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Volumn 23, Issue 1, 2013, Pages 17-24

Hormonal manipulation of benign prostatic hyperplasia

Author keywords

5 alpha reductase inhibitor; benign prostatic hyperplasia; gonadotropin releasing hormone; growth hormone releasing hormone; lower urinary tract symptoms; luteinizing hormone releasing hormone

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; CETRORELIX; DOXAZOSIN; DUTASTERIDE; DUTASTERIDE PLUS TAMSULOSIN; FINASTERIDE; GONADORELIN ANTAGONIST; GROWTH HORMONE RELEASING HORMONE ANTAGONIST; HORMONE ANTAGONIST; PROSTATE SPECIFIC ANTIGEN; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 84871198115     PISSN: 09630643     EISSN: 14736586     Source Type: Journal    
DOI: 10.1097/MOU.0b013e32835abd18     Document Type: Review
Times cited : (16)

References (74)
  • 1
    • 0028366359 scopus 로고
    • Etiology of benign prostatic hyperplasia
    • Isaacs JT. Etiology of benign prostatic hyperplasia. Eur Urol 1994; 25 (Suppl. 1):6-9. (Pubitemid 23355406)
    • (1994) European Urology , vol.25 , Issue.SUPPL. 1 , pp. 6-9
    • Isaacs, J.T.1
  • 2
    • 83055176320 scopus 로고    scopus 로고
    • Alpha-blockers for benign prostatic hyperplasia: The new era
    • Lepor H, Kazzazi A, Djavan B. Alpha-blockers for benign prostatic hyperplasia: The new era. Curr Opin Urol 2012; 22:7-15.
    • (2012) Curr Opin Urol , vol.22 , pp. 7-15
    • Lepor, H.1    Kazzazi, A.2    Djavan, B.3
  • 3
    • 84857417474 scopus 로고    scopus 로고
    • Dutasteride for the treatment of prostaterelated conditions
    • Slater S, Dumas C, Bubley G. Dutasteride for the treatment of prostaterelated conditions. Expert Opin Drug Saf 2012; 11:325-330.
    • (2012) Expert Opin Drug Saf , vol.11 , pp. 325-330
    • Slater, S.1    Dumas, C.2    Bubley, G.3
  • 4
    • 84865483412 scopus 로고    scopus 로고
    • Medical treatment of benign prostatic hyperplasia
    • Lepor H. Medical treatment of benign prostatic hyperplasia. Rev Urol 2011; 13:20-33.
    • (2011) Rev Urol , vol.13 , pp. 20-33
    • Lepor, H.1
  • 5
    • 33847239396 scopus 로고    scopus 로고
    • Benign prostatic hyperplasia: An overview
    • Roehrborn CG. Benign prostatic hyperplasia: An overview. Rev Urol 2005; 7 (Suppl. 9):S3YS14.
    • (2005) Rev Urol , vol.7 , Issue.SUPPL. 9
    • Roehrborn, C.G.1
  • 6
    • 0025336895 scopus 로고
    • Clinical and experimental studies of benign prostatic hyperplasia
    • Coffey DS, Walsh PC. Clinical and experimental studies of benign prostatic hyperplasia. Urol Clin North Am 1990; 17:461-475. (Pubitemid 20220190)
    • (1990) Urologic Clinics of North America , vol.17 , Issue.3 , pp. 461-475
    • Coffey, D.S.1    Walsh, P.C.2
  • 7
    • 14844301664 scopus 로고    scopus 로고
    • Benign prostatic hyperplasia: Age-related tissue-remodeling
    • DOI 10.1016/j.exger.2004.12.008
    • Untergasser G, Madersbacher S, Berger P. Benign prostatic hyperplasia: Age-related tissue-remodeling. Exp Gerontol 2005; 40:121-128. (Pubitemid 40343002)
    • (2005) Experimental Gerontology , vol.40 , Issue.3 , pp. 121-128
    • Untergasser, G.1    Madersbacher, S.2    Berger, P.3
  • 8
    • 33947247395 scopus 로고    scopus 로고
    • Is Benign Prostatic Hyperplasia (BPH) an Immune Inflammatory Disease?
