메뉴 건너뛰기




Volumn 15, Issue 1, 2009, Pages 115-121

N-methylnitrosourea induced breast cancer in rat, the histopathology of the resulting tumours and its drawbacks as a model

Author keywords

Animal model; Breast cancer; Histopathology; N methylnitrosourea; Rats

Indexed keywords

METHYLNITROSOUREA;

EID: 67749089270     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12253-008-9117-x     Document Type: Article
Times cited : (28)

References (27)
  • 2
    • 0029991480 scopus 로고    scopus 로고
    • Animal models of breast cancer: Their diversity and role in biomedical research
    • R Clarke 1996 Animal models of breast cancer: their diversity and role in biomedical research Breast Cancer Res Treat 39 1 6
    • (1996) Breast Cancer Res Treat , vol.39 , pp. 1-6
    • Clarke, R.1
  • 3
    • 0029931781 scopus 로고    scopus 로고
    • Experimentally induced mammary tumors in rats
    • J Russo IH Russo 1996 Experimentally induced mammary tumors in rats Breast Cancer Res Treat 39 7 20
    • (1996) Breast Cancer Res Treat , vol.39 , pp. 7-20
    • Russo, J.1    Russo, I.H.2
  • 4
    • 0019430425 scopus 로고
    • Lifetime dose-response relationships for mammary tumor induction by a single administration of N-methyl-N-nitrosourea
    • DL McCormick CB Adamowski A Fiks 1981 Lifetime dose-response relationships for mammary tumor induction by a single administration of N-methyl-N-nitrosourea Cancer Res 41 1690 1694
    • (1981) Cancer Res , vol.41 , pp. 1690-1694
    • McCormick, D.L.1    Adamowski, C.B.2    Fiks, A.3
  • 5
    • 0022476853 scopus 로고
    • Genetic control of resistance to chemically induced mammary adenocarcinogenesis in the rat
    • JT Isaacs 1986 Genetic control of resistance to chemically induced mammary adenocarcinogenesis in the rat Cancer Res 46 3958 3963
    • (1986) Cancer Res , vol.46 , pp. 3958-3963
    • Isaacs, J.T.1
  • 6
    • 0025986723 scopus 로고
    • Dose-responsive induction of mammary gland carcinomas by the intraperitoneal injection of 1-methyl-1-nitrosourea
    • HJ Thompson H Adlakha 1991 Dose-responsive induction of mammary gland carcinomas by the intraperitoneal injection of 1-methyl-1-nitrosourea Cancer Res 51 3411 3415
    • (1991) Cancer Res , vol.51 , pp. 3411-3415
    • Thompson, H.J.1    Adlakha, H.2
  • 7
    • 0033840864 scopus 로고    scopus 로고
    • Histopathology of mammary tumours in female rats treated with 1-methyl-1-nitrosourea
    • J Liska S Galbavy D Macejova 2000 Histopathology of mammary tumours in female rats treated with 1-methyl-1-nitrosourea Endocr Regul 34 91 96
    • (2000) Endocr Regul , vol.34 , pp. 91-96
    • Liska, J.1    Galbavy, S.2    MacEjova, D.3
  • 8
    • 0026770144 scopus 로고
    • Effect of carcinogen dose and age at administration on induction of mammary carcinogenesis by 1-methyl-1-nitrosourea
    • HJ Thompson H Adlakha M Singh 1992 Effect of carcinogen dose and age at administration on induction of mammary carcinogenesis by 1-methyl-1-nitrosourea Carcinogenesis 13 1535 1539
    • (1992) Carcinogenesis , vol.13 , pp. 1535-1539
    • Thompson, H.J.1    Adlakha, H.2    Singh, M.3
  • 9
    • 0028785824 scopus 로고
    • Rapid induction of mammary intraductal proliferations, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea
