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Volumn 7, Issue 12, 2012, Pages

Insulin Glargine and Cancer Risk in Patients with Diabetes: A Meta-Analysis

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN DERIVATIVE; INSULIN GLARGINE; ISOPHANE INSULIN;

EID: 84871301614     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051814     Document Type: Article
Times cited : (37)

References (45)
  • 1
    • 82955247909 scopus 로고    scopus 로고
    • IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030
    • Whiting DR, Guariguata L, Weil C, Shaw J, (2011) IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract 94: 311-321.
    • (2011) Diabetes Res Clin Pract , vol.94 , pp. 311-321
    • Whiting, D.R.1    Guariguata, L.2    Weil, C.3    Shaw, J.4
  • 2
    • 84855161991 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association
    • American Diabetes Association (2012) Diagnosis and classification of diabetes mellitus. Diabetes Care 35 Suppl 1: S64-71.
    • (2012) Diabetes Care , vol.35 , Issue.SUPPL. 1
  • 3
    • 0034117810 scopus 로고    scopus 로고
    • Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo
    • Heinemann L, Linkeschova R, Rave K, Hompesch B, Sedlak M, et al. (2000) Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo. Diabetes Care 23: 644-649.
    • (2000) Diabetes Care , vol.23 , pp. 644-649
    • Heinemann, L.1    Linkeschova, R.2    Rave, K.3    Hompesch, B.4    Sedlak, M.5
  • 4
    • 15944382350 scopus 로고    scopus 로고
    • Reduced hypoglycemia risk with insulin glargine: a meta-analysis comparing insulin glargine with human NPH insulin in type 2 diabetes
    • Rosenstock J, Dailey G, Massi-Benedetti M, Fritsche A, Lin Z, et al. (2005) Reduced hypoglycemia risk with insulin glargine: a meta-analysis comparing insulin glargine with human NPH insulin in type 2 diabetes. Diabetes Care 28: 950-955.
    • (2005) Diabetes Care , vol.28 , pp. 950-955
    • Rosenstock, J.1    Dailey, G.2    Massi-Benedetti, M.3    Fritsche, A.4    Lin, Z.5
  • 5
    • 68449094325 scopus 로고    scopus 로고
    • The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
    • Currie CJ, Poole CD, Gale EA, (2009) The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia 52: 1766-1777.
    • (2009) Diabetologia , vol.52 , pp. 1766-1777
    • Currie, C.J.1    Poole, C.D.2    Gale, E.A.3
  • 6
    • 68449104625 scopus 로고    scopus 로고
    • Insulin glargine use and short-term incidence of malignancies-a population-based follow-up study in Sweden
    • Jonasson JM, Ljung R, Talback M, Haglund B, Gudbjornsdottir S, et al. (2009) Insulin glargine use and short-term incidence of malignancies-a population-based follow-up study in Sweden. Diabetologia 52: 1745-1754.
    • (2009) Diabetologia , vol.52 , pp. 1745-1754
    • Jonasson, J.M.1    Ljung, R.2    Talback, M.3    Haglund, B.4    Gudbjornsdottir, S.5
  • 7
    • 68449094354 scopus 로고    scopus 로고
    • Use of insulin glargine and cancer incidence in Scotland: a study from the Scottish Diabetes Research Network Epidemiology Group
    • Colhoun HM, (2009) Use of insulin glargine and cancer incidence in Scotland: a study from the Scottish Diabetes Research Network Epidemiology Group. Diabetologia 52: 1755-1765.
    • (2009) Diabetologia , vol.52 , pp. 1755-1765
    • Colhoun, H.M.1
  • 8
    • 68449104156 scopus 로고    scopus 로고
    • Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study
    • Hemkens LG, Grouven U, Bender R, Gunster C, Gutschmidt S, et al. (2009) Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study. Diabetologia 52: 1732-1744.
    • (2009) Diabetologia , vol.52 , pp. 1732-1744
    • Hemkens, L.G.1    Grouven, U.2    Bender, R.3    Gunster, C.4    Gutschmidt, S.5
  • 9
    • 68449088664 scopus 로고    scopus 로고
    • Does diabetes therapy influence the risk of cancer?
    • Smith U, Gale EA, (2009) Does diabetes therapy influence the risk of cancer? Diabetologia 52: 1699-1708.
