메뉴 건너뛰기




Volumn 29, Issue 5, 2012, Pages 426-438

Probiotics, prebiotics, synbiotics: Is there enough evidence to support their use in colorectal cancer surgery?

Author keywords

Colorectal cancer; Probiotics; Review; Surgery; Synbiotics

Indexed keywords


EID: 84871195225     PISSN: 02534886     EISSN: None     Source Type: Journal    
DOI: 10.1159/000345580     Document Type: Review
Times cited : (29)

References (82)
  • 1
    • 78650883928 scopus 로고    scopus 로고
    • The impact of pre-and/or probiotics on human colonic metabolism: Does it affect human health?
    • De Preter V, Hamer HM, Windey K, Verbeke K: The impact of pre-and/or probiotics on human colonic metabolism: does it affect human health? Mol Nutr Food Res 2003;55: 46-57.
    • (2003) Mol Nutr Food Res , vol.55 , pp. 46-57
    • De Preter, V.1    Hamer, H.M.2    Windey, K.3    Verbeke, K.4
  • 2
    • 0026586542 scopus 로고
    • Comparison of fermentation reactions in different regions of the human colon
    • Macfarlane GT, Gibson GR, Cummings JH: Comparison of fermentation reactions in different regions of the human colon. J Appl Bacteriol 1992;72:57-64.
    • (1992) J Appl Bacteriol , vol.72 , pp. 57-64
    • MacFarlane, G.T.1    Gibson, G.R.2    Cummings, J.H.3
  • 3
    • 84858590812 scopus 로고    scopus 로고
    • Gut microbiota: Next frontier in understanding human health and development of biotherapeutics
    • Prakash S, Rodes L, Coussa-Charley M, Tomaro-Duchesneau C: Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biologics 2011;5:71-86.
    • (2011) Biologics , vol.5 , pp. 71-86
    • Prakash, S.1    Rodes, L.2    Coussa-Charley, M.3    Tomaro-Duchesneau, C.4
  • 4
    • 12744255185 scopus 로고    scopus 로고
    • The effects of probiotics on colon cancer development
    • Rafter J: The effects of probiotics on colon cancer development. Nutr Res Rev 2004;17: 277-284.
    • (2004) Nutr Res Rev , vol.17 , pp. 277-284
    • Rafter, J.1
  • 5
    • 84985161098 scopus 로고
    • Probiotics in man and animals
    • Fuller R: Probiotics in man and animals. J Appl Bacteriol 1986;66:365-378.
    • (1986) J Appl Bacteriol , vol.66 , pp. 365-378
    • Fuller, R.1
  • 6
    • 0029013322 scopus 로고
    • Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics
    • Gibson GR, Roberfroid MB: Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 1995;125:1401-1412.
    • (1995) J Nutr , vol.125 , pp. 1401-1412
    • Gibson, G.R.1    Roberfroid, M.B.2
  • 7
    • 23044491563 scopus 로고    scopus 로고
    • Introducing inulin-type fructans
    • Roberfroid MB: Introducing inulin-type fructans. Br J Nutr 2006;93:S13-S25.
    • (2006) Br J Nutr , vol.93
    • Roberfroid, M.B.1
  • 8
    • 77952894880 scopus 로고    scopus 로고
    • Food-based strategies to modulate the composition of the intestinal microbiota and their associated health effects
    • Bosscher D, Breynaert A, Pieters L, Hermans N: Food-based strategies to modulate the composition of the intestinal microbiota and their associated health effects. J Physiol Pharmacol 2009;60:S5-S11.
    • (2009) J Physiol Pharmacol , vol.60
    • Bosscher, D.1    Breynaert, A.2    Pieters, L.3    Hermans, N.4
  • 9
    • 84858768479 scopus 로고    scopus 로고
    • New insights into the impact of the intestinal microbiota on health and disease: A symposium report
    • Thomas LV, Ockhuizen T: New insights into the impact of the intestinal microbiota on health and disease: a symposium report. Br J Nutr 2012;107(suppl 1):S1-S13.
