메뉴 건너뛰기




Volumn 145, Issue 1, 2013, Pages 162-167

Aged garlic extract restores nitric oxide bioavailability in cultured human endothelial cells even under conditions of homocysteine elevation

Author keywords

Aged garlic extract; Antioxidant; Endothelium; Homocysteine; Nitric oxide; Tetrahydrobiopterin

Indexed keywords

AGED GARLIC EXTRACT; AMINOPTERIN; CYSTEINE; FLUORESCENT DYE; GARLIC EXTRACT; GLUTATHIONE; HOMOCYSTEINE; HYPOXANTHINE; METHIONINE; NITRIC OXIDE SYNTHASE; TETRAHYDROBIOPTERIN; THYMIDINE; UNCLASSIFIED DRUG;

EID: 84871289805     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.10.045     Document Type: Article
Times cited : (38)

References (51)
  • 1
    • 33644835000 scopus 로고    scopus 로고
    • Clarifying the real bioactive constituents of garlic
    • H. Amagase Clarifying the real bioactive constituents of garlic Journal of Nutrition 136 2006 716S 725S
    • (2006) Journal of Nutrition , vol.136
    • Amagase, H.1
  • 3
    • 84871280662 scopus 로고    scopus 로고
    • Anonymus, Garlic Fluidextract USP 28-NF 23 Rockville, Md, United States Pharmacopeia
    • Anonymus, Garlic Fluidextract USP 28-NF 23, In, United States Pharmacopoeia (USP) 28 - National Formula (NF) 23 Rockville, Md, United States Pharmacopeia, 2005: 2089-2090.
    • (2005) United States Pharmacopoeia (USP) 28 - National Formula (NF) , vol.23 , pp. 2089-2090
  • 6
    • 0036710777 scopus 로고    scopus 로고
    • Total plasma homocysteine level and risk of cardiovascular disease: A meta-analysis of prospective cohort studies
    • L.E. Bautista, I.A. Arenas, A. Penuela, and L.X. Martinez Total plasma homocysteine level and risk of cardiovascular disease: a meta-analysis of prospective cohort studies Journal of Clinical Epidemiology 55 2002 882 887
    • (2002) Journal of Clinical Epidemiology , vol.55 , pp. 882-887
    • Bautista, L.E.1    Arenas, I.A.2    Penuela, A.3    Martinez, L.X.4
  • 8
    • 4744340348 scopus 로고    scopus 로고
    • Inhibiting progression of coronary calcification using aged garlic extract in patients receiving statin therapy: A preliminary study
    • M.J. Budoff, J. Takasu, F.R. Flores, Y. Niihara, B. Lu, B.H. Lau, R.T. Rosen, and H. Amagase Inhibiting progression of coronary calcification using aged garlic extract in patients receiving statin therapy: a preliminary study Preventive Medicine 39 2004 985 991
    • (2004) Preventive Medicine , vol.39 , pp. 985-991
    • Budoff, M.J.1    Takasu, J.2    Flores, F.R.3    Niihara, Y.4    Lu, B.5    Lau, B.H.6    Rosen, R.T.7    Amagase, H.8
  • 9
    • 33644860498 scopus 로고    scopus 로고
    • Aged garlic extract retards progression of coronary artery calcification
    • M. Budoff Aged garlic extract retards progression of coronary artery calcification Journal of Nutrition 136 2006 741S 744S
    • (2006) Journal of Nutrition , vol.136
    • Budoff, M.1
  • 10
    • 70349295182 scopus 로고    scopus 로고
    • Aged garlic extract supplemented with B vitamins, folic acid and l-arginine retards the progression of subclinical atherosclerosis: A randomized clinical trial
    • M.J. Budoff, N. Ahmadi, K.M. Gul, S.T. Liu, F.R. Flores, J. Tiano, J. Takasu, E. Miller, and S. Tsimikas Aged garlic extract supplemented with B vitamins, folic acid and l-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial Preventive Medicine 49 2009 101 107
    • (2009) Preventive Medicine , vol.49 , pp. 101-107
