Reengineering the collision coupling and diffusion mode of the A 2A-adenosine receptor: Palmitoylation in helix 8 relieves confinement

Journal of Biological Chemistry

Volumn 287, Issue 50, 2012, Pages 42104-42118

  Keuerleber, Simon ^a   Thurner, Patrick ^a   Gruber, Christian W ^a   Zezula, Jürgen ^a   Freissmuth, Michael ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE RECEPTOR; C TERMINUS; DIFFUSION LIMITS; DIFFUSION MODES; EXPRESSION LEVELS; G PROTEIN; G PROTEIN COUPLED RECEPTORS; LIPID RAFT; LOCAL CONFINEMENT; MEAN SQUARE DISPLACEMENT; METABOLIC LABELING; PALMITOYLATION; RANDOM WALK; SINGLE PARTICLE TRACKING; WILD TYPES;

DIFFUSION; MASS SPECTROMETRY;

ACYLATION;

ADENOSINE A2 R309C RECEPTOR; ADENOSINE A2 RECEPTOR; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; MUTANT PROTEIN; QUANTUM DOT; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BIOENGINEERING; CARBOXY TERMINAL SEQUENCE; COLLISION COUPLING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIFFUSION; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIPID RAFT; MASS SPECTROMETRY; METABOLISM; PALMITOYLATION; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; CELL LINE; HUMANS; LIPOYLATION; MEMBRANE MICRODOMAINS; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; QUANTUM DOTS; RECEPTOR, ADENOSINE A2A;

EID: 84871341426     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.393579     Document Type: Article

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