    • DOI 10.1016/j.eururo.2006.12.011, PII S030228380601582X
    • Kramer G, Mitteregger D, Marberger M. Is benign prostatic hyperplasia (BPH) an immune inflammatory disease? Eur Urol 2007; 51:1202-1216. (Pubitemid 46436310)
    • (2007) European Urology , vol.51 , Issue.5 , pp. 1202-1216
    • Kramer, G.1    Mitteregger, D.2    Marberger, M.3
  • 9
    • 34548751794 scopus 로고    scopus 로고
    • Prostatic stromal cells derived from benign prostatic hyperplasia specimens possess stem cell like property
    • DOI 10.1002/pros.20599
    • Lin VK, Wang SY, Vazquez DV, et al. Prostatic stromal cells derived from benign prostatic hyperplasia specimens possess stem cell like property. Prostate 2007; 67:1265-1276. (Pubitemid 47435774)
    • (2007) Prostate , vol.67 , Issue.12 , pp. 1265-1276
    • Lin, V.K.1    Wang, S.-Y.2    Vazquez, D.V.3    Xu, C.C.4    Zhang, S.5    Tang, L.6
  • 10
    • 48749119744 scopus 로고    scopus 로고
    • Growth factors in benign prostatic hyperplasia: Basic science implications
    • Lucia MS, Lambert Jr. Growth factors in benign prostatic hyperplasia: Basic science implications. Curr Urol Rep 2008; 9:272-278.
    • (2008) Curr Urol Rep , vol.9 , pp. 272-278
    • Lucia, M.S.1    Lambert, J.R.2
  • 11
    • 0042830775 scopus 로고    scopus 로고
    • Increased growth factor production in a human prostatic stromal cell culture model caused by hypoxia
    • DOI 10.1002/pros.10279
    • Berger AP, Kofler K, Bektic J, et al. Increased growth factor production in a human prostatic stromal cell culture model caused by hypoxia. Prostate 2003; 57:57-65. (Pubitemid 37070150)
    • (2003) Prostate , vol.57 , Issue.1 , pp. 57-65
    • Berger, A.P.1    Kofler, K.2    Bektic, J.3    Rogatsch, H.4    Steiner, H.5    Bartsch, G.6    Klocker, H.7
  • 12
    • 62449153891 scopus 로고    scopus 로고
    • A role for epithelialmesenchymal transition in the etiology of benign prostatic hyperplasia
    • Alonso-Magdalena P, Brossner C, Reiner A, et al. A role for epithelialmesenchymal transition in the etiology of benign prostatic hyperplasia. Proc Natl Acad Sci USA 2009; 106:2859-2863.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 2859-2863
    • Alonso-Magdalena, P.1    Brossner, C.2    Reiner, A.3
  • 13
    • 79952774082 scopus 로고    scopus 로고
    • LHRH antagonist cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia
    • Rick FG, Schally AV, Block NL, et al. LHRH antagonist cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia. Prostate 2011; 71:736-747.
    • (2011) Prostate , vol.71 , pp. 736-747
    • Rick, F.G.1    Schally, A.V.2    Block, N.L.3
  • 14
    • 79952743530 scopus 로고    scopus 로고
    • Antagonists of growth hormonereleasing hormone (GHRH) reduce prostate size in experimental benign prostatic hyperplasia
    • Rick FG, Schally AV, Block NL, et al. Antagonists of growth hormonereleasing hormone (GHRH) reduce prostate size in experimental benign prostatic hyperplasia. Proc Natl Acad Sci USA 2011; 108:3755-3760.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 3755-3760
    • Rick, F.G.1    Schally, A.V.2    Block, N.L.3
  • 15
    • 84858702550 scopus 로고    scopus 로고
    • Combining growth hormone-releasing hormone antagonist with luteinizing hormone-releasing hormone antagonist greatly augments benign prostatic hyperplasia shrinkage
    • Rick FG, Szalontay L, Schally AV, et al. Combining growth hormone-releasing hormone antagonist with luteinizing hormone-releasing hormone antagonist greatly augments benign prostatic hyperplasia shrinkage. J Urol 2012; 187:1498-1504.
    • (2012) J Urol , vol.187 , pp. 1498-1504
    • Rick, F.G.1    Szalontay, L.2    Schally, A.V.3
  • 16
    • 77954398049 scopus 로고    scopus 로고
    • Mechanisms of inhibition of human benign prostatic hyperplasia in vitro by the luteinizing hormonereleasing hormone antagonist cetrorelix
    • Siejka A, Schally AV, Block NL, Barabutis N. Mechanisms of inhibition of human benign prostatic hyperplasia in vitro by the luteinizing hormonereleasing hormone antagonist cetrorelix. BJU Int 2010; 106:1382-1388.
    • (2010) BJU Int , vol.106 , pp. 1382-1388
    • Siejka, A.1    Schally, A.V.2    Block, N.L.3    Barabutis, N.4
  • 17
    • 77953397078 scopus 로고    scopus 로고
    • Antagonists of growth hormonereleasing hormone inhibit the proliferation of human benign prostatic hyperplasia cells
    • Siejka A, Schally AV, Block NL, Barabutis N. Antagonists of growth hormonereleasing hormone inhibit the proliferation of human benign prostatic hyperplasia cells. Prostate 2010; 70:1087-1093.