    • (2009) Diabetologia , vol.52 , pp. 1699-1708
    • Smith, U.1    Gale, E.A.2
  • 10
    • 79952279773 scopus 로고    scopus 로고
    • Risk of cancer in patients receiving insulin glargine
    • Dawson LK, Hamilton LA, (2010) Risk of cancer in patients receiving insulin glargine. Am J Health Syst Pharm 67: 2025-2031.
    • (2010) Am J Health Syst Pharm , vol.67 , pp. 2025-2031
    • Dawson, L.K.1    Hamilton, L.A.2
  • 11
    • 65549138380 scopus 로고    scopus 로고
    • Insulin analogues display IGF-I-like mitogenic and anti-apoptotic activities in cultured cancer cells
    • Weinstein D, Simon M, Yehezkel E, Laron Z, Werner H, (2009) Insulin analogues display IGF-I-like mitogenic and anti-apoptotic activities in cultured cancer cells. Diabetes Metab Res Rev 25: 41-49.
    • (2009) Diabetes Metab Res Rev , vol.25 , pp. 41-49
    • Weinstein, D.1    Simon, M.2    Yehezkel, E.3    Laron, Z.4    Werner, H.5
  • 12
    • 67650504265 scopus 로고    scopus 로고
    • Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines
    • Shukla A, Grisouard J, Ehemann V, Hermani A, Enzmann H, et al. (2009) Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines. Endocr Relat Cancer 16: 429-441.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 429-441
    • Shukla, A.1    Grisouard, J.2    Ehemann, V.3    Hermani, A.4    Enzmann, H.5
  • 13
    • 35848933452 scopus 로고    scopus 로고
    • IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts
    • Eckardt K, May C, Koenen M, Eckel J, (2007) IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts. Diabetologia 50: 2534-2543.
    • (2007) Diabetologia , vol.50 , pp. 2534-2543
    • Eckardt, K.1    May, C.2    Koenen, M.3    Eckel, J.4
  • 14
    • 24944566769 scopus 로고    scopus 로고
    • Insulin and its analogue glargine do not affect viability and proliferation of human coronary artery endothelial and smooth muscle cells
    • Staiger K, Staiger H, Schweitzer MA, Metzinger E, Balletshofer B, et al. (2005) Insulin and its analogue glargine do not affect viability and proliferation of human coronary artery endothelial and smooth muscle cells. Diabetologia 48: 1898-1905.
    • (2005) Diabetologia , vol.48 , pp. 1898-1905
    • Staiger, K.1    Staiger, H.2    Schweitzer, M.A.3    Metzinger, E.4    Balletshofer, B.5
  • 15
    • 48949085613 scopus 로고    scopus 로고
    • Characteristics of signalling properties mediated by long-acting insulin analogue glargine and detemir in target cells of insulin
    • Wada T, Azegami M, Sugiyama M, Tsuneki H, Sasaoka T, (2008) Characteristics of signalling properties mediated by long-acting insulin analogue glargine and detemir in target cells of insulin. Diabetes Res Clin Pract 81: 269-277.
    • (2008) Diabetes Res Clin Pract , vol.81 , pp. 269-277
    • Wada, T.1    Azegami, M.2    Sugiyama, M.3    Tsuneki, H.4    Sasaoka, T.5
  • 16
    • 77955171857 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG, (2010) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg 8: 336-341.
    • (2010) Int J Surg , vol.8 , pp. 336-341
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 17
    • 0034685429 scopus 로고    scopus 로고
    • Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group
    • Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, et al. (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 283: 2008-2012.
    • (2000) JAMA , vol.283 , pp. 2008-2012
    • Stroup, D.F.1    Berlin, J.A.2    Morton, S.C.3    Olkin, I.4    Williamson, G.D.5
  • 18
    • 43049113533 scopus 로고    scopus 로고
    • GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
    • Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, et al. (2008) GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 336: 924-926.
