Inflammation and Immune-Related Candidate Gene Associations with Acute Lung Injury Susceptibility and Severity: A Validation Study

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  O'Mahony, D Shane ^a   Glavan, Bradford J ^a   Holden, Tarah D ^a   Fong, Christie ^a   Black, R Anthony ^c   Rona, Gail ^a   Tejera, Paula ^b   Christiani, David C ^b   Wurfel, Mark M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; MANNOSE BINDING LECTIN 2; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN A;

ACUTE LUNG INJURY; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGED; ARTICLE; ARTIFICIAL VENTILATION; CAUCASIAN; CONTROLLED STUDY; CRITICAL ILLNESS; DISEASE SEVERITY; FEMALE; GENE FREQUENCY; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; IL6 GENE; IL8 GENE; IMMUNE RESPONSE GENE; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MALE; MBL2 GENE; MORTALITY; NAMPT GENE; NFE2L2 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TREATMENT DURATION; VALIDATION STUDY;

ACUTE LUNG INJURY; AGED; COHORT STUDIES; FEMALE; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RESPIRATION, ARTIFICIAL; SEVERITY OF ILLNESS INDEX;

EID: 84871323433     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051104     Document Type: Article

References (39)

1. Luhr OR, Antonsen K, Karlsson M, Aardal S, Thorsteinsson A, et al. (1999) Incidence and mortality after acute respiratory failure and acute respiratory distress syndrome in Sweden, Denmark, and Iceland. The ARF Study Group. Am J Respir Crit Care Med 159: 1849-1861.
2. Roupie E, Lepage E, Wysocki M, Fagon JY, Chastre J, et al. (1999) Prevalence, etiologies and outcome of the acute respiratory distress syndrome among hypoxemic ventilated patients. SRLF Collaborative Group on Mechanical Ventilation. Société de Réanimation de Langue Française. Intensive Care Med 25: 920-929.
3. Goss CH, Brower RG, Hudson LD, Rubenfeld GD, (2003) Incidence of acute lung injury in the United States. Crit Care Med 31: 1607-1611 doi:10.1097/01.CCM.0000063475.65751.1D.
4. Bersten AD, Edibam C, Hunt T, Moran J, (2002) Incidence and mortality of acute lung injury and the acute respiratory distress syndrome in three Australian States. Am J Respir Crit Care Med 165: 443-448.
5. Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, et al. (2005) Incidence and outcomes of acute lung injury. N Engl J Med 353: 1685-1693 doi:10.1056/NEJMoa050333.
6. Gao L, Barnes KC, (2009) Recent advances in genetic predisposition to clinical acute lung injury. American Journal of Physiology- Lung Cellular and Molecular Physiology 296: L713-L725 doi:10.1152/ajplung.90269.2008.
7. Christie JD, Ma S-F, Aplenc R, Li M, Lanken PN, et al. (2008) Variation in the MYLK gene is associated with development of acute lung injury after major trauma. Crit Care Med Available: http://www.ncbi.nlm.nih.gov/pubmed/18766098. Accessed 6 June 2011.
8. Marzec JM, Christie JD, Reddy SP, Jedlicka AE, Vuong H, et al. (2007) Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury. FASEB J 21: 2237-2246 doi:10.1096/fj.06-7759com.
9. Bajwa EK, Yu C-L, Gong MN, Thompson BT, Christiani DC, (2007) Pre-B-cell colony-enhancing factor gene polymorphisms and risk of acute respiratory distress syndrome. Crit Care Med 35: 1290-1295 doi:10.1097/01.CCM.0000260243.22758.4F.
10. Christie JD, (2006) Interleukin-10, age and acute lung injury genetics: the action is in the interaction. Eur Respir J 27: 669-670 doi:10.1183/09031936.06.00017306.
11. Flores C, Ma S-F, Maresso K, Wade MS, Villar J, et al. (2008) IL6 gene-wide haplotype is associated with susceptibility to acute lung injury. Transl Res 152: 11-17 doi:10.1016/j.trsl.2008.05.006.
12. The International HapMap Project (2003) Nature 426: 789-796 doi:10.1038/nature02168.
13. Glavan BJ, Holden TD, Goss CH, Black RA, Neff MJ, et al. (2011) Genetic variation in the FAS gene and associations with acute lung injury. Am J Respir Crit Care Med 183: 356-363 doi:10.1164/rccm.201003-0351OC.
14. Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, et al. (2012) Acute respiratory distress syndrome: the Berlin Definition. JAMA 307: 2526-2533 doi:10.1001/jama.2012.5669.
15. Stapleton RD, Martin TR, Weiss NS, Crowley JJ, Gundel SJ, et al. (2011) A phase II randomized placebo-controlled trial of omega-3 fatty acids for the treatment of acute lung injury. Crit Care Med 39: 1655-1662 doi:10.1097/CCM.0b013e318218669d.
16. Wiedemann HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, et al. (2006) Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 354: 2564-2575 doi:10.1056/NEJMoa062200.
17. Marshall RP, Webb S, Hill MR, Humphries SE, Laurent GJ, (2002) Genetic polymorphisms associated with susceptibility and outcome in ARDS. Chest 121: 68S-69S.