    • (2012) Br J Nutr , vol.107 , Issue.SUPPL. 1
    • Thomas, L.V.1    Ockhuizen, T.2
  • 10
    • 0036849544 scopus 로고    scopus 로고
    • Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats
    • Femia AP, Luceri C, Dolara P, Giannini A, Biggeri A, Salvadori M, Clune Y, Collins KJ, Paglierani M, Caderni G: Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats. Carcinogenesis 2002;23:1953-1960.
    • (2002) Carcinogenesis , vol.23 , pp. 1953-1960
    • Femia, A.P.1    Luceri, C.2    Dolara, P.3    Giannini, A.4    Biggeri, A.5    Salvadori, M.6    Clune, Y.7    Collins, K.J.8    Paglierani, M.9    Caderni, G.10
  • 11
    • 77954751968 scopus 로고    scopus 로고
    • The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibition
    • Ma EL, Choi YJ, Choi J, Pothoulakis C, Rhee SH, Im E: The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibition. Int J Cancer 2002;127: 780-790.
    • (2002) Int J Cancer , vol.127 , pp. 780-790
    • Ma, E.L.1    Choi, Y.J.2    Choi, J.3    Pothoulakis, C.4    Rhee, S.H.5    Im, E.6
  • 12
    • 33751112482 scopus 로고    scopus 로고
    • Probiotics prebiotics and synbiotics: A role in chemoprevention for colorectal cancer?
    • Geier MS, Butler RN, Howarth GS: Probiotics, prebiotics and synbiotics: a role in chemoprevention for colorectal cancer? Cancer Biol Ther 2006;5:1265-1269.
    • (2006) Cancer Biol Ther , vol.5 , pp. 1265-1269
    • Geier, M.S.1    Butler, R.N.2    Howarth, G.S.3
  • 13
    • 0031817509 scopus 로고    scopus 로고
    • What is the role of mechanical bowel preparation in patients undergoing colorectal surgery?
    • Platell C, Hall J: What is the role of mechanical bowel preparation in patients undergoing colorectal surgery? Dis Colon Rectum 2011;41:875-882.
    • (2011) Dis Colon Rectum , vol.41 , pp. 875-882
    • Platell, C.1    Hall, J.2
  • 14
    • 0035003391 scopus 로고    scopus 로고
    • Role of the gut lymphatic system in multiple failure
    • Deitch EA: Role of the gut lymphatic system in multiple failure. Curr Opin Crit Care 2001;7:92-98.
    • (2001) Curr Opin Crit Care , vol.7 , pp. 92-98
    • Deitch, E.A.1
  • 15
    • 0030041078 scopus 로고    scopus 로고
    • Econutrition and health maintanance - A new concept to prevent GI inflammation, ulceration and sepsis
    • Bengmark S: Econutrition and health maintanance-a new concept to prevent GI inflammation, ulceration and sepsis. Clin Nutr 1996;15:1-10.
    • (1996) Clin Nutr , vol.15 , pp. 1-10
    • Bengmark, S.1
  • 17
    • 0038177618 scopus 로고    scopus 로고
    • Nosocomial infections in adult intensive care units
    • Vincent JL: Nosocomial infections in adult intensive care units. Lancet 2003;361:2068-2077.
    • (2003) Lancet , vol.361 , pp. 2068-2077
    • Vincent, J.L.1
  • 18
    • 0035137243 scopus 로고    scopus 로고
    • Uninterrupted perioperative enteral nutrition
    • Bengmark S, Andersson R, Angiante G: Uninterrupted perioperative enteral nutrition. Clin Nutr 2001;20:11.
    • (2001) Clin Nutr , vol.20 , pp. 11
    • Bengmark, S.1    Andersson, R.2    Angiante, G.3
  • 19
    • 33947716253 scopus 로고    scopus 로고
    • The use of pre-, pro-and synbiotics in adult intensive care unit patients: Systematic review
    • Watkinson PJ, Barber VS, Dark P, Young JD: The use of pre-, pro-and synbiotics in adult intensive care unit patients: systematic review. Clin Nutr 2007;26:182-192.
    • (2007) Clin Nutr , vol.26 , pp. 182-192
    • Watkinson, P.J.1    Barber, V.S.2    Dark, P.3    Young, J.D.4
  • 20
    • 0031959714 scopus 로고    scopus 로고
    • Ecological control of the gastrointestinal tract the role of probiotic flora
    • Bengmark S: Ecological control of the gastrointestinal tract. The role of probiotic flora. Gut 1998;42:2-7.
