Parasites and cancers: Parasite antigens as possible targets for cancer immunotherapy

Future Oncology

Volumn 8, Issue 12, 2012, Pages 1529-1535

  Darani, Hossein Yousofi ^a   Yousefi, Morteza ^b  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

cancer; common antigen; immunotherapy; parasite

Indexed keywords

MUCIN; PARASITE ANTIGEN; SIALYL TN ANTIGEN; TF ANTIGEN; TK ANTIGEN; TN ANTIGEN; TOLL LIKE RECEPTOR; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

ACANTHAMOEBA CASTELLANII; ANTIBODY BLOOD LEVEL; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CAUSE OF DEATH; CORRELATION ANALYSIS; DRUG TARGETING; EXPERIMENTAL MODEL; HUMAN; NEOPLASM; NONHUMAN; OVERALL SURVIVAL; PARASITOSIS; PLASMODIUM YOELII; PRIORITY JOURNAL; REVIEW; TOXOCARA CANIS; TOXOPLASMA GONDII; TRYPANOSOMA CRUZI;

ANIMALS; ANTIGENS, NEOPLASM; ANTIGENS, PROTOZOAN; HUMANS; IMMUNOTHERAPY; NEOPLASMS; PARASITES; PROTOZOAN INFECTIONS; TOXOPLASMA; TRYPANOSOMA CRUZI;

EID: 84871226481     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.12.155     Document Type: Review

References (66)

