Using Family-Based Imputation in Genome-Wide Association Studies with Large Complex Pedigrees: The Framingham Heart Study

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Chen, Ming Huei ^a,b,c   Huang, Jie ^c,d   Chen, Wei Min ^e   Larson, Martin G ^b,c,f   Fox, Caroline S ^c,g   Vasan, Ramachandran S ^a,c   Seshadri, Sudha ^a,c   O'Donnell, Christopher J ^c,h   Yang, Qiong ^b,c  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^c FRAMINGHAM HEART STUDY   (United States)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^e UNIVERSITY OF VIRGINIA   (United States)

^f USA   (United States)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

^h MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; URIC ACID;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CHOLESTEROL BLOOD LEVEL; COMPUTER PROGRAM; CONTROLLED STUDY; FAMILY STUDY; FEMALE; FIBRINOGEN BLOOD LEVEL; GENE LOCUS; GENETIC ALGORITHM; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PEDIGREE; PHENOTYPIC VARIATION; PROCESS DEVELOPMENT; SINGLE NUCLEOTIDE POLYMORPHISM; URIC ACID BLOOD LEVEL;

ALGORITHMS; CARDIOVASCULAR DISEASES; FEMALE; GENETIC MARKERS; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPMAP PROJECT; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MODELS, STATISTICAL; PEDIGREE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84871344445     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051589     Document Type: Article

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