Taxol-stabilized microtubules promote the formation of filaments from unmodified full-length Tau in vitro

Molecular Biology of the Cell

Volumn 23, Issue 24, 2012, Pages 4796-4806

  Duan, Aranda R ^a   Goodson, Holly V ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PACLITAXEL; TAU PROTEIN; TUBULIN;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; MICROTUBULE; NEUROFIBRILLARY TANGLE; NEUROFILAMENT; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SEDIMENTATION;

ALZHEIMER DISEASE; BINDING, COMPETITIVE; BLOTTING, WESTERN; HEPARIN; HUMANS; KINETICS; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; MICROTUBULES; NEUROFIBRILLARY TANGLES; PACLITAXEL; PROTEIN BINDING; TAU PROTEINS; TUBULIN MODULATORS;

EID: 84871199132     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-05-0374     Document Type: Article

References (40)

1. Ackmann M, Wiech H, Mandelkow E (2000). Nonsaturable binding indicates clustering of tau on the microtubule surface in a paired helical filament-like conformation. J Biol Chem 275, 30335-30343.
2. Al-Bassam J, Ozer RS, Safer D, Halpain S, Milligan RA (2002). MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments. J Cell Biol 157, 1187-1196.
3. 262 combined causes neurodegeneration. J Biol Chem 285, 30851-30860.
4. Amos LA (2000). Focusing-in on microtubules. Curr Opin Struct Biol 10, 236-241.
5. Glued is required for the formation and maintenance of a radial microtubule array anchored at the centrosome. Mol Biol Cell 13, 186A.
6. Barghorn S, Mandelkow E (2002). Toward a unified scheme for the aggregation of TAU into Alzheimer paired helical filaments. Biochemistry 41, 14885-14896.
7. Bunker JM, Wilson L, Jordan MA, Feinstein SC (2004). Modulation of microtubule dynamics by tau in living cells: implications for development and neurodegeneration. Mol Biol Cell 15, 2720-2728.
8. Choi MC et al. (2009). Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: a synchrotron x-ray scattering study. Biophys J 97, 519-527.
9. Crowther RA (1991). Straight and paired helical filaments in Alzheimer disease have a common structural unit. Proc Natl Acad Sci USA 88, 2288-2292.
10. Desai A, Mitchison TJ (1997). Microtubule polymerization dynamics. Annu Rev Cell Dev Biol 13, 83-117.
11. Fauquant C, Redeker V, Landrieu I, Wieruszeski JM, Verdegem D, Laprevote O, Lippens G, Gigant B, Knossow M (2011). Systematic identification of tubulin-interacting fragments of the microtubule-associated protein Tau leads to a highly efficient promoter of microtubule assembly. J Biol Chem 286, 33358-33368.
12. Friedhoff P, Schneider A, Mandelkow EM, Mandelkow E (1998). Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution. Biochemistry 37, 10223-10230.
13. Goedert M, Jakes R, Crowther RA (1999). Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments. FEBS Lett 450, 306-311.
14. Goedert M, Spillantini MG, Cairns NJ, Crowther RA (1992). Tau proteins of Alzheimer paired helical filaments - abnormal phosphorylation of all six brain isoforms. Neuron 8, 159-168.
15. Goode BL, Feinstein SC (1994). Identification of a novel microtubule-binding and assembly domain in the developmentally-regulated inter-repeat region of tau. J Cell Biol 124, 769-782.
16. Hiraoka S, Yao TM, Minoura K, Tomoo K, Sumida M, Taniguchi T, Ishida T (2004). Conformational transition state is responsible for assembly of microtubule-binding domain of tau protein. Biochem Biophys Res Commun 315, 659-663.
17. Hirokawa N, Shiomura Y, Okabe S (1988). Tau proteins: the molecular structure and mode of binding on microtubules. J Cell Biol 107, 1449-1459.
18. Howard J, Hyman AA (2003). Dynamics and mechanics of the microtubule plus end. Nature 422, 753-758.
19. Jeganathan S, von Bergen M, Mandelkow EM, Mandelkow E (2008). The natively unfolded character of Tau and its aggregation to Alzheimer-like paired helical filaments. Biochemistry 47, 10526-10539.