1. Akgül H, Tez M, Ünal AE, Ke kek M, Sayek I, Özçelik T. Echinococcus against cancer: Why not? Cancer 98(9), 1999-2000 (2003
2. Plumelle Y, Gonin C, Edouard A et al. Effect of Strongyloides stercoralis infection and eosinophilia on age at onset and prognosis of adult T-cell leukemia. Am. J. Clin. Pathol. 107(1), 81-87 (1997
3. Chen L, He Z, Qin L et al. Antitumor effect of malaria parasite infection in a murine Lewis lung cancer model through induction of innate and adaptive immunity. Plos One 6(9), e24407 (2011
4. Kallinikova VD, Borisova EN, Pakhorukova LV et al. Immunization against Trypanosoma cruzi and tumor growth in mice. Med. Parazitol. (Mosk.) (4), 9-12 (2006
5. Pidherney MS, Alizadeh H, Stewart GL, McCulley JP, Niederkorn JY. In vitro and in vivo tumoricidal properties of a pathogenic/ free-living amoeba. Cancer Lett. 72(1-2), 91-98 (1993
6. Mel'nikov V, Fierro Velasko F, Dobrovinskaya O. Suppression of growth and metastasizing of T-cell lymphoma in mice infected with American trypanosomiasis at different stages of experimental infection. Bull. Exp. Biol. Med. 137(5), 475-478 (2004
7. Darani HY, Shirzad H, Mansoori F, Zabardast N, Mahmoodzadeh M. Effects of Toxoplasma gondii and Toxocara canis antigens on WEHI- 164 fibrosarcoma growth in a mouse model. Korean J. Parasitol. 47(2), 175 (2009
8. Kallinikova V, Batmonch Z, Kravtsov E, Karpenko L, Pachorukova L, Ogloblina T. Antibodies against Trypanosoma cruzi accompanying the antitumoral action of lysed epimastigotes in vivo. Moscow Univ. Biol. Sci. Bull. 63(2), 72-76 (2008
9. Cancer mortality among American Indians and Alaska Natives - United States, 1994- 1998. MMWR 52(30), 704-707 (2003
10. Batmonkh Z, Kallinikova VD, Pakhorukova LV, Kravtsov EG, Karpenko LP, Dalin MV. In vivo anticancer activity of lysates from Trypanosoma cruzi of different genetic groups. Bull. Exp. Biol. Med. 142(4), 470-473 (2006
11. Kallinikova V, Matekin P, Ogloblina T et al. Anticancer properties of flagellate protozoan Trypanosoma cruzi Chagas, 1909. Biol. Bull. 28(3), 244-255 (2001
12. Kallinikova VD, Batmonkh T, Kosobokova EN et al. Antibodies against Trypanosoma cruzi in intact mice and their oncoprotective effect. Med. Parazitol. (Mosk.) (1), 11-15 (2008
13. Kinnamon KE, Poon BT, Hanson WL, Waits VB. Activity of anticancer compounds against Trypanosoma cruzi-infected mice. Am. J. Trop. Med. Hyg. 58(6), 804-806 (1998
14. Sheklakova L, Kallinikova V, Karpenko L. Genetic heterogeneity of Trypanosoma cruzi and its direct anticancer effect in cultured human tumor cells. Bull. Exp. Biol. Med. 135(1), 89- 92 (2003
15. Zenina A, Kravtsov E, Tsetsegsaikhan B et al. The study of immunological component in antitumor effect of Trypanosoma cruzi. Bull. Exp. Biol. Med. 145(3), 352-354 (2008
16. Choo JD, Lee JS, Kang JS, Lee HS, Yeom JY, Lee YH. Inhibitory effects of Toxoplasma antigen on proliferation and invasion of human glioma cells. J. Korean Neurosurg. 37(2), 129-136 (2005
17. Hibbs JB, Lambert LH, Remington JS. Resistance to murine tumors conferred by chronic infection with intracellular protozoa, Toxoplasma gondii and Besnoitia jellisoni. J. Infect. Dis. 124(6), 587 (1971
18. Kim JO, Jung SS, Kim SY et al. Inhibition of Lewis lung carcinoma growth by Toxoplasma gondii through induction of Th1 immune responses and inhibition of angiogenesis. J. Korean Med. Sci. 22(SUPPL), S38 (2007
19. Miyahara K, Honda U, Tose S et al. Therapeutic effects of Toxoplasma lysate antigen on 20-methylcholanthrene-induced BALB/c mouse tumors. J. Vet. Med. Sci. Jap. 54(1), 7 (1992
20. Miyahara K, Yokoo N, Sakurai H et al. Antitumor activity of Toxoplasma lysate antigen against methylcholanthrene-induced tumor-bearing rats. J. Vet. Med. Sci. Jap. 54(2), 221 (1992
21. Pyo KH, Jung BK, Chai JY, Shin EH. Suppressed CD31 expression in sarcoma-180 tumors after injection with Toxoplasma gondii lysate antigen in BALB/c mice. Korean J. Parasitol. 48(2), 171-174 (2010
22. Suzuki Y, Kobayashi A. Antitumor effect of intralesional injection with formalin-fixed Toxoplasma gondii organisms on Lewis lung carcinoma in Toxoplasma-infected mice. Cancer Lett. 25(3), 247-254 (1985
