메뉴 건너뛰기




Volumn 7, Issue 12, 2012, Pages 1863-1876

Effect of high-pressure homogenization and stabilizers on the physicochemical properties of curcumin-loaded glycerol monooleate/chitosan nanostructures

Author keywords

Caco 2 cells; chitosan; curcumin; glyceryl monooleate; high pressure homogenization; poloxamer 407; polyvinyl alcohol

Indexed keywords

CHITOSAN; CURCUMIN; GLYCEROL OLEATE; NANOMATERIAL; POLOXAMER; POLYVINYL ALCOHOL; STABILIZING AGENT;

EID: 84871306094     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.12.49     Document Type: Article
Times cited : (27)

References (49)
  • 1
    • 55949084512 scopus 로고    scopus 로고
    • Biological activities of curcumin and its analogues (congeners) made by man and Mother Nature
    • Anand P, Thomas SG, Kunnumakkara AB et al. Biological activities of curcumin and its analogues (congeners) made by man and Mother Nature. Biochem. Pharmacol. 76(11), 1590-1611 (2008).
    • (2008) Biochem. Pharmacol. , vol.76 , Issue.11 , pp. 1590-1611
    • Anand, P.1    Thomas, S.G.2    Kunnumakkara, A.B.3
  • 2
    • 16844371915 scopus 로고    scopus 로고
    • Induction of apoptosis by curcumin and its implications for cancer therapy
    • Karunagaran D, Rashmi R, Kumar TR. Induction of apoptosis by curcumin and its implications for cancer therapy. Curr. Cancer Drug Targets 5(2), 117-129 (2005).
    • (2005) Curr. Cancer Drug Targets , vol.5 , Issue.2 , pp. 117-129
    • Karunagaran, D.1    Rashmi, R.2    Kumar, T.R.3
  • 3
    • 55949095821 scopus 로고    scopus 로고
    • Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells
    • Reuter S, Eifes S, Dicato M, Aggarwal BB, Diederich M. Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells. Biochem. Pharmacol. 76(11), 1340-1351 (2008).
    • (2008) Biochem. Pharmacol. , vol.76 , Issue.11 , pp. 1340-1351
    • Reuter, S.1    Eifes, S.2    Dicato, M.3    Aggarwal, B.B.4    Diederich, M.5
  • 4
    • 0036160713 scopus 로고    scopus 로고
    • Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine
    • Ireson CR, Jones DJ, Orr S et al. Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine. Cancer Epidemiol. Biomarkers Prev. 11(1), 105-111 (2002).
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , Issue.1 , pp. 105-111
    • Ireson, C.R.1    Jones, D.J.2    Orr, S.3
  • 5
    • 37549051274 scopus 로고    scopus 로고
    • Bioavailability of curcumin: Problems and promises
    • Anand P, Kunnumakkara AB, Newman RA et al. Bioavailability of curcumin: problems and promises. Mol. Pharm. 4(6), 807-818 (2007).
    • (2007) Mol. Pharm. , vol.4 , Issue.6 , pp. 807-818
    • Anand, P.1    Kunnumakkara, A.B.2    Newman, R.A.3
  • 6
    • 0040753927 scopus 로고    scopus 로고
    • Decomposition of turmeric curcuminoids as affected by light, solvent and oxygen
    • Price LC, Vuescher RW. Decomposition of turmeric curcuminoids as affected by light, solvent and oxygen. J. Food Biochem. 20(5), 125-133 (1996).
    • (1996) J. Food Biochem. , vol.20 , Issue.5 , pp. 125-133
    • Price, L.C.1    Vuescher, R.W.2
  • 7
    • 0030839940 scopus 로고    scopus 로고
    • Stability of curcumin in buffer solutions and characterization of its degradation products
    • Wang YJ, Pan MH, Cheng AL et al. Stability of curcumin in buffer solutions and characterization of its degradation products. J. Pharm. Biomed. Anal. 15(12), 1867-1876 (1997).