    • (2010) Prostate , vol.70 , pp. 1087-1093
    • Siejka, A.1    Schally, A.V.2    Block, N.L.3    Barabutis, N.4
  • 18
    • 0027323620 scopus 로고
    • Finasteride: The first 5 alpha-reductase inhibitor
    • discussion 325-329
    • Sudduth SL, Koronkowski MJ. Finasteride: The first 5 alpha-reductase inhibitor. Pharmacotherapy 1993; 13:309-325; discussion 325-329.
    • (1993) Pharmacotherapy , vol.13 , pp. 309-325
    • Sudduth, S.L.1    Koronkowski, M.J.2
  • 19
    • 77957024031 scopus 로고    scopus 로고
    • Combined medical treatment using dutasteride and tamsulosin for lower urinary tract symptoms suggestive of benign prostatic hyperplasia
    • Djavan B, Handl MJ, Dianat S. Combined medical treatment using dutasteride and tamsulosin for lower urinary tract symptoms suggestive of benign prostatic hyperplasia. Expert Opin Pharmacother 2010; 11:2535-2547.
    • (2010) Expert Opin Pharmacother , vol.11 , pp. 2535-2547
    • Djavan, B.1    Handl, M.J.2    Dianat, S.3
  • 21
    • 70449536472 scopus 로고    scopus 로고
    • The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study
    • Roehrborn CG, Siami P, Barkin J, et al. The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study. Eur Urol 2010; 57:123-131.
    • (2010) Eur Urol , vol.57 , pp. 123-131
    • Roehrborn, C.G.1    Siami, P.2    Barkin, J.3
  • 22
    • 85027936953 scopus 로고    scopus 로고
    • The effects of combination therapy with dutasteride plus tamsulosin on clinical outcomes in men with symptomatic BPH: 4-year post hoc analysis of European men in the CombAT study
    • Haillot O, Fraga A, Maciukiewicz P, et al. The effects of combination therapy with dutasteride plus tamsulosin on clinical outcomes in men with symptomatic BPH: 4-year post hoc analysis of European men in the CombAT study. Prostate Cancer Prostatic Dis 2011; 14:302-306.
    • (2011) Prostate Cancer Prostatic Dis , vol.14 , pp. 302-306
    • Haillot, O.1    Fraga, A.2    Maciukiewicz, P.3
  • 23
    • 84859526268 scopus 로고    scopus 로고
    • Quantifying the contribution of symptom improvement to satisfaction of men with moderate to severe benign prostatic hyperplasia: 4-year data from the CombAT trial
    • Roehrborn CG, Wilson TH, Black LK. Quantifying the contribution of symptom improvement to satisfaction of men with moderate to severe benign prostatic hyperplasia: 4-year data from the CombAT trial. J Urol 2012; 187:1732-1738.
    • (2012) J Urol , vol.187 , pp. 1732-1738
    • Roehrborn, C.G.1    Wilson, T.H.2    Black, L.K.3
  • 24
    • 79957696618 scopus 로고    scopus 로고
    • Steroid 5 a-reductase inhibitors targeting BPH and prostate cancer
    • Schmidt LJ, Tindall DJ. Steroid 5 a-reductase inhibitors targeting BPH and prostate cancer. J Steroid Biochem Mol Biol 2011; 125:32-38.
    • (2011) J Steroid Biochem Mol Biol , vol.125 , pp. 32-38
    • Schmidt, L.J.1    Tindall, D.J.2
  • 25
    • 84871226235 scopus 로고    scopus 로고
    • Guidelines on Management of Male Lower Urinary Tract Symptoms (LUTS), incl. Benign Prostatic Obstruction (BPO). In: EAU Guidelines, edition presented at the 27th EAU Annual Congress, Paris 2012. ISBN 978-90-79754-83-0.
    • Oelke M, Bachmann A, Descazeaud A, et al. members of the European Association of Urology (EAU) Guidelines Office. Guidelines on Management of Male Lower Urinary Tract Symptoms (LUTS), incl. Benign Prostatic Obstruction (BPO). In: EAU Guidelines, edition presented at the 27th EAU Annual Congress, Paris 2012. ISBN 978-90-79754-83-0. 2012.
    • (2012) Members of the European Association of Urology (EAU) Guidelines Office
    • Oelke, M.1    Bachmann, A.2    Descazeaud, A.3
  • 26
    • 79953768905 scopus 로고    scopus 로고
    • Update on AUA guideline on the management of benign prostatic hyperplasia
    • McVary KT, Roehrborn CG, Avins AL, et al. Update on AUA guideline on the management of benign prostatic hyperplasia. J Urol 2011; 185:1793-1803.