    • Budoff, M.J.1    Ahmadi, N.2    Gul, K.M.3    Liu, S.T.4    Flores, F.R.5    Tiano, J.6    Takasu, J.7    Miller, E.8    Tsimikas, S.9
  • 13
    • 0035321614 scopus 로고    scopus 로고
    • Homocysteine lowering effect of different multivitamin preparations in patients with end-stage renal disease
    • J. Dierkes, U. Domrose, K.P. Bosselmann, K.H. Neumann, and C. Luley Homocysteine lowering effect of different multivitamin preparations in patients with end-stage renal disease Journal of Renal Nutrition 11 2001 67 72
    • (2001) Journal of Renal Nutrition , vol.11 , pp. 67-72
    • Dierkes, J.1    Domrose, U.2    Bosselmann, K.P.3    Neumann, K.H.4    Luley, C.5
  • 14
    • 0036173215 scopus 로고    scopus 로고
    • Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women
    • S.A. Dillon, G.M. Lowe, D. Billington, and K. Rahman Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women Journal of Nutrition 132 2002 168 171
    • (2002) Journal of Nutrition , vol.132 , pp. 168-171
    • Dillon, S.A.1    Lowe, G.M.2    Billington, D.3    Rahman, K.4
  • 16
    • 0030832441 scopus 로고    scopus 로고
    • The effect of the aged garlic extract, 'Kyolic', on the development of experimental atherosclerosis
    • J.L. Efendy, D.L. Simmons, G.R. Campbell, and J.H. Campbell The effect of the aged garlic extract, 'Kyolic', on the development of experimental atherosclerosis Atherosclerosis 132 1997 37 42
    • (1997) Atherosclerosis , vol.132 , pp. 37-42
    • Efendy, J.L.1    Simmons, D.L.2    Campbell, G.R.3    Campbell, J.H.4
  • 18
    • 33645780634 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase in vascular disease: From marvel to menace
    • U. Forstermann, and T. Munzel Endothelial nitric oxide synthase in vascular disease: from marvel to menace Circulation 113 2006 1708 1714
    • (2006) Circulation , vol.113 , pp. 1708-1714
    • Forstermann, U.1    Munzel, T.2
  • 19
    • 0018868814 scopus 로고
    • Analysis of reduced forms of biopterin in biological tissues and fluids
    • T. Fukushima, and J.C. Nixon Analysis of reduced forms of biopterin in biological tissues and fluids Analytical Biochemistry 102 1980 176 188
    • (1980) Analytical Biochemistry , vol.102 , pp. 176-188
    • Fukushima, T.1    Nixon, J.C.2
  • 22
    • 1242271188 scopus 로고    scopus 로고
    • L-Homocysteine and l-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells
    • S.J. Heydrick, N. Weiss, S.R. Thomas, A.P. Cap, D.R. Pimentel, J. Loscalzo, and J.F. Keaney Jr. l-Homocysteine and l-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells Free Radical Biology & Medicine 36 2004 632 640
    • (2004) Free Radical Biology & Medicine , vol.36 , pp. 632-640
    • Heydrick, S.J.1    Weiss, N.2    Thomas, S.R.3    Cap, A.P.4    Pimentel, D.R.5    Loscalzo, J.6    Keaney Jr., J.F.7
  • 24
  • 25
    • 0032939041 scopus 로고    scopus 로고
    • S-allylcysteine attenuates oxidative stress in endothelial cells
    • N. Ide, and B.H. Lau S-allylcysteine attenuates oxidative stress in endothelial cells Drug Development and Industrial Pharmacy 25 1999 619 624
    • (1999) Drug Development and Industrial Pharmacy , vol.25 , pp. 619-624
    • Ide, N.1    Lau, B.H.2
  • 26
    • 0035126519 scopus 로고    scopus 로고
    • Garlic compounds minimize intracellular oxidative stress and inhibit nuclear factor-kappa b activation
    • N. Ide, and B.H. Lau Garlic compounds minimize intracellular oxidative stress and inhibit nuclear factor-kappa b activation Journal of Nutrition 131 2001 1020S 1026S