    • HJ Thompson JN McGinley K Rothhammer 1995 Rapid induction of mammary intraductal proliferations, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea Carcinogenesis 16 2407 2411
    • (1995) Carcinogenesis , vol.16 , pp. 2407-2411
    • Thompson, H.J.1    McGinley, J.N.2    Rothhammer, K.3
  • 11
    • 24944496956 scopus 로고    scopus 로고
    • Gene expression profiling of NMU-induced rat mammary tumors: Cross species comparison with human breast cancer
    • MM Chan X Lu FM Merchant 2005 Gene expression profiling of NMU-induced rat mammary tumors: cross species comparison with human breast cancer Carcinogenesis 26 1343 1353
    • (2005) Carcinogenesis , vol.26 , pp. 1343-1353
    • Chan, M.M.1    Lu, X.2    Merchant, F.M.3
  • 12
    • 0842347429 scopus 로고    scopus 로고
    • Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma
    • AF Badawi MB Eldeen Y Liu 2004 Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma Cancer Res 64 1181 1189
    • (2004) Cancer Res , vol.64 , pp. 1181-1189
    • Badawi, A.F.1    Eldeen, M.B.2    Liu, Y.3
  • 13
    • 0345303976 scopus 로고    scopus 로고
    • Chemoprevention of mammary carcinogenesis in female rats by rofecoxib
    • P Kubatka I Ahlers E Ahlersova 2003 Chemoprevention of mammary carcinogenesis in female rats by rofecoxib Cancer Lett 202 131 136
    • (2003) Cancer Lett , vol.202 , pp. 131-136
    • Kubatka, P.1    Ahlers, I.2    Ahlersova, E.3
  • 14
    • 0034043183 scopus 로고    scopus 로고
    • Experimental basis for the prevention of breast cancer
    • RG Mehta 2000 Experimental basis for the prevention of breast cancer Eur J Cancer 36 1275 1282
    • (2000) Eur J Cancer , vol.36 , pp. 1275-1282
    • Mehta, R.G.1
  • 15
    • 30844439305 scopus 로고    scopus 로고
    • Modulation of N-methyl-N-nitrosourea induced mammary tumors in Sprague-Dawley rats by combination of lysine, proline, arginine, ascorbic acid and green tea extract
    • MW Roomi NW Roomi V Ivanov 2005 Modulation of N-methyl-N-nitrosourea induced mammary tumors in Sprague-Dawley rats by combination of lysine, proline, arginine, ascorbic acid and green tea extract Breast Cancer Res 7 R291 R295
    • (2005) Breast Cancer Res , vol.7
    • Roomi, M.W.1    Roomi, N.W.2    Ivanov, V.3
  • 16
    • 0028100108 scopus 로고
    • Induction of mammary tumors in rat by intraperitoneal injection of NMU: Histopathology and estral cycle influence
    • ES Rivera N Andrade G Martin 1994 Induction of mammary tumors in rat by intraperitoneal injection of NMU: histopathology and estral cycle influence Cancer Lett 86 223 228
    • (1994) Cancer Lett , vol.86 , pp. 223-228
    • Rivera, E.S.1    Andrade, N.2    Martin, G.3
  • 18
    • 0030727861 scopus 로고    scopus 로고
    • Seasonal influence on 7, 12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in Sprague-Dawley rats under controlled laboratory conditions
    • W Loscher M Mevissen B Haussler 1997 Seasonal influence on 7, 12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in Sprague-Dawley rats under controlled laboratory conditions Pharmacol Toxicol 81 265 270
    • (1997) Pharmacol Toxicol , vol.81 , pp. 265-270
    • Loscher, W.1    Mevissen, M.2    Haussler, B.3
  • 19
    • 2442603669 scopus 로고    scopus 로고
    • Seasonal molecular timekeeping within the rat circadian clock
