The effects of testosterone on the expression of inflammatory factors in 3T3-L1 adipocytes and its mechanism

National Medical Journal of China

Volumn 89, Issue 21, 2009, Pages 1493-1497

  Su, Chun Lin ^a   Huang, Hai Yan ^b   Shen, Zong Qi ^a   Lin, Jin Fang ^a  

^a FUDAN UNIVERSITY   (China)

^b NONE

Author keywords

Adipocytes; Inflammation factors; Testosterone

Indexed keywords

CCL2 PROTEIN, MOUSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TESTOSTERONE;

ADIPOCYTE; ANIMAL; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN 3T3; DRUG EFFECT; METABOLISM; MOUSE;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; CHEMOKINE CCL2; INTERLEUKIN-6; MICE; NF-KAPPA B; TESTOSTERONE;

EID: 84871261428     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0376-2491.2009.21.016     Document Type: Article

References (10)

1. 2007, 15: 35-37.
2. Escobar-Morreale HF, Botella-Carretero JI, Villuendas, et al. Serum interlukin-18 concentrations are increased in the polycystic ovary syndrome: relationship to insulin resistance and the obesity. J Clin Endocrinol Metab, 2004, 89: 806-811.
3. Benson S, Janssen OE, Hahn S, et al. Obesity, depression, and chronic low-grade inflammation in women with polycystic ovary syndrome. Brain Behav Immun, 2008, 22: 177-184.
4. Hotamisligil GS. Inflammation and metabolic disorders. Nature, 2006, 444: 860-867.
5. Leclerc V, Reichhart J M. The immune response of drosophila melanogaster. Immunol, 2004, 198: 59-71.
6. Kelly C, Lyall H, Petrie JR, et al. Low grade chronic inflammation in women with polycystic ovarian syndrome. J Clin Endocrinol Metab, 2001, 86: 2453-2455.
7. Sayin NC, Gucer F, Balkanli-Kaplan P, et al. Elevated serum TNF-alpha levels in normal-weight women with polycystic ovaries or the polycystic ovary syndrome. J Reprod Med, 2003, 48: 165-170.
8. Kanda H, Tateya S, Tamori Y, et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest, 2006, 116: 1494-1505.
9. Lessard L, Saad F, Le Page C, et al. NF-kappaB processing and p52 nuclear accumulation after androgenic stimulation of LNCaP prostate cancer cells. Cell Signal, 2007, 19: 1093-1100.
10. 2008, 88: 1488-1492.