Adaptive immunity and atherosclerosis: Mouse tales in the AJP

American Journal of Pathology

Volumn 182, Issue 1, 2013, Pages 5-9

  Lichtman, Andrew H ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 5; T LYMPHOCYTE RECEPTOR;

ADAPTIVE IMMUNITY; ARTICLE; ATHEROSCLEROSIS; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHOLESTEROL BLOOD LEVEL; CYTOKINE PRODUCTION; HYPERCHOLESTEROLEMIA; IMMUNE DEFICIENCY; NONHUMAN; PRIORITY JOURNAL; TH2 CELL; TRANSGENIC ANIMAL;

EID: 84871321148     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.10.006     Document Type: Review

References (42)

1. B.D. Lamon, and D.P. Hajjar Inflammation at the molecular interface of atherogenesis: an anthropological journey Am J Pathol 173 2008 1253 1264
2. L. Jonasson, J. Holm, O. Skalli, G. Bondjers, and G.K. Hansson Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque Arteriosclerosis 6 1986 131 138 (Pubitemid 16024121)
3. G.K. Hansson, L. Jonasson, B. Lojsthed, S. Stemme, O. Kocher, and G. Gabbiani Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques Atherosclerosis 72 1988 135 141
4. E.E. Emeson, and A.L. Robertson Jr. T lymphocytes in aortic and coronary intimas. Their potential role in atherogenesis Am J Pathol 130 1988 369 376 (Pubitemid 18076371)
5. B. Paigen, A. Morrow, C. Brandon, D. Mitchell, and P. Holmes Variation in susceptibility to atherosclerosis among inbred strains of mice Atherosclerosis 57 1985 65 73 (Pubitemid 15247039)
6. E.E. Emeson, and M.L. Shen Accelerated atherosclerosis in hyperlipidemic C57BL/6 mice treated with cyclosporin A Am J Pathol 142 1993 1906 1915 (Pubitemid 24057085)
7. E.E. Emeson, M.L. Shen, C.G. Bell, and A. Qureshi Inhibition of atherosclerosis in CD4 T-cell-ablated and nude (nu/nu) C57BL/6 hyperlipidemic mice Am J Pathol 149 1996 675 685 (Pubitemid 26256354)
8. X. Zhou, S. Stemme, and G.K. Hansson Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E- deficient mice Am J Pathol 149 1996 359 366 (Pubitemid 26256325)
9. R. Elhage, P. Gourdy, L. Brouchet, J. Jawien, M.J. Fouque, C. Fievet, X. Huc, Y. Barreira, J.C. Couloumiers, J.F. Arnal, and F. Bayard Deleting TCR alpha beta+ or CD4+ T lymphocytes leads to opposite effects on site-specific atherosclerosis in female apolipoprotein E-deficient mice Am J Pathol 165 2004 2013 2018 (Pubitemid 39578379)
10. A.S. Plump, J.D. Smith, T. Hayek, K. Aalto-Setälä, A. Walsh, J.G. Verstuyft, E.M. Rubin, and J.L. Breslow Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells Cell 71 1992 343 353
11. S.H. Zhang, R.L. Reddick, J.A. Piedrahita, and N. Maeda Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E Science 258 1992 468 471
12. S. Ishibashi, M.S. Brown, J.L. Goldstein, R.D. Gerard, R.E. Hammer, and J. Herz Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery J Clin Invest 92 1993 883 893 (Pubitemid 23262411)
13. S. Ishibashi, J. Herz, N. Maeda, J.L. Goldstein, and M.S. Brown The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins Proc Natl Acad Sci USA 91 1994 4431 4435
14. S.E. Roselaar, P.X. Kakkanathu, and A. Daugherty Lymphocyte populations in atherosclerotic lesions of ApoE -/- and LDL receptor -/- mice. Decreasing density with disease progression Arterioscler Thromb Vasc Biol 16 1996 1013 1018 (Pubitemid 26266901)
15. A.H. Lichtman, M. Cybulsky, and F.W. Luscinskas Immunology of atherosclerosis: The promise of mouse models Am J Pathol 149 1996 351 357
16. P.S. Russell, C.M. Chase, and R.B. Colvin Accelerated atheromatous lesions in mouse hearts transplanted to apolipoprotein-E-deficient recipients Am J Pathol 149 1996 91 99 (Pubitemid 26230982)
17. H.M. Dansky, S.A. Charlton, M.M. Harper, and J.D. Smith T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouse Proc Natl Acad Sci USA 94 1997 4642 4646 (Pubitemid 27194296)
18. A. Daugherty, E. Puré, D. Delfel-Butteiger, S. Chen, J. Leferovich, S.E. Roselaar, and D.J. Rader The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- mice J Clin Invest 100 1997 1575 1580 (Pubitemid 27425785)
19. X. Zhou, A. Nicoletti, R. Elhage, and G.K. Hansson Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice Circulation 102 2000 2919 2922
20. L. Song, C. Leung, and C. Schindler Lymphocytes are important in early atherosclerosis J Clin Invest 108 2001 251 259 (Pubitemid 32656249)