20. Kar S, Fan J, Smith MJ, Goedert M, Amos LA (2003). Repeat motifs of tau bind to the insides of microtubules in the absence of taxol. EMBO J 22, 70-77.
21. Kempf M, Clement A, Faissner A, Lee G, Brandt R (1996). Tau binds to the distal axon early in development of polarity in a microtubule- and microfilament-dependent manner. J Neurosci 16, 5583-5592.
22. Makrides V, Massie MR, Feinstein SC, Lew J (2004). Evidence for two distinct binding sites for tau on microtubules. Proc Natl Acad Sci USA 101, 6746-6751.
23. Makrides V, Shen TE, Bhatia R, Smith BL, Thimm J, Lal R, Feinstein SC (2003). Microtubule-dependent oligomerization of tau - implications for physiological tau function and tauopathies. J Biol Chem 278, 33298-33304.
24. Mitchison T, Kirschner M (1984). Dynamic instability of microtubule growth. Nature 312, 237-242.
25. Mizushima F, Minoura K, Tomoo K, Sumida A, Taniguchi T, Ishida T (2007). Marked difference between self-aggregations of first and fourth repeat peptides on tau microtubule-binding domain in acidic solution. J Biochem 142, 49-54.
26. Panda D, Goode BL, Feinstein SC, Wilson L (1995). Kinetic stabilization of microtubule dynamics at steady-state by tau and microtubule-binding domains of tau. Biochemistry 34, 11117-11127.
27. Paudel HK, Li W (1999). Heparin-induced conformational change in microtubule-associated protein tau as detected by chemical cross-linking and phosphopeptide mapping. J Biol Chem 274, 8029-8038.
28. Philip JT, Pence CH, Goodson HV (2012). MTBindingSim: simulate protein binding to microtubules. Bioinformatics 28, 441-443.
29. Ramachandran G, Udgaonkar JB (2011). Understanding the kinetic roles of the inducer heparin and of rod-like protofibrils during amyloid fibril formation by Tau protein. J Biol Chem 286, 38948-38959.
30. Schaap IAT, Hoffmann B, Carrasco C, Merkel R, Schmidt CF (2007). Tau protein binding forms a 1 nm thick layer along protofilaments without affecting the radial elasticity of microtubules. J Struct Biol 158, 282-292.
31. Sillen A, Barbier P, Landrieu I, Lefebvre S, Wieruszeski JM, Leroy A, Peyrot V, Lippens G (2007). NMR investigation of the interaction between the neuronal protein Tau and the microtubules. Biochemistry 46, 3055-3064.
32. Slaughter T, Wang J, Black MM (1997). Microtubule transport from the cell body into the axons of growing neurons. J Neurosci 17, 5807-5819.
33. Smith MJ, Crowther RA, Goedert M (2000). The natural osmolyte trimethylamine N-oxide (TMAO) restores the ability of mutant tau to promote microtubule assembly. FEBS Lett 484, 265-270.
34. Sun Q, Gamblin TC (2009). Pseudohyperphosphorylation causing AD-like changes in Tau has significant effects on its polymerization. Biochemistry 48, 6002-6011.
35. Tanaka EM, Kirschner MW (1991). Microtubule behavior in the growth cones of living neurons during axon elongation. J Cell Biol 115, 345-363.
36. Wegmann S, Jung YJ, Chinnathambi S, Mandelkow E-M, Mandelkow E, Muller DJ (2010). Human tau isoforms assemble into ribbon-like fibrils that display polymorphic structure and stability. J Biol Chem 285, 27302-27313.
37. Wegmann S, Scholer J, Bippes CA, Mandelkow E, Muller DJ (2011). Competing interactions stabilize pro- and anti-aggregant conformations of human tau. J Biol Chem 286, 20512-20524.
38. Wille H, Drewes G, Biernat J, Mandelkow E-M, Mandelkow E (1992). Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro. J Cell Biol 118, 573-584.
39. Witte H, Neukirchen D, Bradke F (2008). Microtubule stabilization specifies initial neuronal polarization. J Cell Biol 180, 619-632.
40. Zhu ZQC, Gupta KK, Slabbekoorn AR, Paulson BA, Folker ES, Goodson HV (2009). Interactions between EB1 and microtubules: dramatic effect of affinity tags and evidence for cooperative behavior. J Biol Chem 284, 32651-32661.