    • (1998) Gut , vol.42 , pp. 2-7
    • Bengmark, S.1
  • 21
    • 77955521970 scopus 로고    scopus 로고
    • Preoperative synbiotic bowel conditioning for elective colorectal surgery
    • Horvat M, Krebs B, Potrc S, Ivanecz A, Kompan L: Preoperative synbiotic bowel conditioning for elective colorectal surgery. Wien Klin Wochenschr 2010;122(suppl 2):26-30.
    • (2010) Wien Klin Wochenschr , vol.122 , Issue.SUPPL. 2 , pp. 26-30
    • Horvat, M.1    Krebs, B.2    Potrc, S.3    Ivanecz, A.4    Kompan, L.5
  • 22
    • 34248361622 scopus 로고    scopus 로고
    • Randomized clinical trial of effect of synbiotics, neomycin and mechanical bowel preparation on intestinal barrier function in patients undergoing colectomy
    • Reddy BS, Macfie J, Gatt M, Larsen CN, Jensen SS, Leser TD: Randomized clinical trial of effect of synbiotics, neomycin and mechanical bowel preparation on intestinal barrier function in patients undergoing colectomy. Br J Surg 2007;94:546-554.
    • (2007) Br J Surg , vol.94 , pp. 546-554
    • Reddy, B.S.1    MacFie, J.2    Gatt, M.3    Larsen, C.N.4    Jensen, S.S.5    Leser, T.D.6
  • 24
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • Martin GS, Mannino DM, Eaton S, Moss M: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003;348:1546-1554.
    • (2003) N Engl J Med , vol.348 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 25
    • 0032930613 scopus 로고    scopus 로고
    • Risk factors associated with intraabdominal infections: A prospective multicenter study
    • Wacha H, Hau T, Dittmer R, Ohmann C: Risk factors associated with intraabdominal infections: a prospective multicenter study. Langenbecks Arch Surg 1999;384:24-32.
    • (1999) Langenbecks Arch Surg , vol.384 , pp. 24-32
    • Wacha, H.1    Hau, T.2    Dittmer, R.3    Ohmann, C.4
  • 26
    • 84857656943 scopus 로고    scopus 로고
    • Preoperative probiotics decrease postoperative infectious complications of colorectal cancer
    • Zhang JW, Du P, Gao J, Yang BR, Fang WJ, Ying CM: Preoperative probiotics decrease postoperative infectious complications of colorectal cancer. Am J Med Sci 2012;343: 199-205.
    • (2012) Am J Med Sci , vol.343 , pp. 199-205
    • Zhang, J.W.1    Du, P.2    Gao, J.3    Yang, B.R.4    Fang, W.J.5    Ying, C.M.6
  • 29
    • 0032471125 scopus 로고    scopus 로고
    • The role of interdigestive small bowel motility in the regulation of gut microflora, bacterial overgrowth, and bacterial translocation in rats
    • Nieuwenhuijs VB, Verheem A, Duijvenbode-Beumer H, Visser MR, Verhoef J, Gooszen HG, Akkermans LM: The role of interdigestive small bowel motility in the regulation of gut microflora, bacterial overgrowth, and bacterial translocation in rats. Ann Surg 1998;228:188-193.
    • (1998) Ann Surg , vol.228 , pp. 188-193
    • Nieuwenhuijs, V.B.1    Verheem, A.2    Duijvenbode-Beumer, H.3    Visser, M.R.4    Verhoef, J.5    Gooszen, H.G.6    Akkermans, L.M.7
  • 30
    • 0028965103 scopus 로고
    • Elemental diet and iv-TPN-induced bacterial translocation is associated with loss of intestinal mucosal barrier function against bacteria
    • Deitch EA, Dazhong X, Naruhn MB, Deitch DC, Qi L, Marino AA: Elemental diet and iv-TPN-induced bacterial translocation is associated with loss of intestinal mucosal barrier function against bacteria. Ann Surg 1995; 221:299-307.
