Combining structure and function to evaluate glaucomatous progression: Implications for the design of clinical trials

Current Opinion in Pharmacology

Volumn 13, Issue 1, 2013, Pages 115-122

  Lisboa, Renato ^a,b   Weinreb, Robert N ^a   Medeiros, Felipe A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL TRIAL (TOPIC); CONFOCAL LASER MICROSCOPY; CONFOCAL SCANNING LASER OPHTHALMOSCOPY; CONFOCAL SCANNING LASER POLARIMETRY; DISEASE COURSE; GLAUCOMA; HUMAN; INTRAOCULAR PRESSURE; OPTIC DISK; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RETINA GANGLION CELL; RETINA NERVE CELL; RISK FACTOR; VISUAL FIELD; VISUAL FIELD DEFECT;

EID: 84871320765     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2012.10.010     Document Type: Review

References (27)

1. M.A. Kass, D.K. Heuer, E.J. Higginbotham, C.A. Johnson, J.L. Keltner, J.P. Miller, R.K. Parrish, M.R. Wilson, and M.O. Gordon The ocular hypertension treatment study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma Arch. Ophthalmol. 120 2002 701 713 discussion 829-30
2. S.M. Drance The collaborative normal-tension glaucoma study and some of its lessons Can. J. Ophthalmol. 34 1999 1 6
3. S. Miglior, T. Zeyen, N. Pfeiffer, J. Cunha-Vaz, V. Torri, and I. Adamsons Results of the European glaucoma prevention study Ophthalmology 112 2005 366 375
4. J. Katz, N. Congdon, and D.S. Friedman Methodological variations in estimating apparent progressive visual field loss in clinical trials of glaucoma treatment Arch. Ophthalmol. 117 1999 1137 1142
5. C.K. Leung, C.Y.L. Cheung, R.N. Weinreb, K. Qiu, S. Liu, H. Li, G. Xu, N. Fan, C.P. Pang, K.K. Tse, and D.S.C. Lam Evaluation of retinal nerve fiber layer progression in glaucoma: a study on optical coherence tomography guided progression analysis Invest. Ophthalmol. Vis. Sci. 51 2010 217 222
6. F.A. Medeiros, L.M. Alencar, L.M. Zangwill, C. Bowd, P.A. Sample, and R.N. Weinreb Prediction of functional loss in glaucoma from progressive optic disc damage Arch. Ophthalmol. 127 2009 1250 1256
7. N.G. Strouthidis, A. Scott, N.M. Peter, and D.F. Garway-Heath Optic disc and visual field progression in ocular hypertensive subjects: detection rates, specificity, and agreement Invest. Ophthalmol. Vis. Sci. 47 2006 2904 2910
8. F.A. Medeiros, L.M. Zangwill, L.M. Alencar, C. Bowd, P.A. Sample, R. Susanna Jr., and R.N. Weinreb Detection of glaucoma progression with stratus OCT retinal nerve fiber layer, optic nerve head, and macular thickness measurements Invest. Ophthalmol. Vis. Sci. 50 2009 5741 5748
9. F.A. Medeiros, L.M. Zangwill, L.M. Alencar, P.A. Sample, and R.N. Weinreb Rates of progressive retinal nerve fiber layer loss in glaucoma measured by scanning laser polarimetry Am. J. Ophthalmol. 149 2010 908 915
10. F.A. Medeiros, L.M. Zangwill, C. Bowd, P.A. Sample, and R.N. Weinreb Use of progressive glaucomatous optic disk change as the reference standard for evaluation of diagnostic tests in glaucoma Am. J. Ophthalmol. 139 2005 1010 1018
11. C.K. Leung, V. Chiu, R.N. Weinreb, S. Liu, C. Ye, G. Lai, N. Liu, C.P. Pang, K.K. Tse, and D.S.C. Lam Evaluation of retinal nerve fiber layer progression in glaucoma: a comparison between spectral-domain and time-domain optical coherence tomography Ophthalmology 118 2011 1558 1562