    • (2011) J Urol , vol.185 , pp. 1793-1803
    • McVary, K.T.1    Roehrborn, C.G.2    Avins, A.L.3
  • 27
    • 33847197555 scopus 로고    scopus 로고
    • A large retrospective analysis of acute urinary retention and prostate-related surgery in BPH patients treated with 5-alpha reductase inhibitors: Dutasteride versus finasteride
    • Issa MM, Runken MC, Grogg AL, Shah MB. A large retrospective analysis of acute urinary retention and prostate-related surgery in BPH patients treated with 5-alpha reductase inhibitors: Dutasteride versus finasteride. Am J Manag Care 2007; 13 (Suppl. 1):S10YS16.
    • (2007) Am J Manag Care , vol.13 , Issue.SUPPL. 1
    • Issa, M.M.1    Runken, M.C.2    Grogg, A.L.3    Shah, M.B.4
  • 28
    • 84862886539 scopus 로고    scopus 로고
    • Finasteride reduces the risk of incident clinical benign prostatic hyperplasia
    • Parsons JK, Schenk JM, Arnold KB, et al. Finasteride reduces the risk of incident clinical benign prostatic hyperplasia. Eur Urol 2012; 62:234-241.
    • (2012) Eur Urol , vol.62 , pp. 234-241
    • Parsons, J.K.1    Schenk, J.M.2    Arnold, K.B.3
  • 29
    • 79960589121 scopus 로고    scopus 로고
    • Comparison of dutasteride and finasteride for treating benign prostatic hyperplasia: The enlarged prostate international comparator study (epics)
    • Nickel JC, Gilling P, Tammela TL, et al. Comparison of dutasteride and finasteride for treating benign prostatic hyperplasia: The Enlarged Prostate International Comparator Study (EPICS). BJU Int 2011; 108:388-394.
    • (2011) BJU Int , vol.108 , pp. 388-394
    • Nickel, J.C.1    Gilling, P.2    Tammela, T.L.3
  • 30
    • 79960589121 scopus 로고    scopus 로고
    • Re: Comparison of dutasteride and finasteride for treating benign prostatic hyperplasia: The enlarged prostate international comparator study (epics)
    • Kaplan SA. Re: Comparison of dutasteride and finasteride for treating benign prostatic hyperplasia: The Enlarged Prostate International Comparator Study (EPICS). BJU Int 2011; 108:388-394.
    • (2011) BJU Int , vol.108 , pp. 388-394
    • Kaplan, S.A.1
  • 31
    • 79955471453 scopus 로고    scopus 로고
    • The effects of dutasteride or tamsulosin alone and in combination on storage and voiding symptoms in men with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). 4-year data from the Combination of Avodart and Tamsulosin (CombAT)
    • Montorsi F, Roehrborn C, Garcia-penit J, et al. The effects of dutasteride or tamsulosin alone and in combination on storage and voiding symptoms in men with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH): 4-year data from the Combination of Avodart and Tamsulosin (CombAT) s. BJU Int 2011; 107:1426-1431.
    • (2011) BJU Int , vol.107 , pp. 1426-1431
    • Montorsi, F.1    Roehrborn, C.2    Garcia-penit, J.3
  • 32
    • 79952584014 scopus 로고    scopus 로고
    • Clinical outcomes after combined therapy with dutasteride plus tamsulosin or either monotherapy in men with benign prostatic hyperplasia (BPH) by baseline characteristics: 4-year results from the randomized, double-blind combination of avodart and tamsulosin
    • Roehrborn CG, Barkin J, Siami P, et al. Clinical outcomes after combined therapy with dutasteride plus tamsulosin or either monotherapy in men with benign prostatic hyperplasia (BPH) by baseline characteristics: 4-year results from the randomized, double-blind combination of avodart and tamsulosin. BJU Int 2011; 107:946-954.
    • (2011) BJU Int , vol.107 , pp. 946-954
    • Roehrborn, C.G.1    Barkin, J.2    Siami, P.3
  • 33
    • 84857355787 scopus 로고    scopus 로고
    • Cost-effectiveness of combination therapy for treatment of benign prostatic hyperplasia: A model based on the findings of the Combination of Avodart and Tamsulosin trial
    • Bjerklund Johansen TE, Baker TM, Black LK. Cost-effectiveness of combination therapy for treatment of benign prostatic hyperplasia: A model based on the findings of the Combination of Avodart and Tamsulosin trial. BJU Int 2012; 109:731-738.
    • (2012) BJU Int , vol.109 , pp. 731-738
    • Bjerklund Johansen, T.E.1    Baker, T.M.2    Black, L.K.3
  • 34
    • 63149140375 scopus 로고    scopus 로고
    • Finasteride monotherapy maintains stable lower urinary tract symptoms in men with benign prostatic hyperplasia following cessation of alpha blockers
    • Nickel JC, Barkin J, Koch C, et al. Finasteride monotherapy maintains stable lower urinary tract symptoms in men with benign prostatic hyperplasia following cessation of alpha blockers. Can Urol Assoc J 2008; 2:16-21.