23. Suzuki Y, Muto M, Kobayashi A. Antitumor effect of formalin-fixed Toxoplasma gondii organisms on EL4 lymphoma in Toxoplasma-infected mice. J. Immunother. 5(4), 288-293 (1986
24. Alizadeh H, Pidherney MS, McCulley JP, Niederkorn JY. Apoptosis as a mechanism of cytolysis of tumor cells by a pathogenic free-living amoeba. Infect. Immun. 62(4), 1298-1303 (1994
25. Zheng X, Uno T, Goto T, Zhang W, Hill JM, Ohashi Y. Pathogenic Acanthamoeba induces apoptosis of human corneal epithelial cells. Jpn J. Ophthalmol. 48(1), 23-29 (2004
26. Baldus SE, Engelmann K, Hanisch FG. MUC1 and the MUCs: A family of human mucins with impact in cancer biology. Crit. Rev. Clin. Lab. Sci. 41(2), 189-231 (2004
27. Thomas PG, Harn DA Jr. Immune biasing by helminth glycans. Cell. Microbiol. 6(1), 13-22 (2004
28. Nyame K, Cummings R, Damian R. Schistosoma mansoni synthesizes glycoproteins containing terminal O-linked N-Acetylglucosamine residues. J. Biol. Chem. 262(17), 7990 (1987
29. Alvarez Errico D, Medeiros A, Míguez M et al. O-glycosylation in Echinococcus granulosus: Identification and characterization of the carcinoma-Associated Tn antigen. Exp. Parasitol. 98(2), 100-109 (2001
30. Ubillos L, Medeiros A, Cancela M et al. Characterization of the carcinoma-Associated Tk antigen in helminth parasites. Exp. Parasitol. 116(2), 129-136 (2007
31. Casaravilla C, Freire T, Malgor R, Medeiros A, Osinaga E, Carmona C. Mucin-type O-glycosylation in helminth parasites from major taxonomic groups: Evidence for widespread distribution of the Tn antigen (GalNAc-Ser/Thr) and identification of UDP-GalNAc: Polypeptide N-Acetylgalactosaminyltransferase activity. J. Parasitol. 89(4), 709-714 (2003
32. Freire T, Casaravilla C, Carmona C, Osinaga E. Mucin-type O-glycosylation in Fasciola hepatica: Characterisation of carcinoma-Associated Tn and sialyl-Tn antigens and evaluation of UDP-GalNAc: Polypeptide N- Acetylgalactosaminyltransferase activity. Int. J. Parasitol. 33(1), 47-56 (2003
33. Thors C, Jansson B, Helin H, Linder E. Thomsen-Friedenreich oncofetal antigen in Schistosoma mansoni: Localization and immunogenicity in experimental mouse infection. Parasitol. Cambridge 132(1), 73 (2006
34. Casaravilla C, Malgor R, Carmona C. Characterization of carbohydrates of adult Echinococcus granulosus by lectin-binding analysis. J. Parasitol. 89(1), 57-61 (2003
35. Anderson RM, May RM. Population biology of infectious diseases: Part I. Nature 280(5721), 361 (1979
36. Pao Chang H. The relationship between primary carcinoma of the liver and infestation with Clonorchis sinensis. J. Pathol. Bacterial. 72(1), 239-246 (1956
37. Thomas JE, Bassett MT, Sigola LB, Taylor P. Relationship between bladder cancer incidence, Schistosoma haematobium infection, and geographical region in Zimbabwe. Trans. Royal Soc. Trop. Med. Hyg. 84(4), 551-553 (1990
38. Abdel-Rahim AY. Parasitic infections and hepatic neoplasia. Digest. Dis. 19(4), 288-291 (2001
39. Zhang ZF, Graham S, Yu SZ et al. Trichomonas vaginalis and cervical cancer: A prospective study in China. Ann. Epidemiol. 5(4), 325-332 (1995
40. Vennervald BJ, Polman K. Helminths and malignancy. Parasite Immunol. 31(11), 686-696 (2009
41. Clegg J, Smithers S, Terry R. Concomitant immunity and host antigens associated with schistosomiasis. Int. J. Parasitol. 1(1), 43-49 (1971
42. Yoosefi H, Vakil N, Shirzad H. A survey about the effect of immune response raised by Leishmania major on fibrosarcoma tumor in mice. J. Arak. Univ. Med. Sci. 10(4), 6 (2007
43. Shirzad H, KS, Soozangar N, Yousefi M, Darani HY. Toxoplasma gondii but not Leishmania major or Trichomonas vaginalis decreases cell proliferation and increases cell death on fibrosarcoma cancer cells in culture medium World J. Vaccine (2012) (In Press
44. Chen K, Huang J, Gong W, Iribarren P, Dunlop NM, Wang JM. Toll-like receptors in inflammation, infection and cancer. Int. Immunopharmacol. 7(10), 1271-1285 (2007
45. Reuben J, Tanner C, Portelance V. Protection of cotton rats against experimental Echinococcus multilocularis infections with BCG cell walls. Infect. Immun. 23(3), 582-586 (1979
