메뉴 건너뛰기




Volumn 5, Issue 2, 2013, Pages 495-498

Association of epidermal growth factor receptor and K-Ras mutations with smoking history in non-small cell lung cancer patients

Author keywords

Epidermal growth factor receptor; K Ras; Non small cell lung cancer; Smoking

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GUANOSINE TRIPHOSPHATASE; K RAS PROTEIN;

EID: 84871357100     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2012.829     Document Type: Article
Times cited : (13)

References (41)
  • 1
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: Globocan 2000
    • Parkin DM, Bray F, Ferlay J and Pisani P: Estimating the world cancer burden: Globocan 2000. Int J Cancer 94: 153-156, 2001.
    • (2001) Int J Cancer , vol.94 , pp. 153-156
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 2
    • 0027292723 scopus 로고
    • Screening for lung cancer. The Mayo Lung Project revisited
    • Flehinger BJ, Kimmel M, Polyak T and Melamed MR: Screening for lung cancer. The Mayo Lung Project revisited. Cancer 72: 1573-1580, 1993.
    • (1993) Cancer , vol.72 , pp. 1573-1580
    • Flehinger, B.J.1    Kimmel, M.2    Polyak, T.3    Melamed, M.R.4
  • 3
    • 0030870266 scopus 로고    scopus 로고
    • Measuring effectiveness of lung cancer screening: From concensus to controversy and back
    • Strauss GM: Measuring effectiveness of lung cancer screening: from concensus to controversy and back. Chest 112 (Suppl 4): 216S-228S, 1997.
    • (1997) Chest , vol.112 , Issue.SUPPL. 4
    • Strauss, G.M.1
  • 4
    • 0032602576 scopus 로고    scopus 로고
    • Is there a genetic basis for lung cancer susceptibility
    • Amos CI, Xu W and Spitz MR: Is there a genetic basis for lung cancer susceptibility? Recent Results Cancer Res 151: 3-12, 1999.
    • (1999) Recent Results Cancer Res , vol.151 , pp. 3-12
    • Amos, C.I.1    Xu, W.2    Spitz, M.R.3
  • 6
    • 0034616665 scopus 로고    scopus 로고
    • Somatic mutation screening: Identification of individuals harboring K-Ras mutations with the use of plasma DNA
    • Kopreski MS, Benko FA, Borys DJ, Khan A, McGarrity TJ and Gocke CD: Somatic mutation screening: identification of individuals harboring K-Ras mutations with the use of plasma DNA. J Natl Cancer Inst 92: 918-923, 2000.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 918-923
    • Kopreski, M.S.1    Benko, F.A.2    Borys, D.J.3    Khan, A.4    McGarrity, T.J.5    Gocke, C.D.6
  • 8
    • 10844231985 scopus 로고    scopus 로고
    • Mutations of the Epidermal Growth Factor Receptor gene in lung cancer: Biological and clinical implications
    • Kosaka T, Yatabe Y, Endoh H, Kuwano H, Takahashi T and Mitsudomi T: Mutations of the Epidermal Growth Factor Receptor gene in lung cancer: Biological and clinical implications. Cancer Res 64: 8919-8923, 2004.
    • (2004) Cancer Res , vol.64 , pp. 8919-8923
    • Kosaka, T.1    Yatabe, Y.2    Endoh, H.3    Kuwano, H.4    Takahashi, T.5    Mitsudomi, T.6
  • 9
    • 20044364940 scopus 로고    scopus 로고
    • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
    • Shigematsu H, Lin L, Takahashi T, Nomura M, Suzuki M, Wistuba II, Fong KM, et al: Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 97: 339-346, 2005.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 339-346
    • Shigematsu, H.1    Lin, L.2    Takahashi, T.3    Nomura, M.4    Suzuki, M.5    Wistuba, I.I.6    Fong, K.M.7
  • 10
    • 50849094202 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: A chromogenic in situ hybridization study of 182 patients
    • Chang JW, Liu HP, Hsieh MH, Fang YF, Hsieh MS, Hsieh JJ, Chiu YT, et al: Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: a chromogenic in situ hybridization study of 182 patients. Lung Cancer 61: 328-339, 2008.
    • (2008) Lung Cancer , vol.61 , pp. 328-339
    • Chang, J.W.1    Liu, H.P.2    Hsieh, M.H.3    Fang, Y.F.4    Hsieh, M.S.5    Hsieh, J.J.6    Chiu, Y.T.7