    • (1995) Ann Surg , vol.221 , pp. 299-307
    • Deitch, E.A.1    Dazhong, X.2    Naruhn, M.B.3    Deitch, D.C.4    Qi, L.5    Marino, A.A.6
  • 31
    • 0037425743 scopus 로고    scopus 로고
    • Gut flora in health and disease
    • Guarner F, Malagelada JR: Gut flora in health and disease. Lancet 2003;361:512-519.
    • (2003) Lancet , vol.361 , pp. 512-519
    • Guarner, F.1    Malagelada, J.R.2
  • 33
    • 0037182875 scopus 로고    scopus 로고
    • A randomized, prospective, double-blind evaluation of selective bowel decontamination
    • Hellinger WC, Yao JD, Alvarez S: A randomized, prospective, double-blind evaluation of selective bowel decontamination. Transplantation 2002;73:1904-1909.
    • (2002) Transplantation , vol.73 , pp. 1904-1909
    • Hellinger, W.C.1    Yao, J.D.2    Alvarez, S.3
  • 34
    • 22144479779 scopus 로고    scopus 로고
    • Effect of pH and antibiotics on microbial overgrowth in the stomachs and duodena of patients undergoing percutaneous endoscopic gastrostomy feeding
    • O'May GA, Reynolds N, Smith AR, Kennedy A, Macfarlane GT: Effect of pH and antibiotics on microbial overgrowth in the stomachs and duodena of patients undergoing percutaneous endoscopic gastrostomy feeding. J Clin Microbiol 2005;43:3059-3065.
    • (2005) J Clin Microbiol , vol.43 , pp. 3059-3065
    • O'May, G.A.1    Reynolds, N.2    Smith, A.R.3    Kennedy, A.4    MacFarlane, G.T.5
  • 35
    • 4444242774 scopus 로고    scopus 로고
    • Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens
    • Servin AL: Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens. FEMS Microbiol Rev 2004;28:405-440.
    • (2004) FEMS Microbiol Rev , vol.28 , pp. 405-440
    • Servin, A.L.1
  • 36
    • 33645900573 scopus 로고    scopus 로고
    • Towards understanding molecular modes of probiotic action
    • Marco ML, Pavan S, Kleerebezem M: Towards understanding molecular modes of probiotic action. Curr Opin Biotechnol 2006;17:204-210.
    • (2006) Curr Opin Biotechnol , vol.17 , pp. 204-210
    • Marco, M.L.1    Pavan, S.2    Kleerebezem, M.3
  • 38
    • 1642274741 scopus 로고    scopus 로고
    • Functional modulation of enterocytes by Gram-positive and Gram-negative microorganisms
    • Otte JM, Podolsky DK: Functional modulation of enterocytes by Gram-positive and Gram-negative microorganisms. Am J Physiol Gastrointest Liver Physiol 2004;286: 613-626.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286 , pp. 613-626
    • Otte, J.M.1    Podolsky, D.K.2
  • 39
    • 33644937046 scopus 로고    scopus 로고
    • Identification of strong interleukin-inducing lactic acid bacteria which down-regulate T helper type 2 cytokines
    • Niers LE, Timmerman HM, Rijkers GT, Van Bleek GM, van Uden NO, Knol EF: Identification of strong interleukin-inducing lactic acid bacteria which down-regulate T helper type 2 cytokines. Clin Exp Allergy 2005;35: 1481-1489.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1481-1489
    • Niers, L.E.1    Timmerman, H.M.2    Rijkers, G.T.3    Van Bleek, G.M.4    Van Uden, N.O.5    Knol, E.F.6
  • 40
    • 33750374802 scopus 로고    scopus 로고
    • Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery: A randomized controlled trial
    • Sugawara G, Nagino M, Nishio H, Ebata T, Takagi K, Asahara T: Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery: a randomized controlled trial. Ann Surg 2006;244:706-714.
    • (2006) Ann Surg , vol.244 , pp. 706-714
    • Sugawara, G.1    Nagino, M.2    Nishio, H.3    Ebata, T.4    Takagi, K.5    Asahara, T.6
  • 41
    • 20444503737 scopus 로고    scopus 로고
    • Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin
    • Smits HH, Engering A, van der Kleij D, de Jong EC, Schipper K, van Capel TM: Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J Allergy Clin Immunol 2005;115:1260-1267.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 1260-1267
    • Smits, H.H.1    Engering, A.2    Van Der Kleij, D.3    De Jong, E.C.4    Schipper, K.5    Van Capel, T.M.6
  • 42
    • 84857663981 scopus 로고    scopus 로고
    • Pro-and synbiotics to prevent sepsis in major surgery and severe emergencies
    • Bengmark S: Pro-and synbiotics to prevent sepsis in major surgery and severe emergencies. Nutrients 2012;4:91-111.
