Functional ectodomain of the hemagglutinin-neuraminidase protein is expressed in transgenic tobacco cells as a candidate vaccine against Newcastle disease virus

Plant Cell, Tissue and Organ Culture

Volumn 112, Issue 1, 2013, Pages 117-121

  Lai, Kok Song ^a   Yusoff, Khatijah ^a   Mahmood, Maziah ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Hemagglutinin neuraminidase; Newcastle disease virus; NtADH 5 UTR; Plant based vaccine

Indexed keywords

BY-2 CELL; CAULIFLOWER MOSAIC VIRUS; CYTOSOLS; ECTODOMAIN; HEMAGGLUTININ-NEURAMINIDASE; IMMUNE RESPONSE; IMMUNOBLOTTING; NICOTIANA TABACUM; REAL-TIME PCR; TOTAL SOLUBLE PROTEIN; TRANSGENIC LINES; TRANSGENIC TOBACCO; UNTRANSLATED REGIONS;

CELL CULTURE; CELLS; PLANTS (BOTANY); POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; TOBACCO; VACCINES; VIRUSES;

DISEASES;

CAULIFLOWER MOSAIC VIRUS; MUS; NEWCASTLE DISEASE VIRUS; NICOTIANA; NICOTIANA TABACUM;

EID: 84871289669     PISSN: 01676857     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11240-012-0214-x     Document Type: Article

References (21)

1. Berinstein A, Rovere CV, Asurmendi S, Gómez E, Zanetti F, Zabal O, Tozzini A, Grand DC, Toboga O, Calmante G, Barrios H, Hopp E, Carillo E (2005) Mucosal and systemic immunization elicited by Newcastle disease virus (NDV) transgenic plants as antigens. Vaccine 23: 5583-5589.
2. Faye L, Boulaflous A, Benchabane M, Gomord V, Michaud D (2005) Protein modifications in plant secretory pathway: current status and practical implications in molecular pharming. Vaccine 23: 1770-1778.
3. Girard L, Bastin M, Courtois D (2004) Expression of the human milk protein sCD14 in tobacco plant cell culture. Plant Cell Tissue Organ Cult 78: 253-260.
4. Gómez E, Zoth SC, Asurmendi S, Rovere CV, Berinstein A (2009) Expression of hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus in agroinfiltrated Nicotiana benthamiana plants. J Biotechnol 144: 337-340.
5. Haasen D, Kohler C, Neuhaus G, Merkle T (1999) Nuclear export of proteins in plants: AtXPO1 is the export receptor for leucine-rich nuclear export signals in Arabidopsis thaliana. Plant J 20: 695-705.
6. Hahn BS, Jeon IS, Jung YJ, Kim JB, Parl JS, Ha SH, Kim KH, Kim HM, Yang JS, Kim YH (2007) Expression of hemagglutinin-neuraminidase protein of Newcastle disease virus in transgenic tobacco. Plant Biotechnol Rep 1: 85-92.
7. Ko K, Koprowski H (2005) Plant biopharming of monoclonal antibodies. Virus Res 111: 93-100.
8. Martínez CA, Giulietti AM, Rodríguez Talou J (2011) Expression of a KDEL-tagged dengue virus protein in cell suspension cultures of Nicotiana tabacum and Morinda citrifolia. Plant Cell Tissue Organ Cult 107: 91-100.
9. Matsui T, Hori M, Shizawa N, Nakayama H, Shinmyo A, Yoshida K (2006) High-efficiency secretory production of peroxidase C1a using vesicular transport engineering in transgenic tobacco. J Biosci Bioeng 102: 102-109.
10. Matsui T, Asao H, Ki M, Sawada K, Kato K (2009) Transgenic lettuce producing a candidate protein for vaccine against edema disease. Biosci Biotechnol Biochem 73: 1628-1634.
11. Nakayama H, Yoshida K, Ono H, Murooka Y, Shinmyo A (2000) Ectoine, the compatible solute of Halomonas elongata, confers hyperosmotic tolerance in cultured tobacco cells. Plant Physiol 122: 1239-1246.
12. Obembe OO, Popoola JO, Leelavathi S, Reddy SV (2010) Advances in plant molecular farming. Biotechnol Adv 29: 210-222.
13. Ong HKA, Ali AM, Omar AR, Yusoff K (2000) Cloning and expression of the HN gene from velogenic viscerotropic Newcastle disease virus strain AF2240 in Sf9 insect cells. Cytotechnology 32: 243-251.
14. Pires AS, Rosa S, Castanheira S, Fevereiro P, Abranches R (2012) Expression of a recombinant human erythropoietin in suspension cultures of Arabidopsis, tobacco and Medicago. Plant Cell Tissue Organ Cult. doi: 10. 1007/s11240-012-0141-x.
15. Satoh J, Kato K, Shinmyo A (2004) The 5′-untranslated region of the tobacco alcohol dehydrogenase gene functions as an effective translational enhancer in plant. J Biosci Bioeng 98: 1-8.
16. Soria-Guerra RE, Moreno-Fierros L, Roslaes-Mendoza S (2011) Two decades of plant-based candidates vaccine: a review of the chimeric protein approaches. Plant Cell Rep 30: 1367-1382.
17. Sorrentino A, Schillberg S, Fisher R, Rao R, Porta R, Mariniello L (2005) Recombinant human tissue transglutaminase produced into tobacco suspension cell cultures is active and recognizes autoantibodies in the serum of coeliac patients. Int J Biochem Cell Biol 37: 842-851.
18. Sun QY, Ding LW, Lomomossoff GP, Sun YB, Luo M, Li CQ, Jiang L, Xu ZF (2011) Improved expression and purification of recombinant human serum albumin from transgenic tobacco suspension culture. J Biotechnol 155: 164-172.
19. Urreta I, Oyanguren I, Castanón S (2011) Tobacco as biofactory for biologically active hPL production: a human hormone with the potential applications in type-1 diabetes. Transgenic Res 20: 721-733.
20. Wong SK, Tan WS, Omar AR, Tan CS, Yusoff K (2009) Immunogenic properties of recombinant ectodomian of Newcastle disease virus hemagglutinin-neuraminidase protein expressed in Escherichia coli. Act Virol 53: 35-41.
21. Yusoff K, Tan WS (2001) Newcastle disease virus: macromolecules and opportunities. Avian Pathol 30: 439-455.