    • (2008) Can Urol Assoc J , vol.2 , pp. 16-21
    • Nickel, J.C.1    Barkin, J.2    Koch, C.3
  • 35
    • 79751520081 scopus 로고    scopus 로고
    • Androgen replacement therapy contributes to improving lower urinary tract symptoms in patients with hypogonadism and benign prostate hypertrophy: A randomised controlled study
    • Shigehara K, Sugimoto K, Konaka H, et al. Androgen replacement therapy contributes to improving lower urinary tract symptoms in patients with hypogonadism and benign prostate hypertrophy: A randomised controlled study. Aging Male 2011; 14:53-58.
    • (2011) Aging Male , vol.14 , pp. 53-58
    • Shigehara, K.1    Sugimoto, K.2    Konaka, H.3
  • 36
    • 77954409942 scopus 로고    scopus 로고
    • Testosterone therapy in men with androgen deficiency syndromes: An Endocrine Society clinical practice guideline
    • Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in men with androgen deficiency syndromes: An Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2010; 95:2536-2559.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2536-2559
    • Bhasin, S.1    Cunningham, G.R.2    Hayes, F.J.3
  • 37
    • 79958287449 scopus 로고    scopus 로고
    • Dutasteride reduces prostate size and prostate specific antigen in older hypogonadal men with benign prostatic hyperplasia undergoing testosterone replacement therapy
    • Page ST, Hirano L, Gilchriest J, et al. Dutasteride reduces prostate size and prostate specific antigen in older hypogonadal men with benign prostatic hyperplasia undergoing testosterone replacement therapy. J Urol 2011; 186:191-197.
    • (2011) J Urol , vol.186 , pp. 191-197
    • Page, S.T.1    Hirano, L.2    Gilchriest, J.3
  • 39
    • 77950498003 scopus 로고    scopus 로고
    • Effect of dutasteride on the risk of prostate cancer
    • Andriole GL, Bostwick DG, Brawley OW, et al. Effect of dutasteride on the risk of prostate cancer. N Engl J Med 2010; 362:1192-1202.
    • (2010) N Engl J Med , vol.362 , pp. 1192-1202
    • Andriole, G.L.1    Bostwick, D.G.2    Brawley, O.W.3
  • 40
    • 40849135468 scopus 로고    scopus 로고
    • The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer
    • Tindall DJ, Rittmaster RS. The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer. J Urol 2008; 179:1235-1242.
    • (2008) J Urol , vol.179 , pp. 1235-1242
    • Tindall, D.J.1    Rittmaster, R.S.2
  • 41
    • 79955826230 scopus 로고    scopus 로고
    • Finasteride upregulates expression of androgen receptor in hyperplastic prostate and LNCaP cells: Implications for chemoprevention of prostate cancer
    • Hsieh J-T, Chen S-C, Yu H-J, Chang H-C. Finasteride upregulates expression of androgen receptor in hyperplastic prostate and LNCaP cells: Implications for chemoprevention of prostate cancer. Prostate 2011; 71:1115-1121.
    • (2011) Prostate , vol.71 , pp. 1115-1121
    • Hsieh, J.-T.1    Chen, S.-C.2    Yu, H.-J.3    Chang, H.-C.4
  • 42
    • 84859468440 scopus 로고    scopus 로고
    • Usefulness of prostate-specific antigen (PSA) rise as a marker of prostate cancer in men treated with dutasteride: Lessons from the REDUCE study
    • Marberger M, Freedland SJ, Andriole GL, et al. Usefulness of prostate-specific antigen (PSA) rise as a marker of prostate cancer in men treated with dutasteride: Lessons from the REDUCE study. BJU Int 2012; 109:1162-1169.
    • (2012) BJU Int , vol.109 , pp. 1162-1169
    • Marberger, M.1    Freedland, S.J.2    Andriole, G.L.3
  • 43
    • 78650684271 scopus 로고    scopus 로고
    • Effect of dutasteride on prostate biopsy rates and the diagnosis of prostate cancer in men with lower urinary tract symptoms and enlarged prostates in the combination of avodart and tamsulosin trial
    • Roehrborn CG, Andriole GL, Wilson TH, et al. Effect of dutasteride on prostate biopsy rates and the diagnosis of prostate cancer in men with lower urinary tract symptoms and enlarged prostates in the Combination of Avodart and Tamsulosin trial. Eur Urol 2011; 59:244-249.
