Detection of acrolein-derived cyclic DNA adducts in human cells by monoclonal antibodies

Chemical Research in Toxicology

Volumn 25, Issue 12, 2012, Pages 2788-2795

  Pan, Jishen ^a   Awoyemi, Bisola ^a   Xuan, Zhuoli ^a   Vohra, Priya ^a   Wang, Hsiang Tsui ^b   Dyba, Marcin ^a   Greenspan, Emily ^a   Fu, Ying ^a   Creswell, Karen ^a   Zhang, Lihua ^a   Berry, Deborah ^a   Tang, Moon Shong ^b   Chung, Fung Lung ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,N6 ETHENODEOXYADENOSINE; 8 OXO DEOXYGUANOSINE; ACROLEIN; ACROLEIN DERIVED 1 N2 PROPANODEOXYGUANOSINE; ACROLEIN DERIVED 1 N2 PROPANODEOXYGUANOSINE MONOCLONAL ANTIBODY; ADENOSINE; CIRCULAR DNA; CROTONALDEHYDE; GUANOSINE; MONOCLONAL ANTIBODY; TRANS 4 HYDROXY 2 NONENAL DERIVED 1 N2 PROPANODEOXYGUANOSINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA ADDUCT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

ACROLEIN; AIR POLLUTANTS; ANIMALS; ANTIBODIES, MONOCLONAL; BIOLOGICAL MARKERS; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; DNA ADDUCTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HT29 CELLS; HUMANS; KERATINOCYTES; MICE; MICE, INBRED BALB C; MOUTH; TANDEM MASS SPECTROMETRY;

EID: 84871195531     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx3004104     Document Type: Article

References (35)