    • (1997) J. Pharm. Biomed. Anal. , vol.15 , Issue.12 , pp. 1867-1876
    • Wang, Y.J.1    Pan, M.H.2    Cheng, A.L.3
  • 8
    • 34248205135 scopus 로고    scopus 로고
    • Polymeric nanoparticle-encapsulated curcumin ('nanocurcumin'): A novel strategy for human cancer therapy
    • Bisht S, Feldmann G, Soni S et al. Polymeric nanoparticle-encapsulated curcumin ('nanocurcumin'): a novel strategy for human cancer therapy. J. Nanobiotechnol. 5, 3 (2007).
    • (2007) J. Nanobiotechnol. , vol.5 , pp. 3
    • Bisht, S.1    Feldmann, G.2    Soni, S.3
  • 9
    • 77957678756 scopus 로고    scopus 로고
    • Synthesis and in vitro/in vivo anti-cancer evaluation of curcumin-loaded chitosan/poly(butyl cyanoacrylate) nanoparticles
    • Duan J, Zhang Y, Han S et al. Synthesis and in vitro/in vivo anti-cancer evaluation of curcumin-loaded chitosan/poly(butyl cyanoacrylate) nanoparticles. Int. J. Pharm. 400(1-2), 211-220 (2010).
    • (2010) Int. J. Pharm. , vol.400 , Issue.1-2 , pp. 211-220
    • Duan, J.1    Zhang, Y.2    Han, S.3
  • 10
    • 24644508916 scopus 로고    scopus 로고
    • Liposome-encapsulated curcumin: In vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis
    • Li L, Braiteh FS, Kurzrock R. Liposome-encapsulated curcumin: in vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis. Cancer 104(6), 1322-1331 (2005).
    • (2005) Cancer , vol.104 , Issue.6 , pp. 1322-1331
    • Li, L.1    Braiteh, F.S.2    Kurzrock, R.3
  • 11
    • 0037026270 scopus 로고    scopus 로고
    • Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: Solubility, chemical and photochemical stability
    • Tonnesen HH, Masson M, Loftsson T. Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability. Int. J. Pharm. 244(1-2), 127-135 (2002).
    • (2002) Int. J. Pharm. , vol.244 , Issue.1-2 , pp. 127-135
    • Tonnesen, H.H.1    Masson, M.2    Loftsson, T.3
  • 12
    • 1142297630 scopus 로고    scopus 로고
    • Characterization of curcumin-PVP solid dispersion obtained by spray drying
    • Paradkar A, Ambike AA, Jadhav BK, Mahadik KR. Characterization of curcumin-PVP solid dispersion obtained by spray drying. Int. J. Pharm. 271(1-2), 281-286 (2004).
    • (2004) Int. J. Pharm. , vol.271 , Issue.1-2 , pp. 281-286
    • Paradkar, A.1    Ambike, A.A.2    Jadhav, B.K.3    Mahadik, K.R.4
  • 13
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: Production, characterization and applications
    • Mehnert W, Mader K. Solid lipid nanoparticles: production, characterization and applications. Adv. Drug Deliv. Rev. 47(2-3), 165-196 (2001).
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , Issue.2-3 , pp. 165-196
    • Mehnert, W.1    Mader, K.2
  • 14
    • 0017701219 scopus 로고
    • Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol
    • Abuchowski A, van Es T, Palczuk NC, Davis FF. Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. J. Biol. Chem. 252(11), 3578-3581 (1977).
    • (1977) J. Biol. Chem. , vol.252 , Issue.11 , pp. 3578-3581
    • Abuchowski, A.1    Van Es, T.2    Palczuk, N.C.3    Davis, F.F.4
  • 15
    • 18044366409 scopus 로고    scopus 로고
    • A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly(ethylene glycol) as carriers for oral calcitonin delivery
    • Garcia-Fuentes M, Prego C, Torres D, Alonso MJ. A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly(ethylene glycol) as carriers for oral calcitonin delivery. Eur. J. Pharm. Sci. 25(1), 133-143 (2005).