    • (2011) Eur Urol , vol.59 , pp. 244-249
    • Roehrborn, C.G.1    Andriole, G.L.2    Wilson, T.H.3
  • 44
    • 84861513919 scopus 로고    scopus 로고
    • Finasteride-related Leydig cell tumour: Report of a case and literature review
    • Berthold D, Lhermitte B, Uffer M, Doerfler A. Finasteride-related Leydig cell tumour: Report of a case and literature review. Andrologia 2012; 44 (Suppl. 1):836-837.
    • (2012) Andrologia , vol.44 , Issue.SUPPL. 1 , pp. 836-837
    • Berthold, D.1    Lhermitte, B.2    Uffer, M.3    Doerfler, A.4
  • 46
    • 84861611201 scopus 로고    scopus 로고
    • Morphometric-stereological and functional epididymal alterations and a decrease in fertility in rats treated with finasteride and after a 30-day posttreatment recovery period
    • Garcia PV, Barbieri MF, Perobelli JE, et al. Morphometric-stereological and functional epididymal alterations and a decrease in fertility in rats treated with finasteride and after a 30-day posttreatment recovery period. Fertil Steril 2012; 97:1444-1451.
    • (2012) Fertil Steril , vol.97 , pp. 1444-1451
    • Garcia, P.V.1    Barbieri, M.F.2    Perobelli, J.E.3
  • 47
    • 51649116908 scopus 로고    scopus 로고
    • Propecia-induced spermatogenic failure: A report of two cases
    • e19
    • Liu KE, Binsaleh S, Lo KC, Jarvi K. Propecia-induced spermatogenic failure: A report of two cases. Fertil Steril 2008; 90:849 e17-849 e19.
    • (2008) Fertil Steril , vol.90 , pp. 849-849
    • Liu, K.E.1    Binsaleh, S.2    Lo, K.C.3    Jarvi, K.4
  • 48
    • 79955013077 scopus 로고    scopus 로고
    • Finasteride-induced secondary infertility associated with sperm DNA damage
    • Tu HYV, Zini A. Finasteride-induced secondary infertility associated with sperm DNA damage. Fertil Steril 2011; 95:2125 e13-2125 e14.
    • (2011) Fertil Steril , vol.95
    • Tu, H.Y.V.1    Zini, A.2
  • 49
    • 73549117681 scopus 로고    scopus 로고
    • 3D-QSAR studies on unsaturated 4-azasteroids as human 5alpha-reductase inhibitors: A self organizing molecular field analysis approach
    • Aggarwal S, Thareja S, Bhardwaj TR, Kumar M. 3D-QSAR studies on unsaturated 4-azasteroids as human 5alpha-reductase inhibitors: A self organizing molecular field analysis approach. Eur J Med Chem 2010; 45:476-481.
    • (2010) Eur J Med Chem , vol.45 , pp. 476-481
    • Aggarwal, S.1    Thareja, S.2    Bhardwaj, T.R.3    Kumar, M.4
  • 50
    • 73249149231 scopus 로고    scopus 로고
    • An overview on 5alpha-reductase inhibitors
    • Aggarwal S, Thareja S, Verma A, et al. An overview on 5alpha-reductase inhibitors. Steroids 2010; 75:109-153.
    • (2010) Steroids , vol.75 , pp. 109-153
    • Aggarwal, S.1    Thareja, S.2    Verma, A.3
  • 51
    • 84858433290 scopus 로고    scopus 로고
    • Synthesis and biological investigation of the b-thiolactone and b-lactam analogs of tetrahydrolipstatin
    • Aubry S, Aubert G, Cresteil T, Crich D. Synthesis and biological investigation of the b-thiolactone and b-lactam analogs of tetrahydrolipstatin. Org Biomol Chem 2012; 10:2629-2632.
    • (2012) Org Biomol Chem , vol.10 , pp. 2629-2632
    • Aubry, S.1    Aubert, G.2    Cresteil, T.3    Crich, D.4
  • 52
    • 81255160846 scopus 로고    scopus 로고
    • New steroidal lactones as 5a-reductase inhibitors and antagonists for the androgen receptor
    • GarridoM, Bratoeff E, Bonilla D, et al. New steroidal lactones as 5a-reductase inhibitors and antagonists for the androgen receptor. J Steroid Biochem Mol Biol 2011; 127:367-373.
