HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment

Journal of Neuro-Oncology

Volumn 110, Issue 3, 2012, Pages 335-348

  Milde, Till ^a,b   Lodrini, Marco ^a   Savelyeva, Larissa ^a   Korshunov, Andrey ^a,b   Kool, Marcel ^a   Brueckner, Lena M ^a   Antunes, André S L M ^a,c   Oehme, Ina ^a   Pekrun, Arnulf ^d   Pfister, Stefan M ^a,b   Kulozik, Andreas E ^b   Witt, Olaf ^a,b   Deubzer, Hedwig E ^a,b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d Prof Hess Children's Hospital   (Germany)

Author keywords

Group 3; HC toxin; Irradiation; Medulloblastoma; MYC; Panobinostat; Vorinostat

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; GLIAL FIBRILLARY ACIDIC PROTEIN; HISTONE DEACETYLASE INHIBITOR; KI 67 ANTIGEN; METHOTREXATE; PANOBINOSTAT; PROTEIN P53; VINCRISTINE; VORINOSTAT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER PROGNOSIS; CELL DEATH; CELL STRUCTURE; CLINICAL FEATURE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HYPHOMYCETES; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; ISOCHROMOSOME; MEDULLOBLASTOMA; METASTASIS; NUCLEOTIDE SEQUENCE; ONCOLOGY; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL PROLIFERATION; CEREBELLAR NEOPLASMS; CHILD, PRESCHOOL; COMPARATIVE GENOMIC HYBRIDIZATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; HISTONE DEACETYLASE INHIBITORS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MAGNETIC RESONANCE IMAGING; MALE; MEDULLOBLASTOMA; MICE; MICE, SCID; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 84871275799     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-012-0978-1     Document Type: Article

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