    • (2012) Nutrients , vol.4 , pp. 91-111
    • Bengmark, S.1
  • 43
    • 0036895047 scopus 로고    scopus 로고
    • A prospective randomised study of the probiotic Lactobacillus plantarum 299v on indices of gut barrier function in elective surgical patients
    • McNaught CE, Woodcock NP, MacFie J, Mitchell CJ: A prospective randomised study of the probiotic Lactobacillus plantarum 299v on indices of gut barrier function in elective surgical patients. Gut 2002;51:827-831.
    • (2002) Gut , vol.51 , pp. 827-831
    • McNaught, C.E.1    Woodcock, N.P.2    MacFie, J.3    Mitchell, C.J.4
  • 44
    • 68849084123 scopus 로고    scopus 로고
    • Does the use of probiotics/synbiotics prevent postoperative infections in patients undergoing abdominal surgery? A meta-analysis of randomized controlled trials
    • Pitsouni E, Alexiou V, Saridakis V, Peppas G, Falagas ME: Does the use of probiotics/synbiotics prevent postoperative infections in patients undergoing abdominal surgery? A meta-analysis of randomized controlled trials. Eur J Clin Pharmacol 2009;65:561-570.
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 561-570
    • Pitsouni, E.1    Alexiou, V.2    Saridakis, V.3    Peppas, G.4    Falagas, M.E.5
  • 45
    • 84873081468 scopus 로고    scopus 로고
    • A metaanalysis of probiotic and synbiotic use in elective surgery does nutrition modulation of the gut microbiome improve clinical outcome?
    • Epub ahead of print
    • Kinross JM, Markar S, Karthikesalingam A, Chow A, Penney N, Silk D, Darzi A: A metaanalysis of probiotic and synbiotic use in elective surgery: does nutrition modulation of the gut microbiome improve clinical outcome? JPEN J Parenter Enteral Nutr 2012, Epub ahead of print.
    • (2012) JPEN J Parenter Enteral Nutr
    • Kinross, J.M.1    Markar, S.2    Karthikesalingam, A.3    Chow, A.4    Penney, N.5    Silk, D.6    Darzi, A.7
  • 46
    • 79958034988 scopus 로고    scopus 로고
    • Use of probiotics as prophylaxis for postoperative infections
    • Jeppsson B, Mangell P, Thorlacius H: Use of probiotics as prophylaxis for postoperative infections. Nutrients 2011;3:604-612.
    • (2011) Nutrients , vol.3 , pp. 604-612
    • Jeppsson, B.1    Mangell, P.2    Thorlacius, H.3
  • 47
    • 1642451908 scopus 로고    scopus 로고
    • Randomised clinical trial of synbiotic therapy in elective surgical patients
    • Anderson ADG, McNaught CE, Jain PK, MacFie J: Randomised clinical trial of synbiotic therapy in elective surgical patients. Gut 2004;53:241-245.
    • (2004) Gut , vol.53 , pp. 241-245
    • Anderson, A.D.G.1    McNaught, C.E.2    Jain, P.K.3    MacFie, J.4
  • 48
    • 0036295030 scopus 로고    scopus 로고
    • Early enteral supply of fiber and Lactobacilli versus conventional nutrition: A controlled trial in patients with major abdominal surgery
    • Rayes N, Hansen S, Seehofer D, Muller AR, Serke S, Bengmark S, Neuhaus P: Early enteral supply of fiber and Lactobacilli versus conventional nutrition: a controlled trial in patients with major abdominal surgery. Nutrition 2002;18:609-615.
    • (2002) Nutrition , vol.18 , pp. 609-615
    • Rayes, N.1    Hansen, S.2    Seehofer, D.3    Muller, A.R.4    Serke, S.5    Bengmark, S.6    Neuhaus, P.7
  • 49
    • 33750374802 scopus 로고    scopus 로고
    • Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery: A randomized controlled trial
    • Sugawara G, Nagino M, Nishio H, Ebata T, Takagi K, Asahara T, Nomoto K, Nimura Y: Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery: a randomized controlled trial. Ann Surg 2006;244:706-714.