    • (2011) J Steroid Biochem Mol Biol , vol.127 , pp. 367-373
    • GarridoM Bratoeff, E.1    Bonilla, D.2
  • 54
    • 0031790128 scopus 로고    scopus 로고
    • Efficacy and safety of luteinizing hormone-releasing hormone antagonist cetrorelix in the treatment of symptomatic benign prostatic hyperplasia
    • Comaru-Schally AM, Brannan W, Schally AV, et al. Efficacy and safety of luteinizing hormone-releasing hormone antagonist cetrorelix in the treatment of symptomatic benign prostatic hyperplasia. J Clin Endocrinol Metab 1998; 83:3826-3831. (Pubitemid 28513557)
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , Issue.11 , pp. 3826-3831
    • Comaru-Schally, A.M.1    Brannan, W.2    Schally, A.V.3    Colcolough, M.4    Monga, M.5
  • 55
    • 44149121728 scopus 로고    scopus 로고
    • Placebo-controlled dose-ranging phase 2 study of subcutaneously administered LHRH antagonist cetrorelix in patients with symptomatic benign prostatic hyperplasia
    • Debruyne F, Gres AA, Arustamov DL. Placebo-controlled dose-ranging phase 2 study of subcutaneously administered LHRH antagonist cetrorelix in patients with symptomatic benign prostatic hyperplasia. Eur Urol 2008; 54:170-177.
    • (2008) Eur Urol , vol.54 , pp. 170-177
    • Debruyne, F.1    Gres, A.A.2    Arustamov, D.L.3
  • 56
    • 77957726553 scopus 로고    scopus 로고
    • Dose-ranging study of the luteinizing hormone-releasing hormone receptor antagonist cetrorelix pamoate in the treatment of patients with symptomatic benign prostatic hyperplasia
    • Debruyne F, Tzvetkov M, Altarac S, Geavlete PA. Dose-ranging study of the luteinizing hormone-releasing hormone receptor antagonist cetrorelix pamoate in the treatment of patients with symptomatic benign prostatic hyperplasia. Urology 2010; 76:927-933.
    • (2010) Urology , vol.76 , pp. 927-933
    • Debruyne, F.1    Tzvetkov, M.2    Altarac, S.3    Geavlete, P.A.4
  • 59
    • 0036604284 scopus 로고    scopus 로고
    • Increased expression of lymphocyte-derived cytokines in benign hyperplastic prostate tissue, identification of the producing cell types, and effect of differentially expressed cytokines on stromal cell proliferation
    • DOI 10.1002/pros.10084
    • Kramer G, Steiner GE, Handisurya A, et al. Increased expression of lymphocyte-derived cytokines in benign hyperplastic prostate tissue, identification of the producing cell types, and effect of differentially expressed cytokines on stromal cell proliferation. Prostate 2002; 52:43-58. (Pubitemid 34553191)
    • (2002) Prostate , vol.52 , Issue.1 , pp. 43-58
    • Kramer, G.1    Steiner, G.E.2    Handisurya, A.3    Stix, U.4    Haitel, A.5    Knerer, B.6    Gessl, A.7    Lee, C.8    Marberger, M.9
  • 60
    • 55749103206 scopus 로고    scopus 로고
    • The relationship between prostate inflammation and lower urinary tract symptoms: Examination of baseline data from the reduce trial
    • Nickel JC, Roehrborn CG, O'Leary MP, et al. The relationship between prostate inflammation and lower urinary tract symptoms: Examination of baseline data from the REDUCE trial. Eur Urol 2008; 54:1379-1384.
    • (2008) Eur Urol , vol.54 , pp. 1379-1384
    • Nickel, J.C.1    Roehrborn, C.G.2    O'Leary, M.P.3
  • 61
    • 0041669594 scopus 로고    scopus 로고
    • Expression and function of pro-inflammatory interleukin IL-17 and IL-17 receptor in normal, benign hyperplastic, and malignant prostate
    • DOI 10.1002/pros.10238
    • Steiner GE, Newman ME, Paikl D, et al. Expression and function of proinflammatory interleukin IL-17 and IL-17 receptor in normal, benign hyperplastic, and malignant prostate. Prostate 2003; 56:171-182. (Pubitemid 36918167)
    • (2003) Prostate , vol.56 , Issue.3 , pp. 171-182
    • Steiner, G.E.1    Newman, M.E.2    Paikl, D.3    Stix, U.4    Memaran-Dagda, N.5    Lee, C.6    Marberger, M.J.7
  • 62
    • 72049091771 scopus 로고    scopus 로고
    • Complex mechanisms in prostatic inflammatory response
    • Djavan B, Eckersberger E, Espinosa G, et al. Complex mechanisms in prostatic inflammatory response. Eur Urol Suppl 2009; 8:872-878.
