Stem cells from human exfoliated deciduous tooth-derived conditioned medium enhance recovery of focal cerebral ischemia in rats

Tissue Engineering - Part A

Volumn 19, Issue 1-2, 2013, Pages 24-29

  Inoue, Takanori ^a   Sugiyama, Masahiko ^a   Hattori, Hisashi ^a   Wakita, Hideaki ^b   Wakabayashi, Toshihiko ^a   Ueda, Minoru ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN INJURY; CEREBRAL ISCHEMIA; CONDITIONED MEDIUM; DECIDUOUS TEETH; DENTAL PULP; FUNCTIONAL RECOVERY; ISCHEMIC TISSUES; MIDDLE CEREBRAL ARTERY; MOTOR FUNCTION; NEUROFILAMENTS; NEUROGENESIS; POSITIVE SIGNALS; PROGENITOR CELL; RAT BRAIN; SPRAGUE-DAWLEY RATS; VASCULOGENESIS;

ENDOTHELIAL CELLS; RATS; STEM CELLS; TISSUE;

MOLECULAR BIOLOGY;

RATTUS;

ANIMAL; ARTICLE; BRAIN ISCHEMIA; CONVALESCENCE; CYTOLOGY; DECIDUOUS TOOTH; HUMAN; MALE; METHODOLOGY; PATHOLOGY; RAT; SPRAGUE DAWLEY RAT; STEM CELL TRANSPLANTATION; TRANSPLANTATION; TREATMENT OUTCOME;

ANIMALS; BRAIN ISCHEMIA; HUMANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; STEM CELL TRANSPLANTATION; TOOTH, DECIDUOUS; TREATMENT OUTCOME;

EID: 84871285621     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2011.0385     Document Type: Article

References (21)

1. Donnan G.A., Fisher, M., Macleod, M., and Davis, S.M. Stroke. Lancet 371, 1612, 2008.
2. Honmou, O., Houkin, K., Matsunaga, T., Niitsu, Y., Ishiai, S., Onodera, R., Waxman, S.G., and Kocsis, J.D. Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke. Brain 134, 1790, 2011.
3. Bang, O.Y., Lee, J.S., Lee, P.H., and Lee, G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol 57, 874, 2005.
4. Kern, S., Eichler, H., Stoeve, J., Klu ter, H., and Bieback, K. Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 24, 1294, 2006.
5. Nakamura, S., Yamada, Y., Katagiri, W., Sugito, T., Ito, K., and Ueda, M. Stem cell proliferation pathways comparison between human exfoliated deciduous teeth and dental pulp stem cells by gene expression profile from promising dental pulp. J Endod 35, 1536, 2009.
6. Pierdomenico, L., Bonsi, L., Calvitti, M., Rondelli, D., Arpinati, M., Chirumbolo, G., Becchetti, E., Marchionni, C., Alviano, F., Fossati, V., Staffolani, N., Franchina, M., Grossi, A., and Bagnara, G.P. Multipotent mesenchymal stem cells with immunosuppressive activity can be easily isolated from dental pulp. Transplantation 80, 836, 2005.
7. Sugiyama, M., Iohara, K., Wakita, H., Hattori, H., Ueda, M., Matsushita, K., and Nakashima, M. Dental pulp-derived CD31{/CD146{ side population stem/progenitor cells enhance recovery of focal cerebral ischemia in rats. Tissue Eng Part A 17, 1303, 2011.
8. Nicaise, C., Mitrecic, D., and Pochet, R. Brain and spinal cord affected by amyotrophic lateral sclerosis induce differential growth factors expression in rat mesenchymal and neural stem cells. Neuropathol Appl Neurobiol 37,179, 2011.
9. Illum, L. Transport of drugs from the nasal cavity to the central nervous system. Eur J Pharm Sci 11, 1, 2000.
10. Thorne, R.G. and Frey, W.H. 2nd. Delivery of neurotrophic factors to the central nervous system: Pharmacokinetic considerations. Clin Pharmacokinet 40, 907, 2001.
11. Yang, J.P., Liu, H.J., Wang, Z.L., Cheng, S.M., Cheng, X., Xu, G.L., and Liu, X.F. The dose-effectiveness of intranasal VEGF in treatment of experimental stroke. Neurosci Lett 461, 212, 2009.
12. Gronthos, S., Mankai, M., Brahim, J., Robey, P.G., and Shi, S. Postnatal human dental pulp stem cells (DPSC) in vitro and in vivo. Proc Natl Acad Sci U S A 97, 13625, 2000.
13. Miura, M., Gronthos, S., Zhao, M., Lu, B., Fisher, L.W., Robey, P.G., and Shi, S. SHED: Stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci U S A 100, 5807, 2003.
14. Longa, E.Z., Weinstein, P.R., Carlson, S., and Cummins, R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20, 84, 1989.
15. Leker, R.R., Gai, N., Mechoulam, R., and Ovadia, H. Druginduced hypothermia reduces ischemic damage: Effects of the cannabinoid HU-210. Stroke 34, 2000, 2003.
16. Ginsberg, M.D. Adventures in the pathophysiology of brain ischemia: Penumbra, gene expression, neuroprotection: The 2002 Thomas Willis Lecture. Stroke 34, 214, 2003.
17. Leach, M.J, Swan, J.H, Eisenthal, D., Dopson, M., and Nobbs, M. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke 24, 1063, 1993.
18. Ooi, A.T., Mah, V., Nickerson, D.W., Gilbert, J.L., Ha, V.L., Hegab, A.E., Horvath, S., Alavi, M., Maresh, E.L., Chia, D., Gower, A.C., Lenburg, M.E., Spira, A., Solis, L.M., Wistuba, I.I., Walser, T.C., Wallace, W.D., Dubinett, S.M., Goodglick, L., and Gomperts, B.N. Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Res 70, 6639, 2010.
19. Frisén, J., Johansson, C.B., Toro k, C., Risling, M., and Lendahl, U. Rapid, widespread, and longlasting induction of nestin contributes to the generation of glial scar tissue after CNS injury. J Cell Biol 131, 453, 1995.
20. Itoh, T., Satou, T., Takemori, K., Hashimoto, S., and Ito, H. Neural stem cells and new neurons in the cerebral cortex of stroke-prone spontaneously hypertensive rats after stroke. J Mol Neurosci 41, 55, 2010.
21. Thorne, R.G., Pronk, G.J., Padmanabhan, V., and Frey, W.H. nd. Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration. Neuroscience 127, 481, 2004.