    • (2006) Ann Surg , vol.244 , pp. 706-714
    • Sugawara, G.1    Nagino, M.2    Nishio, H.3    Ebata, T.4    Takagi, K.5    Asahara, T.6    Nomoto, K.7    Nimura, Y.8
  • 50
    • 34347330287 scopus 로고    scopus 로고
    • Effect of enteral nutrition and synbiotics on bacterial infection rates after pylorus-preserving pancreatoduodenectomy: A randomized, double-blind trial
    • Rayes N, Seehofer D, Theruvath T, Mogl M, Langrehr JM, Nussler NC, Bengmark S, Neuhaus P: Effect of enteral nutrition and synbiotics on bacterial infection rates after pylorus-preserving pancreatoduodenectomy: a randomized, double-blind trial. Ann Surg 2007;246:36-41.
    • (2007) Ann Surg , vol.246 , pp. 36-41
    • Rayes, N.1    Seehofer, D.2    Theruvath, T.3    Mogl, M.4    Langrehr, J.M.5    Nussler, N.C.6    Bengmark, S.7    Neuhaus, P.8
  • 51
    • 34248157583 scopus 로고    scopus 로고
    • Synbiotic control of inflammation and infection in severe acute pancreatitis: A prospective, randomized, double blind study
    • Olah A, Belagyi T, Poto L, Romics L Jr, Bengmark S: Synbiotic control of inflammation and infection in severe acute pancreatitis: a prospective, randomized, double blind study. Hepatogastroenterology 2007;54: 590-594.
    • (2007) Hepatogastroenterology , vol.54 , pp. 590-594
    • Olah, A.1    Belagyi, T.2    Poto, L.3    Romics Jr., L.4    Bengmark, S.5
  • 53
    • 33749001956 scopus 로고    scopus 로고
    • Benefits of a synbiotic formula (synbiotic 2000 forte) in critically ill trauma patients: Early results of a randomized controlled trial
    • Kotzampassi K, Giamarellos-Bourboulis EJ, Voudouris A, Kazamias P, Eleftheriadis E: Benefits of a synbiotic formula (synbiotic 2000 forte) in critically ill trauma patients: early results of a randomized controlled trial. World J Surg 2006;30:1848-1855.
    • (2006) World J Surg , vol.30 , pp. 1848-1855
    • Kotzampassi, K.1    Giamarellos-Bourboulis, E.J.2    Voudouris, A.3    Kazamias, P.4    Eleftheriadis, E.5
  • 54
    • 34247884362 scopus 로고    scopus 로고
    • Synbiotics, prebiotics, glutamine, or peptide in early enteral nutrition: A randomized study in trauma patients
    • Spindler-Vesel A, Bengmark S, Vovk I, Cerovic O, Kompan L: Synbiotics, prebiotics, glutamine, or peptide in early enteral nutrition: a randomized study in trauma patients. JPEN J Parenter Enteral Nutr 2007;31:119-126.
    • (2007) JPEN J Parenter Enteral Nutr , vol.31 , pp. 119-126
    • Spindler-Vesel, A.1    Bengmark, S.2    Vovk, I.3    Cerovic, O.4    Kompan, L.5
  • 57
    • 78649987442 scopus 로고    scopus 로고
    • Randomised clinical trial: The effects of perioperative probiotic treatment on barrier function and post-operative infectious complications in colorectal cancer surgery - A double-blind study
    • Liu Z, Qin H, Yang Z, Xia Y, Liu W, Yang J, Jiang Y, Zhang H, Yang Z, Wang Y, Zheng Q: Randomised clinical trial: the effects of perioperative probiotic treatment on barrier function and post-operative infectious complications in colorectal cancer surgery-a double-blind study. Aliment Pharmacol Ther 2011;33:50-63.