18. Shah CV, Lanken PN, Localio AR, Gallop R, Bellamy S, et al. (2010) An alternative method of acute lung injury classification for use in observational studies. Chest 138: 1054-1061 doi:10.1378/chest.09-2697.
19. Ye SQ, Simon BA, Maloney JP, Zambelli-Weiner A, Gao L, et al. (2005) Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. Am J Respir Crit Care Med 171: 361-370 doi:10.1164/rccm.200404-563OC.
20. Hildebrand F, Stuhrmann M, van Griensven M, Meier S, Hasenkamp S, et al. (2007) Association of IL-8-251A/T polymorphism with incidence of Acute Respiratory Distress Syndrome (ARDS) and IL-8 synthesis after multiple trauma. Cytokine 37: 192-199 doi:10.1016/j.cyto.2007.03.008.
21. Gong MN, Zhou W, Williams PL, Thompson BT, Pothier L, et al. (2005) -308GA and TNFB polymorphisms in acute respiratory distress syndrome. Eur Respir J 26: 382-389 doi:10.1183/09031936.05.00000505.
22. Bouros D, Alexandrakis MG, Antoniou KM, Agouridakis P, Pneumatikos I, et al. (2004) The clinical significance of serum and bronchoalveolar lavage inflammatory cytokines in patients at risk for Acute Respiratory Distress Syndrome. BMC Pulm Med 4: 6 doi:10.1186/1471-2466-4-6.
23. Meduri GU, Headley S, Kohler G, Stentz F, Tolley E, et al. (1995) Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1 beta and IL-6 levels are consistent and efficient predictors of outcome over time. Chest 107: 1062-1073.
24. Parsons PE, Eisner MD, Thompson BT, Matthay MA, Ancukiewicz M, et al. (2005) Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med 33: 1-6 discussion 230-232.
25. Fishman D, Faulds G, Jeffery R, Mohamed-Ali V, Yudkin JS, et al. (1998) The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 102: 1369-1376 doi:10.1172/JCI2629.
26. Wang N, Zhou R, Wang C, Guo X, Chen Z, et al. (2012) -251 T/A polymorphism of the interleukin-8 gene and cancer risk: a HuGE review and meta-analysis based on 42 case-control studies. Mol Biol Rep 39: 2831-2841 doi:10.1007/s11033-011-1042-5.
27. Ahn M-H, Park B-L, Lee S-H, Park S-W, Park J-S, et al. (2011) A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode. Respir Res 12: 73 doi:10.1186/1465-9921-12-73.
28. Andia DC, Letra A, Casarin RCV, Casati MZ, Line SRP, et al. (2012) Genetic analysis of the IL8 gene polymorphism (rs4073) in generalized aggressive periodontitis. Archives of oral biology. Available: http://www.ncbi.nlm.nih.gov/pubmed/22727395. Accessed 10 July 2012.
29. Nonas SA, Finigan JH, Gao L, Garcia JGN, (2005) Functional genomic insights into acute lung injury: role of ventilators and mechanical stress. Proc Am Thorac Soc 2: 188-194 doi:10.1513/pats.200501-005AC.
30. Sutherland AM, Walley KR, Manocha S, Russell JA, (2005) The association of interleukin 6 haplotype clades with mortality in critically ill adults. Arch Intern Med 165: 75-82 doi:10.1001/archinte.165.1.75.
31. Cho H-Y, Jedlicka AE, Reddy SPM, Zhang L-Y, Kensler TW, et al. (2002) Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene. Am J Respir Cell Mol Biol 26: 42-51.
32. Edwards BJ, Haynes C, Levenstien MA, Finch SJ, Gordon D, (2005) Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies. BMC Genet 6: 18 doi:10.1186/1471-2156-6-18.
33. Su L, Zhai R, Sheu C-C, Gallagher DC, Gong MN, et al. (2009) Genetic variants in the angiopoietin-2 gene are associated with increased risk of ARDS. Intensive Care Med 35: 1024-1030 doi:10.1007/s00134-009-1413-8.
34. Sheu CC, Zhai R, Su L, Tejera P, Gong MN, et al. (2009) Sex-specific association of epidermal growth factor gene polymorphisms with acute respiratory distress syndrome. Eur Respir J 33: 543-550 doi:10.1183/09031936.00091308.
35. Gong MN, Thompson BT, Williams PL, Zhou W, Wang MZ, et al. (2006) Interleukin-10 polymorphism in position -1082 and acute respiratory distress syndrome. Eur Respir J 27: 674-681 doi:10.1183/09031936.06.00046405.
36. Gong MN, Zhou W, Williams PL, Thompson BT, Pothier L, et al. (2007) Polymorphisms in the mannose binding lectin-2 gene and acute respiratory distress syndrome. Crit Care Med 35: 48-56 doi:10.1097/01.CCM.0000251132.10689.F3.
37. Quasney MW, Waterer GW, Dahmer MK, Kron GK, Zhang Q, et al. (2004) Association between surfactant protein B+1580 polymorphism and the risk of respiratory failure in adults with community-acquired pneumonia. Crit Care Med 32: 1115-1119.
38. Medford ARL, Keen LJ, Bidwell JL, Millar AB, (2005) Vascular endothelial growth factor gene polymorphism and acute respiratory distress syndrome. Thorax 60: 244-248 doi:10.1136/thx.2004.034785.
39. Skol AD, Scott LJ, Abecasis GR, Boehnke M, (2006) Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet 38: 209-213 doi:10.1038/ng1706.