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Volumn 31, Issue 2, 2012, Pages 121-129

Diosgenin, a steroidal saponin, exhibits anticancer activity by attenuating lipid peroxidation via enhancing antioxidant defense system during NMU induced breast carcinoma

Author keywords

Antioxidants; Breast cancer; Diosgenin; LPO; Marker enzymes; NMU

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA TOCOPHEROL; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; CATALASE; DIOSGENIN; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

EID: 84871278864     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: 10.1615/JEnvironPatholToxicolOncol.v31.i2.40     Document Type: Article
Times cited : (41)

References (31)
  • 2
    • 0028785824 scopus 로고
    • Rapid induction of mammary intraductal proliferation, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea
    • Thompson HJ, McGinley JN, Rothhammer K, Singh M. Rapid induction of mammary intraductal proliferation, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea. Carcinogenesis. 1995;16:2407-2411.
    • (1995) Carcinogenesis , vol.16 , pp. 2407-2411
    • Thompson, H.J.1    McGinley, J.N.2    Rothhammer, K.3    Singh, M.4
  • 3
    • 32444433056 scopus 로고    scopus 로고
    • Cellular aspects of photocarcinogenesis
    • Nishigori C. Cellular aspects of photocarcinogenesis. Photochem Photobiol Sci. 2006;5:208-214.
    • (2006) Photochem Photobiol Sci , vol.5 , pp. 208-214
    • Nishigori, C.1
  • 4
    • 77953287129 scopus 로고    scopus 로고
    • Chemopreventive potential of ferulic acid in 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in Sprague-Dawley rats
    • Baskaran N, Manoharan S, Balakrishnan S, Pugalendhi P. Chemopreventive potential of ferulic acid in 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in Sprague-Dawley rats. Eur J Pharmacol. 2010;637:22-29.
    • (2010) Eur J Pharmacol , vol.637 , pp. 22-29
    • Baskaran, N.1    Manoharan, S.2    Balakrishnan, S.3    Pugalendhi, P.4
  • 5
  • 6
    • 33947447885 scopus 로고
    • Sterols. CXII. Sapogenins. XLI. The preparation of Trillin and its conversion to progesterone
    • Marker RE, Krueger J. Sterols. CXII. Sapogenins. XLI. The preparation of Trillin and its conversion to progesterone. J Am Chem Soc. 1940;62:3349-3350.
    • (1940) J Am Chem Soc , vol.62 , pp. 3349-3350
    • Marker, R.E.1    Krueger, J.2
  • 8
    • 0026036209 scopus 로고
    • Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek
    • Sauvaire Y, Ribes G, Baccou JC, Loubatieeres Mariani MM. Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek. Lipids. 1991;26:191-197.
    • (1991) Lipids , vol.26 , pp. 191-197
    • Sauvaire, Y.1    Ribes, G.2    Baccou, J.C.3    Loubatieeres Mariani, M.M.4
  • 9
    • 4043124898 scopus 로고    scopus 로고
    • Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells
    • Raju J, Patlolla JM, Swamy MV, Rao CV. Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells. Cancer Epidemiol Biomarkers Prev. 2004;13:1392-1398.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 1392-1398
    • Raju, J.1    Patlolla, J.M.2    Swamy, M.V.3    Rao, C.V.4
  • 10
    • 67749089270 scopus 로고    scopus 로고
    • N-methylnitrosourea induced breast cancer in rat, the histopathology of the resulting tumours and its drawbacks as a model
    • Perse M, Cerar A, Injac R, Strukel B. N-methylnitrosourea induced breast cancer in rat, the histopathology of the resulting tumours and its drawbacks as a model. Pathol Oncol Res. 2009;15:115-121.
    • (2009) Pathol Oncol Res , vol.15 , pp. 115-121
    • Perse, M.1    Cerar, A.2    Injac, R.3    Strukel, B.4
  • 11
    • 0018384650 scopus 로고