    • (2008) BMJ , vol.336 , pp. 924-926
    • Guyatt, G.H.1    Oxman, A.D.2    Vist, G.E.3    Kunz, R.4    Falck-Ytter, Y.5
  • 22
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG, (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21: 1539-1558.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 23
    • 84856715759 scopus 로고    scopus 로고
    • Risk of cancer in patients on insulin glargine and other insulin analogues in comparison with those on human insulin: results from a large population-based follow-up study
    • Ruiter R, Visser LE, van Herk-Sukel MP, Coebergh JW, Haak HR, et al. (2012) Risk of cancer in patients on insulin glargine and other insulin analogues in comparison with those on human insulin: results from a large population-based follow-up study. Diabetologia 55: 51-62.
    • (2012) Diabetologia , vol.55 , pp. 51-62
    • Ruiter, R.1    Visser, L.E.2    van Herk-Sukel, M.P.3    Coebergh, J.W.4    Haak, H.R.5
  • 24
    • 84856696946 scopus 로고    scopus 로고
    • Insulin glargine and risk of cancer: a cohort study in the French National Healthcare Insurance Database
    • Blin P, Lassalle R, Dureau-Pournin C, Ambrosino B, Bernard MA, et al. (2012) Insulin glargine and risk of cancer: a cohort study in the French National Healthcare Insurance Database. Diabetologia.
    • (2012) Diabetologia
    • Blin, P.1    Lassalle, R.2    Dureau-Pournin, C.3    Ambrosino, B.4    Bernard, M.A.5
  • 25
    • 84858674956 scopus 로고    scopus 로고
    • Glucose-lowering agents and the patterns of risk for cancer: a study with the General Practice Research Database and secondary care data
    • van Staa TP, Patel D, Gallagher AM, de Bruin ML, (2011) Glucose-lowering agents and the patterns of risk for cancer: a study with the General Practice Research Database and secondary care data. Diabetologia.
    • (2011) Diabetologia
    • van Staa, T.P.1    Patel, D.2    Gallagher, A.M.3    de Bruin, M.L.4
  • 26
    • 80054700909 scopus 로고    scopus 로고
    • Long-term effects of insulin glargine on the risk of breast cancer
    • Suissa S, Azoulay L, Dell'Aniello S, Evans M, Vora J, et al. (2011) Long-term effects of insulin glargine on the risk of breast cancer. Diabetologia 54: 2254-2262.
    • (2011) Diabetologia , vol.54 , pp. 2254-2262
    • Suissa, S.1    Azoulay, L.2    Dell'Aniello, S.3    Evans, M.4    Vora, J.5
  • 27
    • 84856701110 scopus 로고    scopus 로고
    • Further exploration of the relationship between insulin glargine and incident cancer: a retrospective cohort study of older Medicare patients
    • Morden NE, Liu SK, Smith J, Mackenzie TA, Skinner J, et al. (2011) Further exploration of the relationship between insulin glargine and incident cancer: a retrospective cohort study of older Medicare patients. Diabetes Care 34: 1965-1971.
    • (2011) Diabetes Care , vol.34 , pp. 1965-1971
    • Morden, N.E.1    Liu, S.K.2    Smith, J.3    Mackenzie, T.A.4    Skinner, J.5
  • 28
    • 79956143982 scopus 로고    scopus 로고
    • Insulin glargine use and short-term incidence of malignancies - a three-year population-based observation
    • Ljung R, Talback M, Haglund B, Jonasson JM, Gudbjornsdottir S, et al. (2011) Insulin glargine use and short-term incidence of malignancies- a three-year population-based observation. Acta Oncol 50: 685-693.
    • (2011) Acta Oncol , vol.50 , pp. 685-693
    • Ljung, R.1    Talback, M.2    Haglund, B.3    Jonasson, J.M.4    Gudbjornsdottir, S.5
  • 29
    • 79959603817 scopus 로고    scopus 로고
    • Cancer risk associated with insulin glargine among adult type 2 diabetes patients-a nationwide cohort study
    • Chang CH, Toh S, Lin JW, Chen ST, Kuo CW, et al. (2011) Cancer risk associated with insulin glargine among adult type 2 diabetes patients-a nationwide cohort study. PLoS One 6: e21368.
    • (2011) PLoS One , vol.6
    • Chang, C.H.1    Toh, S.2    Lin, J.W.3    Chen, S.T.4    Kuo, C.W.5
  • 30
    • 77954832956 scopus 로고    scopus 로고
    • Doses of insulin and its analogues and cancer occurrence in insulin-treated type 2 diabetic patients
    • Mannucci E, Monami M, Balzi D, Cresci B, Pala L, et al. (2010) Doses of insulin and its analogues and cancer occurrence in insulin-treated type 2 diabetic patients. Diabetes Care 33: 1997-2003.