    • (2005) Eur. J. Pharm. Sci. , vol.25 , Issue.1 , pp. 133-143
    • Garcia-Fuentes, M.1    Prego, C.2    Torres, D.3    Alonso, M.J.4
  • 16
    • 79951577686 scopus 로고    scopus 로고
    • Physical stability of nanosuspensions: Investigation of the role of stabilizers on Ostwald ripening
    • Verma S, Kumar S, Gokhale R, Burgess DJ. Physical stability of nanosuspensions: investigation of the role of stabilizers on Ostwald ripening. Int. J. Pharm. 406(1-2), 145-152 (2011).
    • (2011) Int. J. Pharm. , vol.406 , Issue.1-2 , pp. 145-152
    • Verma, S.1    Kumar, S.2    Gokhale, R.3    Burgess, D.J.4
  • 17
    • 51449104994 scopus 로고    scopus 로고
    • A novel nanoparticle formulation for sustained paclitaxel delivery
    • Trickler WJ, Nagvekar AA, Dash AK. A novel nanoparticle formulation for sustained paclitaxel delivery. AAPS Pharm. Sci. Tech. 9(2), 486-493 (2008).
    • (2008) AAPS Pharm. Sci. Tech. , vol.9 , Issue.2 , pp. 486-493
    • Trickler, W.J.1    Nagvekar, A.A.2    Dash, A.K.3
  • 18
    • 67650090674 scopus 로고    scopus 로고
    • The in vitro sub-cellular localization and in vivo efficacy of novel chitosan/GMO nanostructures containing paclitaxel
    • Trickler WJ, Nagvekar AA, Dash AK. The in vitro sub-cellular localization and in vivo efficacy of novel chitosan/GMO nanostructures containing paclitaxel. Pharm. Res. 26(8), 1963-1973 (2009).
    • (2009) Pharm. Res. , vol.26 , Issue.8 , pp. 1963-1973
    • Trickler, W.J.1    Nagvekar, A.A.2    Dash, A.K.3
  • 19
    • 77950915051 scopus 로고    scopus 로고
    • Chitosan and glyceryl monooleate nanostructures containing gemcitabine: Potential delivery system for pancreatic cancer treatment
    • Trickler WJ, Khurana J, Nagvekar AA, Dash AK. Chitosan and glyceryl monooleate nanostructures containing gemcitabine: potential delivery system for pancreatic cancer treatment. AAPS Pharm. Sci. Tech. 11(1), 392-401 (2010).
    • (2010) AAPS Pharm. Sci. Tech. , vol.11 , Issue.1 , pp. 392-401
    • Trickler, W.J.1    Khurana, J.2    Nagvekar, A.A.3    Dash, A.K.4
  • 20
    • 79955596913 scopus 로고    scopus 로고
    • Antitumor efficacy, tumor distribution and blood pharmacokinetics of chitosan/glyceryl-monooleate nanostructures containing paclitaxel
    • Trickler WJ, Munt DJ, Jain N, Joshi SS, Dash AK. Antitumor efficacy, tumor distribution and blood pharmacokinetics of chitosan/glyceryl-monooleate nanostructures containing paclitaxel. Nanomedicine (Lond). 6(3), 437-448 (2011).
    • (2011) Nanomedicine (Lond). , vol.6 , Issue.3 , pp. 437-448
    • Trickler, W.J.1    Munt, D.J.2    Jain, N.3    Joshi, S.S.4    Dash, A.K.5
  • 21
    • 0031939804 scopus 로고    scopus 로고
    • Influence of surface properties at biodegradable microsphere surfaces: Effects on plasma protein adsorption and phagocytosis
    • Lacasse FX, Filion MC, Phillips NC, Escher E, McMullen JN, Hildgen P. Influence of surface properties at biodegradable microsphere surfaces: effects on plasma protein adsorption and phagocytosis. Pharm. Res. 15(2), 312-317 (1998).
