Primary cultures of human urothelial cells for genotoxicity testing

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 71, Issue 13-14, 2008, Pages 930-935

  Flieger, Angelika ^a   Golka, Klaus ^a   Schulze, Harald ^b   Föllmann, Wolfram ^a  

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^b KLINIKUM DORTMUND   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 18; CYTOKERATIN 19; CYTOKERATIN 20; CYTOKERATIN 7; CYTOKERATIN 8;

ADOLESCENT; ADULT; AGED; ARTICLE; BLADDER EPITHELIUM; CELL ADHESION; CELL ISOLATION; CELL PROLIFERATION; CYTOTOXICITY TEST; GENOTOXICITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SCHOOL CHILD; TECHNIQUE; TIME; URETER; UROTHELIUM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHILD; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERMEDIATE FILAMENTS; L-LACTATE DEHYDROGENASE; MALE; MIDDLE AGED; MUTAGENICITY TESTS; TIME FACTORS; URETER; URINARY BLADDER; UROTHELIUM;

SUS;

EID: 47349087022     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390801988939     Document Type: Article

References (33)

1. Belik, R., Föllmann, W., Degen, G. H., Roos, P. H., Blaszkewicz, M., Knopf, H. J., and Golka, K. 2008. Improvements in culturing exfoliated urothelial cells in vitro from human urine. J. Toxicol. Environ. Health A in press.
2. Bergmeyer, H. U. 1983. Methods of enzymatic analysis, 3rd ed., Vols. I-X, eds. H. U. Bergmeyer, J. Bergmeyer, J., and M. Graßl. Weinheim, and Deerfield Beach, FL: Verlag Chemie.
3. Booth, C., Harnden, P., Trejdosiewicz, L. K., Scriven, S., Selby, P. J., and Southgate, J. 1997. Stromal and vascular invasion in an human in vitro bladder cancer model. Lab. Invest. 76:843-857.
4. Cordell, J. L., Falini, B., Erber, W. N., Ghosh, A. K., Abdulaziz, Z., Macdonald, S., Pulford, K. A., Stein, H., and Mason, D. Y. 1984. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase. J. Histochem. Cytochem. 32:219-229.
5. Crallan, R. A., Georgopoulos, N. T., and Southgate, J. 2006. Experimental models of human bladder carcinogenesis. Carcinogenesis 27:374-381.
6. Cross, W. R., Eardley, I., Leese, H. J., and Southgate, J. 2005. A biomimetic tissue from cultured normal human urothelial cells: Analysis of physiological function. Am. J. Physiol. Renal Physiol. 289:F459-F468.
7. Dörrenhaus, A., Flieger, A., Golka, K., Schulze, H., Albrecht, M., Degen, G. H., and Föllmann, W. 2000. Induction of unscheduled DNA synthesis in primary human urothelial cells by the mycotoxin ochratoxin A. Toxicol. Sci. 53:271-277.
8. Flieger, A., Dörrenhaus, A., Golka, K., Schulze, H., and Föllmann, W. 1998. Genotoxic effect of the mycotoxin ochratoxin A in cultured human urothelial cells. Occup. Hyg. 4: 297-307.
9. Föllmann, W., Guhe, C., Weber, S., Birkner, S., and Mähler, S. 2000. Cultured porcine urinary bladder epithelial cells as a screening model for genotoxic effects of aromatic amines: Characterisation and application of the cell culture model. Altern. Lab. Anim. 28:833-854.
10. Franke, W. W., Schiller, D. L., Hatzfeld, M., Magin, T. M., Jocarno, J. L., Mittnacht, S., Schmid, E., Cohlberg, J. A., and Quinlan, R. A. 1984. Cytokeratins: Complex formation, biosynthesis, and interactions with desmosomes. In The transformed phenotype: The Cancer Cell Meeting held at Cold Spring Harbor in Sept. 1983, eds. A. J. Levine, F. G. VandeWoude, W. C. Topp, and J. D. Watson, pp. 177-190. Cold Spring Harbor, NY.
11. Franke, W. W., Schmid, E., Schiller, D. L., Winter, S., Jarasch, E. D., Moll, R., Denk, H., Jackson, B. W., and Illmensee, K. 1982. Differentiation- related patterns of expression of proteins of intermediate size filaments in tissues and cultured cells. In Organization of the cytoplasm, ed. Cold Spring Harbor Laboratory, pp. 431-453. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
12. Gabrielson, E. W., and Harris, C. C. 1985. Use of cultured human tissues and cells in carcinogenesis research. J. Cancer Res. Clin. Oncol. 110:1-10.
13. Greim, H., Arand, M., Autrup, H., Bolt, H. M., Bridges, J., Dybing, E., Glomot, R., Foa, V., and Schulte-Herrmann, R. 2006. Toxicological comments to the discussion about REACH. Arch. Toxicol. 80:121-124.