  • 11
    • 41049086345 scopus 로고    scopus 로고
    • Epidermal growth factor gene amplification and gefitinib sensitivity in patients with recurrent lung cancer
    • Sasaki H, Endo K, Okuda K, Kawano O, Kitahara N, Tanaka H, Matsumura A, et al: Epidermal growth factor gene amplification and gefitinib sensitivity in patients with recurrent lung cancer. JCancer Res Clin Oncol 134: 569-577, 2008.
    • (2008) JCancer Res Clin Oncol , vol.134 , pp. 569-577
    • Sasaki, H.1    Endo, K.2    Okuda, K.3    Kawano, O.4    Kitahara, N.5    Tanaka, H.6    Matsumura, A.7
  • 13
    • 0024376173 scopus 로고
    • ras oncogenes in human cancer: A review
    • Bos JL: ras oncogenes in human cancer: a review. Cancer Res. 49: 4682-4689, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 14
    • 34047248571 scopus 로고    scopus 로고
    • Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
    • Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, Zanon C, Moroni M, Veronese S, Siena S and Bardelli A: Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res 67: 2643-2648, 2007.
    • (2007) Cancer Res , vol.67 , pp. 2643-2648
    • Benvenuti, S.1    Sartore-Bianchi, A.2    Di Nicolantonio, F.3    Zanon, C.4    Moroni, M.5    Veronese, S.6    Siena, S.7    Bardelli, A.8
  • 16
    • 52749099497 scopus 로고    scopus 로고
    • Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
    • Linardou H, Dahabreh IJ, Kanaloupiti D, Siannis F, BafaloukosD, Kosmidis P, Papadimitriou CA and Murray S: Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol 9: 962-972, 2008.
    • (2008) Lancet Oncol , vol.9 , pp. 962-972
    • Linardou, H.1    Dahabreh, I.J.2    Kanaloupiti, D.3    Siannis, F.4    Bafaloukos, D.5    Kosmidis, P.6    Papadimitriou, C.A.7    Murray, S.8
  • 17
    • 67349280633 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene amplification in surgical resected Japanese lung cancer
    • Sasaki H, Shimizu S, Okuda K, Kawano O, Yukiue H, Yano M and Fujii Y: Epidermal growth factor receptor gene amplification in surgical resected Japanese lung cancer. Lung Cancer 64: 295-300, 2009.
    • (2009) Lung Cancer , vol.64 , pp. 295-300
    • Sasaki, H.1    Shimizu, S.2    Okuda, K.3    Kawano, O.4    Yukiue, H.5    Yano, M.6    Fujii, Y.7
  • 19
    • 0026471016 scopus 로고
    • Prognostic markers of colorectal cancer: An evaluation of DNA content, epidermal growth factor receptor, and Ki-67
    • Hemming AW, Davis NL, Kluftinger A, Robinson B, QuenvilleNF, Liseman B and LeRiche J: Prognostic markers of colorectal cancer: an evaluation of DNA content, epidermal growth factor receptor, and Ki-67. J Surg Oncol 51: 147-152, 1992.
    • (1992) J Surg Oncol , vol.51 , pp. 147-152
    • Hemming, A.W.1    Davis, N.L.2    Kluftinger, A.3    Robinson, B.4    Quenville, N.F.5    Liseman, B.6    LeRiche, J.7
  • 20
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, Doherty J, Politi K, Sarkaria I, Singh B, et al: EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 101: 13306-13311, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3    Doherty, J.4    Politi, K.5    Sarkaria, I.6    Singh, B.7
  • 21
    • 0027159063 scopus 로고
    • Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
    • Rusch V, Baselga J, Cordon-Cardo C, Orazem J, Zaman M, HodaS, McIntosh J, et al: Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res 53 (Suppl 10): 2379-2385, 1993.
    • (1993) Cancer Res , vol.53 , Issue.SUPPL. 10 , pp. 2379-2385
    • Rusch, V.1    Baselga, J.2    Cordon-Cardo, C.3    Orazem, J.4    Zaman, M.5    Hoda, S.6    McIntosh, J.7
  • 22
    • 40849147041 scopus 로고    scopus 로고
    • EGFR antagonists in cancer treatment
    • Ciardiello F and Tortora G: EGFR antagonists in cancer treatment. N Engl J Med 358: 1160-1174, 2008.
    • (2008) N Engl J Med , vol.358 , pp. 1160-1174