    • (1998) Pharm. Res. , vol.15 , Issue.2 , pp. 312-317
    • Lacasse, F.X.1    Filion, M.C.2    Phillips, N.C.3    Escher, E.4    McMullen, J.N.5    Hildgen, P.6
  • 22
    • 84861154736 scopus 로고    scopus 로고
    • Surface modified solid lipid nanoparticulate formulation for ifosfamide: Development and characterization
    • Pandit AA, Dash AK. Surface modified solid lipid nanoparticulate formulation for ifosfamide: development and characterization. Nanomedicine (Lond.) 6(8), 1397-1412 (2011).
    • (2011) Nanomedicine (Lond.) , vol.6 , Issue.8 , pp. 1397-1412
    • Pandit, A.A.1    Dash, A.K.2
  • 23
    • 33845351355 scopus 로고    scopus 로고
    • A review of poloxamer 407 pharmaceutical and pharmacological characteristics
    • Dumortier G, Grossiord JL, Agnely F, Chaumeil JC. A review of poloxamer 407 pharmaceutical and pharmacological characteristics. Pharm. Res. 23(12), 2709-2728 (2006).
    • (2006) Pharm. Res. , vol.23 , Issue.12 , pp. 2709-2728
    • Dumortier, G.1    Grossiord, J.L.2    Agnely, F.3    Chaumeil, J.C.4
  • 24
    • 79958089505 scopus 로고    scopus 로고
    • Effect of stabilizers and process parameters for budesonide loaded PLGA-nanoparticles
    • Dinda A, Biswal I, Das D et al. Effect of stabilizers and process parameters for budesonide loaded PLGA-nanoparticles. Int. J. Drug Deliv. 3(2), 371-380 (2011).
    • (2011) Int. J. Drug Deliv. , vol.3 , Issue.2 , pp. 371-380
    • Dinda, A.1    Biswal, I.2    Das, D.3
  • 25
    • 57649174752 scopus 로고    scopus 로고
    • Effect of stabilizer on synthesis of indium tin oxide nanoparticles
    • Pan R, Qiang S, Liew K, Zhao Y, Wang R, Zhu J. Effect of stabilizer on synthesis of indium tin oxide nanoparticles. Powder Technol. 189(1), 126-129 (2009).
    • (2009) Powder Technol. , vol.189 , Issue.1 , pp. 126-129
    • Pan, R.1    Qiang, S.2    Liew, K.3    Zhao, Y.4    Wang, R.5    Zhu, J.6
  • 26
    • 21644471608 scopus 로고    scopus 로고
    • Influence of the homogenisation procedure on the physicochemical properties of PLGA nanoparticles
    • Vandervoort J, Yoncheva K, Ludwig A. Influence of the homogenisation procedure on the physicochemical properties of PLGA nanoparticles. Chem. Pharm. Bull. (Tokyo) 52(11), 1273-1279 (2004).
    • (2004) Chem. Pharm. Bull. (Tokyo) , vol.52 , Issue.11 , pp. 1273-1279
    • Vandervoort, J.1    Yoncheva, K.2    Ludwig, A.3
  • 27
    • 51049120877 scopus 로고    scopus 로고
    • Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives
    • Uner M, Yener G. Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives. Int. J. Nanomed. 2(3), 289-300 (2007).
    • (2007) Int. J. Nanomed. , vol.2 , Issue.3 , pp. 289-300
    • Uner, M.1    Yener, G.2
  • 28
    • 0034196519 scopus 로고    scopus 로고
    • Effect of high-pressure homogenization on droplet size distributions and rheological properties of model oil-in-water emulsions
    • Floury J, Desrumaux A, Lardières J. Effect of high-pressure homogenization on droplet size distributions and rheological properties of model oil-in-water emulsions. Innovat. Food Sci. Emerg. Technol. 1(2), 127-134 (2000).