21. C.J. Binder, M.Y. Chou, L. Fogelstrand, K. Hartvigsen, P.X. Shaw, A. Boullier, and J.L. Witztum Natural antibodies in murine atherosclerosis Curr Drug Targets 9 2008 190 195 (Pubitemid 351843599)
22. G.K. Hansson, A.K. Robertson, and C. Söderberg-Nauclér Inflammation and atherosclerosis Annu Rev Pathol 1 2006 297 329
23. J. Nilsson, M. Wigren, and P.K. Shah Regulatory T cells and the control of modified lipoprotein autoimmunity-driven atherosclerosis Trends Cardiovasc Med 19 2009 272 276
24. R. Elhage, P. Gourdy, J. Jawien, L. Brouchet, C. Castano, C. Fievet, G.K. Hansson, J.F. Arnal, and F. Bayard The atheroprotective effect of 17beta-estradiol depends on complex interactions in adaptive immunity Am J Pathol 167 2005 267 274 (Pubitemid 40884787)
25. T.R. Mosmann, H. Cherwinski, M.W. Bond, M.A. Giedlin, and R.L. Coffman Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins J Immunol 136 1986 2348 2357 (Pubitemid 16136806)
26. A. Peters, Y. Lee, and V.K. Kuchroo The many faces of Th17 cells Curr Opin Immunol 23 2011 702 706
27. S.Z. Josefowicz, L.F. Lu, and A.Y. Rudensky Regulatory T cells: mechanisms of differentiation and function Annu Rev Immunol 30 2012 531 564
28. R. Elhage, J. Jawien, M. Rudling, H.G. Ljunggren, K. Takeda, S. Akira, F. Bayard, and G.K. Hansson Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice Cardiovasc Res 59 2003 234 240 (Pubitemid 36776389)
29. S. Gupta, A.M. Pablo, X. Jiang, N. Wang, A.R. Tall, and C. Schindler IFN-gamma potentiates atherosclerosis in ApoE knock-out mice J Clin Invest 99 1997 2752 2761 (Pubitemid 27259823)
30. C. Buono, C.E. Come, G. Stavrakis, G.F. Maguire, P.W. Connelly, and A.H. Lichtman Influence of interferon-gamma on the extent and phenotype of diet-induced atherosclerosis in the LDLR-deficient mouse Arterioscler Thromb Vasc Biol 23 2003 454 460 (Pubitemid 36337222)
31. C. Buono, C.J. Binder, G. Stavrakis, J.L. Witztum, L.H. Glimcher, and A.H. Lichtman T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses Proc Natl Acad Sci USA 102 2005 1596 1601 (Pubitemid 40209213)
32. J. Frostegård, A.K. Ulfgren, P. Nyberg, U. Hedin, J. Swedenborg, U. Andersson, and G.K. Hansson Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines Atherosclerosis 145 1999 33 43 (Pubitemid 29292698)
33. G.K. Hansson, J. Holm, and L. Jonasson Detection of activated T lymphocytes in the human atherosclerotic plaque Am J Pathol 135 1989 169 175 (Pubitemid 19229001)
34. S.C. Whitman, P. Ravisankar, H. Elam, and A. Daugherty Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-/- mice Am J Pathol 157 2000 1819 1824
35. P. Davenport, and P.G. Tipping The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice Am J Pathol 163 2003 1117 1125 (Pubitemid 37040147)
36. S. Schulte, G.K. Sukhova, and P. Libby Genetically programmed biases in Th1 and Th2 immune responses modulate atherogenesis Am J Pathol 172 2008 1500 1508 (Pubitemid 351793344)
37. Z. Mallat, S. Besnard, M. Duriez, V. Deleuze, F. Emmanuel, M.F. Bureau, F. Soubrier, B. Esposito, H. Duez, C. Fievet, B. Staels, N. Duverger, D. Scherman, and A. Tedgui Protective role of interleukin-10 in atherosclerosis Circ Res 85 1999 e17 e24
38. S. Potteaux, B. Esposito, O. van Oostrom, V. Brun, P. Ardouin, H. Groux, A. Tedgui, and Z. Mallat Leukocyte-derived interleukin 10 is required for protection against atherosclerosis in low-density lipoprotein receptor knockout mice Arterioscler Thromb Vasc Biol 24 2004 1474 1478 (Pubitemid 39050443)
39. A.K. Robertson, M. Rudling, X. Zhou, L. Gorelik, R.A. Flavell, and G.K. Hansson Disruption of TGF-beta signaling in T cells accelerates atherosclerosis J Clin Invest 112 2003 1342 1350 (Pubitemid 38057688)
40. O. Ovchinnikova, A.K. Robertson, D. Wågsäter, E.J. Folco, M. Hyry, J. Myllyharju, P. Eriksson, P. Libby, and G.K. Hansson T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice Am J Pathol 174 2009 693 700
41. Y. Furukawa, D.A. Mandelbrot, P. Libby, A.H. Sharpe, and R.N. Mitchell Association of B7-1 co-stimulation with the development of graft arterial disease. Studies using mice lacking B7-1, B7-2, or B7-1/B7-2 Am J Pathol 157 2000 473 484 (Pubitemid 30626910)
42. A.H. Lichtman T cell costimulatory and coinhibitory pathways in vascular inflammatory diseases Fronteirs Physiol 3 2012 1 18