    • Ciardiello, F.1    Tortora, G.2
  • 23
    • 20444480258 scopus 로고    scopus 로고
    • TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: Distinct patterns in never, former, and current smokers
    • Le Calvez F, Mukeria A, Hunt JD, Kelm O, Hung RJ, TanièreP, Brennan P, Boffetta P, et al: TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers. Cancer Res 65: 5076-5083, 2005.
    • (2005) Cancer Res , vol.65 , pp. 5076-5083
    • Le Calvez, F.1    Mukeria, A.2    Hunt, J.D.3    Kelm, O.4    Hung, R.J.5    Tanière, P.6    Brennan, P.7    Boffetta, P.8
  • 24
    • 33645052711 scopus 로고    scopus 로고
    • Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features
    • Tam IY, Chung LP, Suen WS, Wang E, Wong MC, Ho KK, LamWK, et al: Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features. Clin Cancer Res 12: 1647-1653, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 1647-1653
    • Tam, I.Y.1    Chung, L.P.2    Suen, W.S.3    Wang, E.4    Wong, M.C.5    Ho, K.K.6    Lam, W.K.7
  • 25
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, et al: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350: 2129-2139, 2004.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5    Brannigan, B.W.6    Harris, P.L.7
  • 26
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, Gabriel S, Herman P, et al: EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304: 1497-1500, 2004.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Jänne, P.A.2    Lee, J.C.3    Tracy, S.4    Greulich, H.5    Gabriel, S.6    Herman, P.7
  • 27
    • 33645290760 scopus 로고    scopus 로고
    • Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking
    • Sugio K, Uramoto H, Ono K, Oyama T, Hanagiri T, Sugaya M, Ichiki M, et al: Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking. Br J Cancer 94: 896-903, 2006.
    • (2006) Br J Cancer , vol.94 , pp. 896-903
    • Sugio, K.1    Uramoto, H.2    Ono, K.3    Oyama, T.4    Hanagiri, T.5    Sugaya, M.6    Ichiki, M.7
  • 28
    • 19944433797 scopus 로고    scopus 로고
    • The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers
    • Tokumo M, Toyooka S, Kiura K, Shigematsu H, Tomii K, AoeM, Ichimura K, et al: The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers. Clin Cancer Res 11: 1167-1173, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 1167-1173
    • Tokumo, M.1    Toyooka, S.2    Kiura, K.3    Shigematsu, H.4    Tomii, K.5    Aoe, M.6    Ichimura, K.7
  • 29
    • 33645805630 scopus 로고    scopus 로고
    • Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas
    • Pham D, Kris MG, Riely GJ, Sarkaria IS, McDonough T, ChuaiS, Venkatraman ES, et al: Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas. J Clin Oncol 24: 1700-1704, 2006.
    • (2006) J Clin Oncol , vol.24 , pp. 1700-1704
    • Pham, D.1    Kris, M.G.2    Riely, G.J.3    Sarkaria, I.S.4    McDonough, T.5    Chuai, S.6    Venkatraman, E.S.7
  • 30
    • 78649316766 scopus 로고    scopus 로고
    • Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer
    • Lee YJ, Shim HS, Kang YA, Hong SJ, Kim HK, Kim H, Kim SK, et al: Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer. J Cancer Res Clin Oncol 136: 1937-1944, 2010.
    • (2010) J Cancer Res Clin Oncol , vol.136 , pp. 1937-1944
    • Lee, Y.J.1    Shim, H.S.2    Kang, Y.A.3    Hong, S.J.4    Kim, H.K.5    Kim, H.6    Kim, S.K.7
  • 31
    • 20244388126 scopus 로고    scopus 로고
    • Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence
    • Mitsudomi T, Kosaka T, Endoh H, Horio Y, Hida T, Mori S, et al: Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol 23: 2513-2520, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 2513-2520
    • Mitsudomi, T.1    Kosaka, T.2    Endoh, H.3    Horio, Y.4    Hida, T.5    Mori, S.6
  • 33
    • 33846640734 scopus 로고    scopus 로고
    • Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium
    • Keller JW, Franklin JL, Graves-Deal R, Friedman DB, WhitwellCW and Coffey RJ: Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium. J Cell Physiol210: 740-749, 2007.
    • (2007) J Cell Physiol , vol.210 , pp. 740-749
    • Keller, J.W.1    Franklin, J.L.2    Graves-Deal, R.3    Friedman, D.B.4    Whitwell, C.W.5    Coffey, R.J.6
  • 34
    • 38349029100 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: Correlation to activated K-Ras oncogene
    • Wang JY, Wang YH, Jao SW, Lu CY, Kuo CH, Hu HM, HsiehJS, et al: Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: correlation to activated K-Ras oncogene. Oncol Rep 16: 1245-1252, 2006.
    • (2006) Oncol Rep , vol.16 , pp. 1245-1252
    • Wang, J.Y.1    Wang, Y.H.2    Jao, S.W.3    Lu, C.Y.4    Kuo, C.H.5    Hu, H.M.6    Hsieh, J.S.7
  • 35
  • 36
    • 77953133384 scopus 로고    scopus 로고
    • Oncogenic mutant forms of EGFR: Lessons in signal transduction and targets for cancer therapy
    • Pines G, Köstler WJ and Yarden Y: Oncogenic mutant forms of EGFR: lessons in signal transduction and targets for cancer therapy. FEBS Lett 584: 2699-2706, 2010.
    • (2010) FEBS Lett , vol.584 , pp. 2699-2706
    • Pines, G.1    Köstler, W.J.2    Yarden, Y.3
  • 37
    • 68049088934 scopus 로고    scopus 로고
    • EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases
    • Schmid K, Oehl N, Wrba F, Pirker R, Pirker C and Filipits M: EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases. Clin Cancer Res 15: 4554-4560, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 4554-4560
    • Schmid, K.1    Oehl, N.2    Wrba, F.3    Pirker, R.4    Pirker, C.5    Filipits, M.6
  • 38
    • 33646418681 scopus 로고    scopus 로고
    • Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-Ras mutation, and Akt phosphorylation
    • Han SW, Kim TY, Jeon YK, Hwang PG, Im SA, Lee KH, KimJH, et al: Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-Ras mutation, and Akt phosphorylation. Clin Cancer Res 12: 2538-2544, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 2538-2544
    • Han, S.W.1    Kim, T.Y.2    Jeon, Y.K.3    Hwang, P.G.4    Im, S.A.5    Lee, K.H.6    Kim, J.H.7
  • 39
    • 33846483745 scopus 로고    scopus 로고
    • EGFR and KRAS mutations as criteria for treatment with tyrosine kinase inhibitors: Retro-and prospective observations in non-small-cell lung cancer
    • van Zandwijk N, Mathy A, Boerrigter L, Ruijter H, TielenI, deJong D, Baas P, et al: EGFR and KRAS mutations as criteria for treatment with tyrosine kinase inhibitors: retro-and prospective observations in non-small-cell lung cancer. Ann Oncol 18: 99-103, 2007.
    • (2007) Ann Oncol , vol.18 , pp. 99-103
    • van Zandwijk, N.1    Mathy, A.2    Boerrigter, L.3    Ruijter, H.4    Tielen, I.5    deJong, D.6    Baas, P.7
  • 40
    • 34249810645 scopus 로고    scopus 로고
    • KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
    • Massarelli E, Varella-Garcia M, Tang X, Xavier AC, OzburnNC, Liu DD, Bekele BN, et al: KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin Cancer Res 13: 2890-2896, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 2890-2896
    • Massarelli, E.1    Varella-Garcia, M.2    Tang, X.3    Xavier, A.C.4    Ozburn, N.C.5    Liu, D.D.6    Bekele, B.N.7
  • 41
    • 40549100029 scopus 로고    scopus 로고
    • siRNA targeting against EGFR, a promising candidate for a novel therapeutic application to lung adenocarcinoma
    • Yamanaka S, Gu Z, Sato M, Fujisaki R, Inomata K, SakuradaA, Inoue A, et al: siRNA targeting against EGFR, a promising candidate for a novel therapeutic application to lung adenocarcinoma. Pathobiology 75: 2-8, 2008.
    • (2008) Pathobiology , vol.75 , pp. 2-8
    • Yamanaka, S.1    Gu, Z.2    Sato, M.3    Fujisaki, R.4    Inomata, K.5    Sakurada, A.6    Inoue, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.