    • (2010) Diabetes Care , vol.33 , pp. 1997-2003
    • Mannucci, E.1    Monami, M.2    Balzi, D.3    Cresci, B.4    Pala, L.5
  • 31
    • 68449088653 scopus 로고    scopus 로고
    • Similar risk of malignancy with insulin glargine and neutral protamine Hagedorn (NPH) insulin in patients with type 2 diabetes: findings from a 5 year randomised, open-label study
    • Rosenstock J, Fonseca V, McGill JB, Riddle M, Halle JP, et al. (2009) Similar risk of malignancy with insulin glargine and neutral protamine Hagedorn (NPH) insulin in patients with type 2 diabetes: findings from a 5 year randomised, open-label study. Diabetologia 52: 1971-1973.
    • (2009) Diabetologia , vol.52 , pp. 1971-1973
    • Rosenstock, J.1    Fonseca, V.2    McGill, J.B.3    Riddle, M.4    Halle, J.P.5
  • 32
    • 70450239958 scopus 로고    scopus 로고
    • Combined randomised controlled trial experience of malignancies in studies using insulin glargine
    • Home PD, Lagarenne P, (2009) Combined randomised controlled trial experience of malignancies in studies using insulin glargine. Diabetologia 52: 2499-2506.
    • (2009) Diabetologia , vol.52 , pp. 2499-2506
    • Home, P.D.1    Lagarenne, P.2
  • 33
    • 84864270406 scopus 로고    scopus 로고
    • Basal insulin and cardiovascular and other outcomes in dysglycemia
    • Gerstein HC, Bosch J, Dagenais GR, Diaz R, Jung H, et al. (2012) Basal insulin and cardiovascular and other outcomes in dysglycemia. N Engl J Med 367: 319-328.
    • (2012) N Engl J Med , vol.367 , pp. 319-328
    • Gerstein, H.C.1    Bosch, J.2    Dagenais, G.R.3    Diaz, R.4    Jung, H.5
  • 34
  • 35
    • 84861847187 scopus 로고    scopus 로고
    • Insulin Glargine: A Reevaluation of Rodent Carcinogenicity Findings
    • Stammberger I, Essermeant L, (2012) Insulin Glargine: A Reevaluation of Rodent Carcinogenicity Findings. Int J Toxicol.
    • (2012) Int J Toxicol
    • Stammberger, I.1    Essermeant, L.2
  • 36
    • 77952093575 scopus 로고    scopus 로고
    • Insulin glargine and insulin have identical effects on proliferation and phosphatidylinositol 3-kinase/AKT signalling in rat thyrocytes and human follicular thyroid cancer cells
    • Muller K, Weidinger C, Fuhrer D, (2010) Insulin glargine and insulin have identical effects on proliferation and phosphatidylinositol 3-kinase/AKT signalling in rat thyrocytes and human follicular thyroid cancer cells. Diabetologia 53: 1001-1003.
    • (2010) Diabetologia , vol.53 , pp. 1001-1003
    • Muller, K.1    Weidinger, C.2    Fuhrer, D.3
  • 37
    • 79960700555 scopus 로고    scopus 로고
    • Glargine promotes proliferation of breast adenocarcinoma cell line MCF-7 via AKT activation
    • Teng JA, Hou RL, Li DL, Yang RP, Qin J, (2011) Glargine promotes proliferation of breast adenocarcinoma cell line MCF-7 via AKT activation. Horm Metab Res 43: 519-523.
    • (2011) Horm Metab Res , vol.43 , pp. 519-523
    • Teng, J.A.1    Hou, R.L.2    Li, D.L.3    Yang, R.P.4    Qin, J.5
  • 38
    • 33947601038 scopus 로고    scopus 로고
    • Comparison of the mitogenic potency of regular human insulin and its analogue glargine in normal and transformed human breast epithelial cells
    • Staiger K, Hennige AM, Staiger H, Haring HU, Kellerer M, (2007) Comparison of the mitogenic potency of regular human insulin and its analogue glargine in normal and transformed human breast epithelial cells. Horm Metab Res 39: 65-67.