    • (2001) Journal of Nutrition , vol.131
    • Ide, N.1    Lau, B.H.2
  • 28
    • 0035126584 scopus 로고    scopus 로고
    • Suppression of LDL oxidation by garlic
    • B.H. Lau Suppression of LDL oxidation by garlic Journal of Nutrition 131 2001 985S 988S
    • (2001) Journal of Nutrition , vol.131
    • Lau, B.H.1
  • 29
    • 0035812887 scopus 로고    scopus 로고
    • Reliable in vitro measurement of nitric oxide released from endothelial cells using low concentrations of the fluorescent probe 4,5-diaminofluorescein
    • J.F. Leikert, T.R. Rathel, C. Muller, A.M. Vollmar, and V.M. Dirschl Reliable in vitro measurement of nitric oxide released from endothelial cells using low concentrations of the fluorescent probe 4,5-diaminofluorescein Federation of European Biochemical Societies Letters 506 2001 131 134
    • (2001) Federation of European Biochemical Societies Letters , vol.506 , pp. 131-134
    • Leikert, J.F.1    Rathel, T.R.2    Muller, C.3    Vollmar, A.M.4    Dirschl, V.M.5
  • 30
    • 0036834582 scopus 로고    scopus 로고
    • Effects of vitamin e on cardiovascular and microvascular outcomes in high-risk patients with diabetes: Results of the HOPE study and MICRO-HOPE substudy
    • E. Lonn, S. Yusuf, B. Hoogwerf, J. Pogue, Q. Yi, B. Zinman, J. Bosch, G. Dagenais, J.F. Mann, and H.C. Gerstein Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: results of the HOPE study and MICRO-HOPE substudy Diabetes Care 25 2002 1919 1927
    • (2002) Diabetes Care , vol.25 , pp. 1919-1927
    • Lonn, E.1    Yusuf, S.2    Hoogwerf, B.3    Pogue, J.4    Yi, Q.5    Zinman, B.6    Bosch, J.7    Dagenais, G.8    Mann, J.F.9    Gerstein, H.C.10
  • 32
    • 33746341829 scopus 로고    scopus 로고
    • Aged garlic extract inhibits peroxynitrite-induced hemolysis
    • N. Morihara, N. Ide, I. Sumioka, and E. Kyo Aged garlic extract inhibits peroxynitrite-induced hemolysis Redox Report 10 2005 159 165
    • (2005) Redox Report , vol.10 , pp. 159-165
    • Morihara, N.1    Ide, N.2    Sumioka, I.3    Kyo, E.4
  • 33
    • 30344443934 scopus 로고    scopus 로고
    • Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: Role of nitric oxide and p53
    • A.S. Mousa, and S.A. Mousa Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53 Nutrition and Cancer 53 2005 104 110
    • (2005) Nutrition and Cancer , vol.53 , pp. 104-110
    • Mousa, A.S.1    Mousa, S.A.2
  • 34
    • 35448972133 scopus 로고    scopus 로고
    • Vascular oxidant stress and inflammation in hyperhomocysteinemia
    • L. Papatheodorou, and N. Weiss Vascular oxidant stress and inflammation in hyperhomocysteinemia Antioxidants & Redox Signaling 9 2007 1941 1958
    • (2007) Antioxidants & Redox Signaling , vol.9 , pp. 1941-1958
    • Papatheodorou, L.1    Weiss, N.2
  • 36
    • 0033751670 scopus 로고    scopus 로고
    • Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans
    • K. Rahman, and D. Billington Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans Journal of Nutrition 130 2000 2662 2665
    • (2000) Journal of Nutrition , vol.130 , pp. 2662-2665
    • Rahman, K.1    Billington, D.2
  • 37
    • 0035127029 scopus 로고    scopus 로고
    • N alpha-(1-deoxy-d-fructos-1-yl)-l-arginine, an antioxidant compound identified in aged garlic extract
    • K. Ryu, N. Ide, H. Matsuura, and Y. Itakura N alpha-(1-deoxy-d-fructos-1- yl)-l-arginine, an antioxidant compound identified in aged garlic extract Journal of Nutrition 131 2001 972S 976S