    • A Sumova Z Bendova M Sladek 2004 Seasonal molecular timekeeping within the rat circadian clock Physiol Res 53 Suppl 1 S167 S176
    • (2004) Physiol Res 53 Suppl , vol.1
    • Sumova, A.1    Bendova, Z.2    Sladek, M.3
  • 20
    • 0038237060 scopus 로고    scopus 로고
    • Long term inhibition by estradiol or progesterone of melatonin secretion after administration of a mammary carcinogen, the dimethyl benz(a)anthracene, in Sprague-Dawley female rat; Inhibitory effect of Melatonin on mammary carcinogenesis
    • MB De Jonage-Canonico V Lenoir A Martin 2003 Long term inhibition by estradiol or progesterone of melatonin secretion after administration of a mammary carcinogen, the dimethyl benz(a)anthracene, in Sprague-Dawley female rat; inhibitory effect of Melatonin on mammary carcinogenesis Breast Cancer Res Treat 79 365 377
    • (2003) Breast Cancer Res Treat , vol.79 , pp. 365-377
    • De Jonage-Canonico, M.B.1    Lenoir, V.2    Martin, A.3
  • 21
    • 0008349853 scopus 로고
    • Grundlagenforschung zur Ätiologie des Karzinoms
    • F Halberg 1964 Grundlagenforschung zur Ätiologie des Karzinoms Ärztl Fortb 2 67 77
    • (1964) Ärztl Fortb , vol.2 , pp. 67-77
    • Halberg, F.1
  • 22
    • 0036977891 scopus 로고    scopus 로고
    • Variability of mammary carcinogenesis induction in female Sprague-Dawley and Wistar:Han rats: The effect of season and age
    • P Kubatka E Ahlersova I Ahlers 2002 Variability of mammary carcinogenesis induction in female Sprague-Dawley and Wistar:Han rats: the effect of season and age Physiol Res 51 633 640
    • (2002) Physiol Res , vol.51 , pp. 633-640
    • Kubatka, P.1    Ahlersova, E.2    Ahlers, I.3
  • 23
    • 0031594617 scopus 로고    scopus 로고
    • Pathogenic characterization of 1-methyl-1-nitrosourea-induced mammary carcinomas in the rat
    • J Lu C Jiang T Mitrenga 1998 Pathogenic characterization of 1-methyl-1-nitrosourea-induced mammary carcinomas in the rat Carcinogenesis 19 223 227
    • (1998) Carcinogenesis , vol.19 , pp. 223-227
    • Lu, J.1    Jiang, C.2    Mitrenga, T.3
  • 24
    • 0019778243 scopus 로고
    • Morphology of neoplastic lesions in the clitoral and prepucial gland of the F 334 rat
    • G Reznik JM Ward 1981 Morphology of neoplastic lesions in the clitoral and prepucial gland of the F334 rat J Cancer Res Clin Oncol 101 249 263 (Pubitemid 12239970)
    • (1981) Journal of Cancer Research and Clinical Oncology , vol.101 , Issue.3 , pp. 249-263
    • Reznik, G.1    Ward, J.M.2
  • 25
    • 77957180336 scopus 로고
    • Toxicity and carcinogenicity of 2, 3-dibromo-1-propanol in F344/N rats and B6C3F1 mice
    • SL Eustis JK Haseman WF Mackenzie 1995 Toxicity and carcinogenicity of 2, 3-dibromo-1-propanol in F344/N rats and B6C3F1 mice Fundam Appl Toxicol 26 41 50
    • (1995) Fundam Appl Toxicol , vol.26 , pp. 41-50
    • Eustis, S.L.1    Haseman, J.K.2    MacKenzie, W.F.3
  • 26
    • 0028211311 scopus 로고
    • Inhibition of mammary tumours by pretreatment with 17 beta-estradiol in F344 rats induced with N-methyl-N-nitrosourea
    • O Ito T Okamoto N Fujimoto 1994 Inhibition of mammary tumours by pretreatment with 17 beta-estradiol in F344 rats induced with N-methyl-N-nitrosourea Jpn J Cancer Res 85 279 283
    • (1994) Jpn J Cancer Res , vol.85 , pp. 279-283
    • Ito, O.1    Okamoto, T.2    Fujimoto, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.