    • (2000) Innovat. Food Sci. Emerg. Technol. , vol.1 , Issue.2 , pp. 127-134
    • Floury, J.1    Desrumaux, A.2    Lardières, J.3
  • 29
    • 0342897023 scopus 로고    scopus 로고
    • Nanosuspensions for the formulation of poorly soluble drugs: I. Preparation by a size-reduction technique
    • Müller RH, Peters K. Nanosuspensions for the formulation of poorly soluble drugs: I. Preparation by a size-reduction technique. Int. J. Pharm. 160(2), 229-237 (1998).
    • (1998) Int. J. Pharm. , vol.160 , Issue.2 , pp. 229-237
    • Müller, R.H.1    Peters, K.2
  • 30
    • 34547956346 scopus 로고    scopus 로고
    • Poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles prepared by high pressure homogenization for paclitaxel chemotherapy
    • Dong Y, Feng S. Poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles prepared by high pressure homogenization for paclitaxel chemotherapy. Int. J. Pharm. 342(1-2), 208-214 (2007).
    • (2007) Int. J. Pharm. , vol.342 , Issue.1-2 , pp. 208-214
    • Dong, Y.1    Feng, S.2
  • 31
    • 77949416419 scopus 로고    scopus 로고
    • Preparation of curcumin sub-micrometer dispersions by high-pressure homogenization
    • Donsi F, Wang Y, Li J, Huang Q. Preparation of curcumin sub-micrometer dispersions by high-pressure homogenization. J. Agric. Food Chem. 58(5), 2848-2853 (2010).
    • (2010) J. Agric. Food Chem. , vol.58 , Issue.5 , pp. 2848-2853
    • Donsi, F.1    Wang, Y.2    Li, J.3    Huang, Q.4
  • 32
    • 78650778104 scopus 로고    scopus 로고
    • Preparation and characterization of intravenously injectable curcumin nanosuspension
    • Gao Y, Li Z, Sun M et al. Preparation and characterization of intravenously injectable curcumin nanosuspension. Drug Deliv. 18(2), 131-142 (2011).
    • (2011) Drug Deliv. , vol.18 , Issue.2 , pp. 131-142
    • Gao, Y.1    Li, Z.2    Sun, M.3
  • 33
    • 78650956365 scopus 로고    scopus 로고
    • Preparation and characterization of curcumin nanosuspension for enhanced solubility and dissolution velocity
    • Ravichandran R. Preparation and characterization of curcumin nanosuspension for enhanced solubility and dissolution velocity. Int. J. Nano Biomater. 3(2), 153 (2010).
    • (2010) Int. J. Nano Biomater. , vol.3 , Issue.2 , pp. 153
    • Ravichandran, R.1
  • 34
    • 77952321686 scopus 로고    scopus 로고
    • Development and validation of UPLC method for quality control of Curcuma longa Linn.: Fast simultaneous quantitation of three curcuminoids
    • Cheng J, Weijun K, Yun L et al. Development and validation of UPLC method for quality control of Curcuma longa Linn.: fast simultaneous quantitation of three curcuminoids. J. Pharm. Biomed. Anal. 53(1), 43-49 (2010).
    • (2010) J. Pharm. Biomed. Anal. , vol.53 , Issue.1 , pp. 43-49
    • Cheng, J.1    Weijun, K.2    Yun, L.3
  • 35
    • 0037161315 scopus 로고    scopus 로고
    • Vitamin e TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol®)
    • Mu L, Feng SS. Vitamin E TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol®). J. Control. Rel. 80(1-3), 129-144 (2002).