12. G. Wollstein, J.S. Schuman, L.L. Price, A. Aydin, P.C. Stark, E. Hertzmark, E. Lai, H. Ishikawa, C. Mattox, and J.G. Fujimoto Optical coherence tomography longitudinal evaluation of retinal nerve fiber layer thickness in glaucoma Arch. Ophthalmol. 123 2005 464 470
13. F.A. Medeiros, L.M. Zangwill, C. Bowd, K. Mansouri, and R.N. Weinreb The structure and function relationship in glaucoma: implications for detection of progression and measurement of rates of change Invest. Ophthalmol. Vis. Sci. 53 2012 6939 6946
14. R.S. Harwerth, J.L. Wheat, M.J. Fredette, and D.R. Anderson Linking structure and function in glaucoma Prog. Retin. Eye Res. 29 2010 249 271
15. D.C. Hood, and R.H. Kardon A framework for comparing structural and functional measures of glaucomatous damage Prog. Retin. Eye Res. 26 2007 688 710
16. F.A. Medeiros, R. Lisboa, R.N. Weinreb, C.A. Girkin, J.M. Liebmann, and L.M. Zangwill A combined index of structure and function for staging glaucomatous damage Arch. Ophthalmol. 130 2012 E1 E10
17. R.S. Harwerth, L. Carter-Dawson, E.L. Smith 3rd, G. Barnes, W.F. Holt, and M.L. Crawford Neural losses correlated with visual losses in clinical perimetry Invest. Ophthalmol. Vis. Sci. 45 2004 3152 3160
18. F.A. Medeiros, L.M. Alencar, L.M. Zangwill, P.A. Sample, and R.N. Weinreb The relationship between intraocular pressure and progressive retinal nerve fiber layer loss in glaucoma Ophthalmology 116 2009 1125 1133 e1-3
19. D.F. Garway-Heath, J. Caprioli, F.W. Fitzke, and R.A. Hitchings Scaling the hill of vision: the physiological relationship between light sensitivity and ganglion cell numbers Invest. Ophthalmol. Vis. Sci. 41 2000 1774 1782
20. W.H. Swanson, J. Felius, and F. Pan Perimetric defects and ganglion cell damage: interpreting linear relations using a two-stage neural model Invest. Ophthalmol. Vis. Sci. 45 2004 466 472
21. R.N. Weinreb, and P.T. Khaw Primary open-angle glaucoma Lancet 363 2004 1711 1720
22. D.R. Anderson, S.M. Drance, and M. Schulzer Natural history of normal-tension glaucoma Ophthalmology 108 2001 247 253
23. A. Heijl, B. Bengtsson, L. Hyman, and M.C. Leske Natural history of open-angle glaucoma Ophthalmology 116 2009 2271 2276
24. F.A. Medeiros, L.M. Zangwill, D.R. Anderson, J.M. Liebmann, C.A. Girkin, R.S. Harwerth, M.J. Fredette, and R.N. Weinreb Estimating the rate of retinal ganglion cell loss in glaucoma Am. J. Ophthalmol. 154 2012 814 824
25. F.A. Medeiros, M.T. Leite, L.M. Zangwill, and R.N. Weinreb Combining structural and functional measurements to improve detection of glaucoma progression using Bayesian hierarchical models Invest. Ophthalmol. Vis. Sci. 52 2011 5794 5803
26. R.A. Russell, R. Malik, B.C. Chauhan, D.P. Crabb, and D.F. Garway-Heath Improved estimates of visual field progression using Bayesian linear regression to integrate structural information in patients with ocular hypertension Invest. Ophthalmol. Vis. Sci. 53 2012 2760 2769
27. F.A. Medeiros, L.M. Zangwill, K. Mansouri, R. Lisboa, A. Tafreshi, and R.N. Weinreb Incorporating risk factors to improve the assessment of rates of glaucomatous progression Invest. Ophthalmol. Vis. Sci. 53 2012 2199 2207