1. Stevens, J. F. and Maier, C. S. (2008) Acrolein: Sources, metabolism, and biomolecular interactions relevant to human health and disease Mol. Nutr. Food Res. 52, 7-25 (Pubitemid 351211799)
2. - 1995 Evaluation of the carcinogenic risk of chemicals to humans, dry cleaning, some chlorinated solvents and other industrial chemicals, IARC Monograph, Vol. 63, pp 337-372, International Agency for Research on Cancer, Lyon.
3. Nair, U., Bartsch, H., and Nair, J. (2007) Lipid peroxidation-induced DNA damage in cancer-prone inflammatory diseases: A review of published adduct types and levels in humans Free Radical Biol. Med. 43, 1109-1120 (Pubitemid 47374441)
4. Uchida, K., Kanematsu, M., Sakai, K., Matsuda, T., Hattori, N., Mizuno, Y., Suzuki, D., Miyata, T., Noguchi, N., Niki, E., and Osawa, T. (1998) Protein-bound acrolein: Potential markers for oxidative stress Proc. Natl. Acad. Sci. U.S.A. 95, 4882-4887 (Pubitemid 28208519)
5. Chung, F.-L., Chen, H.-J., and Nath, R. G. (1996) Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts Carcinogenesis 17, 2105-2111 (Pubitemid 26372045)
6. Pan, J. and Chung, F.-L. (2002) Formation of cyclic deoxyguanosine adducts from ω-3 and ω-6 polyunsaturated fatty acids under oxidative conditions Chem. Res. Toxicol. 15, 367-372 (Pubitemid 34241375)
7. 2-deoxyguanosine adducts of the α,β-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal Chem. Res. Toxicol. 22, 759-778
8. 2-propano-deoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde Cancer Res. 44, 990-995 (Pubitemid 14152780)
9. 2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans Proc. Natl. Acad. Sci. U.S.A. 91, 7491-7495
10. 2-propanodeoxyguanosine adducts in human lung by liquid chromatography-electrospray ionization-tandem mass spectrometry Chem. Res. Toxicol. 20, 565-571 (Pubitemid 46762089)
11. 2- propanodeoxyguanosine adducts mediated by amino acids, proteins, and cell lysates Chem. Res. Toxicol. 25, 1921-1928
12. - 1999 Exocyclic DNA Adducts in Mutagenesis and Carcinogenesis, in Proceedings of the 2nd international conference. Heidelberg, Germany, September 1998, IARC Scientific Publication No. 150, pp 1-361, International Agency for Research on Cancer, Lyon.
13. VanderVeen, L. A., Hashim, M. F., Nechev, L. V., Harris, T. M., Harris, C. M., and Marnett, L. J. (2001) Evaluation of the mutagenic potential of the principal DNA adduct of acrolein J. Biol. Chem. 276, 9066-9070
14. Benamira, M., Singh, U., and Marnett, L. J. (1992) Site-specific frameshift mutagenesis by a propanodeoxyguanosine adduct positioned in the (CpG)4 hot-spot of Salmonella typhimurium his D3052 carried on an M13 vector J. Biol. Chem. 267, 22392-22400
15. Moriya, M., Zhang, W., Johnson, F., and Grollman, A. P. (1994) Mutagenic potency of exocyclic DNA adducts: marked differences between Escherichia coli and simian kidney cells Proc. Natl. Acad. Sci. U.S.A. 91, 11899-11903 (Pubitemid 24368571)
16. Yang, I, Y., Hossain, M., Miller, H., Khullar, S., Johnson, F., Grollman, A., and Moriya, M. (2001) Responses to the major acrolein-derived deoxyguanosine adduct in Escherichia coli J. Biol. Chem. 276, 9071-9076
17. Yang, I. Y., Chan, G., Miller, H., Huang, Y., Torres, M. C., Johnson, F., and Moriya, M. (2002) Mutagenesis by acrolein-derived propanodeoxyguanosine adducts in human cells Biochemistry 41, 13826-13832 (Pubitemid 35332721)
18. Kanuri, M, Minko, I. G., Nechev, L. V., Harris, T. M., Harris, C. M., and Lloyd, R. S. (2002) Error prone translesion synthesis past γ- hydroxypropano deoxyguanosine, the primary acrolein-derived adduct in mammalian cells J. Biol. Chem. 277, 18257-18265 (Pubitemid 34952369)
19. Wang, H. T., Zhang, S., Hu, Y., and Tang, M. S. (2009) Mutagenicity and sequence specificity of acrolein-DNA adducts Chem. Res. Toxicol. 22, 511-517
20. Marnett, L. J., Hurd, H. K., Hollstein, M. C., Levin, D. E., Esterbauer, H., and Ames, B. N. (1985) Naturally occurring carbonyl compounds are mutagens in Salmonella tester strain TA104 Mutat. Res. 148, 25-34 (Pubitemid 15151659)
21. Foiles, P. G., Akerkar, S. A., and Chung, F.-L. (1989) Application of an immunoassay for cyclic acrolein deoxyguanosine adducts to assess their formation in DNA of Salmonella typhimurium under conditions of mutation induction by acrolein Carcinogenesis 10, 87-90 (Pubitemid 19032089)
22. Foiles, P. G., Akerkar, S. A., Miglietta, L. M., and Chung, F.-L. (1990) Formation of cyclic deoxyguanosine adducts in Chinese hamster ovary cells by acrolein and crotonaldehyde Carcinogenesis 11, 2059-2061 (Pubitemid 20375956)
23. Wang, H. T., Hu, Y., Tong, D., Huang, J., Gu, L., Wu, X. R., Chung, F.-L., Li, G. M., and Tang, M. S. (2012) Effect of carcinogenic acrolein on DNA repair and mutagenic susceptibility J. Biol. Chem. 287, 12379-12386
24. Feng, Z., Hu, W., Hu, Y., and Tang, M. S. (2006) Acrolein is a major cigarette-related lung cancer agent: preferential binding at p53 mutational hotspots and inhibition of DNA repair Proc. Natl. Acad. Sci. U.S.A. 103, 15404-15409 (Pubitemid 44625604)
25. Pan, J., Keffer, J., Emami, A., Ma, X., Lan, R., Goldman, R., and Chung, F.-L. (2009) Acrolein-derived DNA adduct formation in human colon cancer cells: its role in apoptosis induction by docosahexaenoic acid Chem. Res. Toxicol. 22, 798-806
26. 2-propanodeoxyguanosine adducts derived from enals Anal. Biochem. 348, 15-23 (Pubitemid 41796452)
27. 32P -postlabeling/solid-phase extraction/HPLC method: Blocking its artifact formation with glutathione Anal. Biochem. 374, 163-172
28. Erlanger, B. F. and Berser, S. M. (1964) Antibodies specific for ribonucleosides and ribonucleotides and their reaction with DNA Proc. Natl. Acad. Sci. U.S.A. 52, 68-74
29. Foiles, P. G., Chung, F.-L., and Hecht, S. S. (1987) Development of a monoclonal antibody-based immunoassay for cyclic DNA adducts resulting from exposure to crotonaldehyde Cancer Res. 47, 360-363 (Pubitemid 17009591)
30. Okahashi, Y., Iwamoto, T., Suzuki, N., Shibutani, S., Sugiura, S., Itoh, S., Nishiwaki, T., Ueno, S., and Mori, T. (2010) Quantitative detection of 4-hydroxyequilenin-DNA adducts in mammalian cells using an immunoassay with a novel monoclonal antibody Nucleic Acids Res. 38, e133
31. Schwartz, J. L., Muscat, J. E., Baker, V., Larios, E., Stephenson, G. D., Guo, W., Xie, T., Gu, X., and Chung, F.-L. (2003) Oral cytology assessment by flow cytometry of DNA adducts, aneuploidy, proliferation and apoptosis shows differences between smokers and non-smokers Oral Oncol. 39, 842-854 (Pubitemid 38379590)
32. Sanchez, A. M., Minko, I. G., Kurtz, A. J., Kanuri, M., Moriya, M., and Lloyd, R. S. (2003) Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived α-HOPdG and γ-HOPdG regioisomeric deoxyguanosine adducts Chem. Res. Toxicol. 16, 1019-1028 (Pubitemid 37047920)
33. Kawai, Y., Furuhata, A., Toyokuni, S., Aratani, Y., and Uchida, K. (2003) Formation of acrolein-derived 2′-deoxyadenosine adduct in an iron-induced carcinogenesis model J. Biol. Chem. 278, 50346-50354 (Pubitemid 37548877)
34. Santella, R. M. (1999) Immunological methods for detection of carcinogen-DNA damage in humans Cancer Epidemiol., Biomarkers Prev. 8, 733-739 (Pubitemid 29445009)
35. Greenspan, E. J., Lee, H., Dyba, M., Pan, J., Mekambi, K., Johnson, T., Blancato, J., Mueller, S., Berry, D. L., and Chung, F. L. (2012) High-throughput, quantitative analysis of acrolein-derived DNA adducts in human oral cells by immunohistochemistry J. Histochem. Cytochem. 60, 844-853