    • (2002) J. Control. Rel. , vol.80 , Issue.1-3 , pp. 129-144
    • Mu, L.1    Feng, S.S.2
  • 36
    • 0037151556 scopus 로고    scopus 로고
    • Preparation of cyclosporine A nanoparticles by evaporative precipitation into aqueous solution
    • Chen X, Young TJ, Sarkari M, Williams RO 3rd, Johnston KP. Preparation of cyclosporine A nanoparticles by evaporative precipitation into aqueous solution. Int. J. Pharm. 242(1-2), 3-14 (2002).
    • (2002) Int. J. Pharm. , vol.242 , Issue.1-2 , pp. 3-14
    • Chen, X.1    Young, T.J.2    Sarkari, M.3    Williams III, R.O.4    Johnston, K.P.5
  • 37
    • 79952534865 scopus 로고    scopus 로고
    • Formation of nanoemulsions stabilized by model food-grade emulsifiers using high-pressure homogenization: Factors affecting particle size
    • Qian C, McClements DJ. Formation of nanoemulsions stabilized by model food-grade emulsifiers using high-pressure homogenization: factors affecting particle size. Food Hydrocoll. 25(5), 1000-1008 (2011).
    • (2011) Food Hydrocoll. , vol.25 , Issue.5 , pp. 1000-1008
    • Qian, C.1    McClements, D.J.2
  • 38
    • 77954818105 scopus 로고    scopus 로고
    • Stability assessment of injectable castor oil-based nano-sized emulsion containing cationic droplets stabilized by poloxamer-chitosan emulsifier films
    • Tamilvanan S, Kumar BA, Senthilkumar SR, Baskar R, Sekharan TR. Stability assessment of injectable castor oil-based nano-sized emulsion containing cationic droplets stabilized by poloxamer-chitosan emulsifier films. AAPS Pharm. Sci. Tech. 11(2), 904-909 (2010).
    • (2010) AAPS Pharm. Sci. Tech. , vol.11 , Issue.2 , pp. 904-909
    • Tamilvanan, S.1    Kumar, B.A.2    Senthilkumar, S.R.3    Baskar, R.4    Sekharan, T.R.5
  • 39
    • 0023130497 scopus 로고
    • Surface characteristics and the interaction of colloidal particles with mouse peritoneal macrophages
    • Illum L, Jacobsen LO, Muller RH, Mak E, Davis SS. Surface characteristics and the interaction of colloidal particles with mouse peritoneal macrophages. Biomaterials 8(2), 113-117 (1987).
    • (1987) Biomaterials , vol.8 , Issue.2 , pp. 113-117
    • Illum, L.1    Jacobsen, L.O.2    Muller, R.H.3    Mak, E.4    Davis, S.S.5
  • 40
    • 0025296358 scopus 로고
    • Some determinants of morphology and release rate from poly(l)lactic acid microspheres
    • Kishida A, Dressman JB, Yoshioka S, Aso Y, Takeda Y. Some determinants of morphology and release rate from poly(l)lactic acid microspheres. J. Control. Rel. 13(1), 83-89 (1990).
    • (1990) J. Control. Rel. , vol.13 , Issue.1 , pp. 83-89
    • Kishida, A.1    Dressman, J.B.2    Yoshioka, S.3    Aso, Y.4    Takeda, Y.5
  • 41
    • 67349174236 scopus 로고    scopus 로고
    • Preparation and characterization of porous biodegradable microspheres used for controlled protein delivery
    • Sun L, Zhou S, Wang W, Li X, Wang J, Weng J. Preparation and characterization of porous biodegradable microspheres used for controlled protein delivery. Colloids Surf. A 345(1-3), 173-181 (2009).
    • (2009) Colloids Surf. A , vol.345 , Issue.1-3 , pp. 173-181
    • Sun, L.1    Zhou, S.2    Wang, W.3    Li, X.4    Wang, J.5    Weng, J.6
  • 42
    • 78650179651 scopus 로고    scopus 로고
    • Nano spray drying: A novel method for preparing protein nanoparticles for protein therapy
    • Lee SH, Heng D, Ng WK, Chan HK, Tan RB. Nano spray drying: a novel method for preparing protein nanoparticles for protein therapy. Int. J. Pharm. 403(1-2), 192-200 (2011).