14. Guhe, C., Degen, G. H., Schuhmacher, U. S., Kiefer, F., and Föllmann, W. 1996. Drug metabolizing enzyme activities in porcine urinary bladder epithelial cell cultures (PUBEC). Arch. Toxicol. 70:599-606.
15. Guhe, C., and Föllmann, W. 1994. Growth and characterization of porcine urinary bladder epithelial cells in vitro. Am. J. Physiol. 266:F298-F308.
16. Hengstler, J. G., Arand, M., Herrero, M. E., and Oesch, F. 1998. Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: Influence on cancer susceptibility. Rec. Res. Cancer Res. 154:47-85.
17. Hijazi, A., Devonec, M., Bouvier, R., and Revillard, P. 1989. Flow cytometry study of cytokeratin 18 expression according to tumor grade and deoxyribonucleic acid content in human bladder tumours. J. Urol. 141:522-526.
18. Holstein, A.F., Sandmann, J., Bresse, l. M., and Davidof, M.S. 1994. Reinvestigation of the transitional epithelium (urothelium) of the human ureter. Ann. Anat. 176:109-117.
19. Huff, J. 1999. Chemicals associated with tumours of the kidney, urinary bladder and thyroid gland in laboratory rodents from 2000 US National Toxicology Program/National Cancer Institute bioassays for carcinogenicity. IARC Sci. Publ. 147:211-225.
20. Jauregui, H.O., Hayner, N.T., Driscoll J.L., Williams-Holland, R., Lipsky, M. H., and Galletti, P.M. 1981. Trypan blue uptake and lactate dehydrogenase in adult hepatocytes, freshly isolated cells, cell suspensions and primary monolayer cultures. In Vitro 17:1100-1110.
21. Kurec, A. S., Baltrucki, L., Mason, D. Y., and Davey, F. R. 1988. Use of the APAAP method in the diagnosis of hematologic disorders. Clin. Lab. Med. 7:223-236.
22. Lebrun, S., Golka, K., Schulze, H., and Föllmann, W. 2006. Glutathione S-transferase polymorphisms and ochratoxin A toxicity in primary human urothelial cells. Toxicology 224:81-90.
23. Mähler, S., Kinne-Saffran, E., Fujisue, H., Kinne, R. K., and Föllmann, W. 1998. Regulation of sorbitol content in cultured porcine urinary bladder epithelial cells. Am. J. Physiol. 274:F342-F347.
24. Messing, E. M. 2002. Urothelial tumors of the urinary tract. In Campbell's urology, 8th ed., eds. P. C. Walsh, A. Retik, E. D. Vaughan, and A. J. Wein, Vol. 4, pp. 2732-2784. Philadelphia: Saunders.
25. Moll, R., Achtstätter, T., Becht, E., Balcarova-Ständer, J., Ittensohn, M., and Franke, W. W. 1988. Cytokeratins in normal and malignant transitional epithelium. Am. J. Pathol. 132:123-144.
26. Moll, R. 1993. Cytokeratins as markers of differentiation. Expression profiles in epithelia and epithelial tumors Veröff. Pathol. 142:1-197 (in German).
27. Moll, R. 1994. Cytokeratins in the histological diagnosis of malignant tumors. Int. J. Biol. Markers 9:63-69.
28. Raghavan, D., Debruyne, F., Herr, H., Jocham, D., Kakizoe, T., Okajima, E., Sandberg, A., and Tannock, I. 1986. Experimental models of bladder cancer: A critical review. Prog. Clin. Biol. Res. 221:171-208.
29. Ramaekers, F., Huysmans, A., Moesker, O., Schaart, G., Herman, C., and Vooijs, P. 1985. Cytokeratin expression during neoplastic progression of human transitional cell carcinomas as detected by a monoclonal and polyclonal antibody. Lab. Invest. 52:31-38.
30. Reedy, E. A., Heatfield, B. M., Trump, B. F., and Resau, J. H. 1990a. Correlation of cytokeratin patterns with histopathology during neoplastic progression in the rat urinary bladder. Pathobiology 58:15-27.
31. Reedy, E. A., Colombo-Burke, K. L., and Resau, J. H. 1990b. Discrimination of cell types in primary transitional cell carcinoma by monoclonal anti-cytokeratin antibodies. Pathobiology 58:304-311.
32. Southgate, J., Varley, C. L., Garthwaite, M. A., Hinley, J., Marsh, F., Stahlschmidt, J., Trejdosiewicz, L. K., and Eardley, I. 2007. Differentiation potential of urothelium from patients with benign bladder dysfunction. Br. J. Urol. Int. 99:1506-1516.
33. Wilbourn, J. D., Partensky, C., and Rice, J. M. 1999. Agents that induce epithelial neoplasms of the urinary bladder, renal cortex and thyroid follicular lining in experimental animals and humans: Summary of data from IARC monographs volumes 1-69. IARC Sci. Publ. 147:191-209.