Effect of formulation variables on dissolution of water-soluble drug from polyelectrolyte complex beads

Dissolution Technologies

Volumn 19, Issue 4, 2012, Pages 21-28

  Saleem, M A ^a,b   Kotadia, Divesh R ^a   Kulkarni, Raghavendra V ^c  

^a Luqman College of Pharmacy   (India)

^b ACHARYA NAGARJUNA UNIVERSITY   (India)

^c BLDE University Campus   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; ALUMINUM CHLORIDE; BUFFER; CALCIUM CHLORIDE; CARBOXYMETHYLCELLULOSE; CARRAGEENAN; CHITOSAN; POLYELECTROLYTE; POTASSIUM CHLORIDE; VERAPAMIL;

ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ENTRAPMENT EFFICIENCY; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; GELATION; INFRARED SPECTROSCOPY; PARTICLE SIZE; PH; PHYSICAL PARAMETERS; POLYELECTROLYTE COMPLEX BEAD; SCANNING ELECTRON MICROSCOPY; SWELLING BEHAVIOR;

EID: 84871336730     PISSN: 1521298X     EISSN: None     Source Type: Journal    
DOI: 10.14227/DT190412P21     Document Type: Article

References (14)

1. Bhattarai, N.; Gunn, J. J.; Zhang, M. Chitosan-based hydrogels for controlled, localized drug delivery. Adv. Drug Deliv. Rev. 2010, 62 (1), 83-99.
2. Naidu, V. G. M.; Madhusudhana, K.; Sashidhar, R. B.; Ramakrishna, S.; Khar, R. K.; Ahmed, F. J.; Diwan, P. V. Polyelectrolyte complexes of gum kondagogu and chitosan, as diclofenac carriers. Carbohydr. Polym. 2009, 76 (3), 464-471.
3. Felt, O.; Buri, P.; Gurny, R. Chitosan: A Unique Polysaccharide for Drug Delivery. Drug Dev. Ind. Pharm. 1998, 24 (11), 979-993.
4. Lankalapalli, L.; Kolapalli, V. R. M. Polyelectrolyte Complexes: A Review of their Applicability in Drug Delivery Technology. Indian J. Pharm. Sci. 2009, 71 (5), 481-487.
5. Berger, J.; Reist, M.; Mayer, J. M.; Felt, O.; Peppas, N. A.; Gurny, R. Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications. Eur. J. Pharm. Biopharm. 2004, 57 (1), 19-34.
6. Long, D. D.; VanLuyen, D. Chitosan-Carboxymethylcellulose Hydrogels as Supports for Cell Immobilization. J. Macromol. Sci. A 1996, 33 (12), 1875-1884.
7. Wang, H.; Li, W.; Lu, Y.; Wang, Z. Studies on chitosan and poly(acrylic acid) Interpolymer Complex I. Preparation, structure, pH-sensitivity, and salt sensitivity of complex-forming poly(acrylic acid): Chitosan semi-interpenetrating polymer network. J. Appl. Polym. Sci. 1997, 65 (8), 1445-1450.
8. Takahashi, T.; Takayama, K.; Machida, Y.; Nagai, T. Characteristics of Polyion Complexes of Chitosan with Sodium Alginate and Sodium Polyacrylate. Int. J. Pharm. 1990, 61 (1-2), 35-41.
9. Lee, J. W.; Kim, S. Y.; Kim, S. S.; Lee, Y. M.; Lee, K. H.; Kim, S. J. Synthesis and Characteristics of Interpenetrating Polymer Network Hydrogel Composed of Chitosan and Poly(acrylic acid). J. Appl. Polym. Sci. 1999, 73 (1), 113-120.
10. Hamman, J. H. Chitosan Based Polyelectrolyte Complexes as Potential Carrier Materials in Drug Delivery Systems. Mar. Drugs 2010, 8 (4), 1305-1322.
11. Patel, A.; Moin, M.; Shah, D.; Patel, V. Development and In Vivo Floating Behavior of Verapamil HCl Intragastric Floating Tablets. AAPS PharmSciTech 2009, 10 (1), 310-315.
12. Kunte, S.; Tandale, P. Fast dissolving strips: A novel approach for the delivery of verapamil. J. Pharm. Bioallied Sci. 2010, 2 (4), 325-328.
13. Chandira, M.; Debjit, M.; Chiranjib, K.; Jayakar, B. Formulation, design and development of buccoadheshive tablets of verapamil hydrochloride. Int. J. PharmTech Res. 2009, 1 (4), 1663-1677.
14. Daly, M. M.; Knorr, D. Chitosan-Alginate Complex Coacervate Capsules: Effects of Calcium Chloride, Plasticizers, and Polyelectrolytes on Mechanical Stability. Biotechnol. Prog. 1988, 4 (2), 76-81.