    • (2011) Int. J. Pharm. , vol.403 , Issue.1-2 , pp. 192-200
    • Lee, S.H.1    Heng, D.2    Ng, W.K.3    Chan, H.K.4    Tan, R.B.5
  • 43
    • 33749526288 scopus 로고    scopus 로고
    • Effect of temperature-increase rate on drug release characteristics of dextran microspheres prepared by emulsion solvent evaporation process
    • Miyazaki Y, Onuki Y, Yakou S, Takayama K. Effect of temperature-increase rate on drug release characteristics of dextran microspheres prepared by emulsion solvent evaporation process. Int. J. Pharm. 324(2), 144-151 (2006).
    • (2006) Int. J. Pharm. , vol.324 , Issue.2 , pp. 144-151
    • Miyazaki, Y.1    Onuki, Y.2    Yakou, S.3    Takayama, K.4
  • 44
    • 0023557345 scopus 로고
    • The preparation and evaluation of drug-containing poly(d,l-lactide) microspheres formed by the solvent evaporation method
    • Bodmeier R, McGinity JW. The preparation and evaluation of drug-containing poly(d,l-lactide) microspheres formed by the solvent evaporation method. Pharm. Res. 4(6), 465-471 (1987).
    • (1987) Pharm. Res. , vol.4 , Issue.6 , pp. 465-471
    • Bodmeier, R.1    McGinity, J.W.2
  • 45
    • 33747149614 scopus 로고    scopus 로고
    • The effect of process variables on the morphology and release characteristics of protein-loaded PLGA particles
    • Yushu H, Venkatraman S. The effect of process variables on the morphology and release characteristics of protein-loaded PLGA particles. J. Appl. Polym. Sci. 101(5), 3053-3061 (2006).
    • (2006) J. Appl. Polym. Sci. , vol.101 , Issue.5 , pp. 3053-3061
    • Yushu, H.1    Venkatraman, S.2
  • 46
    • 77955665447 scopus 로고    scopus 로고
    • Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake
    • Yadav VR, Prasad S, Kannappan R et al. Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake. Biochem. Pharmacol. 80(7), 1021-1032 (2010).
    • (2010) Biochem. Pharmacol. , vol.80 , Issue.7 , pp. 1021-1032
    • Yadav, V.R.1    Prasad, S.2    Kannappan, R.3
  • 47
    • 77951525639 scopus 로고    scopus 로고
    • Cellular uptake and toxicity of gold nanoparticles in prostate cancer cells: A comparative study of rods and spheres
    • Arnida, Malugin A, Ghandehari H. Cellular uptake and toxicity of gold nanoparticles in prostate cancer cells: a comparative study of rods and spheres. J. Appl. Toxicol. 30(3), 212-217 (2010).
    • (2010) J. Appl. Toxicol. , vol.30 , Issue.3 , pp. 212-217
    • Arnida Malugin, A.1    Ghandehari, H.2
  • 48
    • 79751491160 scopus 로고    scopus 로고
    • The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells
    • Chen L, Mccrate JM, Lee JC, Li H. The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells. Nanotechnology 22(10), 105708 (2011).
    • (2011) Nanotechnology , vol.22 , Issue.10 , pp. 105708
    • Chen, L.1    McCrate, J.M.2    Lee, J.C.3    Li, H.4
  • 49
    • 50149110878 scopus 로고    scopus 로고
    • The effect of particle design on cellular internalization pathways
    • Gratton SE, Ropp PA, Pohlhaus PD et al. The effect of particle design on cellular internalization pathways. Proc. Natl Acad. Sci. USA 105(33), 11613-11618 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.33 , pp. 11613-11618
    • Gratton, S.E.1    Ropp, P.A.2    Pohlhaus, P.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.