Overcoming hypoxia in 3D culture systems for tissue engineering of bone in vitro using an automated, oxygen-triggered feedback loop

Journal of Materials Science: Materials in Medicine

Volumn 23, Issue 11, 2012, Pages 2793-2801

  Volkmer, Elias ^a   Otto, Sven ^a,b   Polzer, Hans ^a   Saller, Maximilian ^a,c   Trappendreher, Daniel ^a   Zagar, Darin ^a,b   Hamisch, Sabine ^a,d   Ziegler, Günter ^a,d,e   Wilhelmi, Arndt ^a,f   Mutschler, Wolf ^a   Schieker, Matthias ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF APPLIED SCIENCES   (Germany)

^d BioCer Entwicklungs GmbH   (Germany)

^e UNIVERSITY OF BAYREUTH   (Germany)

^f Tutogen Medical ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3-D CULTURE SYSTEM; BONE TISSUE ENGINEERING; BONY DEFECTS; CULTURE CONDITIONS; FEED-BACK LOOP; IN-VITRO; INDUCTIVE FEEDBACK; INHOMOGENEOUS TISSUES; INNER SURFACES; OXYGEN CONCENTRATIONS; PERFUSION BIOREACTOR; PREOSTEOBLASTIC CELLS; PUMP SPEED; STATIC CONDITIONS; THREE-DIMENSIONAL CULTURE SYSTEM;

BIOREACTORS; BONE; CELL CULTURE; CELLS; OXYGEN SUPPLY; THREE DIMENSIONAL; TISSUE;

SCAFFOLDS (BIOLOGY);

OXYGEN; TISSUE SCAFFOLD;

ANIMAL CELL; ARTICLE; AUTOMATION; BIOREACTOR; CELL CULTURE; CONTROLLED STUDY; CULTURE TECHNIQUE; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; HYPOXIA; MOUSE; NONHUMAN; OSTEOBLAST; OXYGEN CONCENTRATION; PRIORITY JOURNAL; THREE DIMENSIONAL CULTURE SYSTEM; TISSUE ENGINEERING;

3T3 CELLS; ANIMALS; AUTOMATION; BIOREACTORS; BONE AND BONES; CELL CULTURE TECHNIQUES; CELL HYPOXIA; HYDROGEN-ION CONCENTRATION; MICE; OXYGEN; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84871333002     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-012-4725-0     Document Type: Article

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