    • Assay of lipid peroxides in animal tissues by thiobarbituric acid reac tion
    • Ohkawa N, Ohishi K, Yagi. Assay of lipid peroxides in animal tissues by thiobarbituric acid reac tion. Anal Biochem. 1979;95:351-358.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, N.1    Ohishi, N.2    Yagi, K.3
  • 12
    • 0016272750 scopus 로고
    • Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S, Marklund G. Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem. 1974;47:469-474.
    • (1974) Eur J Biochem , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 13
    • 0015353270 scopus 로고
    • Colorimetric assay of catalase
    • Sinha AK. Colorimetric assay of catalase. Anal Biochem. 1972;47:389-394.
    • (1972) Anal Biochem , vol.47 , pp. 389-394
    • Sinha, A.K.1
  • 15
    • 0018327389 scopus 로고
    • Levels of glutathione, glutathione reductase and glutathioneS-transferase activities in rat lung and liver
    • Moron MS, Depierre JW, Mannervik B. Levels of glutathione, glutathione reductase and glutathioneS-transferase activities in rat lung and liver. Biochem Biophys Acta. 1979;58:67-68.
    • (1979) Biochem Biophys Acta , vol.58 , pp. 67-68
    • Moron, M.S.1    Depierre, J.W.2    Mannervik, B.3
  • 16
    • 0021288822 scopus 로고
    • Vitamin E analysis methods for animal tissues
    • Desai ID. Vitamin E analysis methods for animal tissues. Meth Enzymol. 1984;105:138-144.
    • (1984) Meth Enzymol , vol.105 , pp. 138-144
    • Desai, I.D.1
  • 17
    • 0018369625 scopus 로고
    • Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids
    • Omaye ST, Turnbull JD, Sauberlich HE. Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. Meth Enzymol. 1971;62:3-11.
    • (1971) Meth Enzymol , vol.62 , pp. 3-11
    • Omaye, S.T.1    Turnbull, J.D.2    Sauberlich, H.E.3
  • 18
    • 0003114341 scopus 로고
    • The dehydrogenases of oxidoreductases
    • (editor), London, Van D. Nostrand Co. Ltd
    • King J (editor). The dehydrogenases of oxidoreductases. In: Practical and clinical enzymology. London: Van D. Nostrand Co. Ltd.; 1965. p. 83-93.
    • (1965) In: Practical and Clinical Enzymology , pp. 83-93
    • King, J.1
  • 19
    • 0002794972 scopus 로고
    • The transferases alanine and aspartate transaminases
    • (editor), London, Van D. Nostrand Co. Ltd
    • King J (editor). The transferases alanine and aspartate transaminases. In: Practical and clinical enzymology. London: Van D. Nostrand Co. Ltd.; 1965. p. 121-138.
    • (1965) In: Practical and Clinical Enzymology , pp. 121-138
    • King, J.1
  • 20
    • 0015401042 scopus 로고
    • Hormonal control in vitro of plasma membrane bound ATPase of rat liver
    • Luly P, Tria E. Hormonal control in vitro of plasma membrane bound ATPase of rat liver. Biochem Biophys Acta. 1972;282:447-452.
    • (1972) Biochem Biophys Acta , vol.282 , pp. 447-452
    • Luly, P.1    Tria, E.2
  • 22
    • 84871343759 scopus 로고    scopus 로고
    • Hesperidin normalizes lipid peroxidation and membrane bound marker enzymes in 7,12-dimethylbenz(a)anthracene induced breast cancer rats
    • Nandakumar N, Jayaprakesh R, Rengarajan T, Ramesh V, Balasubramanian MP. Hesperidin normalizes lipid peroxidation and membrane bound marker enzymes in 7,12-dimethylbenz(a)anthracene induced breast cancer rats. Biomed Prev Nutr. 2011;1:12-120.
    • (2011) Biomed Prev Nutr , vol.1 , pp. 12-120
    • Nandakumar, N.1    Jayaprakesh, R.2    Rengarajan, T.3    Ramesh, V.4    Balasubramanian, M.P.5
  • 24
    • 0030881274 scopus 로고    scopus 로고
    • The clinical evaluation of cancer prevention agents
    • Goodman GE. The clinical evaluation of cancer prevention agents. Proc Soc Exp Biol Med. 1997;216:253-259.