    • (2009) Eur Urol Suppl , vol.8 , pp. 872-878
    • Djavan, B.1    Eckersberger, E.2    Espinosa, G.3
  • 63
    • 0742305021 scopus 로고    scopus 로고
    • Analysis of the Inflammatory Network in Benign Prostate Hyperplasia and Prostate Cancer
    • DOI 10.1002/pros.10317
    • Konig JE, Senge T, Allhoff EP, Konig W. Analysis of the inflammatory network in benign prostate hyperplasia and prostate cancer. Prostate 2004; 58:121-129. (Pubitemid 38160899)
    • (2004) Prostate , vol.58 , Issue.2 , pp. 121-129
    • Konig, J.E.1    Senge, T.2    Allhoff, E.P.3    Konig, W.4
  • 64
    • 37349032876 scopus 로고    scopus 로고
    • Antagonists of growth-hormone-releasing hormone: An emerging new therapy for cancer
    • DOI 10.1038/ncpendmet0677, PII NCPENDMET0677
    • Schally AV, Varga JL, Engel JB. Antagonists of growth-hormone-releasing hormone: An emerging new therapy for cancer. Nat Clin Pract Endocrinol Metab 2008; 4:33-43. (Pubitemid 350291102)
    • (2008) Nature Clinical Practice Endocrinology and Metabolism , vol.4 , Issue.1 , pp. 33-43
    • Schally, A.V.1    Varga, J.L.2    Engel, J.B.3
  • 65
    • 0028824490 scopus 로고
    • Insulin-like growth factors: The unrecognised oncogenes
    • Westley BR, May FE. Insulin-like growth factors: The unrecognised oncogenes. Br J Cancer 1995; 72:1065-1066.
    • (1995) Br J Cancer , vol.72 , pp. 1065-1066
    • Westley, B.R.1    May, F.E.2
  • 66
    • 0034797098 scopus 로고    scopus 로고
    • A potential autocrine pathway for growth hormone releasing hormone (GHRH) and its receptor in human prostate cancer cell lines
    • DOI 10.1002/pros.1125
    • Chopin LK, Herington AC. A potential autocrine pathway for growth hormone releasing hormone (GHRH) and its receptor in human prostate cancer cell lines. Prostate 2001; 49:116-121. (Pubitemid 32937807)
    • (2001) Prostate , vol.49 , Issue.2 , pp. 116-121
    • Chopin, L.K.1    Herington, A.C.2
  • 67
    • 45549089546 scopus 로고    scopus 로고
    • New approaches to the therapy of various tumors based on peptide analogues
    • DOI 10.1055/s-2008-1073142, Endocrine-related Tumors
    • Schally AV. New approaches to the therapy of various tumors based on peptide analogues. Horm Metab Res 2008; 40:315-322. (Pubitemid 351859442)
    • (2008) Hormone and Metabolic Research , vol.40 , Issue.5 , pp. 315-322
    • Schally, A.V.1
  • 69
    • 56049125706 scopus 로고    scopus 로고
    • Dose-dependent growth inhibition in vivo of PC-3 prostate cancer with a reduction in tumoral growth factors after therapywithGHRHantagonistMZ-J-7-138
    • Heinrich E, Schally AV, Buchholz S, et al. Dose-dependent growth inhibition in vivo of PC-3 prostate cancer with a reduction in tumoral growth factors after therapywithGHRHantagonistMZ-J-7-138. Prostate 2008; 68:1763-1772.
    • (2008) Prostate , vol.68 , pp. 1763-1772
    • Heinrich, E.1    Schally, A.V.2    Buchholz, S.3
  • 70
    • 84857137088 scopus 로고    scopus 로고
    • Inhibitory effects of antagonists of growth hormone releasing hormone on experimental prostate cancers are associated with upregulation of wild-type p53 and decrease in p21 and mutant p53 proteins
    • Stangelberger A, Schally AV, Rick FG, et al. Inhibitory effects of antagonists of growth hormone releasing hormone on experimental prostate cancers are associated with upregulation of wild-type p53 and decrease in p21 and mutant p53 proteins. Prostate 2012; 72:555-565.
    • (2012) Prostate , vol.72 , pp. 555-565
    • Stangelberger, A.1    Schally, A.V.2    Rick, F.G.3
  • 71
    • 84857137033 scopus 로고    scopus 로고
    • Antagonists of growth hormonereleasing hormone inhibit growth of androgen-independent prostate cancer through inactivation of ERK and Akt kinases
    • Rick FG, Schally AV, Szalontay L, et al. Antagonists of growth hormonereleasing hormone inhibit growth of androgen-independent prostate cancer through inactivation of ERK and Akt kinases. Proc Natl Acad Sci USA 2012; 109:1655-1660.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 1655-1660
    • Rick, F.G.1    Schally, A.V.2    Szalontay, L.3
  • 73
    • 84862159053 scopus 로고    scopus 로고
    • BPH: Hormone antagonists for two-pronged attack on BPH
    • Clyn M. BPH: Hormone antagonists for two-pronged attack on BPH. Nat Rev Urol 2012; 9:235.
    • (2012) Nat Rev Urol , Issue.9 , pp. 235
    • Clyn, M.1


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