Strong and sustained effector function of memory- versus naïve-derived T cells upon T-cell receptor RNA transfer: Implications for cellular therapy

European Journal of Immunology

Volumn 42, Issue 12, 2012, Pages 3442-3453

  Thomas, Simone ^a   Klobuch, Sebastian ^a   Besold, Katrin ^a,c   Plachter, Bodo ^a   Dörrie, Jan ^b   Schaft, Niels ^b   Theobald, Matthias ^a   Herr, Wolfgang ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Cytomegalovirus; Memory T cells; Naive T cells; RNA; T cell receptor

Indexed keywords

ANTIGEN; BINDING PROTEIN; CYTOMEGALOVIRUS ANTIGEN PP65; HLA A ANTIGEN; RNA; T LYMPHOCYTE RECEPTOR;

ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL LINE; CELL THERAPY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOLYSIS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; ELECTROPORATION; FIBROBLAST; GENE EXPRESSION; GENETIC ENGINEERING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE FUNCTION; MEMORY CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RNA TRANSLATION; RNA TRANSPORT; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; VIRUS STRAIN;

CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; ELECTROPORATION; FIBROBLASTS; GENE EXPRESSION REGULATION; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA-A2 ANTIGEN; HUMANS; IMMUNOLOGIC MEMORY; PHOSPHOPROTEINS; RECEPTORS, ANTIGEN, T-CELL; RNA; TISSUE THERAPY; TRANSFECTION; TRANSPLANTATION, HOMOLOGOUS; VIRAL MATRIX PROTEINS;

EID: 84871296306     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242666     Document Type: Article

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