    • (1997) Proc Soc Exp Biol Med , vol.216 , pp. 253-259
    • Goodman, G.E.1
  • 25
    • 14944365657 scopus 로고    scopus 로고
    • Efficacy of Terminalia arjuna (Roxb.) on Nnitrosodiethylamine induced hepatocellular carcinoma in rats
    • Sivalokanathan S, Ilayaraja M, Balasubramanian MP. Efficacy of Terminalia arjuna (Roxb.) on Nnitrosodiethylamine induced hepatocellular carcinoma in rats. J Exp Biol. 2005;43:264-267.
    • (2005) J Exp Biol , vol.43 , pp. 264-267
    • Sivalokanathan, S.1    Ilayaraja, M.2    Balasubramanian, M.P.3
  • 26
    • 0035850836 scopus 로고    scopus 로고
    • A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells
    • Moalic S, Liagre B, Corbiere C, Bianchi A, Dauca M, Bordji K, Beneytout JL. A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells. FEBS Lett. 2001;506:225-230.
    • (2001) FEBS Lett , vol.506 , pp. 225-230
    • Moalic, S.1    Liagre, B.2    Corbiere, C.3    Bianchi, A.4    Dauca, M.5    Bordji, K.6    Beneytout, J.L.7
  • 27
    • 4444273792 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 prevents DNA damage and restores antioxidant enzymes in rat hepatocarcinogenesis induced by diethylnitrosamine and promoted by phenobarbital
    • Banakar MC, Paramasivam SK, Chattopadhyay MB, Datta S, Thyagarajan E. 1,25-Dihydroxyvitamin D3 prevents DNA damage and restores antioxidant enzymes in rat hepatocarcinogenesis induced by diethylnitrosamine and promoted by phenobarbital. World J Gastreoenterol. 2004;10:1268-1275.
    • (2004) World J Gastreoenterol , vol.10 , pp. 1268-1275
    • Banakar, M.C.1    Paramasivam, S.K.2    Chattopadhyay, M.B.3    Datta, S.4    Thyagarajan, E.5
  • 28
    • 0006198863 scopus 로고    scopus 로고
    • Biomarkers of free radical damage: Applications in experimental animals and in humans
    • Zwart LLD, Meeerman JN, Commandeur JM. Biomarkers of free radical damage: applications in experimental animals and in humans. Free Rad Biol Med. 1999;26:202-226.
    • (1999) Free Rad Biol Med , vol.26 , pp. 202-226
    • Zwart, L.L.D.1    Meeerman, J.N.2    Commandeur, J.M.3
  • 29
    • 83455210585 scopus 로고    scopus 로고
    • Hesperidin protects renal and hepatic tissues against free radical mediated oxidative stress during DMBA induced experimental breast cancer
    • Nandakumar N, Balasubramanian MP. Hesperidin protects renal and hepatic tissues against free radical mediated oxidative stress during DMBA induced experimental breast cancer. J Environ Pathol Toxicol Oncol. 2011;30:1-17.
    • (2011) J Environ Pathol Toxicol Oncol , vol.30 , pp. 1-17
    • Nandakumar, N.1    Balasubramanian, M.P.2
  • 30
    • 34250799689 scopus 로고    scopus 로고
    • Protective effect of Operculina turpethum against 7,12-dimethyl benz(a)anthracene induced oxidative stress with reference to breast cancer in experimental rats
    • Anbuselvam C, Vijayavel K, Balasubramanian MP. Protective effect of Operculina turpethum against 7,12-dimethyl benz(a)anthracene induced oxidative stress with reference to breast cancer in experimental rats. Chem Biol Interact. 2007;168:229-236.
    • (2007) Chem Biol Interact , vol.168 , pp. 229-236
    • Anbuselvam, C.1    Vijayavel, K.2    Balasubramanian, M.P.3
  • 31
    • 0028256239 scopus 로고
    • Prospective investigation of tumor markers and risk assessment in early cancer screening
    • Kobayashi T., Kawakubo T. Prospective investigation of tumor markers and risk assessment in early cancer screening. Cancer. 1994;73:1946-1953.
    • (1994) Cancer , vol.73 , pp. 1946-1953
    • Kobayashi, T.1    Kawakubo, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.