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 50-63
    • Liu, Z.1    Qin, H.2    Yang, Z.3    Xia, Y.4    Liu, W.5    Yang, J.6    Jiang, Y.7    Zhang, H.8    Yang, Z.9    Wang, Y.10    Zheng, Q.11
  • 61
    • 3042635740 scopus 로고    scopus 로고
    • Antigenotoxicity of probiotics and prebiotics on faecal water induced DNA damage in human colon adenocarcinoma cells
    • Burns AJ, Rowland IR: Antigenotoxicity of probiotics and prebiotics on faecal water induced DNA damage in human colon adenocarcinoma cells. Mutat Res 2004;551:233-243.
    • (2004) Mutat Res , vol.551 , pp. 233-243
    • Burns, A.J.1    Rowland, I.R.2
  • 62
    • 3042847528 scopus 로고    scopus 로고
    • Immunomodulatory and antitumor effects in vivo by the cytoplasmic fraction of Lactobacillus casei and Bifidobacterium longum
    • Lee JW, Shin JG, Kim EH, Kang HE, Yim IB, Kim JY, Joo HG, Woo HJ: Immunomodulatory and antitumor effects in vivo by the cytoplasmic fraction of Lactobacillus casei and Bifidobacterium longum. J Vet Sci 2004;5: 41-48.
    • (2004) J Vet Sci , vol.5 , pp. 41-48
    • Lee, J.W.1    Shin, J.G.2    Kim, E.H.3    Kang, H.E.4    Yim, I.B.5    Kim, J.Y.6    Joo, H.G.7    Woo, H.J.8
  • 64
    • 33947542115 scopus 로고    scopus 로고
    • Consumption of prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis has minor effects on selected immune parameters in polypectomised and colon cancer patients
    • Roller M, Clune Y, Collins K, Rechkemmer G, Watzl B: Consumption of prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis has minor effects on selected immune parameters in polypectomised and colon cancer patients. Br J Nutr 2007;97:676-684.
    • (2007) Br J Nutr , vol.97 , pp. 676-684
    • Roller, M.1    Clune, Y.2    Collins, K.3    Rechkemmer, G.4    Watzl, B.5
  • 65
    • 59249085585 scopus 로고    scopus 로고
    • Role of probiotic therapy in IBD
    • Isaacs K, Herfarth H: Role of probiotic therapy in IBD. Inflamm Bowel Dis 2008;14: 1597-1605.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1597-1605
    • Isaacs, K.1    Herfarth, H.2
  • 66
    • 0032800152 scopus 로고    scopus 로고
    • Prevention by chitosan of myelotoxicity, gastrointestinal toxicity and immunocompetent organic toxicity induced by 5-fluorouracil without loss of antitumor activity in mice
    • Kimura Y, Okuda H: Prevention by chitosan of myelotoxicity, gastrointestinal toxicity and immunocompetent organic toxicity induced by 5-fluorouracil without loss of antitumor activity in mice. Jpn J Cancer Res 1999;90:765-774.
    • (1999) Jpn J Cancer Res , vol.90 , pp. 765-774
    • Kimura, Y.1    Okuda, H.2
  • 67
    • 0042236701 scopus 로고    scopus 로고
    • Oral and intestinal microflora in 5-fluorouracil treated rats, translocation to cervical and mesenteric lymph nodes and effects of probiotic bacteria
    • Von Bultzingslowen I, Adlerberth I, Wold AE, Dahlen G, Jontell M: Oral and intestinal microflora in 5-fluorouracil treated rats, translocation to cervical and mesenteric lymph nodes and effects of probiotic bacteria. Oral Microbiol Immunol 2003;18:278-284.
    • (2003) Oral Microbiol Immunol , vol.18 , pp. 278-284
    • Von Bultzingslowen, I.1    Adlerberth, I.2    Wold, A.E.3    Dahlen, G.4    Jontell, M.5
  • 69
    • 0023924067 scopus 로고
    • Preservation of intestinal integrity during radiotherapy using live Lactobacillus acidophilus cultures
    • Salminen E, Elomaa I, Minkkinen J, Vapaatalo H, Salminen S: Preservation of intestinal integrity during radiotherapy using live Lactobacillus acidophilus cultures. Clin Radiol 1988;39:435-437.