46. Kiara SM, Okombo J, Masseno V et al. In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: Emergence of parasites with Ile-164-Leu mutation. Antimicrob. Agents Chemother. 53(9), 3793-3798 (2009
47. Kong G, Kain KC, Crandall I, Langler RF. Novel disulfides as anticancer/antimalarial agents. Sulfur Lett. 26(4), 149-154 (2003
48. McGeary RP, Bennett AJ, Tran QB, Cosgrove KL, Ross BP. Suramin: Clinical uses and structure-Activity relationships. Mini Rev. Med. Chem. 8(13), 1384-1394 (2008
49. Navarro M. Gold complexes as potential anti-parasitic agents. Coordination Chem. Rev. 253(11-12), 1619-1626 (2009
50. Neznanov N, Gorbachev AV, Neznanova L et al. Anti-malaria drug blocks proteotoxic stress response: Anti-cancer implications. Cell Cycle (Georgetown, Tex.) 8(23), 3960 (2009
51. Posner GH, McRiner AJ, Paik IH et al. Anticancer and antimalarial efficacy and safety of artemisinin-derived trioxane dimers in rodents. J. Med. Chem. 47(5), 1299-1301 (2004
52. Stein C, LaRocca R, Thomas R, McAtee N, Myers CE. Suramin: An anticancer drug with a unique mechanism of action. J. Clin. Oncol. 7(4), 499-508 (1989
53. Tavares J, Ouaissi M, Ouaissi A, Cordeiro-da- Silva A. Characterization of the anti- Leishmania effect induced by cisplatin, an anticancer drug. Acta Trop. 103(2), 133-141 (2007
54. Berger B, Fairlamb A. Interactions between immunity and chemotherapy in the treatment of the trypanosomiases and leishmaniases. Parasitol. Cambridge 105, 71-71 (1992
55. Dalton JE, Maroof A, Owens BMJ et al. Inhibition of receptor tyrosine kinases restores immunocompetence and improves immune-dependent chemotherapy against experimental leishmaniasis in mice. J. Clin. Invest. 120(4), 1204-1216 (2010
56. Fallon P, Cooper R, Probert A, Doenhoff M. Immune-dependent chemotherapy of schistosomiasis. Parasitology 105(S1), S41-S48 (1992
57. Gambashidze K, Kalandarishvili K, Khorava P et al. Application of bacterial thermo-And phagelysates for suppression of malignant tumor growth in experimental studies: 2 comparative analysis of anticancer efficacy of thermo-And phagelysates of Ps. aeruginosa and E. coli. Georgian Med. News (207), 50-56 (2012
58. Gambashidze K, Khorava P, Azaladze T et al. Antitumor and adjuvant effects of phagelysates of E. coli in mice with Ehrlich carcinoma. Exp. Oncol. 34(2), 107-111 (2012
59. Akaza H, Hinotsu S, Aso Y, Kakizoe T. Bacillus Calmette-Guérin treatment of existing papillary bladder cancer and carcinoma in situ of the bladder. Four-year results. Cancer 75(2), 552-559 (2006
60. Eilber FR, Morton DL, Holmes EC, Sparks FC, Ramming KP. Adjuvant immunotherapy with BCG in treatment of regional-lymph-node metastases from malignant melanoma. N. Engl. J. Med. 294(5), 237-240 (1976
61. Han RF, Pan JG. Can intravesical Bacillus Calmette-Guérin reduce recurrence in patients with superficial bladder cancer? A meta-Analysis of randomized trials. Urology 67(6), 1216-1223 (2006
62. Atayde VD, Jasiulionis MG, Cortez M, Yoshida N. A recombinant protein based on Trypanosoma cruzi surface molecule gp82 induces apoptotic cell death in melanoma cells. Melanoma Res. 18(3), 172-183 (2008
63. Yousofi Darani H, Soozangar N, Khorami S, Taji F, Yousofi M, Shirzad H. Hydatid cyst protoscolices induce cell death in WEHI-164 fibrosarcoma cells and inhibit the proliferation of baby hamster kidney fibroblasts in vitro. J. Parasitol. Res. 304183 (2012
64. Huby F, Hoste H, Mallet S, Fournel S, Nano J. Effects of the excretory/secretory products of six nematode species, parasites of the digestive tract, on the proliferation of HT29-D4 and HGT-1 cell lines. Epithelial Cell Boil. 4(4), 156-162 (1995
65. Darani H, Curtis R, McNeice C, Price H, Sayers J, Doenhoff M. Schistosoma mansoni: Anomalous immunogenic properties of a 27 kDa larval serine protease associated with protective immunity. Parasitology 115(03), 237-247 (1997
66. Doenhoff M, Curtis RHC, Ngaiza J, Modha J. Proteases in the schistosome life cycle: A paradigm for tumour metastasis. Cancer Metastasis Rev. 9(4), 381-392 (1990