Exogenous ubiquitin modulates chronic β-adrenergic receptor-stimulated myocardial remodeling: Role in Akt activity and matrix metalloproteinase expression

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 303, Issue 12, 2012, Pages

  Daniels, Christopher R ^a   Foster, Cerrone R ^a   Yakoob, Sana ^a   Dalal, Suman ^a   Joyner, William L ^a   Singh, Mahipal ^a   Singh, Krishna ^a  

^a East Tennessee State University   (United States)

Author keywords

Apoptosis; Fibroblasts; Fibrosis; Heart; Myocytes; Ubiquitin

Indexed keywords

8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; BETA ADRENERGIC RECEPTOR; GELATINASE A; GELATINASE B; ISOPRENALINE; JANUS KINASE; PROTEIN KINASE B; RECOMBINANT PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; U 6253; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; HEART EJECTION FRACTION; HEART FUNCTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE FIBROSIS; HEART WEIGHT; MORPHOMETRICS; MOUSE; MYOCARDIAL REMODELING; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; FIBROSIS; GLYCOGEN SYNTHASE KINASE 3; MALE; MAP KINASE KINASE 4; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED ICR; MYOCARDIUM; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, ADRENERGIC, BETA; TISSUE INHIBITOR OF METALLOPROTEINASE-2; UBIQUITIN; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84871342201     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00401.2012     Document Type: Article

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