    • (2001) Journal of Nutrition , vol.131
    • Ryu, K.1    Ide, N.2    Matsuura, H.3    Itakura, Y.4
  • 39
    • 0037465546 scopus 로고    scopus 로고
    • The antioxidant acetylcysteine reduces cardiovascular events in patients with end-stage renal failure: A randomized, controlled trial
    • M. Tepel, M. van der Giet, M. Statz, J. Jankowski, and W. Zidek The antioxidant acetylcysteine reduces cardiovascular events in patients with end-stage renal failure: a randomized, controlled trial Circulation 107 2003 992 995
    • (2003) Circulation , vol.107 , pp. 992-995
    • Tepel, M.1    Van Der Giet, M.2    Statz, M.3    Jankowski, J.4    Zidek, W.5
  • 42
    • 70249093891 scopus 로고    scopus 로고
    • Tetrahydrobiopterin, superoxide, and vascular dysfunction
    • J. Vasquez-Vivar Tetrahydrobiopterin, superoxide, and vascular dysfunction Free Radical Biology & Medicine 47 2009 1108 1119
    • (2009) Free Radical Biology & Medicine , vol.47 , pp. 1108-1119
    • Vasquez-Vivar, J.1
  • 43
    • 0037926903 scopus 로고    scopus 로고
    • Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein e double knock-out mice with and without dietary perturbation
    • H. Wang, X. Jiang, F. Yang, J.W. Gaubatz, L. Ma, M.J. Magera, X. Yang, P.B. Berger, W. Durante, H.J. Pownall, and A.I. Schafer Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation Blood 101 2003 3901 3907
    • (2003) Blood , vol.101 , pp. 3901-3907
    • Wang, H.1    Jiang, X.2    Yang, F.3    Gaubatz, J.W.4    Ma, L.5    Magera, M.J.6    Yang, X.7    Berger, P.B.8    Durante, W.9    Pownall, H.J.10    Schafer, A.I.11
  • 44
    • 34249730020 scopus 로고    scopus 로고
    • Efficacy of folic acid supplementation in stroke prevention: A meta-analysis
    • X. Wang, X. Qin, H. Demirtas, J. Li, G. Mao, Y. Huo, N. Sun, L. Liu, and X. Xu Efficacy of folic acid supplementation in stroke prevention: a meta-analysis Lancet 369 2007 1876 1882
    • (2007) Lancet , vol.369 , pp. 1876-1882
    • Wang, X.1    Qin, X.2    Demirtas, H.3    Li, J.4    Mao, G.5    Huo, Y.6    Sun, N.7    Liu, L.8    Xu, X.9
  • 45
    • 14044276314 scopus 로고    scopus 로고
    • Mechanisms of increased vascular oxidant stress in hyperhomocysteinemia and its impact on endothelial function
    • N. Weiss Mechanisms of increased vascular oxidant stress in hyperhomocysteinemia and its impact on endothelial function Current Drug Metabolism 6 2005 27 36
    • (2005) Current Drug Metabolism , vol.6 , pp. 27-36
    • Weiss, N.1
  • 47
    • 33644836981 scopus 로고    scopus 로고
    • Aged garlic extract improves homocysteine-induced endothelial dysfunction in macro- and microcirculation
    • N. Weiss, N. Ide, T. Abahji, L. Nill, C. Keller, and U. Hoffmann Aged garlic extract improves homocysteine-induced endothelial dysfunction in macro- and microcirculation Journal of Nutrition 136 2006 750S 754S
    • (2006) Journal of Nutrition , vol.136
    • Weiss, N.1    Ide, N.2    Abahji, T.3    Nill, L.4    Keller, C.5    Hoffmann, U.6
  • 51
    • 0034688195 scopus 로고    scopus 로고
    • Vitamin e supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • S. Yusuf, G. Dagenais, J. Pogue, J. Bosch, and P. Sleight Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators New England Journal of Medicine 342 2000 154 160
    • (2000) New England Journal of Medicine , vol.342 , pp. 154-160
    • Yusuf, S.1    Dagenais, G.2    Pogue, J.3    Bosch, J.4    Sleight, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.