    • (1988) Clin Radiol , vol.39 , pp. 435-437
    • Salminen, E.1    Elomaa, I.2    Minkkinen, J.3    Vapaatalo, H.4    Salminen, S.5
  • 70
    • 77951800189 scopus 로고    scopus 로고
    • Randomized controlled trial of live Lactobacillus acidophilus plus Bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients
    • Chitapanarux I, Chitapanarux T, Traisathit P, Kudumpee S, Tharavichitkul E, Lorvidhaya V: Randomized controlled trial of live Lactobacillus acidophilus plus Bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. Radiat Oncol 2010;5:31-37.
    • (2010) Radiat Oncol , vol.5 , pp. 31-37
    • Chitapanarux, I.1    Chitapanarux, T.2    Traisathit, P.3    Kudumpee, S.4    Tharavichitkul, E.5    Lorvidhaya, V.6
  • 71
    • 45949090411 scopus 로고    scopus 로고
    • Effects of probiotic Lactobacillus casei DN-114 001 in prevention of radiationinduced diarrhea: Results from multicenter, randomized, placebo-controlled nutritional trial
    • Giralt J, Regadera JP, Verges R, Romero J, de la Fuente I, Biete A, Villoria J, Cobo JM, Guarner F: Effects of probiotic Lactobacillus casei DN-114 001 in prevention of radiationinduced diarrhea: results from multicenter, randomized, placebo-controlled nutritional trial. Int J Radiat Oncol Biol Phys 2008;71: 1213-1219.
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , pp. 1213-1219
    • Giralt, J.1    Regadera, J.P.2    Verges, R.3    Romero, J.4    De La Fuente, I.5    Biete, A.6    Villoria, J.7    Cobo, J.M.8    Guarner, F.9
  • 72
    • 0035050218 scopus 로고    scopus 로고
    • Results of a double-blind, randomized study to evaluate the efficacy and safety of Antibiophilus in patients with radiation-induced diarrhoea
    • Urbancsek H, Kazar T, Mezes I, Neumann K: Results of a double-blind, randomized study to evaluate the efficacy and safety of Antibiophilus in patients with radiation-induced diarrhoea. Eur J Gastroenterol Hepatol 2001; 13:391-396.
    • (2001) Eur J Gastroenterol Hepatol , vol.13 , pp. 391-396
    • Urbancsek, H.1    Kazar, T.2    Mezes, I.3    Neumann, K.4
  • 73
    • 0036743774 scopus 로고    scopus 로고
    • Prophylaxis of diarrhea in patients submitted to radiotherapeutic treatment on pelvic district: Personal experience
    • Delia P, Sansotta G, Donato V, Messina G, Frosina R, Pergolizzi S, De Renzis C: Prophylaxis of diarrhea in patients submitted to radiotherapeutic treatment on pelvic district: personal experience. Dig Liver Dis 2002;34: S84-S86.
    • (2002) Dig Liver Dis , vol.34
    • Delia, P.1    Sansotta, G.2    Donato, V.3    Messina, G.4    Frosina, R.5    Pergolizzi, S.6    De Renzis, C.7
  • 75
    • 79952984155 scopus 로고    scopus 로고
    • Probiotics as prevention of radiation-induced diarrhoea
    • Timko J: Probiotics as prevention of radiation-induced diarrhoea. J Radiother Pract 2010;9:201-208.
    • (2010) J Radiother Pract , vol.9 , pp. 201-208
    • Timko, J.1
  • 78
    • 40449105862 scopus 로고    scopus 로고
    • Quality of life and symptom attribution in long-term colon cancer survivors
    • Philipps E, Braitman LE, Stites S, Leighton JC: Quality of life and symptom attribution in long-term colon cancer survivors. J Eval Clin Pract 2008;14:254-258.
    • (2008) J Eval Clin Pract , vol.14 , pp. 254-258
    • Philipps, E.1    Braitman, L.E.2    Stites, S.3    Leighton, J.C.4
  • 79
    • 80052404607 scopus 로고    scopus 로고
    • Functional outcome, quality of life, and efficacy of probiotics in postoperative patients with colorectal cancer
    • Ohigashi S, Hoshino Y, Ohde S, Onodera H: Functional outcome, quality of life, and efficacy of probiotics in postoperative patients with colorectal cancer. Surg Today 2011;41: 1200-1206.
    • (2011) Surg Today , vol.41 , pp. 1200-1206
    • Ohigashi, S.1    Hoshino, Y.2    Ohde, S.3    Onodera, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.