    • (2007) Horm Metab Res , vol.39 , pp. 65-67
    • Staiger, K.1    Hennige, A.M.2    Staiger, H.3    Haring, H.U.4    Kellerer, M.5
  • 39
    • 47049123594 scopus 로고    scopus 로고
    • Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-I
    • Liefvendahl E, Arnqvist HJ, (2008) Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-I. Hormone and Metabolic Research 40: 369-374.
    • (2008) Hormone and Metabolic Research , vol.40 , pp. 369-374
    • Liefvendahl, E.1    Arnqvist, H.J.2
  • 40
    • 48649108626 scopus 로고    scopus 로고
    • Proliferation of colo-357 pancreatic carcinoma cells and survival of patients with pancreatic carcinoma are not altered by insulin glargine
    • Erbel S, Reers C, Eckstein VW, Kleeff J, Buchler MW, et al. (2008) Proliferation of colo-357 pancreatic carcinoma cells and survival of patients with pancreatic carcinoma are not altered by insulin glargine. Diabetes Care 31: 1105-1111.
    • (2008) Diabetes Care , vol.31 , pp. 1105-1111
    • Erbel, S.1    Reers, C.2    Eckstein, V.W.3    Kleeff, J.4    Buchler, M.W.5
  • 41
    • 78650190900 scopus 로고    scopus 로고
    • Insulin glargine and NPH insulin increase to a similar degree epithelial cell proliferation and aberrant crypt foci formation in colons of diabetic mice
    • Nagel JM, Staffa J, Renner-Muller I, Horst D, Vogeser M, et al. (2010) Insulin glargine and NPH insulin increase to a similar degree epithelial cell proliferation and aberrant crypt foci formation in colons of diabetic mice. Horm Cancer 1: 320-330.
    • (2010) Horm Cancer , vol.1 , pp. 320-330
    • Nagel, J.M.1    Staffa, J.2    Renner-Muller, I.3    Horst, D.4    Vogeser, M.5
  • 42
    • 84871286324 scopus 로고    scopus 로고
    • Meta-analysis of insulin glargine and cancer risk: No evidence of increased risk of cancer
    • Boyle P, Koechlin A, Boffetta P, Boniol M, Bolli GB, (2011) Meta-analysis of insulin glargine and cancer risk: No evidence of increased risk of cancer. Diabetes 60: A356.
    • (2011) Diabetes , vol.60
    • Boyle, P.1    Koechlin, A.2    Boffetta, P.3    Boniol, M.4    Bolli, G.B.5
  • 43
    • 84867547480 scopus 로고    scopus 로고
    • Insulin glargine and risk of cancer: a meta-analysis
    • Du X, Zhang R, Xue Y, Li D, Cai J, et al. (2012) Insulin glargine and risk of cancer: a meta-analysis. Int J Biol Markers 27: e241-246.
    • (2012) Int J Biol Markers , vol.27
    • Du, X.1    Zhang, R.2    Xue, Y.3    Li, D.4    Cai, J.5
  • 44
    • 70949084349 scopus 로고    scopus 로고
    • No evidence of increased risk of malignancies in patients with diabetes treated with insulin detemir: a meta-analysis
    • Dejgaard A, Lynggaard H, Rastam J, Thomsen MK, (2009) No evidence of increased risk of malignancies in patients with diabetes treated with insulin detemir: a meta-analysis. Diabetologia 52: 2507-2512.
    • (2009) Diabetologia , vol.52 , pp. 2507-2512
    • Dejgaard, A.1    Lynggaard, H.2    Rastam, J.3    Thomsen, M.K.4
  • 45
    • 77953539812 scopus 로고    scopus 로고
    • Long-term metformin use is associated with decreased risk of breast cancer
    • Bodmer M, Meier C, Krahenbuhl S, Jick SS, Meier CR, (2010) Long-term metformin use is associated with decreased risk of breast cancer. Diabetes Care 33: 1304-1308.
    • (2010) Diabetes Care , vol.33 , pp. 1304-1308
    • Bodmer, M.1    Meier, C.2    Krahenbuhl, S.3    Jick, S.S.4    Meier, C.R.5


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