41
-
-
40549100029
-
siRNA targeting against EGFR, a promising candidate for a novel therapeutic application to lung adenocarcinoma
-
Yamanaka S, Gu Z, Sato M, Fujisaki R, Inomata K, SakuradaA, Inoue A, et al: siRNA targeting against EGFR, a promising candidate for a novel therapeutic application to lung adenocarcinoma. Pathobiology 75: 2-8, 2008.
-
(2008)
Pathobiology
, vol.75
, pp. 2-8
-
-
Yamanaka, S.1
Gu, Z.2
Sato, M.3
Fujisaki, R.4
Inomata, K.5
Sakurada, A.6
Inoue, A.7
|